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David M. Harlan
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Meeting Abstracts

549-P: Assessing Feasibility of a Diabetes Mellitus Program Using Behavioral Economics to Optimize Outreach and Self-Management Support with Technology—The DM-BOOST Project

DANIEL J. AMANTE, LISA L. SHENETTE, GERALDINE PUERTO, STEPHENIE LEMON, DAVID M. HARLAN, BEN S. GERBER
Journal: Diabetes
Diabetes 2023;72(Supplement_1):549-P
https://doi.org/10.2337/db23-549-P
Published: 20 June 2023
View article titled, 549-P: Assessing Feasibility of a Diabetes Mellitus Program Using Behavioral Economics to Optimize Outreach and Self-Management Support with Technology—The DM-BOOST Project
Journal Articles

An Early Islet Transcriptional Signature Is Associated With Local Inflammation in Autoimmune Diabetes

Alan G. Derr, Adediwura Arowosegbe, Basanthi Satish, Sambra D. Redick, Natasha Qaisar, Zhiru Guo, Emma Vanderleeden, Melanie I. Trombly, Christina E. Baer, David M. Harlan, Dale L. Greiner, Manuel Garber, Jennifer P. Wang
Journal: Diabetes
Diabetes 2023;72(2):261–274
https://doi.org/10.2337/db22-0521
Published: 08 November 2022
View article titled, An Early Islet Transcriptional Signature Is Associated With Local Inflammation in Autoimmune Diabetes
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Journal Articles

HLA Class II Antigen Processing and Presentation Pathway Components Demonstrated by Transcriptome and Protein Analyses of Islet β-Cells From Donors With Type 1 Diabetes

Mark A. Russell, Sambra D. Redick, David M. Blodgett, Sarah J. Richardson, Pia Leete, Lars Krogvold, Knut Dahl-Jørgensen, Rita Bottino, Marcela Brissova, Jason M. Spaeth, Jenny Aurielle B. Babon, Rachana Haliyur, Alvin C. Powers, Chaoxing Yang, Sally C. Kent, Alan G. Derr, Alper Kucukural, Manuel G. Garber, Noel G. Morgan, David M. Harlan
Journal: Diabetes
Diabetes 2019;68(5):988–1001
https://doi.org/10.2337/db18-0686
Published: 04 March 2019
View article titled, HLA Class II Antigen Processing and Presentation Pathway Components Demonstrated by Transcriptome and Protein Analyses of Islet β-Cells From Donors With Type 1 Diabetes
Open the PDF for HLA Class II Antigen Processing and Presentation Pathway Components Demonstrated by Transcriptome and Protein Analyses of Islet β-Cells From Donors With Type 1 Diabetes in another window
Includes: Multimedia, Supplementary data
Journal Articles

Modifying Enzymes Are Elicited by ER Stress, Generating Epitopes That Are Selectively Recognized by CD4+ T Cells in Patients With Type 1 Diabetes

Meghan L. Marre, John W. McGinty, I-Ting Chow, Megan E. DeNicola, Noah W. Beck, Sally C. Kent, Alvin C. Powers, Rita Bottino, David M. Harlan, Carla J. Greenbaum, William W. Kwok, Jon D. Piganelli, Eddie A. James
Journal: Diabetes
Diabetes 2018;67(7):1356–1368
https://doi.org/10.2337/db17-1166
Published: 13 April 2018
View article titled, Modifying Enzymes Are Elicited by ER Stress, Generating Epitopes That Are Selectively Recognized by CD4<sup>+</sup> T Cells in Patients With Type 1 Diabetes
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Includes: Supplementary data
Journal Articles

Novel Observations From Next-Generation RNA Sequencing of Highly Purified Human Adult and Fetal Islet Cell Subsets

David M. Blodgett, Anetta Nowosielska, Shaked Afik, Susanne Pechhold, Anthony J. Cura, Norman J. Kennedy, Soyoung Kim, Alper Kucukural, Roger J. Davis, Sally C. Kent, Dale L. Greiner, Manuel G. Garber, David M. Harlan, Philip diIorio
Journal: Diabetes
Diabetes 2015;64(9):3172–3181
https://doi.org/10.2337/db15-0039
Published: 30 April 2015
View article titled, Novel Observations From Next-Generation RNA Sequencing of Highly Purified Human Adult and Fetal Islet Cell Subsets
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Includes: Supplementary data
Journal Articles

Evaluating the Role of Epigenetic Histone Modifications in the Metabolic Memory of Type 1 Diabetes

Feng Miao, Zhuo Chen, Saul Genuth, Andrew Paterson, Lingxiao Zhang, Xiwei Wu, Sierra Min Li, Patricia Cleary, Arthur Riggs, David M. Harlan, Gayle Lorenzi, Orville Kolterman, Wanjie Sun, John M. Lachin, Rama Natarajan, the DCCT/EDIC Research Group
Journal: Diabetes
Diabetes 2014;63(5):1748–1762
https://doi.org/10.2337/db13-1251
Published: 12 April 2014
View article titled, Evaluating the Role of Epigenetic Histone Modifications in the Metabolic Memory of Type 1 Diabetes
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Includes: Supplementary data
Journal Articles

