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Cheol Soo Choi
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Journal Articles

Adipocyte-Specific Deficiency of De Novo Sphingolipid Biosynthesis Leads to Lipodystrophy and Insulin Resistance

Su-Yeon Lee, Hui-Young Lee, Jae-Hwi Song, Goon-Tae Kim, Suwon Jeon, Yoo-Jeong Song, Jae Sung Lee, Jang-Ho Hur, Hyun Hee Oh, Shi-Young Park, Soon-Mi Shim, Hyun Joo Yoo, Byung Cheon Lee, Xian-Cheng Jiang, Cheol Soo Choi, Tae-Sik Park
Journal: Diabetes
Diabetes 2017;66(10):2596–2609
https://doi.org/10.2337/db16-1232
Published: 11 July 2017
View article titled, Adipocyte-Specific Deficiency of De Novo Sphingolipid Biosynthesis Leads to Lipodystrophy and Insulin Resistance
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Includes: Supplementary data
Journal Articles

Pivotal Role of O-GlcNAc Modification in Cold-Induced Thermogenesis by Brown Adipose Tissue Through Mitochondrial Biogenesis

Natsuko Ohashi, Katsutaro Morino, Shogo Ida, Osamu Sekine, Mengistu Lemecha, Shinji Kume, Shi-Young Park, Cheol Soo Choi, Satoshi Ugi, Hiroshi Maegawa
Journal: Diabetes
Diabetes 2017;66(9):2351–2362
https://doi.org/10.2337/db16-1427
Published: 21 June 2017
View article titled, Pivotal Role of <em>O</em>-GlcNAc Modification in Cold-Induced Thermogenesis by Brown Adipose Tissue Through Mitochondrial Biogenesis
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Includes: Supplementary data
Journal Articles

Mitochondrial-Targeted Catalase Protects Against High-Fat Diet–Induced Muscle Insulin Resistance by Decreasing Intramuscular Lipid Accumulation

Hui-Young Lee, Jae Sung Lee, Tiago Alves, Warren Ladiges, Peter S. Rabinovitch, Michael J. Jurczak, Cheol Soo Choi, Gerald I. Shulman, Varman T. Samuel
Journal: Diabetes
Diabetes 2017;66(8):2072–2081
https://doi.org/10.2337/db16-1334
Published: 05 May 2017
View article titled, Mitochondrial-Targeted Catalase Protects Against High-Fat Diet–Induced Muscle Insulin Resistance by Decreasing Intramuscular Lipid Accumulation
Open the PDF for Mitochondrial-Targeted Catalase Protects Against High-Fat Diet–Induced Muscle Insulin Resistance by Decreasing Intramuscular Lipid Accumulation in another window
Includes: Supplementary data
Journal Articles

Inhibition of Pyruvate Dehydrogenase Kinase 2 Protects Against Hepatic Steatosis Through Modulation of Tricarboxylic Acid Cycle Anaplerosis and Ketogenesis

Younghoon Go, Ji Yun Jeong, Nam Ho Jeoung, Jae-Han Jeon, Bo-Yoon Park, Hyeon-Ji Kang, Chae-Myeong Ha, Young-Keun Choi, Sun Joo Lee, Hye Jin Ham, Byung-Gyu Kim, Keun-Gyu Park, So Young Park, Chul-Ho Lee, Cheol Soo Choi, Tae-Sik Park, W.N. Paul Lee, Robert A. Harris, In-Kyu Lee
Journal: Diabetes
Diabetes 2016;65(10):2876–2887
https://doi.org/10.2337/db16-0223
Published: 06 July 2016
View article titled, Inhibition of Pyruvate Dehydrogenase Kinase 2 Protects Against Hepatic Steatosis Through Modulation of Tricarboxylic Acid Cycle Anaplerosis and Ketogenesis
Open the PDF for Inhibition of Pyruvate Dehydrogenase Kinase 2 Protects Against Hepatic Steatosis Through Modulation of Tricarboxylic Acid Cycle Anaplerosis and Ketogenesis in another window
Includes: Supplementary data
Journal Articles

