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Journal Articles

Mitofusins Mfn1 and Mfn2 Are Required to Preserve Glucose- but Not Incretin-Stimulated β-Cell Connectivity and Insulin Secretion

Diabetes 2022;71(7):1472–1489

Published: 26 April 2022

View article titled, Mitofusins Mfn1 and Mfn2 Are Required to Preserve Glucose- but Not Incretin-Stimulated β-Cell Connectivity and Insulin Secretion

Meeting Abstracts

38-OR: Deletion of the Mitofusins 1 and 2 (Mfn1 and Mfn2) from the Pancreatic Beta Cell Disrupts Mitochondrial Structure and Impairs Glucose-, but Not Incretin-, Stimulated Insulin Secretion

ELENI GEORGIADOU, CHARANYA MURALIDHARAN, PAULINE L. CHABOSSEAU, ALEJANDRA TOMAS, THEODOROS STYLIANIDES, CRISTINA LEGIDO-QUIGLEY, NOUR ALSABEEH, CÉLINE CRUCIANI-GUGLIELMACCI, CHRISTOPHE MAGNAN, MARK IBBERSON, ISABELLE LECLERC, AMELIA K. LINNEMANN, YUSUF ALI, TRISTAN RODRIGUEZ, GUY A. RUTTER

Diabetes 2021;70(Supplement_1):38-OR

https://doi.org/10.2337/db21-38-OR

Published: 01 June 2021

View article titled, 38-OR: Deletion of the Mitofusins 1 and 2 (Mfn1 and Mfn2) from the Pancreatic Beta Cell Disrupts Mitochondrial Structure and Impairs Glucose-, but Not Incretin-, Stimulated Insulin Secretion

Meeting Abstracts

1064-P: The Human Recombinant REG3A Protein ALF-5755 Restores Glucose Homeostasis and Insulin Sensitivity in High-Fat Fed Mice and in Ob/Ob Mice

MARION DARNAUD, CÉLINE CRUCIANI-GUGLIELMACCI, PATRICK GONZALEZ, PAUL AMOUYAL, GILLES AMOUYAL, LAURE JAMOT, NICOLAS MONIAUX, FABRIZIO ANDREELLI, CHRISTIAN B. BRÉCHOT, CHRISTOPHE MAGNAN, JAMILA FAIVRE

Diabetes 2020;69(Supplement_1):1064-P

https://doi.org/10.2337/db20-1064-P

Published: 01 June 2020

View article titled, 1064-P: The Human Recombinant REG3A Protein ALF-5755 Restores Glucose Homeostasis and Insulin Sensitivity in High-Fat Fed Mice and in Ob/Ob Mice

Meeting Abstracts

1955-P: Interleukin-1ß Orchestrates Non–Glucose Dependent Cephalic Phase Insulin Release in Health and Obesity

SOPHIA J. WIEDEMANN, EREZ DROR, DANIEL T. MEIER, KELLY TRIMIGLIOZZI, JOSE ALBERTO MOLINA-TIJERAS, FRIEDERIKE SCHULZE, LEILA RACHID, STÉPHANIE P. HÄUSELMANN, THERESA V. ROHM, HELENE MEREAU, CHRISTOPHE MAGNAN, MARIANNE BOENI-SCHNETZLER, MARC Y. DONATH

Diabetes 2020;69(Supplement_1):1955-P

https://doi.org/10.2337/db20-1955-P

Published: 01 June 2020

View article titled, 1955-P: Interleukin-1ß Orchestrates Non–Glucose Dependent Cephalic Phase Insulin Release in Health and Obesity

Journal Articles

Adipocyte Glucocorticoid Receptor Deficiency Promotes Adipose Tissue Expandability and Improves the Metabolic Profile Under Corticosterone Exposure

Héloïse Dalle, Marie Garcia, Bénédicte Antoine, Vanessa Boehm, Thi Thu Huong Do, Marion Buyse, Tatiana Ledent, Antonin Lamazière, Christophe Magnan, Catherine Postic, Raphaël George Denis, Serge Luquet, Bruno Fève, Marthe Moldes

