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Journal Articles

CD4⁺ T Cells From Individuals With Type 1 Diabetes Respond to a Novel Class of Deamidated Peptides Formed in Pancreatic Islets

Aïsha Callebaut, Perrin Guyer, Rita Derua, Mijke Buitinga, Anthony Manganaro, Xiaoyan Yi, Fernanda Marques Câmara Sodré, Saurabh Vig, Mara Suleiman, Piero Marchetti, Decio L. Eizirik, Sally C. Kent, Chantal Mathieu, Eddie A. James, Lut Overbergh

Diabetes 2024;73(5):728–742

https://doi.org/10.2337/db23-0588

Published: 22 February 2024

View article titled, CD4+ T Cells From Individuals With Type 1 Diabetes Respond to a Novel Class of Deamidated Peptides Formed in Pancreatic Islets

Journal Articles

An Insulin-Chromogranin A Hybrid Peptide Activates DR11-Restricted T Cells in Human Type 1 Diabetes

Aïsha Callebaut, Perrin Guyer, Rocky L. Baker, Joylynn B. Gallegos, Anita C. Hohenstein, Peter A. Gottlieb, Chantal Mathieu, Lut Overbergh, Kathryn Haskins, Eddie A. James

Diabetes 2024;73(5):743–750

https://doi.org/10.2337/db23-0622

Published: 31 January 2024

View article titled, An Insulin-Chromogranin A Hybrid Peptide Activates DR11-Restricted T Cells in Human Type 1 Diabetes

Journal Articles

A Plasma miR-193b-365 Signature Combined With Age and Glycemic Status Predicts Response to Lactococcus lactis–Based Antigen-Specific Immunotherapy in New-Onset Type 1 Diabetes

Gabriele Sassi, Giada Licata, Giuliana Ventriglia, Amber Wouters, Pierre Lemaitre, Ruth Seurinck, Alessia Mori, Giuseppina Emanuela Grieco, Samal Bissenova, Darcy Ellis, Silvia Caluwaerts, Pieter Rottiers, Niels Vandamme, Chantal Mathieu, Francesco Dotta, Conny Gysemans, Guido Sebastiani

Diabetes 2023;72(10):1470–1482

https://doi.org/10.2337/db22-0852

Published: 26 July 2023

View article titled, A Plasma miR-193b-365 Signature Combined With Age and Glycemic Status Predicts Response to Lactococcus lactis–Based Antigen-Specific Immunotherapy in New-Onset Type 1 Diabetes

Meeting Abstracts

53-OR: Efficacy and Safety of Coadministered s.c. Semaglutide and s.c. Cagrilintide in Type 2 Diabetes

JUAN P. FRIAS, SRIKANTH DEENADAYALAN, LARS ERICHSEN, FILIP K. KNOP, ILDIKO LINGVAY, STANISLAVA MACURA, CHANTAL MATHIEU, SUE D. PEDERSEN, MELANIE J. DAVIES

Diabetes 2023;72(Supplement_1):53-OR

https://doi.org/10.2337/db23-53-OR

Published: 23 June 2023

View article titled, 53-OR: Efficacy and Safety of Coadministered s.c. Semaglutide and s.c. Cagrilintide in Type 2 Diabetes

Meeting Abstracts

54-OR: Effect of Coadministered s.c. Semaglutide and s.c. Cagrilintide on Glycemic Levels Measured by CGM

CHANTAL MATHIEU, SRIKANTH DEENADAYALAN, LARS ERICHSEN, JUAN P. FRIAS, FILIP K. KNOP, ILDIKO LINGVAY, EVA W. LEHMANN, SUE D. PEDERSEN, MELANIE J. DAVIES

Diabetes 2023;72(Supplement_1):54-OR

https://doi.org/10.2337/db23-54-OR

Published: 23 June 2023

View article titled, 54-OR: Effect of Coadministered s.c. Semaglutide and s.c. Cagrilintide on Glycemic Levels Measured by CGM

Meeting Abstracts

804-P: Similar Hypoglycemia Duration with Once-Weekly Icodec vs. Degludec or Glargine U100 in Insulin-Treated T2D—A Post Hoc CGM Analysis from ONWARDS 2 and 4

HARPREET S. BAJAJ, BJÖRG ÁSBJÖRNSDÓTTIR, LISBETH CARSTENSEN, LARS LANG LEHRSKOV, CHANTAL MATHIEU, ATHENA PHILIS-TSIMIKAS, TADEJ BATTELINO

