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Meeting Abstracts

1733-P: Foxo3 and Heterogeneity of Dedifferentiating ß-Cells

JINSOOK SON, DOMENICO ACCILI
Journal: Diabetes
Diabetes 2024;73(Supplement_1):1733-P
https://doi.org/10.2337/db24-1733-P
Published: 14 June 2024
View article titled, 1733-P: Foxo3 and Heterogeneity of Dedifferentiating ß-Cells
Journal Articles

MAD2-Dependent Insulin Receptor Endocytosis Regulates Metabolic Homeostasis

Junhee Park, Catherine Hall, Brandon Hubbard, Traci LaMoia, Rafael Gaspar, Ali Nasiri, Fang Li, Hanrui Zhang, Jiyeon Kim, Rebecca A. Haeusler, Domenico Accili, Gerald I. Shulman, Hongtao Yu, Eunhee Choi
Journal: Diabetes
Diabetes 2023;72(12):1781–1794
https://doi.org/10.2337/db23-0314
Published: 19 September 2023
View article titled, MAD2-Dependent Insulin Receptor Endocytosis Regulates Metabolic Homeostasis
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Journal Articles

Susumu Seino, MD, DMSci (1948–2021): A Pioneer in the Biology of Insulin Secretion

Domenico Accili, Graeme I. Bell, Bernard Thorens
Journal: Diabetes
Diabetes 2022;71(12):2490–2495
https://doi.org/10.2337/dbi22-0011
Published: 21 November 2022
View article titled, Susumu Seino, MD, DMSci (1948–2021): A Pioneer in the Biology of Insulin Secretion
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Meeting Abstracts

368-OR: Activation of a Yap1-Dependent Mesenchymal Program Promotes ß-Cell Failure

WENDY MCKIMPSON, NEHAN HOQUE, JINSOOK SON, APRIL Y. LEE, DOMENICO ACCILI
Journal: Diabetes
Diabetes 2022;71(Supplement_1):368-OR
https://doi.org/10.2337/db22-368-OR
Published: 01 June 2022
View article titled, 368-OR: Activation of a Yap1-Dependent Mesenchymal Program Promotes ß-Cell Failure
Meeting Abstracts

2071-P: C2CD4A, Pancreatic Beta-Cell Function, and Type 2 Diabetes Susceptibility

TAIYI KUO, DOMENICO ACCILI
Journal: Diabetes
Diabetes 2020;69(Supplement_1):2071-P
https://doi.org/10.2337/db20-2071-P
Published: 01 June 2020
View article titled, 2071-P: C2CD4A, Pancreatic Beta-Cell Function, and Type 2 Diabetes Susceptibility
Journal Articles

PPARγ Deacetylation Confers the Antiatherogenic Effect and Improves Endothelial Function in Diabetes Treatment

Longhua Liu, Lihong Fan, Michelle Chan, Michael J. Kraakman, Jing Yang, Yong Fan, Nicole Aaron, Qianfen Wan, Maria Alicia Carrillo-Sepulveda, Alan R. Tall, Ira Tabas, Domenico Accili, Li Qiang
Journal: Diabetes
Diabetes 2020;69(8):1793–1803
https://doi.org/10.2337/db20-0217
Published: 14 May 2020
View article titled, PPARγ Deacetylation Confers the Antiatherogenic Effect and Improves Endothelial Function in Diabetes Treatment
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Journal Articles

Identification of Insulin-Responsive Transcription Factors That Regulate Glucose Production by Hepatocytes

Liheng Wang, Qiongming Liu, Takumi Kitamoto, Junjie Hou, Jun Qin, Domenico Accili
Journal: Diabetes
Diabetes 2019;68(6):1156–1167
https://doi.org/10.2337/db18-1236
Published: 01 April 2019
View article titled, Identification of Insulin-Responsive Transcription Factors That Regulate Glucose Production by Hepatocytes
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Includes: Supplementary data
Journal Articles

Insulin Action Research and the Future of Diabetes Treatment: The 2017 Banting Medal for Scientific Achievement Lecture

Domenico Accili
Journal: Diabetes
Diabetes 2018;67(9):1701–1709
https://doi.org/10.2337/dbi18-0025
Published: 15 August 2018
View article titled, Insulin Action Research and the Future of Diabetes Treatment: The 2017 Banting Medal for Scientific Achievement Lecture
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Meeting Abstracts

