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Journal Articles

An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans

Robert A. Scott, Laura J. Scott, Reedik Mägi, Letizia Marullo, Kyle J. Gaulton, Marika Kaakinen, Natalia Pervjakova, Tune H. Pers, Andrew D. Johnson, John D. Eicher, Anne U. Jackson, Teresa Ferreira, Yeji Lee, Clement Ma, Valgerdur Steinthorsdottir, Gudmar Thorleifsson, Lu Qi, Natalie R. Van Zuydam, Anubha Mahajan, Han Chen, Peter Almgren, Ben F. Voight, Harald Grallert, Martina Müller-Nurasyid, Janina S. Ried, Nigel W. Rayner, Neil Robertson, Lennart C. Karssen, Elisabeth M. van Leeuwen, Sara M. Willems, Christian Fuchsberger, Phoenix Kwan, Tanya M. Teslovich, Pritam Chanda, Man Li, Yingchang Lu, Christian Dina, Dorothee Thuillier, Loic Yengo, Longda Jiang, Thomas Sparso, Hans A. Kestler, Himanshu Chheda, Lewin Eisele, Stefan Gustafsson, Mattias Frånberg, Rona J. Strawbridge, Rafn Benediktsson, Astradur B. Hreidarsson, Augustine Kong, Gunnar Sigurðsson, Nicola D. Kerrison, Jian'an Luan, Liming Liang, Thomas Meitinger, Michael Roden, Barbara Thorand, Tõnu Esko, Evelin Mihailov, Caroline Fox, Ching-Ti Liu, Denis Rybin, Bo Isomaa, Valeriya Lyssenko, Tiinamaija Tuomi, David J. Couper, James S. Pankow, Niels Grarup, Christian T. Have, Marit E. Jørgensen, Torben Jørgensen, Allan Linneberg, Marilyn C. Cornelis, Rob M. van Dam, David J. Hunter, Peter Kraft, Qi Sun, Sarah Edkins, Katharine R. Owen, John R.B. Perry, Andrew R. Wood, Eleftheria Zeggini, Juan Tajes-Fernandes, Goncalo R. Abecasis, Lori L. Bonnycastle, Peter S. Chines, Heather M. Stringham, Heikki A. Koistinen, Leena Kinnunen, Bengt Sennblad, Thomas W. Mühleisen, Markus M. Nöthen, Sonali Pechlivanis, Damiano Baldassarre, Karl Gertow, Steve E. Humphries, Elena Tremoli, Norman Klopp, Julia Meyer, Gerald Steinbach, Roman Wennauer, Johan G. Eriksson, Satu Mӓnnistö, Leena Peltonen, Emmi Tikkanen, Guillaume Charpentier, Elodie Eury, Stéphane Lobbens, Bruna Gigante, Karin Leander, Olga McLeod, Erwin P. Bottinger, Omri Gottesman, Douglas Ruderfer, Matthias Blüher, Peter Kovacs, Anke Tonjes, Nisa M. Maruthur, Chiara Scapoli, Raimund Erbel, Karl-Heinz Jöckel, Susanne Moebus, Ulf de Faire, Anders Hamsten, Michael Stumvoll, Panagiotis Deloukas, Peter J. Donnelly, Timothy M. Frayling, Andrew T. Hattersley, Samuli Ripatti, Veikko Salomaa, Nancy L. Pedersen, Bernhard O. Boehm, Richard N. Bergman, Francis S. Collins, Karen L. Mohlke, Jaakko Tuomilehto, Torben Hansen, Oluf Pedersen, Inês Barroso, Lars Lannfelt, Erik Ingelsson, Lars Lind, Cecilia M. Lindgren, Stephane Cauchi, Philippe Froguel, Ruth J.F. Loos, Beverley Balkau, Heiner Boeing, Paul W. Franks, Aurelio Barricarte Gurrea, Domenico Palli, Yvonne T. van der Schouw, David Altshuler, Leif C. Groop, Claudia Langenberg, Nicholas J. Wareham, Eric Sijbrands, Cornelia M. van Duijn, Jose C. Florez, James B. Meigs, Eric Boerwinkle, Christian Gieger, Konstantin Strauch, Andres Metspalu, Andrew D. Morris, Colin N.A. Palmer, Frank B. Hu, Unnur Thorsteinsdottir, Kari Stefansson, Josée Dupuis, Andrew P. Morris, Michael Boehnke, Mark I. McCarthy, Inga Prokopenko