Diabetes 2019;68(2):305–317

https://doi.org/10.2337/db17-1577

Published: 19 November 2018

View article titled, Adipocyte Glucocorticoid Receptor Deficiency Promotes Adipose Tissue Expandability and Improves the Metabolic Profile Under Corticosterone Exposure

Includes: Supplementary data

Journal Articles

Disruption of Lipid Uptake in Astroglia Exacerbates Diet-Induced Obesity

Yuanqing Gao, Clarita Layritz, Beata Legutko, Thomas O. Eichmann, Elise Laperrousaz, Valentine S. Moullé, Celine Cruciani-Guglielmacci, Christophe Magnan, Serge Luquet, Stephen C. Woods, Robert H. Eckel, Chun-Xia Yi, Cristina Garcia-Caceres, Matthias H. Tschöp

Diabetes 2017;66(10):2555–2563

https://doi.org/10.2337/db16-1278

Published: 14 July 2017

View article titled, Disruption of Lipid Uptake in Astroglia Exacerbates Diet-Induced Obesity

Includes: Supplementary data

Journal Articles

Sorcin Links Pancreatic β-Cell Lipotoxicity to ER Ca²⁺ Stores

Alice Marmugi, Julia Parnis, Xi Chen, LeAnne Carmichael, Julie Hardy, Naila Mannan, Piero Marchetti, Lorenzo Piemonti, Domenico Bosco, Paul Johnson, James A.M. Shapiro, Céline Cruciani-Guglielmacci, Christophe Magnan, Mark Ibberson, Bernard Thorens, Héctor H. Valdivia, Guy A. Rutter, Isabelle Leclerc

Diabetes 2016;65(4):1009–1021

https://doi.org/10.2337/db15-1334

Published: 28 January 2016

View article titled, Sorcin Links Pancreatic β-Cell Lipotoxicity to ER Ca2+ Stores

Includes: Supplementary data

Journal Articles

FAT/CD36: A Major Regulator of Neuronal Fatty Acid Sensing and Energy Homeostasis in Rats and Mice

Christelle Le Foll, Ambrose Dunn-Meynell, Serguei Musatov, Christophe Magnan, Barry E. Levin

Diabetes 2013;62(8):2709–2716

https://doi.org/10.2337/db12-1689

Published: 17 July 2013

View article titled, FAT/CD36: A Major Regulator of Neuronal Fatty Acid Sensing and Energy Homeostasis in Rats and Mice

Includes: Supplementary data

Journal Articles

GLUT2 Accumulation in Enterocyte Apical and Intracellular Membranes: A Study in Morbidly Obese Human Subjects and ob/ob and High Fat–Fed Mice

Amal Ait-Omar, Milena Monteiro-Sepulveda, Christine Poitou, Maude Le Gall, Aurélie Cotillard, Jules Gilet, Kevin Garbin, Anne Houllier, Danièle Château, Amélie Lacombe, Nicolas Veyrie, Danielle Hugol, Joan Tordjman, Christophe Magnan, Patricia Serradas, Karine Clément, Armelle Leturque, Edith Brot-Laroche

Diabetes 2011;60(10):2598–2607

https://doi.org/10.2337/db10-1740

Published: 16 September 2011

View article titled, GLUT2 Accumulation in Enterocyte Apical and Intracellular Membranes: <subtitle>A Study in Morbidly Obese Human Subjects and ob/ob and High Fat–Fed Mice</subtitle>

Includes: Supplementary data

Journal Articles

Ventromedial Hypothalamic Nitric Oxide Production Is Necessary for Hypoglycemia Detection and Counterregulation

Xavier Fioramonti, Nicolas Marsollier, Zhentao Song, Kurt A. Fakira, Reema M. Patel, Stacey Brown, Thibaut Duparc, Arnaldo Pica-Mendez, Nicole M. Sanders, Claude Knauf, Philippe Valet, Rory J. McCrimmon, Annie Beuve, Christophe Magnan, Vanessa H. Routh

Diabetes 2010;59(2):519–528

https://doi.org/10.2337/db09-0421

Published: 23 November 2009

View article titled, Ventromedial Hypothalamic Nitric Oxide Production Is Necessary for Hypoglycemia Detection and Counterregulation

