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E. Dale Abel
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Journal Articles

Mitochondrial Dynamics, Diabetes, and Cardiovascular Disease

Free
Luis Miguel García-Peña, E. Dale Abel, Renata O. Pereira
Journal: Diabetes
Diabetes 2024;73(2):151–161
https://doi.org/10.2337/dbi23-0003
Published: 19 January 2024
View articletitled, Mitochondrial Dynamics, Diabetes, and Cardiovascular Disease
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Journal Articles

OPA1 Regulates Lipid Metabolism and Cold-Induced Browning of White Adipose Tissue in Mice

Free
Renata O. Pereira, Angela C. Olvera, Alex Marti, Shi Fang, Jeffrey R. White, Michael Westphal, Rana Hewezi, Salma T. AshShareef, Luis Miguel García-Peña, Jivan Koneru, Matthew J. Potthoff, E. Dale Abel
Journal: Diabetes
Diabetes 2022;71(12):2572–2583
https://doi.org/10.2337/db22-0450
Published: 28 September 2022
View articletitled, OPA1 Regulates Lipid Metabolism and Cold-Induced Browning of White Adipose Tissue in Mice
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Journal Articles

Maintaining Myocardial Glucose Utilization in Diabetic Cardiomyopathy Accelerates Mitochondrial Dysfunction

Free
Adam R. Wende, John C. Schell, Chae-Myeong Ha, Mark E. Pepin, Oleh Khalimonchuk, Hansjörg Schwertz, Renata O. Pereira, Manoja K. Brahma, Joseph Tuinei, Ariel Contreras-Ferrat, Li Wang, Chase A. Andrizzi, Curtis D. Olsen, Wayne E. Bradley, Louis J. Dell’Italia, Wolfgang H. Dillmann, Sheldon E. Litwin, E. Dale Abel
Journal: Diabetes
Diabetes 2020;69(10):2094–2111
https://doi.org/10.2337/db19-1057
Published: 04 May 2020
View articletitled, Maintaining Myocardial Glucose Utilization in Diabetic Cardiomyopathy Accelerates Mitochondrial Dysfunction
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Meeting Abstracts

1984-P: Optic Atrophy 1 Deletion in Brown Adipose Tissue Induces Browning of White Fat by Inducing FGF-21

Free
RENATA PEREIRA ALAMBERT, SATYA MURTHY TADINADA, E. DALE ABEL
Journal: Diabetes
Diabetes 2019;68(Supplement_1):1984-P
https://doi.org/10.2337/db19-1984-P
Published: 01 June 2019
View articletitled, 1984-P: Optic Atrophy 1 Deletion in Brown Adipose Tissue Induces Browning of White Fat by Inducing FGF-21
Journal Articles

Glucose Metabolism Is Required for Platelet Hyperactivation in a Murine Model of Type 1 Diabetes

Free
Trevor P. Fidler, Alex Marti, Katelyn Gerth, Elizabeth A. Middleton, Robert A. Campbell, Matthew T. Rondina, Andrew S. Weyrich, E. Dale Abel
Journal: Diabetes
Diabetes 2019;68(5):932–938
https://doi.org/10.2337/db18-0981
Published: 14 February 2019
View articletitled, Glucose Metabolism Is Required for Platelet Hyperactivation in a Murine Model of Type 1 Diabetes
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Includes: Supplementary data
Meeting Abstracts

Sex Differences in the Response of C57BL/6 Mice to Ketogenic Diets

Free
JESSE COCHRAN, PAUL V. TAUFALELE, KEVIN D. LIN, YUAN ZHANG, E. DALE ABEL
Journal: Diabetes
Diabetes 2018;67(Supplement_1):1884-P
https://doi.org/10.2337/db18-1884-P
Published: 01 July 2018
View articletitled, Sex Differences in the Response of C57BL/6 Mice to Ketogenic Diets
Meeting Abstracts