Diabetes 2017;66(11):2888–2902

https://doi.org/10.2337/db16-1253

Published: 31 May 2017

View article titled, An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans

Includes: Supplementary data

Journal Articles

Genetic and Functional Assessment of the Role of the rs13431652-A and rs573225-A Alleles in the G6PC2 Promoter That Are Strongly Associated With Elevated Fasting Glucose Levels

Diabetes 2010;59(10):2662–2671

https://doi.org/10.2337/db10-0389

Published: 09 July 2010

View article titled, Genetic and Functional Assessment of the Role of the rs13431652-A and rs573225-A Alleles in the G6PC2 Promoter That Are Strongly Associated With Elevated Fasting Glucose Levels

Includes: Supplementary data

Journal Articles

Genetic Variant in HK1 Is Associated With a Proanemic State and A1C but Not Other Glycemic Control–Related Traits

Diabetes 2009;58(11):2687–2697

https://doi.org/10.2337/db09-0652

Published: 03 August 2009

View article titled, Genetic Variant in HK1 Is Associated With a Proanemic State and A1C but Not Other Glycemic Control–Related Traits

Includes: Supplementary data

Journal Articles

G-allele of Intronic rs10830963 in MTNR1B Confers Increased Risk of Impaired Fasting Glycemia and Type 2 Diabetes Through an Impaired Glucose-Stimulated Insulin Release: Studies Involving 19,605 Europeans

Diabetes 2009;58(6):1450–1456

https://doi.org/10.2337/db08-1660

Published: 26 March 2009

View article titled, G-allele of Intronic rs10830963 in MTNR1B Confers Increased Risk of Impaired Fasting Glycemia and Type 2 Diabetes Through an Impaired Glucose-Stimulated Insulin Release: <subtitle>Studies Involving 19,605 Europeans</subtitle>

Includes: Supplementary data

Journal Articles

Prevalence of Melanocortin-4 Receptor Deficiency in Europeans and Their Age-Dependent Penetrance in Multigenerational Pedigrees

Fanny Stutzmann, Karen Tan, Vincent Vatin, Christian Dina, Béatrice Jouret, Jean Tichet, Beverley Balkau, Natascha Potoczna, Fritz Horber, Stephen O'Rahilly, I. Sadaf Farooqi, Philippe Froguel, David Meyre

Diabetes 2008;57(9):2511–2518

https://doi.org/10.2337/db08-0153

Published: 01 September 2008

View article titled, Prevalence of Melanocortin-4 Receptor Deficiency in Europeans and Their Age-Dependent Penetrance in Multigenerational Pedigrees

Includes: Supplementary data

Journal Articles

Impact of Common Type 2 Diabetes Risk Polymorphisms in the DESIR Prospective Study

Martine Vaxillaire, Jacques Veslot, Christian Dina, Christine Proença, Stéphane Cauchi, Guillaume Charpentier, Jean Tichet, Frédéric Fumeron, Michel Marre, David Meyre, Beverley Balkau, Philippe Froguel, for the DESIR Study Group

Diabetes 2008;57(1):244–254

https://doi.org/10.2337/db07-0615

Published: 01 January 2008

View article titled, Impact of Common Type 2 Diabetes Risk Polymorphisms in the DESIR Prospective Study

Includes: Supplementary data

Journal Articles

TCF7L2 Variation Predicts Hyperglycemia Incidence in a French General Population : The Data From an Epidemiological Study on the Insulin Resistance Syndrome (DESIR) Study

Stéphane Cauchi, David Meyre, Hélène Choquet, Christian Dina, Catherine Born, Michel Marre, Beverley Balkau, Philippe Froguel, for the DESIR Study Group