Foxo1-Expressing Cells in the Gut as a Source of Insulin for Diabetes Treatment

WENDY MCKIMPSON, TAIYI KUO, DOMENICO ACCILI
Journal: Diabetes
Diabetes 2018;67(Supplement_1):324-OR
https://doi.org/10.2337/db18-324-OR
Published: 01 July 2018
View article titled, Foxo1-Expressing Cells in the Gut as a Source of Insulin for Diabetes Treatment
Meeting Abstracts

The Increment of Noradrenergic Fibers Correlates with the Density of Dedifferentiated ß Cells in Humans

FRANCESCA CINTI, ILENIA SEVERI, MARA SULEIMAN, LORELLA MARSELLI, PIERO MARCHETTI, SAVERIO CINTI, DOMENICO ACCILI
Journal: Diabetes
Diabetes 2018;67(Supplement_1):2142-P
https://doi.org/10.2337/db18-2142-P
Published: 01 July 2018
View article titled, The Increment of Noradrenergic Fibers Correlates with the Density of Dedifferentiated ß Cells in Humans
Journal Articles

Expression of Concern. The IR1152 Mutant Insulin Receptor Selectively Impairs Insulin Action in Skeletal Muscle but Not in Liver. Diabetes 2000;49: 1194–1202 . DOI: 10.2337/diabetes.49.7.1194. PMID: 10909978

Matilde Caruso, Claudia Miele, Andrea Oliva, Gerolama Condorelli, Francesco Oriente, Gabriele Riccardi, Brunella Capaldo, Francesca Fiory, Domenico Accili, Pietro Formisano, Francesco Beguinot
Journal: Diabetes
Diabetes 2018;67(2):345
https://doi.org/10.2337/db17-ec2017a
Published: 06 November 2017
View article titled, Expression of Concern. The IR<sub>1152</sub> Mutant Insulin Receptor Selectively Impairs Insulin Action in Skeletal Muscle but Not in Liver. Diabetes 2000;49: 1194–1202 . DOI: 10.2337/diabetes.49.7.1194. PMID: 10909978
Open the PDF for Expression of Concern. The IR<sub>1152</sub> Mutant Insulin Receptor Selectively Impairs Insulin Action in Skeletal Muscle but Not in Liver. Diabetes 2000;49: 1194–1202 . DOI: 10.2337/diabetes.49.7.1194. PMID: 10909978 in another window
Journal Articles

Pair Feeding, but Not Insulin, Phloridzin, or Rosiglitazone Treatment, Curtails Markers of β-Cell Dedifferentiation in db/db Mice

Emi Ishida, Ja Young Kim-Muller, Domenico Accili
Journal: Diabetes
Diabetes 2017;66(8):2092–2101
https://doi.org/10.2337/db16-1213
Published: 15 May 2017
View article titled, Pair Feeding, but Not Insulin, Phloridzin, or Rosiglitazone Treatment, Curtails Markers of β-Cell Dedifferentiation in <em>db/db</em> Mice
Open the PDF for Pair Feeding, but Not Insulin, Phloridzin, or Rosiglitazone Treatment, Curtails Markers of β-Cell Dedifferentiation in <em>db/db</em> Mice in another window
Includes: Supplementary data
Journal Articles

Disruption of Adipose Rab10-Dependent Insulin Signaling Causes Hepatic Insulin Resistance

Reema P. Vazirani, Akanksha Verma, L. Amanda Sadacca, Melanie S. Buckman, Belen Picatoste, Muheeb Beg, Christopher Torsitano, Joanne H. Bruno, Rajesh T. Patel, Kotryna Simonyte, Joao P. Camporez, Gabriela Moreira, Domenick J. Falcone, Domenico Accili, Olivier Elemento, Gerald I. Shulman, Barbara B. Kahn, Timothy E. McGraw
Journal: Diabetes
Diabetes 2016;65(6):1577–1589
https://doi.org/10.2337/db15-1128
Published: 25 March 2016
View article titled, Disruption of Adipose Rab10-Dependent Insulin Signaling Causes Hepatic Insulin Resistance
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Includes: Supplementary data
Journal Articles