Regulation of Hepatic Insulin Sensitivity and Hepatic Steatosis by ULK1

Free
YOUNGDO KOO, MICHAEL P. GARNEAU, QUANJIANG ZHANG, E. DALE ABEL
Journal: Diabetes
Diabetes 2018;67(Supplement_1):1863-P
https://doi.org/10.2337/db18-1863-P
Published: 01 July 2018
View articletitled, Regulation of Hepatic Insulin Sensitivity and Hepatic Steatosis by ULK1
Meeting Abstracts

Resistance to Diet-Induced Obesity in Mice Lacking OPA1 in Adipose Tissue Occurs Independently of Fat-Derived FGF-21 and BAT Function

Free
RENATA PEREIRA, ANGELA C. OLVERA, ALEX A. MARTI, RANA HEWEZI, WILLIAM A. BUI TRAN, MATTHEW J. POTTHOFF, E. DALE ABEL
Journal: Diabetes
Diabetes 2018;67(Supplement_1):276-LB
https://doi.org/10.2337/db18-276-LB
Published: 01 July 2018
View articletitled, Resistance to Diet-Induced Obesity in Mice Lacking OPA1 in Adipose Tissue Occurs Independently of Fat-Derived FGF-21 and BAT Function
Journal Articles

Mitochondrial Calpain-1 Disrupts ATP Synthase and Induces Superoxide Generation in Type 1 Diabetic Hearts: A Novel Mechanism Contributing to Diabetic Cardiomyopathy

Free
Rui Ni, Dong Zheng, Sidong Xiong, David J. Hill, Tao Sun, Richard B. Gardiner, Guo-Chang Fan, Yanrong Lu, E. Dale Abel, Peter A. Greer, Tianqing Peng
Journal: Diabetes
Diabetes 2016;65(1):255–268
https://doi.org/10.2337/db15-0963
Published: 15 October 2015
View articletitled, Mitochondrial Calpain-1 Disrupts ATP Synthase and Induces Superoxide Generation in Type 1 Diabetic Hearts: A Novel Mechanism Contributing to Diabetic Cardiomyopathy
Open the PDF for Mitochondrial Calpain-1 Disrupts ATP Synthase and Induces Superoxide Generation in Type 1 Diabetic Hearts: A Novel Mechanism Contributing to Diabetic Cardiomyopathy in another window
Includes: Supplementary data
Journal Articles

Ceramide-Initiated Protein Phosphatase 2A Activation Contributes to Arterial Dysfunction In Vivo

Free
Leena P. Bharath, Ting Ruan, Youyou Li, Anindita Ravindran, Xin Wan, Jennifer Kim Nhan, Matthew Lewis Walker, Lance Deeter, Rebekah Goodrich, Elizabeth Johnson, Derek Munday, Robert Mueller, David Kunz, Deborah Jones, Van Reese, Scott A. Summers, Pon Velayutham Anandh Babu, William L. Holland, Quan-Jiang Zhang, E. Dale Abel, J. David Symons
Journal: Diabetes
Diabetes 2015;64(11):3914–3926
https://doi.org/10.2337/db15-0244
Published: 07 August 2015
View articletitled, Ceramide-Initiated Protein Phosphatase 2A Activation Contributes to Arterial Dysfunction In Vivo
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Includes: Supplementary data
Journal Articles

Insulin Inhibits Cardiac Contractility by Inducing a Gi-Biased β2-Adrenergic Signaling in Hearts

Free
Qin Fu, Bing Xu, Yongming Liu, Dippal Parikh, Jing Li, Ying Li, Yuan Zhang, Christian Riehle, Yi Zhu, Tenley Rawlings, Qian Shi, Richard B. Clark, Xiongwen Chen, E. Dale Abel, Yang K. Xiang
Journal: Diabetes
Diabetes 2014;63(8):2676–2689
https://doi.org/10.2337/db13-1763
Published: 17 July 2014
View articletitled, Insulin Inhibits Cardiac Contractility by Inducing a Gi-Biased β2-Adrenergic Signaling in Hearts
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Includes: Supplementary data
Journal Articles

