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Journal Articles

Classics in Diabetes

David D’Alessio, the Editorial Team
Journal: Diabetes
Diabetes 2023;72(9):1179
https://doi.org/10.2337/dbi23-0016
Published: 21 August 2023
View article titled, Classics in <em>Diabetes</em>
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Meeting Abstracts

325-OR: ß-Arrestin 1 Regulates Glucagon-Like Peptide-1 Receptor Mediated Insulin Secretion in a Ligand-Dependent Manner

JONATHAN D. DOUROS, II, KYLE SLOOP, JONATHAN CAMPBELL, DAVID D’ALESSIO
Journal: Diabetes
Diabetes 2020;69(Supplement_1):325-OR
https://doi.org/10.2337/db20-325-OR
Published: 01 June 2020
View article titled, 325-OR: ß-Arrestin 1 Regulates Glucagon-Like Peptide-1 Receptor Mediated Insulin Secretion in a Ligand-Dependent Manner
Meeting Abstracts

324-OR: The Incretin Action of GIP Is Mediated through Both Alpha and Beta Cells

KIMBERLEY M. EL, MEGAN CAPOZZI, SARAH M. GRAY, JENNIFER L. BROWN, FRANCIS S. WILLARD, PAUL EMMERSON, KYLE SLOOP, DAVID D’ALESSIO, JONATHAN CAMPBELL
Journal: Diabetes
Diabetes 2020;69(Supplement_1):324-OR
https://doi.org/10.2337/db20-324-OR
Published: 01 June 2020
View article titled, 324-OR: The Incretin Action of GIP Is Mediated through Both Alpha and Beta Cells
Meeting Abstracts

255-LB: Impaired Gsa/cAMP Signaling Exclusive to Pancreatic ß-Cells Exhibits a Unique Urinary Metabolome via Nontargeted Metabolomics in a Murine Model of Diabetes In Vivo

AMRO ILAIWY, MEGAN CAPOZZI, JENNIFER L. BROWN, DAVID D’ALESSIO, JONATHAN CAMPBELL
Journal: Diabetes
Diabetes 2020;69(Supplement_1):255-LB
https://doi.org/10.2337/db20-255-LB
Published: 01 June 2020
View article titled, 255-LB: Impaired Gsa/cAMP Signaling Exclusive to Pancreatic ß-Cells Exhibits a Unique Urinary Metabolome via Nontargeted Metabolomics in a Murine Model of Diabetes In Vivo
Meeting Abstracts

2113-P: Discrepancy between Single-Cell RNA Sequencing and Protein Expression Assessments of GLP-1Rr Heterogeneity in Beta Cells

SARAH M. GRAY, BRYANNA M. CHAZOTTE, ELIZABETH C. ROSS, BERIT SVENDSEN, PETER RAVN, KYLE SLOOP, JONATHAN CAMPBELL, DAVID D’ALESSIO
Journal: Diabetes
Diabetes 2020;69(Supplement_1):2113-P
https://doi.org/10.2337/db20-2113-P
Published: 01 June 2020
View article titled, 2113-P: Discrepancy between Single-Cell RNA Sequencing and Protein Expression Assessments of GLP-1Rr Heterogeneity in Beta Cells
Meeting Abstracts

2095-P: ß-Cell Glucose-Dependent Insulinotropic Polypeptide Receptors Are Necessary for Improved Islet Function following Sleeve Gastrectomy

JONATHAN D. DOUROS, II, JONATHAN CAMPBELL, JENNY TONG, DAVID D’ALESSIO
Journal: Diabetes
Diabetes 2020;69(Supplement_1):2095-P
https://doi.org/10.2337/db20-2095-P
Published: 01 June 2020
View article titled, 2095-P: ß-Cell Glucose-Dependent Insulinotropic Polypeptide Receptors Are Necessary for Improved Islet Function following Sleeve Gastrectomy
Meeting Abstracts

2125-P: Incretin-Stimulated Insulin Secretion Is Mediated by Gas Dependent and Independent Mechanisms

