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Christos S Mantzoros
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Journal Articles

Lorcaserin Administration Decreases Activation of Brain Centers in Response to Food Cues and These Emotion- and Salience-Related Changes Correlate With Weight Loss Effects: A 4-Week-Long Randomized, Placebo-Controlled, Double-Blind Clinical Trial

Olivia M. Farr, Jagriti Upadhyay, Anna Gavrieli, Michelle Camp, Nikolaos Spyrou, Harper Kaye, Hannah Mathew, Maria Vamvini, Anastasia Koniaris, Holly Kilim, Alexandra Srnka, Alexandra Migdal, Christos S. Mantzoros
Journal: Diabetes
Diabetes 2016;65(10):2943–2953
https://doi.org/10.2337/db16-0635
Published: 06 July 2016
View article titled, Lorcaserin Administration Decreases Activation of Brain Centers in Response to Food Cues and These Emotion- and Salience-Related Changes Correlate With Weight Loss Effects: A 4-Week-Long Randomized, Placebo-Controlled, Double-Blind Clinical Trial
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Includes: Supplementary data
Journal Articles

Identification and Saturable Nature of Signaling Pathways Induced by Metreleptin in Humans: Comparative Evaluation of In Vivo, Ex Vivo, and In Vitro Administration

Hyun-Seuk Moon, Joo Young Huh, Fadime Dincer, Benjamin E. Schneider, Per-Olof Hasselgren, Christos S. Mantzoros
Journal: Diabetes
Diabetes 2015;64(3):828–839
https://doi.org/10.2337/db14-0625
Published: 23 September 2014
View article titled, Identification and Saturable Nature of Signaling Pathways Induced by Metreleptin in Humans: Comparative Evaluation of In Vivo, Ex Vivo, and In Vitro Administration
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Journal Articles

Efficacy of Metreleptin in Obese Patients With Type 2 Diabetes: Cellular and Molecular Pathways Underlying Leptin Tolerance

Hyun-Seuk Moon, Giuseppe Matarese, Aoife M. Brennan, John P. Chamberland, Xiaowen Liu, Christina G. Fiorenza, Geetha H. Mylvaganam, Luisa Abanni, Fortunata Carbone, Catherine J. Williams, Alex M. De Paoli, Benjamin E. Schneider, Christos S. Mantzoros
Journal: Diabetes
Diabetes 2011;60(6):1647–1656
https://doi.org/10.2337/db10-1791
Published: 21 May 2011
View article titled, Efficacy of Metreleptin in Obese Patients With Type 2 Diabetes: Cellular and Molecular Pathways Underlying Leptin Tolerance
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Includes: Supplementary data
Journal Articles

Leptin and Soluble Leptin Receptor Levels in Plasma and Risk of Type 2 Diabetes in U.S. Women: A Prospective Study

Qi Sun, Rob M. van Dam, James B. Meigs, Oscar H. Franco, Christos S. Mantzoros, Frank B. Hu
Journal: Diabetes
Diabetes 2010;59(3):611–618
https://doi.org/10.2337/db09-1343
Published: 03 December 2009
View article titled, Leptin and Soluble Leptin Receptor Levels in Plasma and Risk of Type 2 Diabetes in U.S. Women: <subtitle>A Prospective Study</subtitle>
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Journal Articles

Adiponectin Genetic Variability, Plasma Adiponectin, and Cardiovascular Risk in Patients With Type 2 Diabetes

Lu Qi, Alessandro Doria, JoAnn E. Manson, James B. Meigs, David Hunter, Christos S. Mantzoros, Frank B. Hu
Journal: Diabetes
Diabetes 2006;55(5):1512–1516
https://doi.org/10.2337/db05-1520
Published: 01 May 2006
View article titled, Adiponectin Genetic Variability, Plasma Adiponectin, and Cardiovascular Risk in Patients With Type 2 Diabetes
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Journal Articles

Ciliary Neurotrophic FactorAx15 Alters Energy Homeostasis, Decreases Body Weight, and Improves Metabolic Control in Diet-Induced Obese and UCP1-DTA Mice

