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Journal Articles

Maintaining Myocardial Glucose Utilization in Diabetic Cardiomyopathy Accelerates Mitochondrial Dysfunction

Adam R. Wende, John C. Schell, Chae-Myeong Ha, Mark E. Pepin, Oleh Khalimonchuk, Hansjörg Schwertz, Renata O. Pereira, Manoja K. Brahma, Joseph Tuinei, Ariel Contreras-Ferrat, Li Wang, Chase A. Andrizzi, Curtis D. Olsen, Wayne E. Bradley, Louis J. Dell’Italia, Wolfgang H. Dillmann, Sheldon E. Litwin, E. Dale Abel

Diabetes 2020;69(10):2094–2111

DOI: https://doi.org/10.2337/db19-1057

Published: 04 May 2020

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Meeting Abstracts

1984-P: Optic Atrophy 1 Deletion in Brown Adipose Tissue Induces Browning of White Fat by Inducing FGF-21

RENATA PEREIRA ALAMBERT, SATYA MURTHY TADINADA, E. DALE ABEL

Diabetes 2019;68(Supplement_1):1984-P

DOI: https://doi.org/10.2337/db19-1984-P

Published: 01 June 2019

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Journal Articles

Glucose Metabolism Is Required for Platelet Hyperactivation in a Murine Model of Type 1 Diabetes

Trevor P. Fidler, Alex Marti, Katelyn Gerth, Elizabeth A. Middleton, Robert A. Campbell, Matthew T. Rondina, Andrew S. Weyrich, E. Dale Abel

Diabetes 2019;68(5):932–938

DOI: https://doi.org/10.2337/db18-0981

Published: 14 February 2019

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Includes: Supplementary data

Meeting Abstracts

Resistance to Diet-Induced Obesity in Mice Lacking OPA1 in Adipose Tissue Occurs Independently of Fat-Derived FGF-21 and BAT Function

RENATA PEREIRA, ANGELA C. OLVERA, ALEX A. MARTI, RANA HEWEZI, WILLIAM A. BUI TRAN, MATTHEW J. POTTHOFF, E. DALE ABEL

Diabetes 2018;67(Supplement_1):276-LB

DOI: https://doi.org/10.2337/db18-276-LB

Published: 01 July 2018

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Meeting Abstracts

Sex Differences in the Response of C57BL/6 Mice to Ketogenic Diets

JESSE COCHRAN, PAUL V. TAUFALELE, KEVIN D. LIN, YUAN ZHANG, E. DALE ABEL

Diabetes 2018;67(Supplement_1):1884-P

DOI: https://doi.org/10.2337/db18-1884-P

Published: 01 July 2018

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Meeting Abstracts

Regulation of Hepatic Insulin Sensitivity and Hepatic Steatosis by ULK1

YOUNGDO KOO, MICHAEL P. GARNEAU, QUANJIANG ZHANG, E. DALE ABEL

Diabetes 2018;67(Supplement_1):1863-P

DOI: https://doi.org/10.2337/db18-1863-P

Published: 01 July 2018

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Journal Articles

Mitochondrial Calpain-1 Disrupts ATP Synthase and Induces Superoxide Generation in Type 1 Diabetic Hearts: A Novel Mechanism Contributing to Diabetic Cardiomyopathy

Rui Ni, Dong Zheng, Sidong Xiong, David J. Hill, Tao Sun, Richard B. Gardiner, Guo-Chang Fan, Yanrong Lu, E. Dale Abel, Peter A. Greer, Tianqing Peng

Diabetes 2016;65(1):255–268

DOI: https://doi.org/10.2337/db15-0963

Published: 15 October 2015

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Includes: Supplementary data

Journal Articles

Ceramide-Initiated Protein Phosphatase 2A Activation Contributes to Arterial Dysfunction In Vivo

Diabetes 2015;64(11):3914–3926

DOI: https://doi.org/10.2337/db15-0244

Published: 07 August 2015

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Includes: Supplementary data

Journal Articles

Insulin Inhibits Cardiac Contractility by Inducing a G_i-Biased β₂-Adrenergic Signaling in Hearts

Qin Fu, Bing Xu, Yongming Liu, Dippal Parikh, Jing Li, Ying Li, Yuan Zhang, Christian Riehle, Yi Zhu, Tenley Rawlings, Qian Shi, Richard B. Clark, Xiongwen Chen, E. Dale Abel, Yang K. Xiang