Diabetes 2006;55(11):3189–3192

https://doi.org/10.2337/db06-0692

Published: 01 November 2006

View article titled, TCF7L2 Variation Predicts Hyperglycemia Incidence in a French General Population : <subtitle>The Data From an Epidemiological Study on the Insulin Resistance Syndrome (DESIR) Study</subtitle>

Includes: Supplementary data

Journal Articles

Transcription Factor TCF7L2 Genetic Study in the French Population: Expression in Human β-Cells and Adipose Tissue and Strong Association With Type 2 Diabetes

Stéphane Cauchi, David Meyre, Christian Dina, Hélène Choquet, Chantal Samson, Sophie Gallina, Beverley Balkau, Guillaume Charpentier, François Pattou, Volodymyr Stetsyuk, Raphaël Scharfmann, Bart Staels, Gema Frühbeck, Philippe Froguel

Diabetes 2006;55(10):2903–2908

https://doi.org/10.2337/db06-0474

Published: 01 October 2006

View article titled, Transcription Factor TCF7L2 Genetic Study in the French Population: <subtitle>Expression in Human β-Cells and Adipose Tissue and Strong Association With Type 2 Diabetes</subtitle>

Includes: Supplementary data

Journal Articles

EIF4A2 Is a Positional Candidate Gene at the 3q27 Locus Linked to Type 2 Diabetes in French Families

Claire Cheyssac, Christian Dina, Frédéric Leprêtre, Valérie Vasseur-Delannoy, Aurélie Dechaume, Stéphane Lobbens, Beverley Balkau, Juan Ruiz, Guillaume Charpentier, François Pattou, Erik Joly, Marc Prentki, Torben Hansen, Oluf Pedersen, Martine Vaxillaire, Philippe Froguel

Diabetes 2006;55(4):1171–1176

https://doi.org/10.2337/diabetes.55.04.06.db05-1298

Published: 01 April 2006

View article titled, EIF4A2 Is a Positional Candidate Gene at the 3q27 Locus Linked to Type 2 Diabetes in French Families

Includes: Supplementary data

Journal Articles

Genetic Analysis of ADIPOR1 and ADIPOR2 Candidate Polymorphisms for Type 2 Diabetes in the Caucasian Population

Martine Vaxillaire, Aurélie Dechaume, Valérie Vasseur-Delannoy, Saida Lahmidi, Vincent Vatin, Frédéric Leprêtre, Philippe Boutin, Serge Hercberg, Guillaume Charpentier, Christian Dina, Philippe Froguel

Diabetes 2006;55(3):856–861

https://doi.org/10.2337/diabetes.55.03.06.db05-0665

Published: 01 March 2006

View article titled, Genetic Analysis of ADIPOR1 and ADIPOR2 Candidate Polymorphisms for Type 2 Diabetes in the Caucasian Population

Includes: Supplementary data

Journal Articles

ACDC/Adiponectin Polymorphisms Are Associated With Severe Childhood and Adult Obesity

Nabila Bouatia-Naji, David Meyre, Stéphane Lobbens, Karin Séron, Frédéric Fumeron, Beverley Balkau, Barbara Heude, Béatrice Jouret, Philipp E. Scherer, Christian Dina, Jacques Weill, Philippe Froguel

Diabetes 2006;55(2):545–550

https://doi.org/10.2337/diabetes.55.02.06.db05-0971

Published: 01 February 2006

View article titled, ACDC/Adiponectin Polymorphisms Are Associated With Severe Childhood and Adult Obesity

Includes: Supplementary data

Journal Articles

Polymorphisms in the Amino Acid Transporter Solute Carrier Family 6 (Neurotransmitter Transporter) Member 14 Gene Contribute to Polygenic Obesity in French Caucasians

Emmanuelle Durand, Philippe Boutin, David Meyre, M. Aline Charles, Karine Clement, Christian Dina, Philippe Froguel

Diabetes 2004;53(9):2483–2486

https://doi.org/10.2337/diabetes.53.9.2483

Published: 01 September 2004

View article titled, Polymorphisms in the Amino Acid Transporter Solute Carrier Family 6 (Neurotransmitter Transporter) Member 14 Gene Contribute to Polygenic Obesity in French Caucasians

Journal Articles

Genome-wide Linkage Analysis for Severe Obesity in French Caucasians Finds Significant Susceptibility Locus on Chromosome 19q

