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Meeting Abstracts

1748-P: NMDA Receptor Is Involved in Amplification Effects of Glycine on Insulin Secretion

ZIWEI WANG, SHI MENG, DONGNA HAN, CHANGHONG LI, JUNQING ZHANG
Journal: Diabetes
Diabetes 2024;73(Supplement_1):1748-P
https://doi.org/10.2337/db24-1748-P
Published: 14 June 2024
View article titled, 1748-P: NMDA Receptor Is Involved in Amplification Effects of Glycine on Insulin Secretion
Meeting Abstracts

879-P: The Effects of the Combination of Dorzagliatin and Canagliflozin on Glucose Homeostasis in Mice

DONGNA HAN, TINGTING ZHANG, SHI MENG, LI CHEN, CHANGHONG LI
Journal: Diabetes
Diabetes 2024;73(Supplement_1):879-P
https://doi.org/10.2337/db24-879-P
Published: 14 June 2024
View article titled, 879-P: The Effects of the Combination of Dorzagliatin and Canagliflozin on Glucose Homeostasis in Mice
Meeting Abstracts

1740-P: The Effects of SGLT2 Inhibitor Canagliflozin on Glucagon Secretion in SUR1 Knockout Mice

TINGTING ZHANG, DONGNA HAN, SHI MENG, RUYUE LI, CHANGHONG LI
Journal: Diabetes
Diabetes 2024;73(Supplement_1):1740-P
https://doi.org/10.2337/db24-1740-P
Published: 14 June 2024
View article titled, 1740-P: The Effects of SGLT2 Inhibitor Canagliflozin on Glucagon Secretion in SUR1 Knockout Mice
Journal Articles

Phenotypic Characterization of Congenital Hyperinsulinism Due to Novel Activating Glucokinase Mutations

Changhong Li, Christine A. Juliana, Yue Yuan, Ming Li, Ming Lu, Pan Chen, Kara E. Boodhansingh, Nicolai M. Doliba, Tricia R. Bhatti, N. Scott Adzick, Charles A. Stanley, Diva D. De León
Journal: Diabetes
Diabetes 2023;72(12):1809–1819
https://doi.org/10.2337/db23-0465
Published: 19 September 2023
View article titled, Phenotypic Characterization of Congenital Hyperinsulinism Due to Novel Activating Glucokinase Mutations
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Meeting Abstracts

842-P: Development of Long-Acting GLP-1 Receptor Antagonist for the Treatment of Congenital Hyperinsulinism

YUE YUAN, HAOWEN JIANG, SHI MENG, DONGNA HAN, QIUSHA ZHU, MANCHEN WANG, HUSHAN LI, JIA LI, CHANGHONG LI
Journal: Diabetes
Diabetes 2023;72(Supplement_1):842-P
https://doi.org/10.2337/db23-842-P
Published: 20 June 2023
View article titled, 842-P: Development of Long-Acting GLP-1 Receptor Antagonist for the Treatment of Congenital Hyperinsulinism
Meeting Abstracts

293-LB: Dorzagliatin, a Glucokinase Activator, Restores Glucose-Sensing in Type 2 Diabetic Human Islets

JEFFEREY ROMAN, QIUSHA ZHU, YUE YUAN, CHANGHONG LI, LI CHEN, NICOLAI M. DOLIBA
Journal: Diabetes
Diabetes 2023;72(Supplement_1):293-LB
https://doi.org/10.2337/db23-293-LB
Published: 20 June 2023
View article titled, 293-LB: Dorzagliatin, a Glucokinase Activator, Restores Glucose-Sensing in Type 2 Diabetic Human Islets
Meeting Abstracts

297-LB: Dorzagliatin, a Glucokinase Activator, Repairs Defective Islet Function in High-Fat Diet-Induced Diabetic Mice

DONGNA HAN, SHI MENG, XUE ZHOU, RUYUE LI, CHANGHONG LI
Journal: Diabetes
Diabetes 2023;72(Supplement_1):297-LB
https://doi.org/10.2337/db23-297-LB
Published: 20 June 2023
View article titled, 297-LB: Dorzagliatin, a Glucokinase Activator, Repairs Defective Islet Function in High-Fat Diet-Induced Diabetic Mice
Meeting Abstracts

1581-P: Systemic Alteration of Amino Acids Metabolism in Glutamate Dehydrogenase Gain-of-Function Mutation Knockin Mice

CHANG SU, DONGNA HAN, SHI MENG, QIUSHA ZHU, XUE ZHOU, HAOWEN JIANG, JIA LI, CHUNXIU GONG, CHANGHONG LI
Journal: Diabetes
Diabetes 2023;72(Supplement_1):1581-P
https://doi.org/10.2337/db23-1581-P
Published: 20 June 2023
View article titled, 1581-P: Systemic Alteration of Amino Acids Metabolism in Glutamate Dehydrogenase Gain-of-Function Mutation Knockin Mice
Meeting Abstracts

