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Journal Articles

Inhibition of Pyruvate Dehydrogenase Kinase 2 Protects Against Hepatic Steatosis Through Modulation of Tricarboxylic Acid Cycle Anaplerosis and Ketogenesis

Younghoon Go, Ji Yun Jeong, Nam Ho Jeoung, Jae-Han Jeon, Bo-Yoon Park, Hyeon-Ji Kang, Chae-Myeong Ha, Young-Keun Choi, Sun Joo Lee, Hye Jin Ham, Byung-Gyu Kim, Keun-Gyu Park, So Young Park, Chul-Ho Lee, Cheol Soo Choi, Tae-Sik Park, W.N. Paul Lee, Robert A. Harris, In-Kyu Lee
Journal: Diabetes
Diabetes 2016;65(10):2876–2887
DOI: https://doi.org/10.2337/db16-0223
Published: 06 July 2016
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Includes: Supplementary data
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O-GlcNAcylation of Orphan Nuclear Receptor Estrogen-Related Receptor γ Promotes Hepatic Gluconeogenesis

Jagannath Misra, Don-Kyu Kim, Yoon Seok Jung, Han Byeol Kim, Yong-Hoon Kim, Eun-Kyung Yoo, Byung Gyu Kim, Sunghoon Kim, In-Kyu Lee, Robert A. Harris, Jeong-Sun Kim, Chul-Ho Lee, Jin Won Cho, Hueng-Sik Choi
Journal: Diabetes
Diabetes 2016;65(10):2835–2848
DOI: https://doi.org/10.2337/db15-1523
Published: 22 June 2016
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Glucose-6-Phosphate Dehydrogenase Deficiency Improves Insulin Resistance With Reduced Adipose Tissue Inflammation in Obesity

Mira Ham, Sung Sik Choe, Kyung Cheul Shin, Goun Choi, Ji-Won Kim, Jung-Ran Noh, Yong-Hoon Kim, Je-won Ryu, Kun-Ho Yoon, Chul-Ho Lee, Jae Bum Kim
Journal: Diabetes
Diabetes 2016;65(9):2624–2638
DOI: https://doi.org/10.2337/db16-0060
Published: 09 June 2016
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Includes: Supplementary data
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Insulin-Inducible SMILE Inhibits Hepatic Gluconeogenesis

Ji-Min Lee, Woo-Young Seo, Hye-Sook Han, Kyoung-Jin Oh, Yong-Soo Lee, Don-Kyu Kim, Seri Choi, Byeong Hun Choi, Robert A. Harris, Chul-Ho Lee, Seung-Hoi Koo, Hueng-Sik Choi
Journal: Diabetes
Diabetes 2016;65(1):62–73
DOI: https://doi.org/10.2337/db15-0249
Published: 04 September 2015
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Includes: Supplementary data
Journal Articles

SIK2 Is Critical in the Regulation of Lipid Homeostasis and Adipogenesis In Vivo

Jinyoung Park, Young-Sil Yoon, Hye-Sook Han, Yong-Hoon Kim, Yoshihiro Ogawa, Keun-Gyu Park, Chul-Ho Lee, Seong-Tae Kim, Seung-Hoi Koo
Journal: Diabetes
Diabetes 2014;63(11):3659–3673
DOI: https://doi.org/10.2337/db13-1423
Published: 13 October 2014
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Includes: Supplementary data
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Inverse Agonist of Nuclear Receptor ERRγ Mediates Antidiabetic Effect Through Inhibition of Hepatic Gluconeogenesis

Don-Kyu Kim, Gil-Tae Gang, Dongryeol Ryu, Minseob Koh, Yo-Na Kim, Su Sung Kim, Jinyoung Park, Yong-Hoon Kim, Taebo Sim, In-Kyu Lee, Cheol Soo Choi, Seung Bum Park, Chul-Ho Lee, Seung-Hoi Koo, Hueng-Sik Choi
Journal: Diabetes
Diabetes 2013;62(9):3093–3102
DOI: https://doi.org/10.2337/db12-0946
Published: 15 August 2013
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Includes: Supplementary data
Journal Articles

Metformin Inhibits Growth Hormone–Mediated Hepatic PDK4 Gene Expression Through Induction of Orphan Nuclear Receptor Small Heterodimer Partner

Yong Deuk Kim, Yong-Hoon Kim, Surendar Tadi, Ji Hoon Yu, Yong-Hyeon Yim, Nam Ho Jeoung, Minho Shong, Lothar Hennighausen, Robert A. Harris, In-Kyu Lee, Chul-Ho Lee, Hueng-Sik Choi
Journal: Diabetes
Diabetes 2012;61(10):2484–2494
DOI: https://doi.org/10.2337/db11-1665
Published: 13 September 2012
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Includes: Supplementary data
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Metformin Inhibits Hepatic Gluconeogenesis Through AMP-Activated Protein Kinase–Dependent Regulation of the Orphan Nuclear Receptor SHP

Yong Deuk Kim, Keun-Gyu Park, Yong-Soo Lee, Yun-Yong Park, Don-Kyu Kim, Balachandar Nedumaran, Won Gu Jang, Won-Jea Cho, Joohun Ha, In-Kyu Lee, Chul-Ho Lee, Hueng-Sik Choi
Journal: Diabetes
Diabetes 2008;57(2):306–314
DOI: https://doi.org/10.2337/db07-0381
Published: 01 February 2008
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Includes: Supplementary data
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Novel Leptin Receptor Mutation in NOD/LtJ Mice Suppresses Type 1 Diabetes Progression: II. Immunologic Analysis

Chul-Ho Lee, Yi-Guang Chen, Jing Chen, Peter C. Reifsnyder, David V. Serreze, Michael Clare-Salzler, Michelle Rodriguez, Clive Wasserfall, Mark A. Atkinson, Edward H. Leiter
Journal: Diabetes
Diabetes 2006;55(1):171–178
DOI: https://doi.org/10.2337/diabetes.55.01.06.db05-1129
Published: 01 January 2006
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Journal Articles

Mouse Models and the Genetics of Diabetes: Is There Evidence for Genetic Overlap Between Type 1 and Type 2 Diabetes?

Edward H. Leiter, Chul-Ho Lee
Journal: Diabetes
Diabetes 2005;54(suppl_2):S151–S158
DOI: https://doi.org/10.2337/diabetes.54.suppl_2.S151
Published: 01 December 2005
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Journal Articles

Novel Leptin Receptor Mutation in NOD/LtJ Mice Suppresses Type 1 Diabetes Progression: I. Pathophysiological Analysis

Chul-Ho Lee, Peter C. Reifsnyder, Jürgen K. Naggert, Clive Wasserfall, Mark A. Atkinson, Jing Chen, Edward H. Leiter
Journal: Diabetes
Diabetes 2005;54(9):2525–2532
DOI: https://doi.org/10.2337/diabetes.54.9.2525
Published: 01 September 2005
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