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Journal Articles

Monogenic Diabetes and Integrated Stress Response Genes Display Altered Gene Expression in Type 1 Diabetes

Helmut Hiller, Dawn E. Beachy, Joseph J. Lebowitz, Stefanie Engler, Justin R. Mason, Douglas R. Miller, Irina Kusmarteva, Laura M. Jacobsen, Amanda L. Posgai, Habibeh Khoshbouei, Richard A. Oram, Desmond A. Schatz, Andrew T. Hattersley, Bernd Bodenmiller, Mark A. Atkinson, Harry S. Nick, Clive H. Wasserfall

Diabetes 2021;70(8):1885–1897

https://doi.org/10.2337/db21-0070

Published: 25 May 2021

View article titled, Monogenic Diabetes and Integrated Stress Response Genes Display Altered Gene Expression in Type 1 Diabetes

Journal Articles

Low-Dose ATG/GCSF in Established Type 1 Diabetes: A Five-Year Follow-up Report

Andrea Lin, Jasmine A. Mack, Brittany Bruggeman, Laura M. Jacobsen, Amanda L. Posgai, Clive H. Wasserfall, Todd M. Brusko, Mark A. Atkinson, Stephen E. Gitelman, Peter A. Gottlieb, Matthew J. Gurka, Clayton E. Mathews, Desmond A. Schatz, Michael J. Haller

Diabetes 2021;70(5):1123–1129

https://doi.org/10.2337/db20-1103

Published: 25 February 2021

View article titled, Low-Dose ATG/GCSF in Established Type 1 Diabetes: A Five-Year Follow-up Report

Journal Articles

Exocrine Pancreatic Enzymes Are a Serological Biomarker for Type 1 Diabetes Staging and Pancreas Size

James J. Ross, Clive H. Wasserfall, Rhonda Bacher, Daniel J. Perry, Kieran McGrail, Amanda L. Posgai, Xiaoru Dong, Andrew Muir, Xia Li, Martha Campbell-Thompson, Todd M. Brusko, Desmond A. Schatz, Michael J. Haller, Mark A. Atkinson

Diabetes 2021;70(4):944–954

https://doi.org/10.2337/db20-0995

Published: 13 January 2021

View article titled, Exocrine Pancreatic Enzymes Are a Serological Biomarker for Type 1 Diabetes Staging and Pancreas Size

Journal Articles

Genetic Composition and Autoantibody Titers Model the Probability of Detecting C-Peptide Following Type 1 Diabetes Diagnosis

MacKenzie D. Williams, Rhonda Bacher, Daniel J. Perry, C. Ramsey Grace, Kieran M. McGrail, Amanda L. Posgai, Andrew Muir, Srikar Chamala, Michael J. Haller, Desmond A. Schatz, Todd M. Brusko, Mark A. Atkinson, Clive H. Wasserfall

Diabetes 2021;70(4):932–943

https://doi.org/10.2337/db20-0937

Published: 08 January 2021

View article titled, Genetic Composition and Autoantibody Titers Model the Probability of Detecting C-Peptide Following Type 1 Diabetes Diagnosis

Journal Articles

Insulin-Like Growth Factor Dysregulation Both Preceding and Following Type 1 Diabetes Diagnosis

Melanie R. Shapiro, Clive H. Wasserfall, Sean M. McGrail, Amanda L. Posgai, Rhonda Bacher, Andrew Muir, Michael J. Haller, Desmond A. Schatz, Johnna D. Wesley, Matthias von Herrath, William A. Hagopian, Cate Speake, Mark A. Atkinson, Todd M. Brusko

Diabetes 2020;69(3):413–423

https://doi.org/10.2337/db19-0942

Published: 11 December 2020

View article titled, Insulin-Like Growth Factor Dysregulation Both Preceding and Following Type 1 Diabetes Diagnosis

Includes: Supplementary data

Journal Articles

Temporal Analysis of Amylase Expression in Control, Autoantibody-Positive, and Type 1 Diabetes Pancreatic Tissues

Irina Kusmartseva, Maria Beery, Helmut Hiller, Myriam Padilla, Stephen Selman, Amanda Posgai, Harry S. Nick, Martha Campbell-Thompson, Desmond A. Schatz, Michael J. Haller, Clive H. Wasserfall, Mark A. Atkinson