Mitochondrial GTP Insensitivity Contributes to Hypoglycemia in Hyperinsulinemia Hyperammonemia by Inhibiting Glucagon Release

Richard G. Kibbey, Cheol Soo Choi, Hui-Young Lee, Over Cabrera, Rebecca L. Pongratz, Xiaojian Zhao, Andreas L. Birkenfeld, Changhong Li, Per-Olof Berggren, Charles Stanley, Gerald I. Shulman
Journal: Diabetes
Diabetes 2014;63(12):4218–4229
https://doi.org/10.2337/db14-0783
Published: 13 November 2014
View article titled, Mitochondrial GTP Insensitivity Contributes to Hypoglycemia in Hyperinsulinemia Hyperammonemia by Inhibiting Glucagon Release
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Journal Articles

Inverse Agonist of Nuclear Receptor ERRγ Mediates Antidiabetic Effect Through Inhibition of Hepatic Gluconeogenesis

Don-Kyu Kim, Gil-Tae Gang, Dongryeol Ryu, Minseob Koh, Yo-Na Kim, Su Sung Kim, Jinyoung Park, Yong-Hoon Kim, Taebo Sim, In-Kyu Lee, Cheol Soo Choi, Seung Bum Park, Chul-Ho Lee, Seung-Hoi Koo, Hueng-Sik Choi
Journal: Diabetes
Diabetes 2013;62(9):3093–3102
https://doi.org/10.2337/db12-0946
Published: 15 August 2013
View article titled, Inverse Agonist of Nuclear Receptor ERRγ Mediates Antidiabetic Effect Through Inhibition of Hepatic Gluconeogenesis
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Includes: Supplementary data
Journal Articles

Disruption of the Cereblon Gene Enhances Hepatic AMPK Activity and Prevents High-Fat Diet–Induced Obesity and Insulin Resistance in Mice

Kwang Min Lee, Seung-Joo Yang, Yong Deuk Kim, Yoo Duk Choi, Jong Hee Nam, Cheol Soo Choi, Hueng-Sik Choi, Chul-Seung Park
Journal: Diabetes
Diabetes 2013;62(6):1855–1864
https://doi.org/10.2337/db12-1030
Published: 17 May 2013
View article titled, Disruption of the Cereblon Gene Enhances Hepatic AMPK Activity and Prevents High-Fat Diet–Induced Obesity and Insulin Resistance in Mice
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Includes: Supplementary data
Journal Articles

Regulation of Mitochondrial Biogenesis by Lipoprotein Lipase in Muscle of Insulin-Resistant Offspring of Parents With Type 2 Diabetes

Katsutaro Morino, Kitt Falk Petersen, Saki Sono, Cheol Soo Choi, Varman T. Samuel, Aiping Lin, Amy Gallo, Hongyu Zhao, Atsunori Kashiwagi, Ira J. Goldberg, Hong Wang, Robert H. Eckel, Hiroshi Maegawa, Gerald I. Shulman
Journal: Diabetes
Diabetes 2012;61(4):877–887
https://doi.org/10.2337/db11-1391
Published: 14 March 2012
View article titled, Regulation of Mitochondrial Biogenesis by Lipoprotein Lipase in Muscle of Insulin-Resistant Offspring of Parents With Type 2 Diabetes
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Includes: Supplementary data
Journal Articles

Endoplasmic Reticulum Stress Promotes LIPIN2-Dependent Hepatic Insulin Resistance

