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Journal Articles

The Longitudinal Effect of Diabetes-Associated Variation in TCF7L2 on Islet Function in Humans

Maya Zeini, Marcello C. Laurenti, Aoife M. Egan, Kalpana Muthusamy, Anisha Ramar, Emma Vella, Kent R. Bailey, Claudio Cobelli, Chiara Dalla Man, Adrian Vella

Diabetes 2024;73(9):1440–1446

https://doi.org/10.2337/db24-0192

Published: 13 June 2024

View article titled, The Longitudinal Effect of Diabetes-Associated Variation in <em>TCF7L2</em> on Islet Function in Humans

Meeting Abstracts

337-OR: Hyperglycemia Lowers Lactate Clearance during Exercise in Type 1 Diabetes

DAVIDE ROMERES, YOGESH YADAV, FNU RUCHI, RICKEY CARTER, CLAUDIO COBELLI, RITA BASU, ANANDA BASU

Diabetes 2023;72(Supplement_1):337-OR

https://doi.org/10.2337/db23-337-OR

Published: 20 June 2023

View article titled, 337-OR: Hyperglycemia Lowers Lactate Clearance during Exercise in Type 1 Diabetes

Meeting Abstracts

1564-P: Impaired Insulin Secretion Increases Glucagon Action on the Liver

ALESSIO TONELLO, MARCELLO C. LAURENTI, CLAUDIO COBELLI, ADRIAN VELLA, CHIARA DALLA MAN

Diabetes 2023;72(Supplement_1):1564-P

https://doi.org/10.2337/db23-1564-P

Published: 20 June 2023

View article titled, 1564-P: Impaired Insulin Secretion Increases Glucagon Action on the Liver

Meeting Abstracts

585-P: Lactate Kinetics in Type 1 Diabetes—A 1-13C Lactate Study

DAVIDE ROMERES, FNU RUCHI, YOGESH YADAV, CLAUDIO COBELLI, ANANDA BASU, RITA BASU

Diabetes 2023;72(Supplement_1):585-P

https://doi.org/10.2337/db23-585-P

Published: 20 June 2023

View article titled, 585-P: Lactate Kinetics in Type 1 Diabetes—A 1-13C Lactate Study

Meeting Abstracts

1646-P: The Effect of Glucagon-Like Peptide-1 Receptor Blockade and Acute Insulin Resistance on Islet Function and Glucose Metabolism in People without Diabetes

MAYA ZEINI, RAHELE A. FARAHANI, ANDREW A. WELCH, MARCELLO C. LAURENTI, CLAUDIO COBELLI, CHIARA DALLA MAN, AOIFE M. EGAN, ADRIAN VELLA

Diabetes 2023;72(Supplement_1):1646-P

https://doi.org/10.2337/db23-1646-P

Published: 20 June 2023

View article titled, 1646-P: The Effect of Glucagon-Like Peptide-1 Receptor Blockade and Acute Insulin Resistance on Islet Function and Glucose Metabolism in People without Diabetes

Meeting Abstracts

1645-P: Diabetes-Associated Variation in TCF7L2 Is Associated with a Longitudinal Decline in Glucose Tolerance Accompanied by Impaired Suppression of Postprandial Glucagon Secretion

MAYA ZEINI, KALPANA MUTHUSAMY, AOIFE M. EGAN, MARCELLO C. LAURENTI, CLAUDIO COBELLI, CHIARA DALLA MAN, ADRIAN VELLA

Diabetes 2023;72(Supplement_1):1645-P

https://doi.org/10.2337/db23-1645-P

Published: 20 June 2023

View article titled, 1645-P: Diabetes-Associated Variation in TCF7L2 Is Associated with a Longitudinal Decline in Glucose Tolerance Accompanied by Impaired Suppression of Postprandial Glucagon Secretion

Meeting Abstracts

36-OR: The Effect of Glucagon-Like Peptide-1 Receptor Blockade on the ß-Cell Response to Glucagon Bolus in People With and Without Type 2 Diabetes