Diabetes 2014;63(8):2676–2689

DOI: https://doi.org/10.2337/db13-1763

Published: 17 July 2014

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Includes: Supplementary data

Journal Articles

Time to Look Back and to Look Forward

K. Sreekumaran Nair, E. Dale Abel, Sharon G. Adler, Peter J. Dyck, Thomas W. Gardner, Kathryn M. Haskins, Gökhan Hotamisligil, Michael D. Jensen, Anna Krook, Lawrence J. Mandarino, Braxton D. Mitchell, Jeffrey E. Pessin, James R. Sowers, Lori Sussel, Nick Wareham, Adrian Vella

Diabetes 2014;63(4):1169–1170

DOI: https://doi.org/10.2337/db14-0067

Published: 13 March 2014

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Journal Articles

Podocyte-Specific GLUT4-Deficient Mice Have Fewer and Larger Podocytes and Are Protected From Diabetic Nephropathy

Diabetes 2014;63(2):701–714

DOI: https://doi.org/10.2337/db13-0752

Published: 16 January 2014

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Includes: Supplementary data

Journal Articles

UCP3 Regulates Cardiac Efficiency and Mitochondrial Coupling in High Fat–Fed Mice but Not in Leptin-Deficient Mice

Sihem Boudina, Yong Hwan Han, Shaobo Pei, Timothy J. Tidwell, Brandon Henrie, Joseph Tuinei, Curtis Olsen, Sandra Sena, E. Dale Abel

Diabetes 2012;61(12):3260–3269

DOI: https://doi.org/10.2337/db12-0063

Published: 15 November 2012

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Includes: Supplementary data

Journal Articles

Ceramide Mediates Vascular Dysfunction in Diet-Induced Obesity by PP2A-Mediated Dephosphorylation of the eNOS-Akt Complex

Diabetes 2012;61(7):1848–1859

DOI: https://doi.org/10.2337/db11-1399

Published: 15 June 2012

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Includes: Supplementary data

Journal Articles

Targeted Inhibition of Calpain Reduces Myocardial Hypertrophy and Fibrosis in Mouse Models of Type 1 Diabetes

Ying Li, Jian Ma, Huaqing Zhu, Manpreet Singh, David Hill, Peter A. Greer, J. Malcolm Arnold, E. Dale Abel, Tianqing Peng

Diabetes 2011;60(11):2985–2994

DOI: https://doi.org/10.2337/db10-1333

Published: 17 October 2011

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Includes: Supplementary data

Journal Articles

Oxidative Phosphorylation Flexibility in the Liver of Mice Resistant to High-Fat Diet–Induced Hepatic Steatosis

Carinne Poussin, Mark Ibberson, Diana Hall, Jun Ding, Jamie Soto, E. Dale Abel, Bernard Thorens

Diabetes 2011;60(9):2216–2224

DOI: https://doi.org/10.2337/db11-0338

Published: 20 August 2011

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Includes: Supplementary data

Journal Articles

Central Leptin Signaling Is Required to Normalize Myocardial Fatty Acid Oxidation Rates in Caloric-Restricted ob/ob Mice

Crystal Sloan, Joseph Tuinei, Katherine Nemetz, Jonathan Frandsen, Jamie Soto, Noah Wride, Tomoki Sempokuya, Luis Alegria, Heiko Bugger, E. Dale Abel

Diabetes 2011;60(5):1424–1434

DOI: https://doi.org/10.2337/db10-1106

Published: 23 April 2011

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Includes: Supplementary data

Journal Articles

Iron Overload and Diabetes Risk: A Shift From Glucose to Fatty Acid Oxidation and Increased Hepatic Glucose Production in a Mouse Model of Hereditary Hemochromatosis

Jingyu Huang, Deborah Jones, Bai Luo, Michael Sanderson, Jamie Soto, E. Dale Abel, Robert C. Cooksey, Donald A. McClain

Diabetes 2011;60(1):80–87

DOI: https://doi.org/10.2337/db10-0593

Published: 28 September 2010

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Journal Articles

Acute Inhibition of Fatty Acid Import Inhibits GLUT4 Transcription in Adipose Tissue, but Not Skeletal or Cardiac Muscle Tissue, Partly Through Liver X Receptor (LXR) Signaling