Time to Look Back and to Look Forward

Open Access
K. Sreekumaran Nair, E. Dale Abel, Sharon G. Adler, Peter J. Dyck, Thomas W. Gardner, Kathryn M. Haskins, Gökhan Hotamisligil, Michael D. Jensen, Anna Krook, Lawrence J. Mandarino, Braxton D. Mitchell, Jeffrey E. Pessin, James R. Sowers, Lori Sussel, Nick Wareham, Adrian Vella
Journal: Diabetes
Diabetes 2014;63(4):1169–1170
https://doi.org/10.2337/db14-0067
Published: 13 March 2014
View articletitled, Time to Look Back and to Look Forward
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Journal Articles

Podocyte-Specific GLUT4-Deficient Mice Have Fewer and Larger Podocytes and Are Protected From Diabetic Nephropathy

Open Access
Johanna Guzman, Alexandra N. Jauregui, Sandra Merscher-Gomez, Dony Maiguel, Cristina Muresan, Alla Mitrofanova, Ana Diez-Sampedro, Joel Szust, Tae-Hyun Yoo, Rodrigo Villarreal, Christopher Pedigo, R. Damaris Molano, Kevin Johnson, Barbara Kahn, Bjoern Hartleben, Tobias B. Huber, Jharna Saha, George W. Burke, III, E. Dale Abel, Frank C. Brosius, Alessia Fornoni
Journal: Diabetes
Diabetes 2014;63(2):701–714
https://doi.org/10.2337/db13-0752
Published: 16 January 2014
View articletitled, Podocyte-Specific GLUT4-Deficient Mice Have Fewer and Larger Podocytes and Are Protected From Diabetic Nephropathy
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Includes: Supplementary data
Journal Articles

UCP3 Regulates Cardiac Efficiency and Mitochondrial Coupling in High Fat–Fed Mice but Not in Leptin-Deficient Mice

Open Access
Sihem Boudina, Yong Hwan Han, Shaobo Pei, Timothy J. Tidwell, Brandon Henrie, Joseph Tuinei, Curtis Olsen, Sandra Sena, E. Dale Abel
Journal: Diabetes
Diabetes 2012;61(12):3260–3269
https://doi.org/10.2337/db12-0063
Published: 15 November 2012
View articletitled, UCP3 Regulates Cardiac Efficiency and Mitochondrial Coupling in High Fat–Fed Mice but Not in Leptin-Deficient Mice
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Includes: Supplementary data
Journal Articles

Ceramide Mediates Vascular Dysfunction in Diet-Induced Obesity by PP2A-Mediated Dephosphorylation of the eNOS-Akt Complex

Open Access
Quan-Jiang Zhang, William L. Holland, Lloyd Wilson, Jason M. Tanner, Devin Kearns, Judd M. Cahoon, Dix Pettey, Jason Losee, Bradlee Duncan, Derrick Gale, Christopher A. Kowalski, Nicholas Deeter, Alexandrea Nichols, Michole Deesing, Colton Arrant, Ting Ruan, Christoph Boehme, Dane R. McCamey, Janvida Rou, Kapil Ambal, Krishna K. Narra, Scott A. Summers, E. Dale Abel, J. David Symons
Journal: Diabetes
Diabetes 2012;61(7):1848–1859
https://doi.org/10.2337/db11-1399
Published: 15 June 2012
View articletitled, Ceramide Mediates Vascular Dysfunction in Diet-Induced Obesity by PP2A-Mediated Dephosphorylation of the eNOS-Akt Complex
Open the PDF for Ceramide Mediates Vascular Dysfunction in Diet-Induced Obesity by PP2A-Mediated Dephosphorylation of the eNOS-Akt Complex in another window
Includes: Supplementary data
Journal Articles

Targeted Inhibition of Calpain Reduces Myocardial Hypertrophy and Fibrosis in Mouse Models of Type 1 Diabetes

