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Journal Articles

Insulin Delivery Into the Peripheral Circulation: A Key Contributor to Hypoglycemia in Type 1 Diabetes

Justin M. Gregory, Guillaume Kraft, Melanie F. Scott, Doss W. Neal, Ben Farmer, Marta S. Smith, Jon R. Hastings, Eric J. Allen, E. Patrick Donahue, Noelia Rivera, Jason J. Winnick, Dale S. Edgerton, Erica Nishimura, Christian Fledelius, Christian L. Brand, Alan D. Cherrington

Diabetes 2015;64(10):3439–3451

https://doi.org/10.2337/db15-0071

Published: 17 June 2015

View article titled, Insulin Delivery Into the Peripheral Circulation: A Key Contributor to Hypoglycemia in Type 1 Diabetes

Journal Articles

Portal Vein Glucose Entry Triggers a Coordinated Cellular Response That Potentiates Hepatic Glucose Uptake and Storage in Normal but Not High-Fat/High-Fructose–Fed Dogs

Katie C. Coate, Guillaume Kraft, Jose M. Irimia, Marta S. Smith, Ben Farmer, Doss W. Neal, Peter J. Roach, Masakazu Shiota, Alan D. Cherrington

Diabetes 2013;62(2):392–400

https://doi.org/10.2337/db12-0417

Published: 17 January 2013

View article titled, Portal Vein Glucose Entry Triggers a Coordinated Cellular Response That Potentiates Hepatic Glucose Uptake and Storage in Normal but Not High-Fat/High-Fructose–Fed Dogs

Includes: Supplementary data

Journal Articles

Hepatic Glycogen Supercompensation Activates AMP-Activated Protein Kinase, Impairs Insulin Signaling, and Reduces Glycogen Deposition in the Liver

Jason J. Winnick, Zhibo An, Christopher J. Ramnanan, Marta Smith, Jose M. Irimia, Doss W. Neal, Mary Courtney Moore, Peter J. Roach, Alan D. Cherrington

Diabetes 2011;60(2):398–407

https://doi.org/10.2337/db10-0592

Published: 21 January 2011

View article titled, Hepatic Glycogen Supercompensation Activates AMP-Activated Protein Kinase, Impairs Insulin Signaling, and Reduces Glycogen Deposition in the Liver

Journal Articles

Molecular Characterization of Insulin-Mediated Suppression of Hepatic Glucose Production In Vivo

Christopher J. Ramnanan, Dale S. Edgerton, Noelia Rivera, Jose Irimia-Dominguez, Ben Farmer, Doss W. Neal, Margaret Lautz, E. Patrick Donahue, Catalina M. Meyer, Peter J. Roach, Alan D. Cherrington

Diabetes 2010;59(6):1302–1311

https://doi.org/10.2337/db09-1625

Published: 25 February 2010

View article titled, Molecular Characterization of Insulin-Mediated Suppression of Hepatic Glucose Production In Vivo

Includes: Supplementary data

Journal Articles

Effects of Insulin on the Metabolic Control of Hepatic Gluconeogenesis In Vivo

Dale S. Edgerton, Christopher J. Ramnanan, Carrie A. Grueter, Kathryn M.S. Johnson, Margaret Lautz, Doss W. Neal, Phillip E. Williams, Alan D. Cherrington

Diabetes 2009;58(12):2766–2775

https://doi.org/10.2337/db09-0328

Published: 15 September 2009

View article titled, Effects of Insulin on the Metabolic Control of Hepatic Gluconeogenesis In Vivo

Includes: Supplementary data

Journal Articles

Inhibition of Dipeptidyl Peptidase-4 by Vildagliptin During Glucagon-Like Peptide 1 Infusion Increases Liver Glucose Uptake in the Conscious Dog

Dale S. Edgerton, Kathryn M.S. Johnson, Doss W. Neal, Melanie Scott, Charles H. Hobbs, Xia Zhang, Alokesh Duttaroy, Alan D. Cherrington

Diabetes 2009;58(1):243–249

https://doi.org/10.2337/db08-0515

Published: 01 January 2009

View article titled, Inhibition of Dipeptidyl Peptidase-4 by Vildagliptin During Glucagon-Like Peptide 1 Infusion Increases Liver Glucose Uptake in the Conscious Dog

Journal Articles

Inhalation of Human Insulin (Exubera) Augments the Efficiency of Muscle Glucose Uptake In Vivo

Dale S. Edgerton, Alan D. Cherrington, Phillip Williams, Doss W. Neal, Melanie Scott, Larry Bowen, Warren Wilson, Charles H. Hobbs, Chet Leach, Mei-chang Kuo, Thomas R. Strack

Diabetes 2006;55(12):3604–3610

https://doi.org/10.2337/db06-0718

Published: 01 December 2006

View article titled, Inhalation of Human Insulin (Exubera) Augments the Efficiency of Muscle Glucose Uptake In Vivo