Beth A. Griesel, Juston Weems, Robert A. Russell, E. Dale Abel, Kenneth Humphries, Ann Louise Olson

Diabetes 2010;59(4):800–807

DOI: https://doi.org/10.2337/db09-1542

Published: 26 January 2010

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Journal Articles

Tissue-Specific Remodeling of the Mitochondrial Proteome in Type 1 Diabetic Akita Mice

Heiko Bugger, Dong Chen, Christian Riehle, Jamie Soto, Heather A. Theobald, Xiao X. Hu, Balasubramanian Ganesan, Bart C. Weimer, E. Dale Abel

Diabetes 2009;58(9):1986–1997

DOI: https://doi.org/10.2337/db09-0259

Published: 19 June 2009

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Includes: Supplementary data

Journal Articles

Type 1 Diabetic Akita Mouse Hearts Are Insulin Sensitive but Manifest Structurally Abnormal Mitochondria That Remain Coupled Despite Increased Uncoupling Protein 3

Heiko Bugger, Sihem Boudina, Xiao Xuan Hu, Joseph Tuinei, Vlad G. Zaha, Heather A. Theobald, Ui Jeong Yun, Alfred P. McQueen, Benjamin Wayment, Sheldon E. Litwin, E. Dale Abel

Diabetes 2008;57(11):2924–2932

DOI: https://doi.org/10.2337/db08-0079

Published: 01 November 2008

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Includes: Supplementary data

NARROW

Maintaining Myocardial Glucose Utilization in Diabetic Cardiomyopathy Accelerates Mitochondrial Dysfunction

1984-P: Optic Atrophy 1 Deletion in Brown Adipose Tissue Induces Browning of White Fat by Inducing FGF-21

Glucose Metabolism Is Required for Platelet Hyperactivation in a Murine Model of Type 1 Diabetes

Resistance to Diet-Induced Obesity in Mice Lacking OPA1 in Adipose Tissue Occurs Independently of Fat-Derived FGF-21 and BAT Function

Sex Differences in the Response of C57BL/6 Mice to Ketogenic Diets

Regulation of Hepatic Insulin Sensitivity and Hepatic Steatosis by ULK1

Mitochondrial Calpain-1 Disrupts ATP Synthase and Induces Superoxide Generation in Type 1 Diabetic Hearts: A Novel Mechanism Contributing to Diabetic Cardiomyopathy

Ceramide-Initiated Protein Phosphatase 2A Activation Contributes to Arterial Dysfunction In Vivo

Insulin Inhibits Cardiac Contractility by Inducing a G_i-Biased β₂-Adrenergic Signaling in Hearts

Time to Look Back and to Look Forward

Podocyte-Specific GLUT4-Deficient Mice Have Fewer and Larger Podocytes and Are Protected From Diabetic Nephropathy

UCP3 Regulates Cardiac Efficiency and Mitochondrial Coupling in High Fat–Fed Mice but Not in Leptin-Deficient Mice

Ceramide Mediates Vascular Dysfunction in Diet-Induced Obesity by PP2A-Mediated Dephosphorylation of the eNOS-Akt Complex

Targeted Inhibition of Calpain Reduces Myocardial Hypertrophy and Fibrosis in Mouse Models of Type 1 Diabetes

Oxidative Phosphorylation Flexibility in the Liver of Mice Resistant to High-Fat Diet–Induced Hepatic Steatosis

Central Leptin Signaling Is Required to Normalize Myocardial Fatty Acid Oxidation Rates in Caloric-Restricted ob/ob Mice

Iron Overload and Diabetes Risk: A Shift From Glucose to Fatty Acid Oxidation and Increased Hepatic Glucose Production in a Mouse Model of Hereditary Hemochromatosis

Acute Inhibition of Fatty Acid Import Inhibits GLUT4 Transcription in Adipose Tissue, but Not Skeletal or Cardiac Muscle Tissue, Partly Through Liver X Receptor (LXR) Signaling

Tissue-Specific Remodeling of the Mitochondrial Proteome in Type 1 Diabetic Akita Mice

Type 1 Diabetic Akita Mouse Hearts Are Insulin Sensitive but Manifest Structurally Abnormal Mitochondria That Remain Coupled Despite Increased Uncoupling Protein 3

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