Open Access
Ying Li, Jian Ma, Huaqing Zhu, Manpreet Singh, David Hill, Peter A. Greer, J. Malcolm Arnold, E. Dale Abel, Tianqing Peng
Journal: Diabetes
Diabetes 2011;60(11):2985–2994
https://doi.org/10.2337/db10-1333
Published: 17 October 2011
View articletitled, Targeted Inhibition of Calpain Reduces Myocardial Hypertrophy and Fibrosis in Mouse Models of Type 1 Diabetes
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Includes: Supplementary data
Journal Articles

Oxidative Phosphorylation Flexibility in the Liver of Mice Resistant to High-Fat Diet–Induced Hepatic Steatosis

Open Access
Carinne Poussin, Mark Ibberson, Diana Hall, Jun Ding, Jamie Soto, E. Dale Abel, Bernard Thorens
Journal: Diabetes
Diabetes 2011;60(9):2216–2224
https://doi.org/10.2337/db11-0338
Published: 20 August 2011
View articletitled, Oxidative Phosphorylation Flexibility in the Liver of Mice Resistant to High-Fat Diet–Induced Hepatic Steatosis
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Includes: Supplementary data
Journal Articles

Central Leptin Signaling Is Required to Normalize Myocardial Fatty Acid Oxidation Rates in Caloric-Restricted ob/ob Mice

Open Access
Crystal Sloan, Joseph Tuinei, Katherine Nemetz, Jonathan Frandsen, Jamie Soto, Noah Wride, Tomoki Sempokuya, Luis Alegria, Heiko Bugger, E. Dale Abel
Journal: Diabetes
Diabetes 2011;60(5):1424–1434
https://doi.org/10.2337/db10-1106
Published: 23 April 2011
View articletitled, Central Leptin Signaling Is Required to Normalize Myocardial Fatty Acid Oxidation Rates in Caloric-Restricted ob/ob Mice
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Includes: Supplementary data
Journal Articles

Iron Overload and Diabetes Risk: A Shift From Glucose to Fatty Acid Oxidation and Increased Hepatic Glucose Production in a Mouse Model of Hereditary Hemochromatosis

Open Access
Jingyu Huang, Deborah Jones, Bai Luo, Michael Sanderson, Jamie Soto, E. Dale Abel, Robert C. Cooksey, Donald A. McClain
Journal: Diabetes
Diabetes 2011;60(1):80–87
https://doi.org/10.2337/db10-0593
Published: 28 September 2010
View articletitled, Iron Overload and Diabetes Risk: A Shift From Glucose to Fatty Acid Oxidation and Increased Hepatic Glucose Production in a Mouse Model of Hereditary Hemochromatosis
Open the PDF for Iron Overload and Diabetes Risk: A Shift From Glucose to Fatty Acid Oxidation and Increased Hepatic Glucose Production in a Mouse Model of Hereditary Hemochromatosis in another window
Journal Articles

Acute Inhibition of Fatty Acid Import Inhibits GLUT4 Transcription in Adipose Tissue, but Not Skeletal or Cardiac Muscle Tissue, Partly Through Liver X Receptor (LXR) Signaling

Open Access
Beth A. Griesel, Juston Weems, Robert A. Russell, E. Dale Abel, Kenneth Humphries, Ann Louise Olson
Journal: Diabetes
Diabetes 2010;59(4):800–807
https://doi.org/10.2337/db09-1542
Published: 26 January 2010
View articletitled, Acute Inhibition of Fatty Acid Import Inhibits GLUT4 Transcription in Adipose Tissue, but Not Skeletal or Cardiac Muscle Tissue, Partly Through Liver X Receptor (LXR) Signaling
Open the PDF for Acute Inhibition of Fatty Acid Import Inhibits GLUT4 Transcription in Adipose Tissue, but Not Skeletal or Cardiac Muscle Tissue, Partly Through Liver X Receptor (LXR) Signaling in another window