Christopher G. Bell, Michael Benzinou, Afshan Siddiq, Cécile Lecoeur, Christian Dina, Arnaud Lemainque, Karine Clément, Arnaud Basdevant, Bernard Guy-Grand, Charles A. Mein, David Meyre, Philippe Froguel

Diabetes 2004;53(7):1857–1865

https://doi.org/10.2337/diabetes.53.7.1857

Published: 01 July 2004

View article titled, Genome-wide Linkage Analysis for Severe Obesity in French Caucasians Finds Significant Susceptibility Locus on Chromosome 19q

Journal Articles

A Genome-Wide Scan for Childhood Obesity–Associated Traits in French Families Shows Significant Linkage on Chromosome 6q22.31-q23.2

David Meyre, Cécile Lecoeur, Jérôme Delplanque, Stephan Francke, Vincent Vatin, Emmanuelle Durand, Jacques Weill, Christian Dina, Philippe Froguel

Diabetes 2004;53(3):803–811

https://doi.org/10.2337/diabetes.53.3.803

Published: 01 March 2004

View article titled, A Genome-Wide Scan for Childhood Obesity–Associated Traits in French Families Shows Significant Linkage on Chromosome 6q22.31-q23.2

Journal Articles

A Genome-Wide Scan in Families With Maturity-Onset Diabetes of the Young: Evidence for Further Genetic Heterogeneity

Diabetes 2003;52(3):872–881

https://doi.org/10.2337/diabetes.52.3.872

Published: 01 March 2003

View article titled, A Genome-Wide Scan in Families With Maturity-Onset Diabetes of the Young: <subtitle>Evidence for Further Genetic Heterogeneity </subtitle>

Journal Articles

A Quantitative Trait Locus Influencing Type 2 Diabetes Susceptibility Maps to a Region on 5q in an Extended French Family

Lisa J. Martin, Anthony G. Comuzzie, Sophie Dupont, Nathalie Vionnet, Christian Dina, Sophie Gallina, Mouna Houari, John Blangero, Philippe Froguel

Diabetes 2002;51(12):3568–3572

https://doi.org/10.2337/diabetes.51.12.3568

Published: 01 December 2002

View article titled, A Quantitative Trait Locus Influencing Type 2 Diabetes Susceptibility Maps to a Region on 5q in an Extended French Family

Journal Articles

Positional Candidate Gene Analysis of Lim Domain Homeobox Gene (Isl-1) on Chromosome 5q11-q13 in a French Morbidly Obese Population Suggests Indication for Association With Type 2 Diabetes

Mouna Barat-Houari, Karine Clément, Vincent Vatin, Christian Dina, Geneviève Bonhomme, Francis Vasseur, Bernard Guy-Grand, Philippe Froguel

Diabetes 2002;51(5):1640–1643

https://doi.org/10.2337/diabetes.51.5.1640

Published: 01 May 2002

View article titled, Positional Candidate Gene Analysis of Lim Domain Homeobox Gene (Isl-1) on Chromosome 5q11-q13 in a French Morbidly Obese Population Suggests Indication for Association With Type 2 Diabetes

Includes: Supplementary data

Journal Articles

Genome-Wide Search for Type 2 Diabetes in Japanese Affected Sib-Pairs Confirms Susceptibility Genes on 3q, 15q, and 20q and Identifies Two New Candidate Loci on 7p and 11p

Yasumichi Mori, Shuichi Otabe, Christian Dina, Kazuki Yasuda, Céline Populaire, Cécile Lecoeur, Vincent Vatin, Emmanuelle Durand, Kazuo Hara, Terumasa Okada, Kazuyuki Tobe, Philippe Boutin, Takashi Kadowaki, Philippe Froguel

Diabetes 2002;51(4):1247–1255

https://doi.org/10.2337/diabetes.51.4.1247

Published: 01 April 2002

View article titled, Genome-Wide Search for Type 2 Diabetes in Japanese Affected Sib-Pairs Confirms Susceptibility Genes on 3q, 15q, and 20q and Identifies Two New Candidate Loci on 7p and 11p

