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Journal Articles

Pathways Targeted by Antidiabetes Drugs Are Enriched for Multiple Genes Associated With Type 2 Diabetes Risk

Free
Ayellet V. Segrè, Nancy Wei, DIAGRAM Consortium, MAGIC Investigators, David Altshuler, Jose C. Florez
Journal: Diabetes
Diabetes 2015;64(4):1470–1483
https://doi.org/10.2337/db14-0703
Published: 03 November 2014
View articletitled, Pathways Targeted by Antidiabetes Drugs Are Enriched for Multiple Genes Associated With Type 2 Diabetes Risk
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Includes: Supplementary data
Journal Articles

Expression of Phosphofructokinase in Skeletal Muscle Is Influenced by Genetic Variation and Associated With Insulin Sensitivity

Open Access
Sarah Keildson, Joao Fadista, Claes Ladenvall, Åsa K. Hedman, Targ Elgzyri, Kerrin S. Small, Elin Grundberg, Alexandra C. Nica, Daniel Glass, J. Brent Richards, Amy Barrett, James Nisbet, Hou-Feng Zheng, Tina Rönn, Kristoffer Ström, Karl-Fredrik Eriksson, Inga Prokopenko, MAGIC Consortium, DIAGRAM Consortium, MuTHER Consortium, Timothy D. Spector, Emmanouil T. Dermitzakis, Panos Deloukas, Mark I. McCarthy, Johan Rung, Leif Groop, Paul W. Franks, Cecilia M. Lindgren, Ola Hansson
Journal: Diabetes
Diabetes 2014;63(3):1154–1165
https://doi.org/10.2337/db13-1301
Published: 13 February 2014
View articletitled, Expression of Phosphofructokinase in Skeletal Muscle Is Influenced by Genetic Variation and Associated With Insulin Sensitivity
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Includes: Supplementary data
Journal Articles

Genetic Variants Associated With Glycine Metabolism and Their Role in Insulin Sensitivity and Type 2 Diabetes

Open Access
Weijia Xie, Andrew R. Wood, Valeriya Lyssenko, Michael N. Weedon, Joshua W. Knowles, Sami Alkayyali, Themistocles L. Assimes, Thomas Quertermous, Fahim Abbasi, Jussi Paananen, Hans Häring, Torben Hansen, Oluf Pedersen, Ulf Smith, Markku Laakso, the MAGIC Investigators, the DIAGRAM Consortium, the GENESIS Consortium, the RISC Consortium, Jacqueline M. Dekker, John J. Nolan, Leif Groop, Ele Ferrannini, Klaus-Peter Adam, Walter E. Gall, Timothy M. Frayling, Mark Walker
Journal: Diabetes
Diabetes 2013;62(6):2141–2150
https://doi.org/10.2337/db12-0876
Published: 17 May 2013
View articletitled, Genetic Variants Associated With Glycine Metabolism and Their Role in Insulin Sensitivity and Type 2 Diabetes
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Includes: Supplementary data
Journal Articles

A Genome-Wide Association Study Identifies GRK5 and RASGRP1 as Type 2 Diabetes Loci in Chinese Hans

Open Access
Huaixing Li, Wei Gan, Ling Lu, Xiao Dong, Xueyao Han, Cheng Hu, Zhen Yang, Liang Sun, Wei Bao, Pengtao Li, Meian He, Liangdan Sun, Yiqin Wang, Jingwen Zhu, Qianqian Ning, Yong Tang, Rong Zhang, Jie Wen, Di Wang, Xilin Zhu, Kunquan Guo, Xianbo Zuo, Xiaohui Guo, Handong Yang, Xianghai Zhou, DIAGRAM Consortium, AGEN-T2D Consortium, Xuejun Zhang, Lu Qi, Ruth J.F. Loos, Frank B. Hu, Tangchun Wu, Ying Liu, Liegang Liu, Ze Yang, Renming Hu, Weiping Jia, Linong Ji, Yixue Li, Xu Lin
Journal: Diabetes
Diabetes 2013;62(1):291–298
https://doi.org/10.2337/db12-0454
Published: 13 December 2012
View articletitled, A Genome-Wide Association Study Identifies GRK5 and RASGRP1 as Type 2 Diabetes Loci in Chinese Hans
Open the PDF for A Genome-Wide Association Study Identifies GRK5 and RASGRP1 as Type 2 Diabetes Loci in Chinese Hans in another window
Includes: Supplementary data
Journal Articles

Impact of Common Variation in Bone-Related Genes on Type 2 Diabetes and Related Traits

Open Access
Liana K. Billings, Yi-Hsiang Hsu, Rachel J. Ackerman, Josée Dupuis, Benjamin F. Voight, Laura J. Rasmussen-Torvik, Serge Hercberg, Mark Lathrop, Daniel Barnes, Claudia Langenberg, Jennie Hui, Mao Fu, Nabila Bouatia-Naji, Cecile Lecoeur, Ping An, Patrik K. Magnusson, Ida Surakka, Samuli Ripatti, Lene Christiansen, Christine Dalgård, Lasse Folkersen, Elin Grundberg, the MAGIC Investigators, the DIAGRAM + Consortium, the MuTHER Consortium, the ASCOT Investigators, the GEFOS Consortium, Per Eriksson, Jaakko Kaprio, Kirsten Ohm Kyvik, Nancy L. Pedersen, Ingrid B. Borecki, Michael A. Province, Beverley Balkau, Philippe Froguel, Alan R. Shuldiner, Lyle J. Palmer, Nick Wareham, Pierre Meneton, Toby Johnson, James S. Pankow, David Karasik, James B. Meigs, Douglas P. Kiel, Jose C. Florez
Journal: Diabetes
Diabetes 2012;61(8):2176–2186
https://doi.org/10.2337/db11-1515
Published: 17 July 2012
View articletitled, Impact of Common Variation in Bone-Related Genes on Type 2 Diabetes and Related Traits
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Includes: Supplementary data
Journal Articles