AOIFE M. EGAN, MAYA ZEINI, ANDREW A. WELCH, RAHELE A. FARAHANI, MARCELLO C. LAURENTI, CLAUDIO COBELLI, CHIARA DALLA MAN, ADRIAN VELLA

Diabetes 2023;72(Supplement_1):36-OR

https://doi.org/10.2337/db23-36-OR

Published: 20 June 2023

View article titled, 36-OR: The Effect of Glucagon-Like Peptide-1 Receptor Blockade on the ß-Cell Response to Glucagon Bolus in People With and Without Type 2 Diabetes

Meeting Abstracts

1547-P: The Differential Effect of Glucagon-Like Peptide-1 Receptor Blockade on Glucose Metabolism in People With and Without Type 2 Diabetes

ANDREW A. WELCH, RAHELE A. FARAHANI, MAYA ZEINI, AOIFE M. EGAN, MARCELLO C. LAURENTI, CLAUDIO COBELLI, CHIARA DALLA MAN, ADRIAN VELLA

Diabetes 2023;72(Supplement_1):1547-P

https://doi.org/10.2337/db23-1547-P

Published: 20 June 2023

View article titled, 1547-P: The Differential Effect of Glucagon-Like Peptide-1 Receptor Blockade on Glucose Metabolism in People With and Without Type 2 Diabetes

Journal Articles

The Effect of Glucagon-Like Peptide 1 Receptor Blockade on Glucagon-Induced Stimulation of Insulin Secretion

Rahele A. Farahani, Aoife M. Egan, Andrew A. Welch, Marcello C. Laurenti, Claudio Cobelli, Chiara Dalla Man, Adrian Vella

Diabetes 2023;72(4):449–454

https://doi.org/10.2337/db22-0709

Published: 23 December 2022

View article titled, The Effect of Glucagon-Like Peptide 1 Receptor Blockade on Glucagon-Induced Stimulation of Insulin Secretion

Journal Articles

Impaired Diurnal Pattern of Meal Tolerance and Insulin Sensitivity in Type 2 Diabetes: Implications for Therapy

Yogesh Yadav, Davide Romeres, Claudio Cobelli, Chiara Dalla Man, Rickey Carter, Ananda Basu, Rita Basu

Diabetes 2023;72(2):223–232

https://doi.org/10.2337/db22-0238

Published: 08 November 2022

View article titled, Impaired Diurnal Pattern of Meal Tolerance and Insulin Sensitivity in Type 2 Diabetes: Implications for Therapy

Meeting Abstracts

1325-P: Modulation of Overnight Free Fatty Acid and Glucose Concentrations and Their Effect on Postprandial Islet Function and Glucose Metabolism

ANDREW A. WELCH, DANIEL SCHEMBRI WISMAYER, AOIFE M. EGAN, RAHELE A. FARAHANI, MARCELLO C. LAURENTI, CLAUDIO COBELLI, CHIARA DALLA MAN, ADRIAN VELLA

Diabetes 2022;71(Supplement_1):1325-P

https://doi.org/10.2337/db22-1325-P

Published: 01 June 2022

View article titled, 1325-P: Modulation of Overnight Free Fatty Acid and Glucose Concentrations and Their Effect on Postprandial Islet Function and Glucose Metabolism

Meeting Abstracts

358-OR: The Effect of Glucagon-Like Peptide-1 Receptor Blockade on Glucagon-Induced Stimulation of Insulin Secretion

RAHELE A. FARAHANI, AOIFE M. EGAN, ANDREW A. WELCH, MARCELLO C. LAURENTI, CLAUDIO COBELLI, CHIARA DALLA MAN, ADRIAN VELLA

Diabetes 2022;71(Supplement_1):358-OR

https://doi.org/10.2337/db22-358-OR

Published: 01 June 2022

View article titled, 358-OR: The Effect of Glucagon-Like Peptide-1 Receptor Blockade on Glucagon-Induced Stimulation of Insulin Secretion