Susann Blüher, Stergios Moschos, John Bullen, Jr., Efi Kokkotou, Eleftheria Maratos-Flier, Stanley J. Wiegand, Mark W. Sleeman, Christos S. Mantzoros
Journal: Diabetes
Diabetes 2004;53(11):2787–2796
https://doi.org/10.2337/diabetes.53.11.2787
Published: 01 November 2004
View article titled, Ciliary Neurotrophic Factor<sub>Ax15</sub> Alters Energy Homeostasis, Decreases Body Weight, and Improves Metabolic Control in Diet-Induced Obese and UCP1-DTA Mice
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Includes: Supplementary data
Journal Articles

Responsiveness to Peripherally Administered Melanocortins in Lean and Obese Mice

Susann Blüher, Mary Ziotopoulou, John W. Bullen, Jr, Stergios J. Moschos, Linda Ungsunan, Efi Kokkotou, Eleftheria Maratos-Flier, Christos S. Mantzoros
Journal: Diabetes
Diabetes 2004;53(1):82–90
https://doi.org/10.2337/diabetes.53.1.82
Published: 01 January 2004
View article titled, Responsiveness to Peripherally Administered Melanocortins in Lean and Obese Mice
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Journal Articles

Regulation of Circulating Soluble Leptin Receptor Levels By Gender, Adiposity, Sex Steroids, and Leptin : Observational and Interventional Studies in Humans

Jean L. Chan, Susann Blüher, Nikos Yiannakouris, Marc A. Suchard, Jurgen Kratzsch, Christos S. Mantzoros
Journal: Diabetes
Diabetes 2002;51(7):2105–2112
https://doi.org/10.2337/diabetes.51.7.2105
Published: 01 July 2002
View article titled, Regulation of Circulating Soluble Leptin Receptor Levels By Gender, Adiposity, Sex Steroids, and Leptin : <subtitle>Observational and Interventional Studies in Humans </subtitle>
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Journal Articles

Effects of Acute and Chronic Administration of the Melanocortin Agonist MTII in Mice With Diet-Induced Obesity

Dominique D. Pierroz, Mary Ziotopoulou, Linda Ungsunan, Stergios Moschos, Jeffrey S. Flier, Christos S. Mantzoros
Journal: Diabetes
Diabetes 2002;51(5):1337–1345
https://doi.org/10.2337/diabetes.51.5.1337
Published: 01 May 2002
View article titled, Effects of Acute and Chronic Administration of the Melanocortin Agonist MTII in Mice With Diet-Induced Obesity
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Journal Articles

Severe Leptin Resistance in Brown Fat-Deficient Uncoupling Protein Promoter-Driven Diphtheria Toxin A Mice Despite Suppression of Hypothalamic Neuropeptide Y and Circulating Corticosterone Concentrations

Christos S Mantzoros, Robert C Frederich, Daqing Qu, Bradford B Lowell, Eleftheria Maratos-Flier, Jeffrey S Flier
Journal: Diabetes
Diabetes 1998;47(2):230–238
https://doi.org/10.2337/diab.47.2.230
Published: 01 February 1998
View article titled, Severe Leptin Resistance in Brown Fat-Deficient Uncoupling Protein Promoter-Driven Diphtheria Toxin A Mice Despite Suppression of Hypothalamic Neuropeptide Y and Circulating Corticosterone Concentrations
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Journal Articles

Activation of β3 Adrenergic Receptors Suppresses Leptin Expression and Mediates a Leptin-Independent Inhibition of Food Intake in Mice

Christos S Mantzoros, Robert C Frederich, Jeffrey S Flier, Daqing Qu, Vedrana S Susulic, Bradford B Lowell, Eleftheria Maratos-Flier
Journal: Diabetes
Diabetes 1996;45(7):909–914
https://doi.org/10.2337/diab.45.7.909
Published: 01 July 1996
View article titled, Activation of β<sub>3</sub> Adrenergic Receptors Suppresses Leptin Expression and Mediates a Leptin-Independent Inhibition of Food Intake in Mice
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