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Journal Articles

Natural Variation in Interleukin-2 Sensitivity Influences Regulatory T-Cell Frequency and Function in Individuals With Long-standing Type 1 Diabetes

Jennie H.M. Yang, Antony J. Cutler, Ricardo C. Ferreira, James L. Reading, Nicholas J. Cooper, Chris Wallace, Pamela Clarke, Deborah J. Smyth, Christopher S. Boyce, Guo-Jian Gao, John A. Todd, Linda S. Wicker, Timothy I.M. Tree

Diabetes 2015;64(11):3891–3902

https://doi.org/10.2337/db15-0516

Published: 29 July 2015

View article titled, Natural Variation in Interleukin-2 Sensitivity Influences Regulatory T-Cell Frequency and Function in Individuals With Long-standing Type 1 Diabetes

Includes: Supplementary data

Journal Articles

A Type I Interferon Transcriptional Signature Precedes Autoimmunity in Children Genetically at Risk for Type 1 Diabetes

Diabetes 2014;63(7):2538–2550

https://doi.org/10.2337/db13-1777

Published: 14 June 2014

View article titled, A Type I Interferon Transcriptional Signature Precedes Autoimmunity in Children Genetically at Risk for Type 1 Diabetes

Includes: Supplementary data

Journal Articles

Evidence of Gene-Gene Interaction and Age-at-Diagnosis Effects in Type 1 Diabetes

Joanna M.M. Howson, Jason D. Cooper, Deborah J. Smyth, Neil M. Walker, Helen Stevens, Jin-Xiong She, George S. Eisenbarth, Marian Rewers, John A. Todd, Beena Akolkar, Patrick Concannon, Henry A. Erlich, Cécile Julier, Grant Morahan, Jørn Nerup, Concepcion Nierras, Flemming Pociot, Stephen S. Rich, and the Type 1 Diabetes Genetics Consortium

Diabetes 2012;61(11):3012–3017

https://doi.org/10.2337/db11-1694

Published: 16 October 2012

View article titled, Evidence of Gene-Gene Interaction and Age-at-Diagnosis Effects in Type 1 Diabetes

Includes: Supplementary data

Journal Articles

FUT2 Nonsecretor Status Links Type 1 Diabetes Susceptibility and Resistance to Infection

Deborah J. Smyth, Jason D. Cooper, Joanna M.M. Howson, Pamela Clarke, Kate Downes, Trupti Mistry, Helen Stevens, Neil M. Walker, John A. Todd

Diabetes 2011;60(11):3081–3084

https://doi.org/10.2337/db11-0638

Published: 17 October 2011

View article titled, FUT2 Nonsecretor Status Links Type 1 Diabetes Susceptibility and Resistance to Infection

Includes: Supplementary data

Journal Articles

Genetic Analysis of Adult-Onset Autoimmune Diabetes

Joanna M.M. Howson, Silke Rosinger, Deborah J. Smyth, Bernhard O. Boehm, the ADBW-END Study Group, John A. Todd

Diabetes 2011;60(10):2645–2653

https://doi.org/10.2337/db11-0364

Published: 16 September 2011

View article titled, Genetic Analysis of Adult-Onset Autoimmune Diabetes

Includes: Supplementary data

Journal Articles

Evidence That HLA Class I and II Associations With Type 1 Diabetes, Autoantibodies to GAD and Autoantibodies to IA-2, Are Distinct

Joanna M.M. Howson, Helen Stevens, Deborah J. Smyth, Neil M. Walker, Kyla A. Chandler, Polly J. Bingley, John A. Todd

Diabetes 2011;60(10):2635–2644

https://doi.org/10.2337/db11-0131

Published: 16 September 2011

View article titled, Evidence That HLA Class I and II Associations With Type 1 Diabetes, Autoantibodies to GAD and Autoantibodies to IA-2, Are Distinct

Includes: Supplementary data

Journal Articles

Inherited Variation in Vitamin D Genes Is Associated With Predisposition to Autoimmune Disease Type 1 Diabetes

