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Diego Perez-Tilve
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Journal Articles

CB1 and GLP-1 Receptors Cross Talk Provides New Therapies for Obesity

Philippe Zizzari, Rongjun He, Sarah Falk, Luigi Bellocchio, Camille Allard, Samantha Clark, Thierry Lesté-Lasserre, Giovanni Marsicano, Christoffer Clemmensen, Diego Perez-Tilve, Brian Finan, Daniela Cota, Carmelo Quarta
Journal: Diabetes
Diabetes 2021;70(2):415–422
https://doi.org/10.2337/db20-0162
Published: 03 November 2020
View article titled, CB1 and GLP-1 Receptors Cross Talk Provides New Therapies for Obesity
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Meeting Abstracts

296-LB: Novel Analogs of the Mitochondrially Encoded Peptide CB5064 Improve Body Weight and Glucose Tolerance in Dio Mice, and Demonstrate Selective Agonism at the Apelin Receptor

KENT GRINDSTAFF, EMILY STENGER, ROBIN SHANG, TRACY YU, WENDY C. LUO, VIRNA V. KIM, DIEGO PEREZ-TILVE, KENNETH C. CUNDY
Journal: Diabetes
Diabetes 2019;68(Supplement_1):296-LB
https://doi.org/10.2337/db19-296-LB
Published: 01 June 2019
View article titled, 296-LB: Novel Analogs of the Mitochondrially Encoded Peptide CB5064 Improve Body Weight and Glucose Tolerance in Dio Mice, and Demonstrate Selective Agonism at the Apelin Receptor
Journal Articles

Hepatic Glucagon Receptor Signaling Enhances Insulin-Stimulated Glucose Disposal in Rodents

Teayoun Kim, Cassie L. Holleman, Shelly Nason, Deanna M. Arble, Nickki Ottaway, Joseph Chabenne, Christine Loyd, Jeong-a Kim, Darleen Sandoval, Daniel J. Drucker, Richard DiMarchi, Diego Perez-Tilve, Kirk M. Habegger
Journal: Diabetes
Diabetes 2018;67(11):2157–2166
https://doi.org/10.2337/db18-0068
Published: 27 August 2018
View article titled, Hepatic Glucagon Receptor Signaling Enhances Insulin-Stimulated Glucose Disposal in Rodents
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Includes: Supplementary data
Meeting Abstracts

CB4211 Is a Potential Treatment for Metabolic Diseases with a Novel Mechanism of Action—Sensitization of the Insulin Receptor

KENT GRINDSTAFF, REMI MAGNAN, ROBIN SHANG, EMILY STENGER, JENNA S. HOLLAND, DIEGO PEREZ-TILVE, KENNETH C. CUNDY
Journal: Diabetes
Diabetes 2018;67(Supplement_1):233-LB
https://doi.org/10.2337/db18-233-LB
Published: 01 July 2018
View article titled, CB4211 Is a Potential Treatment for Metabolic Diseases with a Novel Mechanism of Action—Sensitization of the Insulin Receptor
Meeting Abstracts

Glucagon-Receptor Signaling Regulates Mitochondrial Bioenergetics via Hepatic Farnesol X Receptor

TEAYOUN KIM, SHELLY NASON, JESSICA P. ANTIPENKO, CATHERINA S. VESTRI, KELLEY SMITH-JOHNSTON, MARK E. PEPIN, ADAM R. WENDE, BRIAN FINAN, RICHARD DIMARCHI, DIEGO PEREZ-TILVE, DOUGLAS R. MOELLERING, KIRK M. HABEGGER
Journal: Diabetes
Diabetes 2018;67(Supplement_1):1978-P
https://doi.org/10.2337/db18-1978-P
Published: 01 July 2018
View article titled, Glucagon-Receptor Signaling Regulates Mitochondrial Bioenergetics via Hepatic Farnesol X Receptor
Journal Articles

Glucagon Receptor Signaling Regulates Energy Metabolism via Hepatic Farnesoid X Receptor and Fibroblast Growth Factor 21

Teayoun Kim, Shelly Nason, Cassie Holleman, Mark Pepin, Landon Wilson, Taylor F. Berryhill, Adam R. Wende, Chad Steele, Martin E. Young, Stephen Barnes, Daniel J. Drucker, Brian Finan, Richard DiMarchi, Diego Perez-Tilve, Matthias Tschöp, Kirk M. Habegger
Journal: Diabetes
Diabetes 2018;67(9):1773–1782
https://doi.org/10.2337/db17-1502
Published: 20 June 2018
View article titled, Glucagon Receptor Signaling Regulates Energy Metabolism via Hepatic Farnesoid X Receptor and Fibroblast Growth Factor 21
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Includes: Supplementary data
Journal Articles

GLP-1R Responsiveness Predicts Individual Gastric Bypass Efficacy on Glucose Tolerance in Rats

Kirk M. Habegger, Kristy M. Heppner, Sarah E. Amburgy, Nickki Ottaway, Jenna Holland, Christine Raver, Erin Bartley, Timo D. Müller, Paul T. Pfluger, Jose Berger, Mouhamadoul Toure, Stephen C. Benoit, Richard D. DiMarchi, Diego Perez-Tilve, David A. D’Alessio, Randy J. Seeley, Matthias H. Tschöp
Journal: Diabetes
Diabetes 2014;63(2):505–513
https://doi.org/10.2337/db13-0511
Published: 16 January 2014
View article titled, GLP-1R Responsiveness Predicts Individual Gastric Bypass Efficacy on Glucose Tolerance in Rats
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Includes: Supplementary data
Journal Articles