Journal Articles

Inhalation of Insulin (Exubera) Is Associated With Augmented Disposal of Portally Infused Glucose in Dogs

Dale S. Edgerton, Doss W. Neal, Melanie Scott, Larry Bowen, Warren Wilson, Charles H. Hobbs, Chet Leach, Shantha Sivakumaran, Thomas R. Strack, Alan D. Cherrington

Diabetes 2005;54(4):1164–1170

https://doi.org/10.2337/diabetes.54.4.1164

Published: 01 April 2005

View article titled, Inhalation of Insulin (Exubera) Is Associated With Augmented Disposal of Portally Infused Glucose in Dogs

Journal Articles

Inhalation of Insulin in Dogs: Assessment of Insulin Levels and Comparison to Subcutaneous Injection

Alan D. Cherrington, Doss W. Neal, Dale S. Edgerton, Dana Glass, Larry Bowen, Charles H. Hobbs, Chet Leach, Ralf Rosskamp, Thomas R. Strack

Diabetes 2004;53(4):877–881

https://doi.org/10.2337/diabetes.53.4.877

Published: 01 April 2004

View article titled, Inhalation of Insulin in Dogs: <subtitle>Assessment of Insulin Levels and Comparison to Subcutaneous Injection</subtitle>

Journal Articles

Nonesterified Fatty Acids and Hepatic Glucose Metabolism in the Conscious Dog

Mary Courtney Moore, Shosuke Satake, Margaret Lautz, Scott A. Soleimanpour, Doss W. Neal, Marta Smith, Alan D. Cherrington

Diabetes 2004;53(1):32–40

https://doi.org/10.2337/diabetes.53.1.32

Published: 01 January 2004

View article titled, Nonesterified Fatty Acids and Hepatic Glucose Metabolism in the Conscious Dog

Journal Articles

Portal Serotonin Infusion and Glucose Disposal in Conscious Dogs

Mary Courtney Moore, W. Blair Geho, Margaret Lautz, Ben Farmer, Doss W. Neal, Alan D. Cherrington

Diabetes 2004;53(1):14–20

https://doi.org/10.2337/diabetes.53.1.14

Published: 01 January 2004

View article titled, Portal Serotonin Infusion and Glucose Disposal in Conscious Dogs

Journal Articles

Insulin Sensitively Controls the Glucagon Response to Mild Hypoglycemia in the Dog

Kayano Igawa, Mike Mugavero, Masakazu Shiota, Doss W. Neal, Alan D. Cherrington

Diabetes 2002;51(10):3033–3042

https://doi.org/10.2337/diabetes.51.10.3033

Published: 01 October 2002

View article titled, Insulin Sensitively Controls the Glucagon Response to Mild Hypoglycemia in the Dog

Journal Articles

Direct and Indirect Effects of Insulin on Glucose Uptake and Storage by the Liver

Shosuke Satake, Mary Courtney Moore, Kayano Igawa, Margaret Converse, Benjamin Farmer, Doss W. Neal, Alan D. Cherrington

Diabetes 2002;51(6):1663–1671

https://doi.org/10.2337/diabetes.51.6.1663

Published: 01 June 2002

View article titled, Direct and Indirect Effects of Insulin on Glucose Uptake and Storage by the Liver

Journal Articles

Inclusion of Low Amounts of Fructose With an Intraduodenal Glucose Load Markedly Reduces Postprandial Hyperglycemia and Hyperinsulinemia in the Conscious Dog

Masakazu Shiota, Mary Courtney Moore, Pietro Galassetti, Michael Monohan, Doss W. Neal, Gerald I. Shulman, Alan D. Cherrington

Diabetes 2002;51(2):469–478

https://doi.org/10.2337/diabetes.51.2.469

Published: 01 February 2002

View article titled, Inclusion of Low Amounts of Fructose With an Intraduodenal Glucose Load Markedly Reduces Postprandial Hyperglycemia and Hyperinsulinemia in the Conscious Dog

Journal Articles

Pancreatic Response to Mild Non–Insulin-Induced Hypoglycemia Does Not Involve Extrinsic Neural Input

Stephanie M. Sherck, Masakazu Shiota, James Saccomando, Sylvain Cardin, Eric J. Allen, Jon R. Hastings, Doss W. Neal, Phil E. Williams, Alan D. Cherrington

Diabetes 2001;50(11):2487–2496

https://doi.org/10.2337/diabetes.50.11.2487

Published: 01 November 2001

View article titled, Pancreatic Response to Mild Non–Insulin-Induced Hypoglycemia Does Not Involve Extrinsic Neural Input

Journal Articles

Effect of Vagal Cooling on the Counterregulatory Response to Hypoglycemia Induced by a Low Dose of Insulin in the Conscious Dog

Sylvain Cardin, Patricia A. Jackson, Dale S. Edgerton, Doss W. Neal, Christopher S. Coffey, Alan D. Cherrington