Jason D. Cooper, Deborah J. Smyth, Neil M. Walker, Helen Stevens, Oliver S. Burren, Chris Wallace, Christopher Greissl, Elizabeth Ramos-Lopez, Elina Hyppönen, David B. Dunger, Timothy D. Spector, Willem H. Ouwehand, Thomas J. Wang, Klaus Badenhoop, John A. Todd

Diabetes 2011;60(5):1624–1631

https://doi.org/10.2337/db10-1656

Published: 23 April 2011

View article titled, Inherited Variation in Vitamin D Genes Is Associated With Predisposition to Autoimmune Disease Type 1 Diabetes

Journal Articles

An Allele of IKZF1 (Ikaros) Conferring Susceptibility to Childhood Acute Lymphoblastic Leukemia Protects Against Type 1 Diabetes

Austin D.-E. Swafford, Joanna M.M. Howson, Lucy J. Davison, Chris Wallace, Deborah J. Smyth, Helen Schuilenburg, Meeta Maisuria-Armer, Trupti Mistry, Michael J. Lenardo, John A. Todd

Diabetes 2011;60(3):1041–1044

https://doi.org/10.2337/db10-0446

Published: 21 February 2011

View article titled, An Allele of IKZF1 (Ikaros) Conferring Susceptibility to Childhood Acute Lymphoblastic Leukemia Protects Against Type 1 Diabetes

Includes: Supplementary data

Journal Articles

A Human Type 1 Diabetes Susceptibility Locus Maps to Chromosome 21q22.3

Patrick Concannon, Suna Onengut-Gumuscu, John A. Todd, Deborah J. Smyth, Flemming Pociot, Regine Bergholdt, Beena Akolkar, Henry A. Erlich, Joan E. Hilner, Cécile Julier, Grant Morahan, Jørn Nerup, Concepcion R. Nierras, Wei-Min Chen, Stephen S. Rich, the Type 1 Diabetes Genetics Consortium

Diabetes 2008;57(10):2858–2861

https://doi.org/10.2337/db08-0753

Published: 01 October 2008

View article titled, A Human Type 1 Diabetes Susceptibility Locus Maps to Chromosome 21q22.3

Journal Articles

PTPN22 Trp⁶²⁰ Explains the Association of Chromosome 1p13 With Type 1 Diabetes and Shows a Statistical Interaction With HLA Class II Genotypes

Deborah J. Smyth, Jason D. Cooper, Joanna M.M. Howson, Neil M. Walker, Vincent Plagnol, Helen Stevens, David G. Clayton, John A. Todd

Diabetes 2008;57(6):1730–1737

https://doi.org/10.2337/db07-1131

Published: 01 June 2008

View article titled, PTPN22 Trp620 Explains the Association of Chromosome 1p13 With Type 1 Diabetes and Shows a Statistical Interaction With HLA Class II Genotypes

Includes: Supplementary data

Journal Articles

Association of the Vitamin D Metabolism Gene CYP27B1 With Type 1 Diabetes

Rebecca Bailey, Jason D. Cooper, Lauren Zeitels, Deborah J. Smyth, Jennie H.M. Yang, Neil M. Walker, Elina Hyppönen, David B. Dunger, Elizabeth Ramos-Lopez, Klaus Badenhoop, Sergey Nejentsev, John A. Todd

Diabetes 2007;56(10):2616–2621

https://doi.org/10.2337/db07-0652

Published: 01 October 2007

View article titled, Association of the Vitamin D Metabolism Gene CYP27B1 With Type 1 Diabetes

Includes: Supplementary data

Journal Articles

No Evidence for Association of OAS1 With Type 1 Diabetes in Unaffected Siblings or Type 1 Diabetic Cases

Deborah J. Smyth, Jason D. Cooper, Christopher E. Lowe, Sarah Nutland, Neil M. Walker, David G. Clayton, John A. Todd