Dongryeol Ryu, Woo-Young Seo, Young-Sil Yoon, Yo-Na Kim, Su Sung Kim, Hye-Jin Kim, Tae-Sik Park, Cheol Soo Choi, Seung-Hoi Koo
Journal: Diabetes
Diabetes 2011;60(4):1072–1081
https://doi.org/10.2337/db10-1046
Published: 22 March 2011
View article titled, Endoplasmic Reticulum Stress Promotes LIPIN2-Dependent Hepatic Insulin Resistance
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Includes: Supplementary data
Journal Articles

Paradoxical Coupling of Triglyceride Synthesis and Fatty Acid Oxidation in Skeletal Muscle Overexpressing DGAT1

Li Liu, Xiaojing Shi, Cheol Soo Choi, Gerald I. Shulman, Katherine Klaus, K. Sreekumaran Nair, Gary J. Schwartz, Yiying Zhang, Ira J. Goldberg, Yi-Hao Yu
Journal: Diabetes
Diabetes 2009;58(11):2516–2524
https://doi.org/10.2337/db08-1096
Published: 12 August 2009
View article titled, Paradoxical Coupling of Triglyceride Synthesis and Fatty Acid Oxidation in Skeletal Muscle Overexpressing DGAT1
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Includes: Supplementary data
Journal Articles

Resistance to High-Fat Diet–Induced Obesity but Exacerbated Insulin Resistance in Mice Overexpressing Preadipocyte Factor-1 (Pref-1): A New Model of Partial Lipodystrophy

Josep A. Villena, Cheol Soo Choi, Yuhui Wang, Sheene Kim, Yu-Jin Hwang, Young-Bum Kim, Gary Cline, Gerald I. Shulman, Hei Sook Sul
Journal: Diabetes
Diabetes 2008;57(12):3258–3266
https://doi.org/10.2337/db07-1739
Published: 01 December 2008
View article titled, Resistance to High-Fat Diet–Induced Obesity but Exacerbated Insulin Resistance in Mice Overexpressing Preadipocyte Factor-1 (Pref-1): <subtitle>A New Model of Partial Lipodystrophy</subtitle>
Open the PDF for Resistance to High-Fat Diet–Induced Obesity but Exacerbated Insulin Resistance in Mice Overexpressing Preadipocyte Factor-1 (Pref-1): <subtitle>A New Model of Partial Lipodystrophy</subtitle> in another window
Includes: Supplementary data
Journal Articles

Skeletal Muscle–Specific Deletion of Lipoprotein Lipase Enhances Insulin Signaling in Skeletal Muscle but Causes Insulin Resistance in Liver and Other Tissues

Hong Wang, Leslie A. Knaub, Dalan R. Jensen, Dae Young Jung, Eun-Gyoung Hong, Hwi-Jin Ko, Alison M. Coates, Ira J. Goldberg, Becky A. de la Houssaye, Rachel C. Janssen, Carrie E. McCurdy, Shaikh M. Rahman, Cheol Soo Choi, Gerald I. Shulman, Jason K. Kim, Jacob E. Friedman, Robert H. Eckel
Journal: Diabetes
Diabetes 2009;58(1):116–124
https://doi.org/10.2337/db07-1839
Published: 24 October 2008
View article titled, Skeletal Muscle–Specific Deletion of Lipoprotein Lipase Enhances Insulin Signaling in Skeletal Muscle but Causes Insulin Resistance in Liver and Other Tissues
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Journal Articles

Targeting Foxo1 in Mice Using Antisense Oligonucleotide Improves Hepatic and Peripheral Insulin Action

Varman T. Samuel, Cheol Soo Choi, Trevor G. Phillips, Anthony J. Romanelli, John G. Geisler, Sanjay Bhanot, Robert McKay, Brett Monia, John R. Shutter, Richard A. Lindberg, Gerald I. Shulman, Murielle M. Veniant
Journal: Diabetes
Diabetes 2006;55(7):2042–2050
https://doi.org/10.2337/db05-0705
Published: 01 July 2006
View article titled, Targeting Foxo1 in Mice Using Antisense Oligonucleotide Improves Hepatic and Peripheral Insulin Action
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