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David W. Piston
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Meeting Abstracts

1838-P: A Genetically Encoded Reporter for Targeted Glucagon Secretion Studies in Alpha Cells

Free
ALESSANDRO USTIONE, DAHLIA A. ABDULSATTAR, DAVID W. PISTON
Journal: Diabetes
Diabetes 2025;74(Supplement_1):1838-P
https://doi.org/10.2337/db25-1838-P
Published: 20 June 2025
View article titled, 1838-P: A Genetically Encoded Reporter for Targeted Glucagon Secretion Studies in Alpha Cells
Journal Articles

Regulation of Type 1 Diabetes via Brown Adipocyte–Secreted Proteins and the Novel Glucagon Regulator Nidogen-2

Available to Purchase
Jeongmin Lee, Alessandro Ustione, Emily M. Wilkerson, Rekha Balakrishnan, Debbie C. Thurmond, Dennis Goldfarb, David W. Piston
Journal: Diabetes
Diabetes 2025;74(6):907–920
https://doi.org/10.2337/db24-1003
Published: 28 February 2025
View article titled, Regulation of Type 1 Diabetes via Brown Adipocyte–Secreted Proteins and the Novel Glucagon Regulator Nidogen-2
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Journal Articles

Loss of β-Cell KATP Reduces Ca2+ Sensitivity of Insulin Secretion and Trpm5 Expression

Available to Purchase
Nathaniel W. York, Zihan Yan, Anna B. Osipovich, Abbie Tate, Sumit Patel, David W. Piston, Mark A. Magnuson, Maria S. Remedi, Colin G. Nichols
Journal: Diabetes
Diabetes 2025;74(3):376–383
https://doi.org/10.2337/db24-0650
Published: 12 December 2024
View article titled, Loss of β-Cell KATP Reduces Ca2+ Sensitivity of Insulin Secretion and Trpm5 Expression
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Meeting Abstracts

1653-P: Brown Adipocyte–Secreted Factors for Treating Type 1 Diabetes Mellitus

Free
JEONGMIN LEE, DAVID W. PISTON
Journal: Diabetes
Diabetes 2023;72(Supplement_1):1653-P
https://doi.org/10.2337/db23-1653-P
Published: 20 June 2023
View article titled, 1653-P: Brown Adipocyte–Secreted Factors for Treating Type 1 Diabetes Mellitus
Meeting Abstracts

26-OR: A Novel Drug That Normalizes Hyperglycemia in Type 1 Diabetes

Free
FARZAD ASADI, SUBHADRA C. GUNAWARDANA, DAVID W. PISTON
Journal: Diabetes
Diabetes 2023;72(Supplement_1):26-OR
https://doi.org/10.2337/db23-26-OR
Published: 20 June 2023
View article titled, 26-OR: A Novel Drug That Normalizes Hyperglycemia in Type 1 Diabetes
Journal Articles

Sorting Out the Receptor Isoforms Underlying Dopamine Inhibition of Insulin Secretion

Free
Melkam A. Kebede, David W. Piston
Journal: Diabetes
Diabetes 2022;71(9):1831–1833
https://doi.org/10.2337/dbi22-0018
Published: 11 August 2022
View article titled, Sorting Out the Receptor Isoforms Underlying Dopamine Inhibition of Insulin Secretion
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Journal Articles

RhoA as a Signaling Hub Controlling Glucagon Secretion From Pancreatic α-Cells

Free
Xue Wen Ng, Yong Hee Chung, Farzad Asadi, Chen Kong, Alessandro Ustione, David W. Piston
Journal: Diabetes
Diabetes 2022;71(11):2384–2394
https://doi.org/10.2337/db21-1010
Published: 29 July 2022
View article titled, RhoA as a Signaling Hub Controlling Glucagon Secretion From Pancreatic α-Cells
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Meeting Abstracts

193-OR: Glycemic Control via Glucagon Modulation by a Novel Brown Adipose Peptide Hormone

Free
DAVID W. PISTON, ALESSANDRO USTIONE, SUBHADRA C. GUNAWARDANA, JING HUGHES
Journal: Diabetes
Diabetes 2019;68(Supplement_1):193-OR
https://doi.org/10.2337/db19-193-OR
Published: 01 June 2019
View article titled, 193-OR: Glycemic Control via Glucagon Modulation by a Novel Brown Adipose Peptide Hormone
Meeting Abstracts

Functional Characterization of Wolfram Syndrome 1 Protein in ß-Cell Function and Viability