Functional Maturation of Pancreatic ß Cells during Development

DIANA E. STANESCU, CHANGHONG LI, JUXIANG YANG, DAPHNE YAU, CHARLES A. STANLEY
Journal: Diabetes
Diabetes 2018;67(Supplement_1):2131-P
https://doi.org/10.2337/db18-2131-P
Published: 01 July 2018
View article titled, Functional Maturation of Pancreatic ß Cells during Development
Journal Articles

Functional and Metabolomic Consequences of KATP Channel Inactivation in Human Islets

Changhong Li, Amanda M. Ackermann, Kara E. Boodhansingh, Tricia R. Bhatti, Chengyang Liu, Jonathan Schug, Nicolai Doliba, Bing Han, Karen E. Cosgrove, Indraneel Banerjee, Franz M. Matschinsky, Itzhak Nissim, Klaus H. Kaestner, Ali Naji, N. Scott Adzick, Mark J. Dunne, Charles A. Stanley, Diva D. De León
Journal: Diabetes
Diabetes 2017;66(7):1901–1913
https://doi.org/10.2337/db17-0029
Published: 25 April 2017
View article titled, Functional and Metabolomic Consequences of K<sub>ATP</sub> Channel Inactivation in Human Islets
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Includes: Supplementary data
Journal Articles

A NEET Way to Impair Mitochondrial Function in α- and β-Cells

Changhong Li, Joseph A. Baur
Journal: Diabetes
Diabetes 2016;65(6):1484–1486
https://doi.org/10.2337/dbi16-0011
Published: 18 May 2016
View article titled, A NEET Way to Impair Mitochondrial Function in α- and β-Cells
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Journal Articles

Mitochondrial GTP Insensitivity Contributes to Hypoglycemia in Hyperinsulinemia Hyperammonemia by Inhibiting Glucagon Release

Richard G. Kibbey, Cheol Soo Choi, Hui-Young Lee, Over Cabrera, Rebecca L. Pongratz, Xiaojian Zhao, Andreas L. Birkenfeld, Changhong Li, Per-Olof Berggren, Charles Stanley, Gerald I. Shulman
Journal: Diabetes
Diabetes 2014;63(12):4218–4229
https://doi.org/10.2337/db14-0783
Published: 13 November 2014
View article titled, Mitochondrial GTP Insensitivity Contributes to Hypoglycemia in Hyperinsulinemia Hyperammonemia by Inhibiting Glucagon Release
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Journal Articles

Neutralizing Th2 Inflammation in Neonatal Islets Prevents β-Cell Failure in Adult IUGR Rats

Lane J. Jaeckle Santos, Changhong Li, Paschalis-Thomas Doulias, Harry Ischiropoulos, G. Scott Worthen, Rebecca A. Simmons
Journal: Diabetes
Diabetes 2014;63(5):1672–1684
https://doi.org/10.2337/db13-1226
Published: 12 April 2014
View article titled, Neutralizing Th2 Inflammation in Neonatal Islets Prevents β-Cell Failure in Adult IUGR Rats
Open the PDF for Neutralizing Th2 Inflammation in Neonatal Islets Prevents β-Cell Failure in Adult IUGR Rats in another window
Includes: Supplementary data
Journal Articles

GLP-1 Receptor Antagonist Exendin-(9-39) Elevates Fasting Blood Glucose Levels in Congenital Hyperinsulinism Owing to Inactivating Mutations in the ATP-Sensitive K+ Channel

Andrew C. Calabria, Changhong Li, Paul R. Gallagher, Charles A. Stanley, Diva D. De León
Journal: Diabetes
Diabetes 2012;61(10):2585–2591
https://doi.org/10.2337/db12-0166
Published: 13 September 2012
View article titled, GLP-1 Receptor Antagonist Exendin-(9-39) Elevates Fasting Blood Glucose Levels in Congenital Hyperinsulinism Owing to Inactivating Mutations in the ATP-Sensitive K<sup>+</sup> Channel
Open the PDF for GLP-1 Receptor Antagonist Exendin-(9-39) Elevates Fasting Blood Glucose Levels in Congenital Hyperinsulinism Owing to Inactivating Mutations in the ATP-Sensitive K<sup>+</sup> Channel in another window
Journal Articles

Glutaminolysis and Insulin Secretion: From Bedside to Bench and Back

Andrea Kelly, Changhong Li, Zhiyong Gao, Charles A. Stanley, Franz M. Matschinsky
Journal: Diabetes
Diabetes 2002;51(suppl_3):S421–S426
https://doi.org/10.2337/diabetes.51.2007.S421
Published: 01 December 2002
View article titled, Glutaminolysis and Insulin Secretion: <subtitle>From Bedside to Bench and Back </subtitle>
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