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David B. Savage
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Journal Articles

Perilipin 1 Antibodies in Patients With Acquired Generalized Lipodystrophy

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David B. Savage
Journal: Diabetes
Diabetes 2023;72(1):16–18
https://doi.org/10.2337/dbi22-0022
Published: 14 December 2022
View articletitled, Perilipin 1 Antibodies in Patients With Acquired Generalized Lipodystrophy
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Journal Articles

A Pharmacogenetic Approach to the Treatment of Patients With PPARG Mutations

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Maura Agostini, Erik Schoenmakers, Junaid Beig, Louise Fairall, Istvan Szatmari, Odelia Rajanayagam, Frederick W. Muskett, Claire Adams, A. David Marais, Stephen O’Rahilly, Robert K. Semple, Laszlo Nagy, Amit R. Majithia, John W.R. Schwabe, Dirk J. Blom, Rinki Murphy, Krishna Chatterjee, David B. Savage
Journal: Diabetes
Diabetes 2018;67(6):1086–1092
https://doi.org/10.2337/db17-1236
Published: 05 April 2018
View articletitled, A Pharmacogenetic Approach to the Treatment of Patients With PPARG Mutations
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Includes: Supplementary data
Journal Articles

Common Genetic Variants Highlight the Role of Insulin Resistance and Body Fat Distribution in Type 2 Diabetes, Independent of Obesity

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Robert A. Scott, Tove Fall, Dorota Pasko, Adam Barker, Stephen J. Sharp, Larraitz Arriola, Beverley Balkau, Aurelio Barricarte, Inês Barroso, Heiner Boeing, Françoise Clavel-Chapelon, Francesca L. Crowe, Jacqueline M. Dekker, Guy Fagherazzi, Ele Ferrannini, Nita G. Forouhi, Paul W. Franks, Diana Gavrila, Vilmantas Giedraitis, Sara Grioni, Leif C. Groop, Rudolf Kaaks, Timothy J. Key, Tilman Kühn, Luca A. Lotta, Peter M. Nilsson, Kim Overvad, Domenico Palli, Salvatore Panico, J. Ramón Quirós, Olov Rolandsson, Nina Roswall, Carlotta Sacerdote, Núria Sala, María-José Sánchez, Matthias B. Schulze, Afshan Siddiq, Nadia Slimani, Ivonne Sluijs, Annemieke M.W. Spijkerman, Anne Tjonneland, Rosario Tumino, Daphne L. van der A, Hanieh Yaghootkar, The RISC Study Group, The EPIC-InterAct Consortium, Mark I. McCarthy, Robert K. Semple, Elio Riboli, Mark Walker, Erik Ingelsson, Tim M. Frayling, David B. Savage, Claudia Langenberg, Nicholas J. Wareham
Journal: Diabetes
Diabetes 2014;63(12):4378–4387
https://doi.org/10.2337/db14-0319
Published: 13 November 2014
View articletitled, Common Genetic Variants Highlight the Role of Insulin Resistance and Body Fat Distribution in Type 2 Diabetes, Independent of Obesity
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Includes: Supplementary data
Journal Articles

Clinical and Molecular Characterization of a Novel PLIN1 Frameshift Mutation Identified in Patients With Familial Partial Lipodystrophy

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Kristina Kozusko, Venessa H.M. Tsang, William Bottomley, Yoon-Hi Cho, Sheetal Gandotra, Michael Mimmack, Koini Lim, Iona Isaac, Satish Patel, Vladimir Saudek, Stephen O’Rahilly, Shubha Srinivasan, Jerry R. Greenfield, Ines Barroso, Lesley V. Campbell, David B. Savage
Journal: Diabetes
Diabetes 2015;64(1):299–310
https://doi.org/10.2337/db14-0104
Published: 11 August 2014
View articletitled, Clinical and Molecular Characterization of a Novel PLIN1 Frameshift Mutation Identified in Patients With Familial Partial Lipodystrophy
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Includes: Supplementary data
Journal Articles

TCF7L2 Polymorphisms Modulate Proinsulin Levels and β-Cell Function in a British Europid Population

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Ruth J.F. Loos, Paul W. Franks, Richard W. Francis, Inês Barroso, Fiona M. Gribble, David B. Savage, Ken K. Ong, Stephen O'Rahilly, Nicholas J. Wareham
Journal: Diabetes
Diabetes 2007;56(7):1943–1947
https://doi.org/10.2337/db07-0055
Published: 01 July 2007
View articletitled, TCF7L2 Polymorphisms Modulate Proinsulin Levels and β-Cell Function in a British Europid Population
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Includes: Supplementary data
Journal Articles

Rosiglitazone Increases Indexes of Stearoyl-CoA Desaturase Activity in Humans: Link to Insulin Sensitization and the Role of Dominant-Negative Mutation in Peroxisome Proliferator-Activated Receptor-γ

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Ulf Risérus, Garry D. Tan, Barbara A. Fielding, Matt J. Neville, Jenny Currie, David B. Savage, V. Krishna Chatterjee, Keith N. Frayn, Stephen O’Rahilly, Fredrik Karpe
Journal: Diabetes
Diabetes 2005;54(5):1379–1384
https://doi.org/10.2337/diabetes.54.5.1379
Published: 01 May 2005
View articletitled, Rosiglitazone Increases Indexes of Stearoyl-CoA Desaturase Activity in Humans: Link to Insulin Sensitization and the Role of Dominant-Negative Mutation in Peroxisome Proliferator-Activated Receptor-γ
Open the PDF for Rosiglitazone Increases Indexes of Stearoyl-CoA Desaturase Activity in Humans: Link to Insulin Sensitization and the Role of Dominant-Negative Mutation in Peroxisome Proliferator-Activated Receptor-γ in another window
Journal Articles

Human Metabolic Syndrome Resulting From Dominant-Negative Mutations in the Nuclear Receptor Peroxisome Proliferator-Activated Receptor-γ

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David B. Savage, Garry D. Tan, Carlo L. Acerini, Susan A. Jebb, Maura Agostini, Mark Gurnell, Rachel L. Williams, A. Margot Umpleby, E. Louise Thomas, Jimmy D. Bell, Adrian K. Dixon, Fidelma Dunne, Romina Boiani, Saverio Cinti, Antonio Vidal-Puig, Fredrik Karpe, V. Krishna K. Chatterjee, Stephen O’Rahilly
Journal: Diabetes
Diabetes 2003;52(4):910–917
https://doi.org/10.2337/diabetes.52.4.910
Published: 01 April 2003
View articletitled, Human Metabolic Syndrome Resulting From Dominant-Negative Mutations in the Nuclear Receptor Peroxisome Proliferator-Activated Receptor-γ
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Journal Articles

Resistin / Fizz3 Expression in Relation to Obesity and Peroxisome Proliferator–Activated Receptor-γ Action in Humans

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David B. Savage, Ciaran P. Sewter, Ellen S. Klenk, David G. Segal, Antonio Vidal-Puig, Robert V. Considine, Stephen O’Rahilly
Journal: Diabetes
Diabetes 2001;50(10):2199–2202
https://doi.org/10.2337/diabetes.50.10.2199
Published: 01 October 2001
View articletitled, Resistin / Fizz3 Expression in Relation to Obesity and Peroxisome Proliferator–Activated Receptor-γ Action in Humans
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