Meeting Abstracts

218-LB: Remission of Type 2 Diabetes after Weight Loss in "Normal" Weight People—The ReTUNE Study

ROY TAYLOR, KEATON M. IRVINE, ALISON C. BARNES, TARA L. KELLY, LUCY G. CLARK, KIEREN G. HOLLINGSWORTH, AHMAD AL-MRABEH, RURY R. HOLMAN, DAVIDE ROMERES, CLAUDIO COBELLI

Diabetes 2022;71(Supplement_1):218-LB

https://doi.org/10.2337/db22-218-LB

Published: 01 June 2022

View article titled, 218-LB: Remission of Type 2 Diabetes after Weight Loss in "Normal" Weight People—The ReTUNE Study

Meeting Abstracts

1377-P: Pramlintide Lowers Postprandial Glucagon Concentrations by Inhibiting Glucagon Secretion without Altering Clearance in Type 1 Diabetes: A [13C15N]-Glucagon Study

FNU RUCHI, DAVIDE ROMERES, MICHELE SCHIAVON, SANTOSH RENUSE, AKHILESH PANDEY, CHIARA DALLA MAN, CLAUDIO COBELLI, RITA BASU, ANANDA BASU

Diabetes 2022;71(Supplement_1):1377-P

https://doi.org/10.2337/db22-1377-P

Published: 01 June 2022

View article titled, 1377-P: Pramlintide Lowers Postprandial Glucagon Concentrations by Inhibiting Glucagon Secretion without Altering Clearance in Type 1 Diabetes: A [13C15N]-Glucagon Study

Meeting Abstracts

1376-P: Comparison of a-Cell Response to Intravenous or Oral Glucose in Nondiabetic Humans

MARCELLO C. LAURENTI, ARMANDO MANDUCA, CLAUDIO COBELLI, CHIARA DALLA MAN, ADRIAN VELLA

Diabetes 2022;71(Supplement_1):1376-P

https://doi.org/10.2337/db22-1376-P

Published: 01 June 2022

View article titled, 1376-P: Comparison of a-Cell Response to Intravenous or Oral Glucose in Nondiabetic Humans

Meeting Abstracts

206-LB: Indian Americans as Compared with Indians Exhibit Increased Beta-Cell Responsivity and Insulin Clearance in Absence of Changes in Insulin Sensitivity

VEDAVATI PURANDARE, ALFONSO GALDERISI, MARIANGELA MAERTINO, ANANDA BASU, CLAUDIO COBELLI, AMBIKA GOPALAKRISHNAN UNNIKRISHNAN, RITA BASU

Diabetes 2021;70(Supplement_1):206-LB

https://doi.org/10.2337/db21-206-LB

Published: 01 June 2021

View article titled, 206-LB: Indian Americans as Compared with Indians Exhibit Increased Beta-Cell Responsivity and Insulin Clearance in Absence of Changes in Insulin Sensitivity

Meeting Abstracts

259-OR: The Effect of Impaired Glucagon Suppression on Endogenous Glucose Production Is Independent of Insulin Action

MARCELLO C. LAURENTI, AOIFE M. EGAN, DANIEL SCHEMBRI WISMAYER, CLAUDIO COBELLI, CHIARA DALLA MAN, ADRIAN VELLA

Diabetes 2021;70(Supplement_1):259-OR

https://doi.org/10.2337/db21-259-OR

Published: 01 June 2021

View article titled, 259-OR: The Effect of Impaired Glucagon Suppression on Endogenous Glucose Production Is Independent of Insulin Action

Meeting Abstracts

262-OR: Postprandial Glucagon Metabolism in Type 1 Diabetes

FNU RUCHI, YOGESH R. YADAV, MICHELE SCHIAVON, ALEXANDRA WEAVER, CLAUDIO COBELLI, CHIARA DALLA MAN, RITA BASU, ANANDA BASU