Diabetes 2020;69(1):60–66

https://doi.org/10.2337/db19-0554

Published: 09 October 2019

View article titled, Temporal Analysis of Amylase Expression in Control, Autoantibody-Positive, and Type 1 Diabetes Pancreatic Tissues

Includes: Supplementary data

Journal Articles

Islet-Derived eATP Fuels Autoreactive CD8⁺ T Cells and Facilitates the Onset of Type 1 Diabetes

Diabetes 2018;67(10):2038–2053

https://doi.org/10.2337/db17-1227

Published: 31 July 2018

View article titled, Islet-Derived eATP Fuels Autoreactive CD8+ T Cells and Facilitates the Onset of Type 1 Diabetes

Journal Articles

Antithymocyte Globulin Plus G-CSF Combination Therapy Leads to Sustained Immunomodulatory and Metabolic Effects in a Subset of Responders With Established Type 1 Diabetes

Michael J. Haller, Stephen E. Gitelman, Peter A. Gottlieb, Aaron W. Michels, Daniel J. Perry, Andrew R. Schultz, Maigan A. Hulme, Jonathan J. Shuster, Baiming Zou, Clive H. Wasserfall, Amanda L. Posgai, Clayton E. Mathews, Todd M. Brusko, Mark A. Atkinson, Desmond A. Schatz

Diabetes 2016;65(12):3765–3775

https://doi.org/10.2337/db16-0823

Published: 26 September 2016

View article titled, Antithymocyte Globulin Plus G-CSF Combination Therapy Leads to Sustained Immunomodulatory and Metabolic Effects in a Subset of Responders With Established Type 1 Diabetes

Includes: Supplementary data

Journal Articles

A Preclinical Consortium Approach for Assessing the Efficacy of Combined Anti-CD3 Plus IL-1 Blockade in Reversing New-Onset Autoimmune Diabetes in NOD Mice

Ronald G. Gill, Philippe P. Pagni, Tinalyn Kupfer, Clive H. Wasserfall, Songyan Deng, Amanda Posgai, Yulia Manenkova, Amira Bel Hani, Laura Straub, Philip Bernstein, Mark A. Atkinson, Kevan C. Herold, Matthias von Herrath, Teodora Staeva, Mario R. Ehlers, Gerald T. Nepom

Diabetes 2016;65(5):1310–1316

https://doi.org/10.2337/db15-0492

Published: 31 December 2015

View article titled, A Preclinical Consortium Approach for Assessing the Efficacy of Combined Anti-CD3 Plus IL-1 Blockade in Reversing New-Onset Autoimmune Diabetes in NOD Mice

Includes: Supplementary data

Journal Articles

Interleukin-10⁺ Regulatory B Cells Arise Within Antigen-Experienced CD40⁺ B Cells to Maintain Tolerance to Islet Autoantigens

Sonja Kleffel, Andrea Vergani, Sara Tezza, Moufida Ben Nasr, Monika A. Niewczas, Susan Wong, Roberto Bassi, Francesca D’Addio, Tobias Schatton, Reza Abdi, Mark Atkinson, Mohamed H. Sayegh, Li Wen, Clive H. Wasserfall, Kevin C. O’Connor, Paolo Fiorina

Diabetes 2015;64(1):158–171

https://doi.org/10.2337/db13-1639

Published: 03 September 2014

View article titled, Interleukin-10+ Regulatory B Cells Arise Within Antigen-Experienced CD40+ B Cells to Maintain Tolerance to Islet Autoantigens

Includes: Supplementary data

Journal Articles

Oral Delivery of Glutamic Acid Decarboxylase (GAD)-65 and IL10 by Lactococcus lactis Reverses Diabetes in Recent-Onset NOD Mice

Sofie Robert, Conny Gysemans, Tatiana Takiishi, Hannelie Korf, Isabella Spagnuolo, Guido Sebastiani, Karolien Van Huynegem, Lothar Steidler, Silvia Caluwaerts, Pieter Demetter, Clive H. Wasserfall, Mark A. Atkinson, Francesco Dotta, Pieter Rottiers, Tom L. Van Belle, Chantal Mathieu

Diabetes 2014;63(8):2876–2887

https://doi.org/10.2337/db13-1236

Published: 17 July 2014

View article titled, Oral Delivery of Glutamic Acid Decarboxylase (GAD)-65 and IL10 by Lactococcus lactis Reverses Diabetes in Recent-Onset NOD Mice