MEGAN CAPOZZI, SARAH M. GRAY, PAUL EMMERSON, FRANCIS S. WILLARD, KYLE SLOOP, DAVID D’ALESSIO, JONATHAN CAMPBELL
Journal: Diabetes
Diabetes 2020;69(Supplement_1):2125-P
https://doi.org/10.2337/db20-2125-P
Published: 01 June 2020
View article titled, 2125-P: Incretin-Stimulated Insulin Secretion Is Mediated by Gas Dependent and Independent Mechanisms
Meeting Abstracts

The TCF7L2 Variant rs7903146 Affects the Risk of Youth-Onset Type 2 Diabetes by Reducing the Incretin Effect on Insulin Secretion

ALFONSO GALDERISI, BRIDGET PIERPONT, DAVID D'ALESSIO, NICOLA SANTORO, SONIA CAPRIO
Journal: Diabetes
Diabetes 2018;67(Supplement_1):340-OR
https://doi.org/10.2337/db18-340-OR
Published: 01 July 2018
View article titled, The TCF7L2 Variant rs7903146 Affects the Risk of Youth-Onset Type 2 Diabetes by Reducing the Incretin Effect on Insulin Secretion
Meeting Abstracts

High Iron Feeding Modulates Glucose Metabolism in Duodenal-Jejunal Bypass Surgery but Not in Vertical Sleeve Gastrectomy in Mice

JINGJING NIU, JONATHAN D. DOUROS, II, JONATHAN CAMPBELL, MEGAN CAPOZZI, SARAH M. GRAY, FELIPE LORENZO, DAVID D'ALESSIO, DON MCCLAIN, JENNY TONG
Journal: Diabetes
Diabetes 2018;67(Supplement_1):2023-P
https://doi.org/10.2337/db18-2023-P
Published: 01 July 2018
View article titled, High Iron Feeding Modulates Glucose Metabolism in Duodenal-Jejunal Bypass Surgery but Not in Vertical Sleeve Gastrectomy in Mice
Meeting Abstracts

Glucagon Receptor Antagonist LGD-6972 Significantly Lowers HbA1c and Is Well Tolerated after 12-Week Treatment in Patients with Type 2 Diabetes Mellitus (T2DM) on Metformin

JEREMY PETTUS, ERIC G. VAJDA, JAMES PIPKIN, GRETCHEN WILLIAMSON, MIRIAM A. ZANGMEISTER, YONG-XI LI, ROBERT R. HENRY, DAVID D'ALESSIO, JUAN P. FRIAS, LIN ZHI, KEITH MARSCHKE
Journal: Diabetes
Diabetes 2018;67(Supplement_1):73-OR
https://doi.org/10.2337/db18-73-OR
Published: 01 July 2018
View article titled, Glucagon Receptor Antagonist LGD-6972 Significantly Lowers HbA1c and Is Well Tolerated after 12-Week Treatment in Patients with Type 2 Diabetes Mellitus (T2DM) on Metformin
Journal Articles

An Innate Disposition for a Healthier Gut: GLP-1R Signaling in Intestinal Epithelial Lymphocytes

Wilfredo Rosario, David D’Alessio
Journal: Diabetes
Diabetes 2015;64(7):2329–2331
https://doi.org/10.2337/db15-0436
Published: 17 June 2015
View article titled, An Innate Disposition for a Healthier Gut: GLP-1R Signaling in Intestinal Epithelial Lymphocytes
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Journal Articles

Exenatide Protects Against Glucose- and Lipid-Induced Endothelial Dysfunction: Evidence for Direct Vasodilation Effect of GLP-1 Receptor Agonists in Humans