Diabetes 2021;70(Supplement_1):262-OR

https://doi.org/10.2337/db21-262-OR

Published: 01 June 2021

View article titled, 262-OR: Postprandial Glucagon Metabolism in Type 1 Diabetes

Meeting Abstracts

264-OR: Glucagon Kinetics: Model from First-in-Humans with 13C15N Glucagon

MICHELE SCHIAVON, FNU RUCHI, YOGESH R. YADAV, RITA BASU, CLAUDIO COBELLI, CHIARA DALLA MAN, ANANDA BASU

Diabetes 2021;70(Supplement_1):264-OR

https://doi.org/10.2337/db21-264-OR

Published: 01 June 2021

View article titled, 264-OR: Glucagon Kinetics: Model from First-in-Humans with 13C15N Glucagon

Meeting Abstracts

263-OR: Higher Glycemic Threshold for Glucagon Suppression in Impaired Fasting Glucose and Impaired Glucose Tolerance

JACOB D. KOHLENBERG, MARCELLO C. LAURENTI, AOIFE M. EGAN, CLAUDIO COBELLI, CHIARA DALLA MAN, ADRIAN VELLA

Diabetes 2021;70(Supplement_1):263-OR

https://doi.org/10.2337/db21-263-OR

Published: 01 June 2021

View article titled, 263-OR: Higher Glycemic Threshold for Glucagon Suppression in Impaired Fasting Glucose and Impaired Glucose Tolerance

NARROW

The Longitudinal Effect of Diabetes-Associated Variation in TCF7L2 on Islet Function in Humans

337-OR: Hyperglycemia Lowers Lactate Clearance during Exercise in Type 1 Diabetes

1564-P: Impaired Insulin Secretion Increases Glucagon Action on the Liver

585-P: Lactate Kinetics in Type 1 Diabetes—A 1-13C Lactate Study

1646-P: The Effect of Glucagon-Like Peptide-1 Receptor Blockade and Acute Insulin Resistance on Islet Function and Glucose Metabolism in People without Diabetes

1645-P: Diabetes-Associated Variation in TCF7L2 Is Associated with a Longitudinal Decline in Glucose Tolerance Accompanied by Impaired Suppression of Postprandial Glucagon Secretion

36-OR: The Effect of Glucagon-Like Peptide-1 Receptor Blockade on the ß-Cell Response to Glucagon Bolus in People With and Without Type 2 Diabetes

1547-P: The Differential Effect of Glucagon-Like Peptide-1 Receptor Blockade on Glucose Metabolism in People With and Without Type 2 Diabetes

The Effect of Glucagon-Like Peptide 1 Receptor Blockade on Glucagon-Induced Stimulation of Insulin Secretion

Impaired Diurnal Pattern of Meal Tolerance and Insulin Sensitivity in Type 2 Diabetes: Implications for Therapy

1325-P: Modulation of Overnight Free Fatty Acid and Glucose Concentrations and Their Effect on Postprandial Islet Function and Glucose Metabolism

358-OR: The Effect of Glucagon-Like Peptide-1 Receptor Blockade on Glucagon-Induced Stimulation of Insulin Secretion

218-LB: Remission of Type 2 Diabetes after Weight Loss in "Normal" Weight People—The ReTUNE Study

1377-P: Pramlintide Lowers Postprandial Glucagon Concentrations by Inhibiting Glucagon Secretion without Altering Clearance in Type 1 Diabetes: A [13C15N]-Glucagon Study

1376-P: Comparison of a-Cell Response to Intravenous or Oral Glucose in Nondiabetic Humans

206-LB: Indian Americans as Compared with Indians Exhibit Increased Beta-Cell Responsivity and Insulin Clearance in Absence of Changes in Insulin Sensitivity

259-OR: The Effect of Impaired Glucagon Suppression on Endogenous Glucose Production Is Independent of Insulin Action

262-OR: Postprandial Glucagon Metabolism in Type 1 Diabetes

264-OR: Glucagon Kinetics: Model from First-in-Humans with 13C15N Glucagon

263-OR: Higher Glycemic Threshold for Glucagon Suppression in Impaired Fasting Glucose and Impaired Glucose Tolerance

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