Low-Frequency Variants in HMGA1 Are Not Associated With Type 2 Diabetes Risk

Open Access
Marcel Marquez, Marlène Huyvaert, John R.B. Perry, Richard D. Pearson, Mario Falchi, Andrew P. Morris, Sidonie Vivequin, Stéphane Lobbens, Loïc Yengo, Stefan Gaget, Francois Pattou, Odile Poulain-Godefroy, Guillaume Charpentier, Lena M.S. Carlsson, Peter Jacobson, Lars Sjöström, Olivier Lantieri, Barbara Heude, Andrew Walley, Beverley Balkau, Michel Marre, the DIAGRAM Consortium, Philippe Froguel, Stéphane Cauchi
Journal: Diabetes
Diabetes 2012;61(2):524–530
https://doi.org/10.2337/db11-0728
Published: 17 January 2012
View articletitled, Low-Frequency Variants in HMGA1 Are Not Associated With Type 2 Diabetes Risk
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Includes: Supplementary data
Journal Articles

Genome-Wide Association Identifies Nine Common Variants Associated With Fasting Proinsulin Levels and Provides New Insights Into the Pathophysiology of Type 2 Diabetes

Open Access
Rona J. Strawbridge, Josée Dupuis, Inga Prokopenko, Adam Barker, Emma Ahlqvist, Denis Rybin, John R. Petrie, Mary E. Travers, Nabila Bouatia-Naji, Antigone S. Dimas, Alexandra Nica, Eleanor Wheeler, Han Chen, Benjamin F. Voight, Jalal Taneera, Stavroula Kanoni, John F. Peden, Fabiola Turrini, Stefan Gustafsson, Carina Zabena, Peter Almgren, David J.P. Barker, Daniel Barnes, Elaine M. Dennison, Johan G. Eriksson, Per Eriksson, Elodie Eury, Lasse Folkersen, Caroline S. Fox, Timothy M. Frayling, Anuj Goel, Harvest F. Gu, Momoko Horikoshi, Bo Isomaa, Anne U. Jackson, Karen A. Jameson, Eero Kajantie, Julie Kerr-Conte, Teemu Kuulasmaa, Johanna Kuusisto, Ruth J.F. Loos, Jian'an Luan, Konstantinos Makrilakis, Alisa K. Manning, María Teresa Martínez-Larrad, Narisu Narisu, Maria Nastase Mannila, John Öhrvik, Clive Osmond, Laura Pascoe, Felicity Payne, Avan A. Sayer, Bengt Sennblad, Angela Silveira, Alena Stančáková, Kathy Stirrups, Amy J. Swift, Ann-Christine Syvänen, Tiinamaija Tuomi, Ferdinand M. van 't Hooft, Mark Walker, Michael N. Weedon, Weijia Xie, Björn Zethelius, the DIAGRAM Consortium, the GIANT Consortium, the MuTHER Consortium, the CARDIoGRAM Consortium, the C4D Consortium, Halit Ongen, Anders Mälarstig, Jemma C. Hopewell, Danish Saleheen, John Chambers, Sarah Parish, John Danesh, Jaspal Kooner, Claes-Göran Östenson, Lars Lind, Cyrus C. Cooper, Manuel Serrano-Ríos, Ele Ferrannini, Tom J. Forsen, Robert Clarke, Maria Grazia Franzosi, Udo Seedorf, Hugh Watkins, Philippe Froguel, Paul Johnson, Panos Deloukas, Francis S. Collins, Markku Laakso, Emmanouil T. Dermitzakis, Michael Boehnke, Mark I. McCarthy, Nicholas J. Wareham, Leif Groop, François Pattou, Anna L. Gloyn, George V. Dedoussis, Valeriya Lyssenko, James B. Meigs, Inês Barroso, Richard M. Watanabe, Erik Ingelsson, Claudia Langenberg, Anders Hamsten, Jose C. Florez
Journal: Diabetes
Diabetes 2011;60(10):2624–2634
https://doi.org/10.2337/db11-0415
Published: 16 September 2011
View articletitled, Genome-Wide Association Identifies Nine Common Variants Associated With Fasting Proinsulin Levels and Provides New Insights Into the Pathophysiology of Type 2 Diabetes
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Includes: Supplementary data
Journal Articles

Updated Genetic Score Based on 34 Confirmed Type 2 Diabetes Loci Is Associated With Diabetes Incidence and Regression to Normoglycemia in the Diabetes Prevention Program

Open Access
Marie-France Hivert, Kathleen A. Jablonski, Leigh Perreault, Richa Saxena, Jarred B. McAteer, Paul W. Franks, Richard F. Hamman, Steven E. Kahn, Steven Haffner, the DIAGRAM Consortium, James B. Meigs, David Altshuler, William C. Knowler, Jose C. Florez, for the Diabetes Prevention Program Research Group
Journal: Diabetes
Diabetes 2011;60(4):1340–1348
https://doi.org/10.2337/db10-1119
Published: 22 March 2011
View articletitled, Updated Genetic Score Based on 34 Confirmed Type 2 Diabetes Loci Is Associated With Diabetes Incidence and Regression to Normoglycemia in the Diabetes Prevention Program
Open the PDF for Updated Genetic Score Based on 34 Confirmed Type 2 Diabetes Loci Is Associated With Diabetes Incidence and Regression to Normoglycemia in the Diabetes Prevention Program in another window
Includes: Supplementary data