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Deborah M. Muoio
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Journal Articles

SIRT3 Directs Carbon Traffic in Muscle to Promote Glucose Control

Frank K. Huynh, Deborah M. Muoio, Matthew D. Hirschey
Journal: Diabetes
Diabetes 2015;64(9):3058–3060
https://doi.org/10.2337/db15-0709
Published: 13 August 2015
View article titled, SIRT3 Directs Carbon Traffic in Muscle to Promote Glucose Control
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Journal Articles

Muscle-Specific Overexpression of PGC-1α Does Not Augment Metabolic Improvements in Response to Exercise and Caloric Restriction

Kari E. Wong, Catherine R. Mikus, Dorothy H. Slentz, Sarah E. Seiler, Karen L. DeBalsi, Olga R. Ilkayeva, Karen I. Crain, Michael T. Kinter, C. Lawrence Kien, Robert D. Stevens, Deborah M. Muoio
Journal: Diabetes
Diabetes 2015;64(5):1532–1543
https://doi.org/10.2337/db14-0827
Published: 24 November 2014
View article titled, Muscle-Specific Overexpression of PGC-1α Does Not Augment Metabolic Improvements in Response to Exercise and Caloric Restriction
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Includes: Supplementary data
Journal Articles

Downregulation of Carnitine Acyl-Carnitine Translocase by miRNAs 132 and 212 Amplifies Glucose-Stimulated Insulin Secretion

Mufaddal S. Soni, Mary E. Rabaglia, Sushant Bhatnagar, Jin Shang, Olga Ilkayeva, Randall Mynatt, Yun-Ping Zhou, Eric E. Schadt, Nancy A. Thornberry, Deborah M. Muoio, Mark P. Keller, Alan D. Attie
Journal: Diabetes
Diabetes 2014;63(11):3805–3814
https://doi.org/10.2337/db13-1677
Published: 13 October 2014
View article titled, Downregulation of Carnitine Acyl-Carnitine Translocase by miRNAs 132 and 212 Amplifies Glucose-Stimulated Insulin Secretion
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Includes: Supplementary data
Journal Articles

Compartmentalized Acyl-CoA Metabolism in Skeletal Muscle Regulates Systemic Glucose Homeostasis

Lei O. Li, Trisha J. Grevengoed, David S. Paul, Olga Ilkayeva, Timothy R. Koves, Florencia Pascual, Christopher B. Newgard, Deborah M. Muoio, Rosalind A. Coleman
Journal: Diabetes
Diabetes 2015;64(1):23–35
https://doi.org/10.2337/db13-1070
Published: 28 July 2014
View article titled, Compartmentalized Acyl-CoA Metabolism in Skeletal Muscle Regulates Systemic Glucose Homeostasis
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Includes: Supplementary data
Journal Articles

A Lipidomics Analysis of the Relationship Between Dietary Fatty Acid Composition and Insulin Sensitivity in Young Adults

C. Lawrence Kien, Janice Y. Bunn, Matthew E. Poynter, Robert Stevens, James Bain, Olga Ikayeva, Naomi K. Fukagawa, Catherine M. Champagne, Karen I. Crain, Timothy R. Koves, Deborah M. Muoio
Journal: Diabetes
Diabetes 2013;62(4):1054–1063
https://doi.org/10.2337/db12-0363
Published: 14 March 2013
View article titled, A Lipidomics Analysis of the Relationship Between Dietary Fatty Acid Composition and Insulin Sensitivity in Young Adults
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Includes: Supplementary data
Journal Articles

Metabolic Remodeling of Human Skeletal Myocytes by Cocultured Adipocytes Depends on the Lipolytic State of the System

Jean-Paul Kovalik, Dorothy Slentz, Robert D. Stevens, William E. Kraus, Joseph A. Houmard, James B. Nicoll, Y. Renee Lea-Currie, Karen Everingham, C. Lawrence Kien, Benjamin M. Buehrer, Deborah M. Muoio
Journal: Diabetes
Diabetes 2011;60(7):1882–1893
https://doi.org/10.2337/db10-0427
Published: 20 June 2011
View article titled, Metabolic Remodeling of Human Skeletal Myocytes by Cocultured Adipocytes Depends on the Lipolytic State of the System
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Includes: Supplementary data
Journal Articles

Inhibition of De Novo Ceramide Synthesis Reverses Diet-Induced Insulin Resistance and Enhances Whole-Body Oxygen Consumption