Free
DAMIEN ABREU, ZENO LAVAGNINO, CRIS M. BROWN, DAVID W. PISTON, FUMIHIKO URANO
Journal: Diabetes
Diabetes 2018;67(Supplement_1):2114-P
https://doi.org/10.2337/db18-2114-P
Published: 01 July 2018
View article titled, Functional Characterization of Wolfram Syndrome 1 Protein in ß-Cell Function and Viability
Journal Articles

Reestablishment of Glucose Inhibition of Glucagon Secretion in Small Pseudoislets

Free
Christopher A. Reissaus, David W. Piston
Journal: Diabetes
Diabetes 2017;66(4):960–969
https://doi.org/10.2337/db16-1291
Published: 27 January 2017
View article titled, Reestablishment of Glucose Inhibition of Glucagon Secretion in Small Pseudoislets
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Includes: Supplementary data
Journal Articles

EphA4 Receptor Forward Signaling Inhibits Glucagon Secretion From α-Cells

Free
Troy Hutchens, David W. Piston
Journal: Diabetes
Diabetes 2015;64(11):3839–3851
https://doi.org/10.2337/db15-0488
Published: 06 August 2015
View article titled, EphA4 Receptor Forward Signaling Inhibits Glucagon Secretion From α-Cells
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Includes: Supplementary data
Journal Articles

The MafA Transcription Factor Becomes Essential to Islet β-Cells Soon After Birth

Open Access
Yan Hang, Tsunehiko Yamamoto, Richard K.P. Benninger, Marcela Brissova, Min Guo, Will Bush, David W. Piston, Alvin C. Powers, Mark Magnuson, Debbie C. Thurmond, Roland Stein
Journal: Diabetes
Diabetes 2014;63(6):1994–2005
https://doi.org/10.2337/db13-1001
Published: 15 May 2014
View article titled, The MafA Transcription Factor Becomes Essential to Islet β-Cells Soon After Birth
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Includes: Supplementary data
Journal Articles

Connexin-36 Gap Junctions Regulate In Vivo First- and Second-Phase Insulin Secretion Dynamics and Glucose Tolerance in the Conscious Mouse

Open Access
W. Steven Head, Meredith L. Orseth, Craig S. Nunemaker, Leslie S. Satin, David W. Piston, Richard K.P. Benninger
Journal: Diabetes
Diabetes 2012;61(7):1700–1707
https://doi.org/10.2337/db11-1312
Published: 14 June 2012
View article titled, Connexin-36 Gap Junctions Regulate In Vivo First- and Second-Phase Insulin Secretion Dynamics and Glucose Tolerance in the Conscious Mouse
Open the PDF for Connexin-36 Gap Junctions Regulate In Vivo First- and Second-Phase Insulin Secretion Dynamics and Glucose Tolerance in the Conscious Mouse in another window
Includes: Supplementary data
Journal Articles

Reversal of Type 1 Diabetes in Mice by Brown Adipose Tissue Transplant

Open Access
Subhadra C. Gunawardana, David W. Piston
Journal: Diabetes
Diabetes 2012;61(3):674–682
https://doi.org/10.2337/db11-0510
Published: 13 February 2012
View article titled, Reversal of Type 1 Diabetes in Mice by Brown Adipose Tissue Transplant
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Includes: Supplementary data
Journal Articles

Direct Effect of Cholesterol on Insulin Secretion: A Novel Mechanism for Pancreatic β-Cell Dysfunction

Free
Mingming Hao, W. Steven Head, Subhadra C. Gunawardana, Alyssa H. Hasty, David W. Piston
Journal: Diabetes
Diabetes 2007;56(9):2328–2338
https://doi.org/10.2337/db07-0056
Published: 01 September 2007
View article titled, Direct Effect of Cholesterol on Insulin Secretion: A Novel Mechanism for Pancreatic β-Cell Dysfunction
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Journal Articles

Mechanisms of Time-Dependent Potentiation of Insulin Release: Involvement of Nitric Oxide Synthase

Free
Subhadra C. Gunawardana, Jonathan V. Rocheleau, W. Steven Head, David W. Piston
Journal: Diabetes
Diabetes 2006;55(4):1029–1033
https://doi.org/10.2337/diabetes.55.04.06.db05-1532
Published: 01 April 2006
View article titled, Mechanisms of Time-Dependent Potentiation of Insulin Release: Involvement of Nitric Oxide Synthase
Open the PDF for Mechanisms of Time-Dependent Potentiation of Insulin Release: Involvement of Nitric Oxide Synthase in another window