Journal Articles

Genetic Variation in the Gene Encoding Adiponectin Is Associated With an Increased Risk of Type 2 Diabetes in the Japanese Population

Diabetes 2002;51(2):536–540

https://doi.org/10.2337/diabetes.51.2.536

Published: 01 February 2002

View article titled, Genetic Variation in the Gene Encoding Adiponectin Is Associated With an Increased Risk of Type 2 Diabetes in the Japanese Population

Includes: Supplementary data

Journal Articles

Genetic Studies of the Sulfonylurea Receptor Gene Locus in NIDDM and in Morbid Obesity Among French Caucasians

El Habib Hani, Karine Clément, Gilberto Velho, Nathalie Vionnet, Jörg Hager, Anne Philippi, Christian Dina, Hiroshi Inoue, M Alan Permutt, Arnaud Basdevant, Michael North, Florence Demenais, Bernard Guy-Grand, Philippe Froguel

Diabetes 1997;46(4):688–694

https://doi.org/10.2337/diab.46.4.688

Published: 01 April 1997

View article titled, Genetic Studies of the Sulfonylurea Receptor Gene Locus in NIDDM and in Morbid Obesity Among French Caucasians

NARROW

An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans

Genetic and Functional Assessment of the Role of the rs13431652-A and rs573225-A Alleles in the G6PC2 Promoter That Are Strongly Associated With Elevated Fasting Glucose Levels

Genetic Variant in HK1 Is Associated With a Proanemic State and A1C but Not Other Glycemic Control–Related Traits

G-allele of Intronic rs10830963 in MTNR1B Confers Increased Risk of Impaired Fasting Glycemia and Type 2 Diabetes Through an Impaired Glucose-Stimulated Insulin Release: Studies Involving 19,605 Europeans

Prevalence of Melanocortin-4 Receptor Deficiency in Europeans and Their Age-Dependent Penetrance in Multigenerational Pedigrees

Impact of Common Type 2 Diabetes Risk Polymorphisms in the DESIR Prospective Study

TCF7L2 Variation Predicts Hyperglycemia Incidence in a French General Population : The Data From an Epidemiological Study on the Insulin Resistance Syndrome (DESIR) Study

Transcription Factor TCF7L2 Genetic Study in the French Population: Expression in Human β-Cells and Adipose Tissue and Strong Association With Type 2 Diabetes

EIF4A2 Is a Positional Candidate Gene at the 3q27 Locus Linked to Type 2 Diabetes in French Families

Genetic Analysis of ADIPOR1 and ADIPOR2 Candidate Polymorphisms for Type 2 Diabetes in the Caucasian Population

ACDC/Adiponectin Polymorphisms Are Associated With Severe Childhood and Adult Obesity

Polymorphisms in the Amino Acid Transporter Solute Carrier Family 6 (Neurotransmitter Transporter) Member 14 Gene Contribute to Polygenic Obesity in French Caucasians

Genome-wide Linkage Analysis for Severe Obesity in French Caucasians Finds Significant Susceptibility Locus on Chromosome 19q

A Genome-Wide Scan for Childhood Obesity–Associated Traits in French Families Shows Significant Linkage on Chromosome 6q22.31-q23.2

A Genome-Wide Scan in Families With Maturity-Onset Diabetes of the Young: Evidence for Further Genetic Heterogeneity

A Quantitative Trait Locus Influencing Type 2 Diabetes Susceptibility Maps to a Region on 5q in an Extended French Family

Positional Candidate Gene Analysis of Lim Domain Homeobox Gene (Isl-1) on Chromosome 5q11-q13 in a French Morbidly Obese Population Suggests Indication for Association With Type 2 Diabetes

Genome-Wide Search for Type 2 Diabetes in Japanese Affected Sib-Pairs Confirms Susceptibility Genes on 3q, 15q, and 20q and Identifies Two New Candidate Loci on 7p and 11p

Genetic Variation in the Gene Encoding Adiponectin Is Associated With an Increased Risk of Type 2 Diabetes in the Japanese Population

Genetic Studies of the Sulfonylurea Receptor Gene Locus in NIDDM and in Morbid Obesity Among French Caucasians

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