Includes: Supplementary data

Journal Articles

Enhanced Hypothalamic Glucose Sensing in Obesity: Alteration of Redox Signaling

Anne-Laure Colombani, Lionel Carneiro, Alexandre Benani, Anne Galinier, Tristan Jaillard, Thibaut Duparc, Géraldine Offer, Anne Lorsignol, Christophe Magnan, Louis Casteilla, Luc Pénicaud, Corinne Leloup

Diabetes 2009;58(10):2189–2197

https://doi.org/10.2337/db09-0110

Published: 06 July 2009

View article titled, Enhanced Hypothalamic Glucose Sensing in Obesity: Alteration of Redox Signaling

Includes: Supplementary data

Journal Articles

Mitochondrial Reactive Oxygen Species Are Obligatory Signals for Glucose-Induced Insulin Secretion

Corinne Leloup, Cécile Tourrel-Cuzin, Christophe Magnan, Melis Karaca, Julien Castel, Lionel Carneiro, Anne-Laure Colombani, Alain Ktorza, Louis Casteilla, Luc Pénicaud

Diabetes 2009;58(3):673–681

https://doi.org/10.2337/db07-1056

Published: 01 March 2009

View article titled, Mitochondrial Reactive Oxygen Species Are Obligatory Signals for Glucose-Induced Insulin Secretion

Journal Articles

Brain Glucagon-Like Peptide-1 Regulates Arterial Blood Flow, Heart Rate, and Insulin Sensitivity

Cendrine Cabou, Gérard Campistron, Nicolas Marsollier, Corinne Leloup, Celine Cruciani-Guglielmacci, Luc Pénicaud, Daniel J. Drucker, Christophe Magnan, Rémy Burcelin

Diabetes 2008;57(10):2577–2587

https://doi.org/10.2337/db08-0121

Published: 01 October 2008

View article titled, Brain Glucagon-Like Peptide-1 Regulates Arterial Blood Flow, Heart Rate, and Insulin Sensitivity

Journal Articles

mTOR Inhibition by Rapamycin Prevents β-Cell Adaptation to Hyperglycemia and Exacerbates the Metabolic State in Type 2 Diabetes

Merav Fraenkel, Mali Ketzinel-Gilad, Yafa Ariav, Orit Pappo, Melis Karaca, Julien Castel, Marie-France Berthault, Christophe Magnan, Erol Cerasi, Nurit Kaiser, Gil Leibowitz

Diabetes 2008;57(4):945–957

https://doi.org/10.2337/db07-0922

Published: 01 April 2008

View article titled, mTOR Inhibition by Rapamycin Prevents β-Cell Adaptation to Hyperglycemia and Exacerbates the Metabolic State in Type 2 Diabetes

Includes: Supplementary data

Journal Articles

Insulin Internalizes GLUT2 in the Enterocytes of Healthy but Not Insulin-Resistant Mice

Vanessa Tobin, Maude Le Gall, Xavier Fioramonti, Emilie Stolarczyk, Alba G. Blazquez, Christophe Klein, Magali Prigent, Patricia Serradas, Marie-Hélène Cuif, Christophe Magnan, Armelle Leturque, Edith Brot-Laroche

Diabetes 2008;57(3):555–562

https://doi.org/10.2337/db07-0928

Published: 01 March 2008

View article titled, Insulin Internalizes GLUT2 in the Enterocytes of Healthy but Not Insulin-Resistant Mice

Includes: Supplementary data

Journal Articles

Fatty Acid Signaling in the Hypothalamus and the Neural Control of Insulin Secretion

Stéphanie Migrenne, Céline Cruciani-Guglielmacci, Ling Kang, Ruokun Wang, Claude Rouch, Anne-Laure Lefèvre, Alain Ktorza, Vanessa H. Routh, Barry E. Levin, Christophe Magnan

Diabetes 2006;55(Supplement_2):S139–S144

https://doi.org/10.2337/db06-S017

Published: 01 December 2006

View article titled, Fatty Acid Signaling in the Hypothalamus and the Neural Control of Insulin Secretion

Journal Articles

Mitochondrial Reactive Oxygen Species Are Required for Hypothalamic Glucose Sensing