Diabetes 2023;72(Supplement_1):804-P

https://doi.org/10.2337/db23-804-P

Published: 20 June 2023

View article titled, 804-P: Similar Hypoglycemia Duration with Once-Weekly Icodec vs. Degludec or Glargine U100 in Insulin-Treated T2D—A Post Hoc CGM Analysis from ONWARDS 2 and 4

Meeting Abstracts

783-P: Baseline HOMA2-B Can Predict Tirzepatide Efficacy—Post Hoc Analysis of the SURPASS-1 and SURPASS-2 Studies

STANLEY H. HSIA, MELISSA K. THOMAS, CHANTAL MATHIEU, HUI WANG, JENNIFER PELESHOK

Diabetes 2023;72(Supplement_1):783-P

https://doi.org/10.2337/db23-783-P

Published: 20 June 2023

View article titled, 783-P: Baseline HOMA2-B Can Predict Tirzepatide Efficacy—Post Hoc Analysis of the SURPASS-1 and SURPASS-2 Studies

Meeting Abstracts

1279-P: The INNODIA Natural History Study of Children, Adolescents, and Adults Newly Diagnosed with Type 1 Diabetes

M. LOREDANA MARCOVECCHIO, CARL DELFIN, MARGO HULSMANS, LUTGART OVERBERGH, SOFIA S. PAZMINO, DIANE E. PICTON, NELE STEENACKERS, BART VAN DER SCHUEREN, ALLAIRD E.J. HENDRIKS, CHANTAL MATHIEU, INNODIA CONSORTIUM

Diabetes 2023;72(Supplement_1):1279-P

https://doi.org/10.2337/db23-1279-P

Published: 20 June 2023

View article titled, 1279-P: The INNODIA Natural History Study of Children, Adolescents, and Adults Newly Diagnosed with Type 1 Diabetes

Meeting Abstracts

810-P: Do People Living with T1D Use the Dosing Flexibility of Degludec and Does This Depend on Patient Characteristics?

YVONNE WINHOFER, ANNE KAAS, NIKOLINE N. KNUDSEN, JOHANNES H.J. MARTINY, CHANTAL MATHIEU

Diabetes 2023;72(Supplement_1):810-P

https://doi.org/10.2337/db23-810-P

Published: 20 June 2023

View article titled, 810-P: Do People Living with T1D Use the Dosing Flexibility of Degludec and Does This Depend on Patient Characteristics?

Meeting Abstracts

727-P: Glycemic Effect of Tirzepatide by Duration of Diabetes

CHRISTOPHE DE BLOCK, CHANTAL MATHIEU, HELENE SAPIN, JACEK I. KILJANSKI, JENNIFER PELESHOK

Diabetes 2022;71(Supplement_1):727-P

https://doi.org/10.2337/db22-727-P

Published: 01 June 2022

View article titled, 727-P: Glycemic Effect of Tirzepatide by Duration of Diabetes

Meeting Abstracts

646-P: Sustained Impact of Switching from Intermittently Scanned to Real-Time Continuous Glucose Monitoring in Adults with Type 1Diabetes: 24-Month Results of the ALERTT1 Trial

MARGARETHA M. VISSER, SARA CHARLEER, STEFFEN FIEUWS, CHRISTOPHE DE BLOCK, ROBERT HILBRANDS, LIESBETH VAN HUFFEL, TOON MAES, GERD VANHAVERBEKE, EVELINE L. DIRINCK, NELE MYNGHEER, CHRIS F. VERCAMMEN, FRANK NOBELS, BART KEYMEULEN, CHANTAL MATHIEU, PIETER GILLARD

Diabetes 2022;71(Supplement_1):646-P

https://doi.org/10.2337/db22-646-P

Published: 01 June 2022

View article titled, 646-P: Sustained Impact of Switching from Intermittently Scanned to Real-Time Continuous Glucose Monitoring in Adults with Type 1Diabetes: 24-Month Results of the ALERTT1 Trial

Journal Articles

Screening for Type 1 Diabetes in the General Population: A Status Report and Perspective

Emily K. Sims, Rachel E.J. Besser, Colin Dayan, Cristy Geno Rasmussen, Carla Greenbaum, Kurt J. Griffin, William Hagopian, Mikael Knip, Anna E. Long, Frank Martin, Chantal Mathieu, Marian Rewers, Andrea K. Steck, John M. Wentworth, Stephen S. Rich, Olga Kordonouri, Anette-Gabriele Ziegler, Kevan C. Herold, for the NIDDK Type 1 Diabetes TrialNet Study Group