Diabetes 2001;50(3):558–564

https://doi.org/10.2337/diabetes.50.3.558

Published: 01 March 2001

View article titled, Effect of Vagal Cooling on the Counterregulatory Response to Hypoglycemia Induced by a Low Dose of Insulin in the Conscious Dog

Journal Articles

α- and β-Cell Responses to Small Changes in Plasma Glucose in the Conscious Dog

Nancy Flattem, Kayano Igawa, Masakazu Shiota, Maya G. Emshwiller, Doss W. Neal, Alan D. Cherrington

Diabetes 2001;50(2):367–375

https://doi.org/10.2337/diabetes.50.2.367

Published: 01 February 2001

View article titled, α- and β-Cell Responses to Small Changes in Plasma Glucose in the Conscious Dog

Journal Articles

The Role of Fatty Acids in Mediating the Effects of Peripheral Insulin on Hepatic Glucose Production in the Conscious Dog

Dana K Sindelar, Chang A Chu, Michelle Rohlie, Doss W Neal, Larry L Swift, Alan D Cherrington

Diabetes 1997;46(2):187–196

https://doi.org/10.2337/diab.46.2.187

Published: 01 February 1997

View article titled, The Role of Fatty Acids in Mediating the Effects of Peripheral Insulin on Hepatic Glucose Production in the Conscious Dog

Journal Articles

In the Absence of Counterregulatory Hormones, the Increase in Hepatic Glucose Production During Insulin-Induced Hypoglycemia in the Dog Is Initiated in the Liver Rather Than the Brain

Cynthia C Connolly, Sharon R Myers, Doss W Neal, Jon R Hastings, Alan D Cherrington

Diabetes 1996;45(12):1805–1813

https://doi.org/10.2337/diab.45.12.1805

Published: 01 December 1996

View article titled, In the Absence of Counterregulatory Hormones, the Increase in Hepatic Glucose Production During Insulin-Induced Hypoglycemia in the Dog Is Initiated in the Liver Rather Than the Brain

Journal Articles

A Comparison of the Effects of Selective Increases in Peripheral or Portal insulin on Hepatic Glucose Production in the Conscious Dog

Dana K Sindelar, James H Balcom, Chang A Chu, Doss W Neal, Alan D Cherrington

Diabetes 1996;45(11):1594–1604

https://doi.org/10.2337/diab.45.11.1594

Published: 01 November 1996

View article titled, A Comparison of the Effects of Selective Increases in Peripheral or Portal insulin on Hepatic Glucose Production in the Conscious Dog

NARROW

Insulin Delivery Into the Peripheral Circulation: A Key Contributor to Hypoglycemia in Type 1 Diabetes

Portal Vein Glucose Entry Triggers a Coordinated Cellular Response That Potentiates Hepatic Glucose Uptake and Storage in Normal but Not High-Fat/High-Fructose–Fed Dogs

Hepatic Glycogen Supercompensation Activates AMP-Activated Protein Kinase, Impairs Insulin Signaling, and Reduces Glycogen Deposition in the Liver

Molecular Characterization of Insulin-Mediated Suppression of Hepatic Glucose Production In Vivo

Effects of Insulin on the Metabolic Control of Hepatic Gluconeogenesis In Vivo

Inhibition of Dipeptidyl Peptidase-4 by Vildagliptin During Glucagon-Like Peptide 1 Infusion Increases Liver Glucose Uptake in the Conscious Dog

Inhalation of Human Insulin (Exubera) Augments the Efficiency of Muscle Glucose Uptake In Vivo

Inhalation of Insulin (Exubera) Is Associated With Augmented Disposal of Portally Infused Glucose in Dogs

Inhalation of Insulin in Dogs: Assessment of Insulin Levels and Comparison to Subcutaneous Injection

Nonesterified Fatty Acids and Hepatic Glucose Metabolism in the Conscious Dog

Portal Serotonin Infusion and Glucose Disposal in Conscious Dogs

Insulin Sensitively Controls the Glucagon Response to Mild Hypoglycemia in the Dog

Direct and Indirect Effects of Insulin on Glucose Uptake and Storage by the Liver

Inclusion of Low Amounts of Fructose With an Intraduodenal Glucose Load Markedly Reduces Postprandial Hyperglycemia and Hyperinsulinemia in the Conscious Dog

Pancreatic Response to Mild Non–Insulin-Induced Hypoglycemia Does Not Involve Extrinsic Neural Input

Effect of Vagal Cooling on the Counterregulatory Response to Hypoglycemia Induced by a Low Dose of Insulin in the Conscious Dog

α- and β-Cell Responses to Small Changes in Plasma Glucose in the Conscious Dog

The Role of Fatty Acids in Mediating the Effects of Peripheral Insulin on Hepatic Glucose Production in the Conscious Dog

In the Absence of Counterregulatory Hormones, the Increase in Hepatic Glucose Production During Insulin-Induced Hypoglycemia in the Dog Is Initiated in the Liver Rather Than the Brain

A Comparison of the Effects of Selective Increases in Peripheral or Portal insulin on Hepatic Glucose Production in the Conscious Dog

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