Corinne Leloup, Christophe Magnan, Alexandre Benani, Emilie Bonnet, Thierry Alquier, Géraldine Offer, Audrey Carriere, Alain Périquet, Yvette Fernandez, Alain Ktorza, Louis Casteilla, Luc Pénicaud

Diabetes 2006;55(7):2084–2090

https://doi.org/10.2337/db06-0086

Published: 01 July 2006

View article titled, Mitochondrial Reactive Oxygen Species Are Required for Hypothalamic Glucose Sensing

Journal Articles

Psammomys Obesus, a Model for Environment-Gene Interactions in Type 2 Diabetes

Nurit Kaiser, Rafael Nesher, Marc Y. Donath, Merav Fraenkel, Vered Behar, Christophe Magnan, Alain Ktorza, Erol Cerasi, Gil Leibowitz

Diabetes 2005;54(suppl_2):S137–S144

https://doi.org/10.2337/diabetes.54.suppl_2.S137

Published: 01 December 2005

View article titled, Psammomys Obesus, a Model for Environment-Gene Interactions in Type 2 Diabetes

Journal Articles

Leptin Receptor−Deficient Obese Zucker Rats Reduce Their Food Intake in Response to a Systemic Supply of Calories From Glucose

Marc Gilbert, Christophe Magnan, Sophie Turban, Jocelyne André, Michèle Guerre-Millo

Diabetes 2003;52(2):277–282

https://doi.org/10.2337/diabetes.52.2.277

Published: 01 February 2003

View article titled, Leptin Receptor−Deficient Obese Zucker Rats Reduce Their Food Intake in Response to a Systemic Supply of Calories From Glucose

NARROW

Mitofusins Mfn1 and Mfn2 Are Required to Preserve Glucose- but Not Incretin-Stimulated β-Cell Connectivity and Insulin Secretion

38-OR: Deletion of the Mitofusins 1 and 2 (Mfn1 and Mfn2) from the Pancreatic Beta Cell Disrupts Mitochondrial Structure and Impairs Glucose-, but Not Incretin-, Stimulated Insulin Secretion

1064-P: The Human Recombinant REG3A Protein ALF-5755 Restores Glucose Homeostasis and Insulin Sensitivity in High-Fat Fed Mice and in Ob/Ob Mice

1955-P: Interleukin-1ß Orchestrates Non–Glucose Dependent Cephalic Phase Insulin Release in Health and Obesity

Adipocyte Glucocorticoid Receptor Deficiency Promotes Adipose Tissue Expandability and Improves the Metabolic Profile Under Corticosterone Exposure

Disruption of Lipid Uptake in Astroglia Exacerbates Diet-Induced Obesity

Sorcin Links Pancreatic β-Cell Lipotoxicity to ER Ca²⁺ Stores

FAT/CD36: A Major Regulator of Neuronal Fatty Acid Sensing and Energy Homeostasis in Rats and Mice

GLUT2 Accumulation in Enterocyte Apical and Intracellular Membranes: A Study in Morbidly Obese Human Subjects and ob/ob and High Fat–Fed Mice

Ventromedial Hypothalamic Nitric Oxide Production Is Necessary for Hypoglycemia Detection and Counterregulation

Enhanced Hypothalamic Glucose Sensing in Obesity: Alteration of Redox Signaling

Mitochondrial Reactive Oxygen Species Are Obligatory Signals for Glucose-Induced Insulin Secretion

Brain Glucagon-Like Peptide-1 Regulates Arterial Blood Flow, Heart Rate, and Insulin Sensitivity

mTOR Inhibition by Rapamycin Prevents β-Cell Adaptation to Hyperglycemia and Exacerbates the Metabolic State in Type 2 Diabetes

Insulin Internalizes GLUT2 in the Enterocytes of Healthy but Not Insulin-Resistant Mice

Fatty Acid Signaling in the Hypothalamus and the Neural Control of Insulin Secretion

Mitochondrial Reactive Oxygen Species Are Required for Hypothalamic Glucose Sensing

Psammomys Obesus, a Model for Environment-Gene Interactions in Type 2 Diabetes

Leptin Receptor−Deficient Obese Zucker Rats Reduce Their Food Intake in Response to a Systemic Supply of Calories From Glucose

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