Gpr17 in AgRP Neurons Regulates Feeding and Sensitivity to Insulin and Leptin

Hongxia Ren, Joshua R. Cook, Ning Kon, Domenico Accili
Journal: Diabetes
Diabetes 2015;64(11):3670–3679
https://doi.org/10.2337/db15-0390
Published: 15 July 2015
View article titled, Gpr17 in AgRP Neurons Regulates Feeding and Sensitivity to Insulin and Leptin
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Includes: Supplementary data
Journal Articles

Legacy Effect of Foxo1 in Pancreatic Endocrine Progenitors on Adult β-Cell Mass and Function

Shivatra Chutima Talchai, Domenico Accili
Journal: Diabetes
Diabetes 2015;64(8):2868–2879
https://doi.org/10.2337/db14-1696
Published: 17 March 2015
View article titled, Legacy Effect of Foxo1 in Pancreatic Endocrine Progenitors on Adult β-Cell Mass and Function
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Includes: Supplementary data
Journal Articles

A Mutant Allele Encoding DNA Binding–Deficient FoxO1 Differentially Regulates Hepatic Glucose and Lipid Metabolism

Joshua R. Cook, Michihiro Matsumoto, Alexander S. Banks, Tadahiro Kitamura, Kyoichiro Tsuchiya, Domenico Accili
Journal: Diabetes
Diabetes 2015;64(6):1951–1965
https://doi.org/10.2337/db14-1506
Published: 09 January 2015
View article titled, A Mutant Allele Encoding DNA Binding–Deficient FoxO1 Differentially Regulates Hepatic Glucose and Lipid Metabolism
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Journal Articles

Anorexia and Impaired Glucose Metabolism in Mice With Hypothalamic Ablation of Glut4 Neurons

Hongxia Ren, Taylor Y. Lu, Timothy E. McGraw, Domenico Accili
Journal: Diabetes
Diabetes 2015;64(2):405–417
https://doi.org/10.2337/db14-0752
Published: 02 September 2014
View article titled, Anorexia and Impaired Glucose Metabolism in Mice With Hypothalamic Ablation of Glut4 Neurons
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Includes: Supplementary data
Journal Articles

Preserved Energy Balance in Mice Lacking FoxO1 in Neurons of Nkx2.1 Lineage Reveals Functional Heterogeneity of FoxO1 Signaling Within the Hypothalamus

Garrett Heinrich, Kana Meece, Sharon L. Wardlaw, Domenico Accili
Journal: Diabetes
Diabetes 2014;63(5):1572–1582
https://doi.org/10.2337/db13-0651
Published: 12 April 2014
View article titled, Preserved Energy Balance in Mice Lacking FoxO1 in Neurons of Nkx2.1 Lineage Reveals Functional Heterogeneity of FoxO1 Signaling Within the Hypothalamus
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Includes: Supplementary data
Journal Articles

Human Insulin Resistance Is Associated With Increased Plasma Levels of 12α-Hydroxylated Bile Acids

Rebecca A. Haeusler, Brenno Astiarraga, Stefania Camastra, Domenico Accili, Ele Ferrannini
Journal: Diabetes
Diabetes 2013;62(12):4184–4191
https://doi.org/10.2337/db13-0639
Published: 16 November 2013
View article titled, Human Insulin Resistance Is Associated With Increased Plasma Levels of 12α-Hydroxylated Bile Acids
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Includes: Supplementary data
Journal Articles

Blunted Refeeding Response and Increased Locomotor Activity in Mice Lacking FoxO1 in Synapsin-Cre–Expressing Neurons

Hongxia Ren, Leona Plum-Morschel, Roger Gutierrez-Juarez, Taylor Y. Lu, Ja Young Kim-Muller, Garrett Heinrich, Sharon L. Wardlaw, Rae Silver, Domenico Accili
Journal: Diabetes
Diabetes 2013;62(10):3373–3383
https://doi.org/10.2337/db13-0597
Published: 17 September 2013
View article titled, Blunted Refeeding Response and Increased Locomotor Activity in Mice Lacking FoxO1 in Synapsin-<em>Cre</em>–Expressing Neurons
Open the PDF for Blunted Refeeding Response and Increased Locomotor Activity in Mice Lacking FoxO1 in Synapsin-<em>Cre</em>–Expressing Neurons in another window