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Colin M. Dayan
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Journal Articles

Evidence for C-Peptide as a Validated Surrogate to Predict Clinical Benefits in Trials of Disease-Modifying Therapies for Type 1 Diabetes

Esther Latres, Carla J. Greenbaum, Maria L. Oyaski, Colin M. Dayan, Helen M. Colhoun, John M. Lachin, Jay S. Skyler, Michael R. Rickels, Simi T. Ahmed, Sanjoy Dutta, Kevan C. Herold, Marjana Marinac
Journal: Diabetes
Diabetes 2024;73(6):823–833
https://doi.org/10.2337/dbi23-0012
Published: 13 February 2024
View articletitled, Evidence for C-Peptide as a Validated Surrogate to Predict Clinical Benefits in Trials of Disease-Modifying Therapies for Type 1 Diabetes
Open the PDF for Evidence for C-Peptide as a Validated Surrogate to Predict Clinical Benefits in Trials of Disease-Modifying Therapies for Type 1 Diabetes in another window
Journal Articles

β-Cell–Specific CD8 T Cell Phenotype in Type 1 Diabetes Reflects Chronic Autoantigen Exposure

Ania Skowera, Kristin Ladell, James E. McLaren, Garry Dolton, Katherine K. Matthews, Emma Gostick, Deborah Kronenberg-Versteeg, Martin Eichmann, Robin R. Knight, Susanne Heck, Jake Powrie, Polly J. Bingley, Colin M. Dayan, John J. Miles, Andrew K. Sewell, David A. Price, Mark Peakman
Journal: Diabetes
Diabetes 2015;64(3):916–925
https://doi.org/10.2337/db14-0332
Published: 22 September 2014
View articletitled, β-Cell–Specific CD8 T Cell Phenotype in Type 1 Diabetes Reflects Chronic Autoantigen Exposure
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Includes: Supplementary data
Journal Articles

Circulating Preproinsulin Signal Peptide–Specific CD8 T Cells Restricted by the Susceptibility Molecule HLA-A24 Are Expanded at Onset of Type 1 Diabetes and Kill β-Cells

Deborah Kronenberg, Robin R. Knight, Megan Estorninho, Richard J. Ellis, Michel G. Kester, Arnoud de Ru, Martin Eichmann, Guo C. Huang, Jake Powrie, Colin M. Dayan, Ania Skowera, Peter A. van Veelen, Mark Peakman
Journal: Diabetes
Diabetes 2012;61(7):1752–1759
https://doi.org/10.2337/db11-1520
Published: 15 June 2012
View articletitled, Circulating Preproinsulin Signal Peptide–Specific CD8 T Cells Restricted by the Susceptibility Molecule HLA-A24 Are Expanded at Onset of Type 1 Diabetes and Kill β-Cells
Open the PDF for Circulating Preproinsulin Signal Peptide–Specific CD8 T Cells Restricted by the Susceptibility Molecule HLA-A24 Are Expanded at Onset of Type 1 Diabetes and Kill β-Cells in another window
Includes: Supplementary data
Journal Articles

Peripheral and Islet Interleukin-17 Pathway Activation Characterizes Human Autoimmune Diabetes and Promotes Cytokine-Mediated β-Cell Death

Sefina Arif, Fabrice Moore, Katherine Marks, Thomas Bouckenooghe, Colin M. Dayan, Raquel Planas, Marta Vives-Pi, Jake Powrie, Timothy Tree, Piero Marchetti, Guo Cai Huang, Esteban N. Gurzov, Ricardo Pujol-Borrell, Decio L. Eizirik, Mark Peakman
Journal: Diabetes
Diabetes 2011;60(8):2112–2119
https://doi.org/10.2337/db10-1643
Published: 18 July 2011
View articletitled, Peripheral and Islet Interleukin-17 Pathway Activation Characterizes Human Autoimmune Diabetes and Promotes Cytokine-Mediated β-Cell Death
Open the PDF for Peripheral and Islet Interleukin-17 Pathway Activation Characterizes Human Autoimmune Diabetes and Promotes Cytokine-Mediated β-Cell Death in another window
Includes: Supplementary data
Journal Articles

Plasmacytoid Dendritic Cells Are Proportionally Expanded at Diagnosis of Type 1 Diabetes and Enhance Islet Autoantigen Presentation to T-Cells Through Immune Complex Capture

Jennifer S. Allen, Karl Pang, Ania Skowera, Richard Ellis, Chloe Rackham, Biliana Lozanoska-Ochser, Timothy Tree, R. David G. Leslie, Jennifer M. Tremble, Colin M. Dayan, Mark Peakman
Journal: Diabetes
Diabetes 2009;58(1):138–145
https://doi.org/10.2337/db08-0964
Published: 01 January 2009
View articletitled, Plasmacytoid Dendritic Cells Are Proportionally Expanded at Diagnosis of Type 1 Diabetes and Enhance Islet Autoantigen Presentation to T-Cells Through Immune Complex Capture
Open the PDF for Plasmacytoid Dendritic Cells Are Proportionally Expanded at Diagnosis of Type 1 Diabetes and Enhance Islet Autoantigen Presentation to T-Cells Through Immune Complex Capture in another window
Includes: Supplementary data
Journal Articles

Defective Suppressor Function in CD4+CD25+ T-Cells From Patients With Type 1 Diabetes

Shelley Lindley, Colin M. Dayan, Amanda Bishop, Bart O. Roep, Mark Peakman, Timothy I.M. Tree
Journal: Diabetes
Diabetes 2005;54(1):92–99
https://doi.org/10.2337/diabetes.54.1.92
Published: 01 January 2005
View articletitled, Defective Suppressor Function in CD4+CD25+ T-Cells From Patients With Type 1 Diabetes
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Journal Articles

Characterization of the T-Cell Response to Coxsackievirus B4: Evidence That Effector Memory Cells Predominate in Patients With Type 1 Diabetes

Ruben Varela-Calvino, Richard Ellis, Gianluca Sgarbi, Colin M. Dayan, Mark Peakman
Journal: Diabetes
Diabetes 2002;51(6):1745–1753
https://doi.org/10.2337/diabetes.51.6.1745
Published: 01 June 2002
View articletitled, Characterization of the T-Cell Response to Coxsackievirus B4: Evidence That Effector Memory Cells Predominate in Patients With Type 1 Diabetes
Open the PDF for Characterization of the T-Cell Response to Coxsackievirus B4: Evidence That Effector Memory Cells Predominate in Patients With Type 1 Diabetes in another window