Juraj Koska, Michelle Sands, Camelia Burciu, Karen M. D’Souza, Kalyani Raravikar, James Liu, Seth Truran, Daniel A. Franco, Eric A. Schwartz, Dawn C. Schwenke, David D’Alessio, Raymond Q. Migrino, Peter D. Reaven
Journal: Diabetes
Diabetes 2015;64(7):2624–2635
https://doi.org/10.2337/db14-0976
Published: 26 February 2015
View article titled, Exenatide Protects Against Glucose- and Lipid-Induced Endothelial Dysfunction: Evidence for Direct Vasodilation Effect of GLP-1 Receptor Agonists in Humans
Open the PDF for Exenatide Protects Against Glucose- and Lipid-Induced Endothelial Dysfunction: Evidence for Direct Vasodilation Effect of GLP-1 Receptor Agonists in Humans in another window
Includes: Supplementary data
Journal Articles

Acute Administration of Unacylated Ghrelin Has No Effect on Basal or Stimulated Insulin Secretion in Healthy Humans

Jenny Tong, Harold W. Davis, Suzanne Summer, Stephen C. Benoit, Ahrar Haque, Martin Bidlingmaier, Matthias H. Tschöp, David D’Alessio
Journal: Diabetes
Diabetes 2014;63(7):2309–2319
https://doi.org/10.2337/db13-1598
Published: 14 June 2014
View article titled, Acute Administration of Unacylated Ghrelin Has No Effect on Basal or Stimulated Insulin Secretion in Healthy Humans
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Journal Articles

Give the Receptor a Brake: Slowing Gastric Emptying by GLP-1

Jenny Tong, David D’Alessio
Journal: Diabetes
Diabetes 2014;63(2):407–409
https://doi.org/10.2337/db13-1764
Published: 16 January 2014
View article titled, Give the Receptor a Brake: Slowing Gastric Emptying by GLP-1
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Journal Articles

Fibroblast Growth Factor 21 Mediates Specific Glucagon Actions

Kirk M. Habegger, Kerstin Stemmer, Christine Cheng, Timo D. Müller, Kristy M. Heppner, Nickki Ottaway, Jenna Holland, Jazzminn L. Hembree, David Smiley, Vasily Gelfanov, Radha Krishna, Ayman M. Arafat, Anish Konkar, Sara Belli, Martin Kapps, Stephen C. Woods, Susanna M. Hofmann, David D’Alessio, Paul T. Pfluger, Diego Perez-Tilve, Randy J. Seeley, Morichika Konishi, Nobuyujki Itoh, Alexei Kharitonenkov, Joachim Spranger, Richard D. DiMarchi, Matthias H. Tschöp
Journal: Diabetes
Diabetes 2013;62(5):1453–1463
https://doi.org/10.2337/db12-1116
Published: 16 April 2013
View article titled, Fibroblast Growth Factor 21 Mediates Specific Glucagon Actions
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Includes: Supplementary data
Journal Articles

Impaired Insulin Secretion and Enhanced Insulin Sensitivity in Cholecystokinin-Deficient Mice

Chun-Min Lo, Silvana Obici, H. Henry Dong, Michael Haas, Dawnwen Lou, Dae Hyun Kim, Min Liu, David D’Alessio, Stephen C. Woods, Patrick Tso
Journal: Diabetes
Diabetes 2011;60(7):2000–2007
https://doi.org/10.2337/db10-0789
Published: 20 June 2011
View article titled, Impaired Insulin Secretion and Enhanced Insulin Sensitivity in Cholecystokinin-Deficient Mice
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Includes: Supplementary data
Journal Articles

Ghrelin Suppresses Glucose-Stimulated Insulin Secretion and Deteriorates Glucose Tolerance in Healthy Humans

Jenny Tong, Ronald L. Prigeon, Harold W. Davis, Martin Bidlingmaier, Steven E. Kahn, David E. Cummings, Matthias H. Tschöp, David D'Alessio
Journal: Diabetes
Diabetes 2010;59(9):2145–2151
https://doi.org/10.2337/db10-0504
Published: 28 June 2010
View article titled, Ghrelin Suppresses Glucose-Stimulated Insulin Secretion and Deteriorates Glucose Tolerance in Healthy Humans
Open the PDF for Ghrelin Suppresses Glucose-Stimulated Insulin Secretion and Deteriorates Glucose Tolerance in Healthy Humans in another window
Includes: Supplementary data