Diabetes 2006;55(5):1525–1528

https://doi.org/10.2337/db05-1452

Published: 01 May 2006

View article titled, No Evidence for Association of OAS1 With Type 1 Diabetes in Unaffected Siblings or Type 1 Diabetic Cases

Includes: Supplementary data

Journal Articles

Analysis of the Type 2 Diabetes-Associated Single Nucleotide Polymorphisms in the Genes IRS1, KCNJ11, and PPARG2 in Type 1 Diabetes

Christina Eftychi, Joanna M.M. Howson, Bryan J. Barratt, Adrian Vella, Felicity Payne, Deborah J. Smyth, Rebecca C.J. Twells, Neil M. Walker, Helen E. Rance, Eva Tuomilehto-Wolf, Jaakko Tuomilehto, Dag E. Undlien, Kjersti S. Rønningen, Cristian Guja, Constantin Ionescu-Tı̂irgovişte, David A. Savage, John A. Todd

Diabetes 2004;53(3):870–873

https://doi.org/10.2337/diabetes.53.3.870

Published: 01 March 2004

View article titled, Analysis of the Type 2 Diabetes-Associated Single Nucleotide Polymorphisms in the Genes IRS1, KCNJ11, and PPARG2 in Type 1 Diabetes

Journal Articles

Haplotype Tag Single Nucleotide Polymorphism Analysis of the Human Orthologues of the Rat Type 1 Diabetes Genes Ian4 (Lyp/Iddm1) and Cblb

Felicity Payne, Deborah J. Smyth, Rebecca Pask, Bryan J. Barratt, Jason D. Cooper, Rebecca C.J. Twells, Neil M. Walker, Alex C. Lam, Luc J. Smink, Sarah Nutland, Helen E. Rance, John A. Todd

Diabetes 2004;53(2):505–509

https://doi.org/10.2337/diabetes.53.2.505

Published: 01 February 2004

View article titled, Haplotype Tag Single Nucleotide Polymorphism Analysis of the Human Orthologues of the Rat Type 1 Diabetes Genes Ian4 (Lyp/Iddm1) and Cblb

NARROW

Natural Variation in Interleukin-2 Sensitivity Influences Regulatory T-Cell Frequency and Function in Individuals With Long-standing Type 1 Diabetes

A Type I Interferon Transcriptional Signature Precedes Autoimmunity in Children Genetically at Risk for Type 1 Diabetes

Evidence of Gene-Gene Interaction and Age-at-Diagnosis Effects in Type 1 Diabetes

FUT2 Nonsecretor Status Links Type 1 Diabetes Susceptibility and Resistance to Infection

Genetic Analysis of Adult-Onset Autoimmune Diabetes

Evidence That HLA Class I and II Associations With Type 1 Diabetes, Autoantibodies to GAD and Autoantibodies to IA-2, Are Distinct

Inherited Variation in Vitamin D Genes Is Associated With Predisposition to Autoimmune Disease Type 1 Diabetes

An Allele of IKZF1 (Ikaros) Conferring Susceptibility to Childhood Acute Lymphoblastic Leukemia Protects Against Type 1 Diabetes

A Human Type 1 Diabetes Susceptibility Locus Maps to Chromosome 21q22.3

PTPN22 Trp⁶²⁰ Explains the Association of Chromosome 1p13 With Type 1 Diabetes and Shows a Statistical Interaction With HLA Class II Genotypes

Association of the Vitamin D Metabolism Gene CYP27B1 With Type 1 Diabetes

No Evidence for Association of OAS1 With Type 1 Diabetes in Unaffected Siblings or Type 1 Diabetic Cases

Analysis of the Type 2 Diabetes-Associated Single Nucleotide Polymorphisms in the Genes IRS1, KCNJ11, and PPARG2 in Type 1 Diabetes

Haplotype Tag Single Nucleotide Polymorphism Analysis of the Human Orthologues of the Rat Type 1 Diabetes Genes Ian4 (Lyp/Iddm1) and Cblb

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