John R. Ussher, Timothy R. Koves, Virgilio J.J. Cadete, Liyan Zhang, Jagdip S. Jaswal, Suzanne J. Swyrd, David G. Lopaschuk, Spencer D. Proctor, Wendy Keung, Deborah M. Muoio, Gary D. Lopaschuk
Journal: Diabetes
Diabetes 2010;59(10):2453–2464
https://doi.org/10.2337/db09-1293
Published: 03 June 2010
View article titled, Inhibition of De Novo Ceramide Synthesis Reverses Diet-Induced Insulin Resistance and Enhances Whole-Body Oxygen Consumption
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Includes: Supplementary data
Journal Articles

Alterations in Skeletal Muscle Fatty Acid Handling Predisposes Middle-Aged Mice to Diet-Induced Insulin Resistance

Debby P.Y. Koonen, Miranda M.Y. Sung, Cindy K.C. Kao, Vernon W. Dolinsky, Timothy R. Koves, Olga Ilkayeva, René L. Jacobs, Dennis E. Vance, Peter E. Light, Deborah M. Muoio, Maria Febbraio, Jason R.B. Dyck
Journal: Diabetes
Diabetes 2010;59(6):1366–1375
https://doi.org/10.2337/db09-1142
Published: 31 March 2010
View article titled, Alterations in Skeletal Muscle Fatty Acid Handling Predisposes Middle-Aged Mice to Diet-Induced Insulin Resistance
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Includes: Supplementary data
Journal Articles

Peroxisome Proliferator–Activated Receptor-γ Coactivator-1α Overexpression Increases Lipid Oxidation in Myocytes From Extremely Obese Individuals

Leslie A. Consitt, Jill A. Bell, Timothy R. Koves, Deborah M. Muoio, Matthew W. Hulver, Kimberly R. Haynie, G. Lynis Dohm, Joseph A. Houmard
Journal: Diabetes
Diabetes 2010;59(6):1407–1415
https://doi.org/10.2337/db09-1704
Published: 03 March 2010
View article titled, Peroxisome Proliferator–Activated Receptor-γ Coactivator-1α Overexpression Increases Lipid Oxidation in Myocytes From Extremely Obese Individuals
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Journal Articles

Metabolomics Applied to Diabetes Research: Moving From Information to Knowledge

James R. Bain, Robert D. Stevens, Brett R. Wenner, Olga Ilkayeva, Deborah M. Muoio, Christopher B. Newgard
Journal: Diabetes
Diabetes 2009;58(11):2429–2443
https://doi.org/10.2337/db09-0580
Published: 01 November 2009
View article titled, Metabolomics Applied to Diabetes Research: <subtitle>Moving From Information to Knowledge</subtitle>
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Journal Articles

Insulin-Stimulated Cardiac Glucose Oxidation Is Increased in High-Fat Diet–Induced Obese Mice Lacking Malonyl CoA Decarboxylase

John R. Ussher, Timothy R. Koves, Jagdip S. Jaswal, Liyan Zhang, Olga Ilkayeva, Jason R.B. Dyck, Deborah M. Muoio, Gary D. Lopaschuk
Journal: Diabetes
Diabetes 2009;58(8):1766–1775
https://doi.org/10.2337/db09-0011
Published: 28 May 2009
View article titled, Insulin-Stimulated Cardiac Glucose Oxidation Is Increased in High-Fat Diet–Induced Obese Mice Lacking Malonyl CoA Decarboxylase
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Includes: Supplementary data
Journal Articles

Fatty Acid Oxidation and Insulin Action: When Less Is More

Deborah M. Muoio, Christopher B. Newgard
Journal: Diabetes
Diabetes 2008;57(6):1455–1456
https://doi.org/10.2337/db08-0281
Published: 01 June 2008
View article titled, Fatty Acid Oxidation and Insulin Action: <subtitle>When Less Is More</subtitle>
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Journal Articles

Peroxisome Proliferator-Activated Receptor-α Regulates Fatty Acid Utilization in Primary Human Skeletal Muscle Cells

Deborah M. Muoio, James M. Way, Charles J. Tanner, Deborah A. Winegar, Steven A. Kliewer, Joseph A. Houmard, William E. Kraus, G. Lynis Dohm
Journal: Diabetes
Diabetes 2002;51(4):901–909
https://doi.org/10.2337/diabetes.51.4.901
Published: 01 April 2002
View article titled, Peroxisome Proliferator-Activated Receptor-α Regulates Fatty Acid Utilization in Primary Human Skeletal Muscle Cells
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Journal Articles

Leptin Directly Alters Lipid Partitioning in Skeletal Muscle

Deborah M Muoio, G Lynis Dohn, Frederick T Fiedorek, Jr, Edward B Tapscott, Rosalind A Coleman
Journal: Diabetes
Diabetes 1997;46(8):1360–1363
https://doi.org/10.2337/diab.46.8.1360
Published: 01 August 1997
View article titled, Leptin Directly Alters Lipid Partitioning in Skeletal Muscle
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