Both Acyl and Des-Acyl Ghrelin Regulate Adiposity and Glucose Metabolism via Central Nervous System Ghrelin Receptors

Kristy M. Heppner, Carolin L. Piechowski, Anne Müller, Nickki Ottaway, Stephanie Sisley, David L. Smiley, Kirk M. Habegger, Paul T. Pfluger, Richard DiMarchi, Heike Biebermann, Matthias H. Tschöp, Darleen A. Sandoval, Diego Perez-Tilve
Journal: Diabetes
Diabetes 2014;63(1):122–131
https://doi.org/10.2337/db13-0414
Published: 13 December 2013
View article titled, Both Acyl and Des-Acyl Ghrelin Regulate Adiposity and Glucose Metabolism via Central Nervous System Ghrelin Receptors
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Journal Articles

GLP-1R Agonism Enhances Adjustable Gastric Banding in Diet-Induced Obese Rats

Kirk M. Habegger, Henriette Kirchner, Chun-Xia Yi, Kristy M. Heppner, Dan Sweeney, Nickki Ottaway, Jenna Holland, Sarah Amburgy, Christine Raver, Radhakrishna Krishna, Timo D. Müller, Diego Perez-Tilve, Paul T. Pfluger, Silvana Obici, Richard D. DiMarchi, David A. D’Alessio, Randy J. Seeley, Matthias H. Tschöp
Journal: Diabetes
Diabetes 2013;62(9):3261–3267
https://doi.org/10.2337/db13-0117
Published: 15 August 2013
View article titled, GLP-1R Agonism Enhances Adjustable Gastric Banding in Diet-Induced Obese Rats
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Journal Articles

Vertical Sleeve Gastrectomy Is Effective in Two Genetic Mouse Models of Glucagon-Like Peptide 1 Receptor Deficiency

Hilary E. Wilson-Pérez, Adam P. Chambers, Karen K. Ryan, Bailing Li, Darleen A. Sandoval, Doris Stoffers, Daniel J. Drucker, Diego Pérez-Tilve, Randy J. Seeley
Journal: Diabetes
Diabetes 2013;62(7):2380–2385
https://doi.org/10.2337/db12-1498
Published: 14 June 2013
View article titled, Vertical Sleeve Gastrectomy Is Effective in Two Genetic Mouse Models of Glucagon-Like Peptide 1 Receptor Deficiency
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Includes: Supplementary data
Journal Articles

Fibroblast Growth Factor 21 Mediates Specific Glucagon Actions

Kirk M. Habegger, Kerstin Stemmer, Christine Cheng, Timo D. Müller, Kristy M. Heppner, Nickki Ottaway, Jenna Holland, Jazzminn L. Hembree, David Smiley, Vasily Gelfanov, Radha Krishna, Ayman M. Arafat, Anish Konkar, Sara Belli, Martin Kapps, Stephen C. Woods, Susanna M. Hofmann, David D’Alessio, Paul T. Pfluger, Diego Perez-Tilve, Randy J. Seeley, Morichika Konishi, Nobuyujki Itoh, Alexei Kharitonenkov, Joachim Spranger, Richard D. DiMarchi, Matthias H. Tschöp
Journal: Diabetes
Diabetes 2013;62(5):1453–1463
https://doi.org/10.2337/db12-1116
Published: 16 April 2013
View article titled, Fibroblast Growth Factor 21 Mediates Specific Glucagon Actions
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Includes: Supplementary data
Journal Articles

Caloric Restriction Chronically Impairs Metabolic Programming in Mice

Henriette Kirchner, Susanna M. Hofmann, Antje Fischer-Rosinský, Jazzminn Hembree, William Abplanalp, Nickki Ottaway, Elizabeth Donelan, Radha Krishna, Stephen C. Woods, Timo D. Müller, Joachim Spranger, Diego Perez-Tilve, Paul T. Pfluger, Matthias H. Tschöp, Kirk M. Habegger
Journal: Diabetes
Diabetes 2012;61(11):2734–2742
https://doi.org/10.2337/db11-1621
Published: 16 October 2012
View article titled, Caloric Restriction Chronically Impairs Metabolic Programming in Mice
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Includes: Supplementary data
Journal Articles

Direct Control of Brown Adipose Tissue Thermogenesis by Central Nervous System Glucagon-Like Peptide-1 Receptor Signaling

Sarah H. Lockie, Kristy M. Heppner, Nilika Chaudhary, Joseph R. Chabenne, Donald A. Morgan, Christelle Veyrat-Durebex, Gayathri Ananthakrishnan, Françoise Rohner-Jeanrenaud, Daniel J. Drucker, Richard DiMarchi, Kamal Rahmouni, Brian J. Oldfield, Matthias H. Tschöp, Diego Perez-Tilve
Journal: Diabetes
Diabetes 2012;61(11):2753–2762
https://doi.org/10.2337/db11-1556
Published: 16 October 2012
View article titled, Direct Control of Brown Adipose Tissue Thermogenesis by Central Nervous System Glucagon-Like Peptide-1 Receptor Signaling
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Journal Articles

Defective Lipid Delivery Modulates Glucose Tolerance and Metabolic Response to Diet in Apolipoprotein E–Deficient Mice

Susanna M. Hofmann, Diego Perez-Tilve, Todd M. Greer, Beth A. Coburn, Erin Grant, Joshua E. Basford, Matthias H. Tschöp, David Y. Hui
Journal: Diabetes
Diabetes 2008;57(1):5–12
https://doi.org/10.2337/db07-0403
Published: 01 January 2008
View article titled, Defective Lipid Delivery Modulates Glucose Tolerance and Metabolic Response to Diet in Apolipoprotein E–Deficient Mice
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Includes: Supplementary data