Comment on: Keenan et al. (2010) Residual Insulin Production and Pancreatic β-Cell Turnover After 50 Years of Diabetes: Joslin Medalist Study. Diabetes 2010;59:2846–2853

Kristina I. Rother, David M. Harlan
Journal: Diabetes
Diabetes 2010;59(12):e26
https://doi.org/10.2337/db10-1207
Published: 01 December 2010
View article titled, Comment on: Keenan et al. (2010) Residual Insulin Production and Pancreatic β-Cell Turnover After 50 Years of Diabetes: Joslin Medalist Study. Diabetes 2010;59:2846–2853
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Journal Articles

Current Advances and Travails in Islet Transplantation

David M. Harlan, Norma Sue Kenyon, Olle Korsgren, Bart O. Roep, for the Immunology of Diabetes Society
Journal: Diabetes
Diabetes 2009;58(10):2175–2184
https://doi.org/10.2337/db09-0476
Published: 01 October 2009
View article titled, Current Advances and Travails in Islet Transplantation
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Journal Articles

Dynamic Changes in Pancreatic Endocrine Cell Abundance, Distribution, and Function in Antigen-Induced and Spontaneous Autoimmune Diabetes

Klaus Pechhold, Xiaolong Zhu, Victor S. Harrison, Janet Lee, Sagarika Chakrabarty, Kerstin Koczwara, Oksana Gavrilova, David M. Harlan
Journal: Diabetes
Diabetes 2009;58(5):1175–1184
https://doi.org/10.2337/db08-0616
Published: 19 February 2009
View article titled, Dynamic Changes in Pancreatic Endocrine Cell Abundance, Distribution, and Function in Antigen-Induced and Spontaneous Autoimmune Diabetes
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Includes: Supplementary data
Journal Articles

A Single Course of Anti-CD3 Monoclonal Antibody hOKT3γ1(Ala-Ala) Results in Improvement in C-Peptide Responses and Clinical Parameters for at Least 2 Years after Onset of Type 1 Diabetes

Kevan C. Herold, Stephen E. Gitelman, Umesh Masharani, William Hagopian, Brygida Bisikirska, David Donaldson, Kristina Rother, Beverly Diamond, David M. Harlan, Jeffrey A. Bluestone
Journal: Diabetes
Diabetes 2005;54(6):1763–1769
https://doi.org/10.2337/diabetes.54.6.1763
Published: 01 June 2005
View article titled, A Single Course of Anti-CD3 Monoclonal Antibody hOKT3γ1(Ala-Ala) Results in Improvement in C-Peptide Responses and Clinical Parameters for at Least 2 Years after Onset of Type 1 Diabetes
Open the PDF for A Single Course of Anti-CD3 Monoclonal Antibody hOKT3γ1(Ala-Ala) Results in Improvement in C-Peptide Responses and Clinical Parameters for at Least 2 Years after Onset of Type 1 Diabetes in another window
Journal Articles

Insulin Secretion in Type 1 Diabetes

Chynna Steele, William A. Hagopian, Stephen Gitelman, Umesh Masharani, Melissa Cavaghan, Kristina I. Rother, David Donaldson, David M. Harlan, Jeffrey Bluestone, Kevan C. Herold
Journal: Diabetes
Diabetes 2004;53(2):426–433
https://doi.org/10.2337/diabetes.53.2.426
Published: 01 February 2004
View article titled, Insulin Secretion in Type 1 Diabetes
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Journal Articles

Pancreatic Islet Transplantation Using the Nonhuman Primate (Rhesus) Model Predicts That the Portal Vein Is Superior to the Celiac Artery as the Islet Infusion Site

Boaz Hirshberg, Sean Montgomery, Michael G. Wysoki, He Xu, Doug Tadaki, Janet Lee, Kenneth Hines, Jason Gaglia, Noelle Patterson, John Leconte, Douglas Hale, Richard Chang, Alan D. Kirk, David M. Harlan
Journal: Diabetes
Diabetes 2002;51(7):2135–2140
https://doi.org/10.2337/diabetes.51.7.2135
Published: 01 July 2002
View article titled, Pancreatic Islet Transplantation Using the Nonhuman Primate (Rhesus) Model Predicts That the Portal Vein Is Superior to the Celiac Artery as the Islet Infusion Site
Open the PDF for Pancreatic Islet Transplantation Using the Nonhuman Primate (Rhesus) Model Predicts That the Portal Vein Is Superior to the Celiac Artery as the Islet Infusion Site in another window
Journal Articles

Very-Low-Dose Streptozotocin Induces Diabetes in Insulin Promoter-mB7-1 Transgenic Mice

David M Harlan, Michelle A Barnett, Ryo Abe, Klaus Pechhold, Noelle B Patterson, Gary S Gray, Carl H June
Journal: Diabetes
Diabetes 1995;44(7):816–823
https://doi.org/10.2337/diab.44.7.816
Published: 01 July 1995
View article titled, Very-Low-Dose Streptozotocin Induces Diabetes in Insulin Promoter-mB7-1 Transgenic Mice
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