Diabetes 2022;71(4):610–623

https://doi.org/10.2337/dbi20-0054

Published: 22 March 2022

View article titled, Screening for Type 1 Diabetes in the General Population: A Status Report and Perspective

Journal Articles

CD8⁺ T Cells Variably Recognize Native Versus Citrullinated GRP78 Epitopes in Type 1 Diabetes

Diabetes 2021;70(12):2879–2891

https://doi.org/10.2337/db21-0259

Published: 24 September 2021

View article titled, CD8+ T Cells Variably Recognize Native Versus Citrullinated GRP78 Epitopes in Type 1 Diabetes

Meeting Abstracts

675-P: Effects of Liraglutide in T1D by Baseline Anthropometrics in ADJUNCT One and Two

THOMAS F. DEJGAARD, LARS BARDTRUM, ERIK CHRISTIANSEN, FREDERIK KREINER, STEN MADSBAD, MATTHIAS G. VON HERRATH, SR., BERNT JOHAN VON SCHOLTEN, CHANTAL MATHIEU

Diabetes 2021;70(Supplement_1):675-P

https://doi.org/10.2337/db21-675-P

Published: 01 June 2021

View article titled, 675-P: Effects of Liraglutide in T1D by Baseline Anthropometrics in ADJUNCT One and Two

Meeting Abstracts

1111-P: Integrating Longitudinal Clinical and Baseline Multiomics Data for Predicting C-Peptide Progression in Newly Diagnosed Type 1 Diabetes

CAROLINE BRORSSON, JOSE JUAN ALMAGRO ARMENTEROS, GIANLUCA MAZZONI, SIMRANJEET KAUR, ANKE M. SCHULTE, CHANTAL MATHIEU, SØREN BRUNAK, ON BEHALF OF THE INNODIA CONSORTIUM

Diabetes 2021;70(Supplement_1):1111-P

https://doi.org/10.2337/db21-1111-P

Published: 01 June 2021

View article titled, 1111-P: Integrating Longitudinal Clinical and Baseline Multiomics Data for Predicting C-Peptide Progression in Newly Diagnosed Type 1 Diabetes

Meeting Abstracts

732-P: CGM-Derived Parameters for Once-Weekly Insulin Icodec vs. Once-Daily Insulin Glargine U100 in Insulin-Naïve Patients with T2D

ILDIKO LINGVAY, RIKKE BECK BANG, METTE M. KOEFOED, JULIA K. MADER, JEREMY PETTUS, LILY WAGNER, CHANTAL MATHIEU

Diabetes 2021;70(Supplement_1):732-P

https://doi.org/10.2337/db21-732-P

Published: 01 June 2021

View article titled, 732-P: CGM-Derived Parameters for Once-Weekly Insulin Icodec vs. Once-Daily Insulin Glargine U100 in Insulin-Naïve Patients with T2D

Meeting Abstracts

726-P: Glucose Control Using Fast-Acting Insulin Aspart in a Real-World Setting: A One-Year Multicenter Study in People with Type 1 Diabetes Using Continuous Glucose Monitoring

LISA BILLION, SARA CHARLEER, LAURENS VERBRAEKEN, MIRA STERCKX, KATO VANGELABBEEK, NATHALIE DE BLOCK, CHARLIEN JANSSEN, NANCY BOLSENS, EVELINE L. DIRINCK, FRIDA W. PEIFFER, KRISTOF P. VAN DESSEL, CHANTAL MATHIEU, PIETER GILLARD, CHRISTOPHE DE BLOCK

Diabetes 2021;70(Supplement_1):726-P

https://doi.org/10.2337/db21-726-P

Published: 01 June 2021

View article titled, 726-P: Glucose Control Using Fast-Acting Insulin Aspart in a Real-World Setting: A One-Year Multicenter Study in People with Type 1 Diabetes Using Continuous Glucose Monitoring

Meeting Abstracts

162-LB: Plasma Glycated CD59 Predicts Postpartum Glucose Intolerance after Gestational Diabetes