Includes: Supplementary data

Journal Articles

Central Role for Interleukin-2 in Type 1 Diabetes

Maigan A. Hulme, Clive H. Wasserfall, Mark A. Atkinson, Todd M. Brusko

Diabetes 2012;61(1):14–22

https://doi.org/10.2337/db11-1213

Published: 12 December 2011

View article titled, Central Role for Interleukin-2 in Type 1 Diabetes

Journal Articles

Immune Depletion With Cellular Mobilization Imparts Immunoregulation and Reverses Autoimmune Diabetes in Nonobese Diabetic Mice

Matthew J. Parker, Song Xue, John J. Alexander, Clive H. Wasserfall, Martha L. Campbell-Thompson, Manuela Battaglia, Silvia Gregori, Clayton E. Mathews, Sihong Song, Misty Troutt, Scott Eisenbeis, John Williams, Desmond A. Schatz, Michael J. Haller, Mark A. Atkinson

Diabetes 2009;58(10):2277–2284

https://doi.org/10.2337/db09-0557

Published: 23 July 2009

View article titled, Immune Depletion With Cellular Mobilization Imparts Immunoregulation and Reverses Autoimmune Diabetes in Nonobese Diabetic Mice

Includes: Supplementary data

Journal Articles

Cystic Fibrosis Transmembrane Conductance Regulator Deficiency Exacerbates Islet Cell Dysfunction After β-Cell Injury

Michael S. Stalvey, Christian Muller, Desmond A. Schatz, Clive H. Wasserfall, Martha L. Campbell-Thompson, Douglas W. Theriaque, Terence R. Flotte, Mark A. Atkinson

Diabetes 2006;55(7):1939–1945

https://doi.org/10.2337/db05-1647

Published: 01 July 2006

View article titled, Cystic Fibrosis Transmembrane Conductance Regulator Deficiency Exacerbates Islet Cell Dysfunction After β-Cell Injury

Journal Articles

Functional Defects and the Influence of Age on the Frequency of CD4⁺CD25⁺ T-Cells in Type 1 Diabetes

Todd M. Brusko, Clive H. Wasserfall, Michael J. Clare-Salzler, Desmond A. Schatz, Mark A. Atkinson

Diabetes 2005;54(5):1407–1414

https://doi.org/10.2337/diabetes.54.5.1407

Published: 01 May 2005

View article titled, Functional Defects and the Influence of Age on the Frequency of CD4+CD25+ T-Cells in Type 1 Diabetes

NARROW

Monogenic Diabetes and Integrated Stress Response Genes Display Altered Gene Expression in Type 1 Diabetes

Low-Dose ATG/GCSF in Established Type 1 Diabetes: A Five-Year Follow-up Report

Exocrine Pancreatic Enzymes Are a Serological Biomarker for Type 1 Diabetes Staging and Pancreas Size

Genetic Composition and Autoantibody Titers Model the Probability of Detecting C-Peptide Following Type 1 Diabetes Diagnosis

Insulin-Like Growth Factor Dysregulation Both Preceding and Following Type 1 Diabetes Diagnosis

Temporal Analysis of Amylase Expression in Control, Autoantibody-Positive, and Type 1 Diabetes Pancreatic Tissues

Islet-Derived eATP Fuels Autoreactive CD8⁺ T Cells and Facilitates the Onset of Type 1 Diabetes

Antithymocyte Globulin Plus G-CSF Combination Therapy Leads to Sustained Immunomodulatory and Metabolic Effects in a Subset of Responders With Established Type 1 Diabetes

A Preclinical Consortium Approach for Assessing the Efficacy of Combined Anti-CD3 Plus IL-1 Blockade in Reversing New-Onset Autoimmune Diabetes in NOD Mice

Interleukin-10⁺ Regulatory B Cells Arise Within Antigen-Experienced CD40⁺ B Cells to Maintain Tolerance to Islet Autoantigens

Oral Delivery of Glutamic Acid Decarboxylase (GAD)-65 and IL10 by Lactococcus lactis Reverses Diabetes in Recent-Onset NOD Mice

Central Role for Interleukin-2 in Type 1 Diabetes

Immune Depletion With Cellular Mobilization Imparts Immunoregulation and Reverses Autoimmune Diabetes in Nonobese Diabetic Mice

Cystic Fibrosis Transmembrane Conductance Regulator Deficiency Exacerbates Islet Cell Dysfunction After β-Cell Injury

Functional Defects and the Influence of Age on the Frequency of CD4⁺CD25⁺ T-Cells in Type 1 Diabetes

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