KATRIEN BENHALIMA, DONGDONG MA, MICHELLE TOTH CASTILLO, ANNOUSCHKA LAENEN, CHANTAL MATHIEU, JOSE HALPERIN

Diabetes 2021;70(Supplement_1):162-LB

https://doi.org/10.2337/db21-162-LB

Published: 01 June 2021

View article titled, 162-LB: Plasma Glycated CD59 Predicts Postpartum Glucose Intolerance after Gestational Diabetes

Journal Articles

Peptidylarginine Deiminase Inhibition Prevents Diabetes Development in NOD Mice

Fernanda M.C. Sodré, Samal Bissenova, Ylke Bruggeman, Ronak Tilvawala, Dana P. Cook, Claire Berthault, Santanu Mondal, Aïsha Callebaut, Sylvaine You, Raphael Scharfmann, Roberto Mallone, Paul R. Thompson, Chantal Mathieu, Mijke Buitinga, Lut Overbergh

Diabetes 2021;70(2):516–528

https://doi.org/10.2337/db20-0421

Published: 17 November 2020

View article titled, Peptidylarginine Deiminase Inhibition Prevents Diabetes Development in NOD Mice

Meeting Abstracts

94-LB: Long-Term Clinical Benefits of Early Combination Approach in Latin American Subpopulation of VERIFY Study

SERGIO VENCIO, JUAN MANOSALVA, CHANTAL MATHIEU, PIETER PROOT, PAIVI M. PALDANIUS

Diabetes 2020;69(Supplement_1):94-LB

https://doi.org/10.2337/db20-94-LB

Published: 01 June 2020

View article titled, 94-LB: Long-Term Clinical Benefits of Early Combination Approach in Latin American Subpopulation of VERIFY Study

NARROW

CD4⁺ T Cells From Individuals With Type 1 Diabetes Respond to a Novel Class of Deamidated Peptides Formed in Pancreatic Islets

An Insulin-Chromogranin A Hybrid Peptide Activates DR11-Restricted T Cells in Human Type 1 Diabetes

A Plasma miR-193b-365 Signature Combined With Age and Glycemic Status Predicts Response to Lactococcus lactis–Based Antigen-Specific Immunotherapy in New-Onset Type 1 Diabetes

53-OR: Efficacy and Safety of Coadministered s.c. Semaglutide and s.c. Cagrilintide in Type 2 Diabetes

54-OR: Effect of Coadministered s.c. Semaglutide and s.c. Cagrilintide on Glycemic Levels Measured by CGM

804-P: Similar Hypoglycemia Duration with Once-Weekly Icodec vs. Degludec or Glargine U100 in Insulin-Treated T2D—A Post Hoc CGM Analysis from ONWARDS 2 and 4

783-P: Baseline HOMA2-B Can Predict Tirzepatide Efficacy—Post Hoc Analysis of the SURPASS-1 and SURPASS-2 Studies

1279-P: The INNODIA Natural History Study of Children, Adolescents, and Adults Newly Diagnosed with Type 1 Diabetes

810-P: Do People Living with T1D Use the Dosing Flexibility of Degludec and Does This Depend on Patient Characteristics?

727-P: Glycemic Effect of Tirzepatide by Duration of Diabetes

646-P: Sustained Impact of Switching from Intermittently Scanned to Real-Time Continuous Glucose Monitoring in Adults with Type 1Diabetes: 24-Month Results of the ALERTT1 Trial

Screening for Type 1 Diabetes in the General Population: A Status Report and Perspective

CD8⁺ T Cells Variably Recognize Native Versus Citrullinated GRP78 Epitopes in Type 1 Diabetes

675-P: Effects of Liraglutide in T1D by Baseline Anthropometrics in ADJUNCT One and Two

1111-P: Integrating Longitudinal Clinical and Baseline Multiomics Data for Predicting C-Peptide Progression in Newly Diagnosed Type 1 Diabetes

732-P: CGM-Derived Parameters for Once-Weekly Insulin Icodec vs. Once-Daily Insulin Glargine U100 in Insulin-Naïve Patients with T2D

726-P: Glucose Control Using Fast-Acting Insulin Aspart in a Real-World Setting: A One-Year Multicenter Study in People with Type 1 Diabetes Using Continuous Glucose Monitoring

162-LB: Plasma Glycated CD59 Predicts Postpartum Glucose Intolerance after Gestational Diabetes

Peptidylarginine Deiminase Inhibition Prevents Diabetes Development in NOD Mice

94-LB: Long-Term Clinical Benefits of Early Combination Approach in Latin American Subpopulation of VERIFY Study

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