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Meeting Abstracts

1973-LB: Glucagon-Like Peptide 1 Receptor Agonist with Basal Insulin vs. Basal-Bolus Regimen on Glycemic Variability and Time-in-Range in Type 2 Diabetes Patients with Chronic Kidney Disease—A Randomised Controlled Trial

Free
JAMES LING, JACK K. NG, AIMIN YANG, ANDREA LUK, ALICE P. KONG, RONALD C. MA, CHEUK CHUN SZETO, JULIANA C. CHAN, ELAINE CHOW
Journal: Diabetes
Diabetes 2024;74(Supplement_1):1973-LB
https://doi.org/10.2337/db25-1973-LB
Published: 20 June 2025
View articletitled, 1973-LB: Glucagon-Like Peptide 1 Receptor Agonist with Basal Insulin vs. Basal-Bolus Regimen on Glycemic Variability and Time-in-Range in Type 2 Diabetes Patients with Chronic Kidney Disease—A Randomised Controlled Trial
Meeting Abstracts

331-OR: Modelling the Legacy Effect of Glycaemic Exposure on Long-Term Cardiovascular Disease in Newly Diagnosed Type 2 Diabetes

Free
XINGE ZHANG, AIMIN YANG, HONGJIANG WU, ERIC S.H. LAU, MAI SHI, BAOQI FAN, JIAZHOU YU, YANTING HUANG, JULIANA N.M. LUI, ALICE P. KONG, JULIANA C. CHAN, ELAINE CHOW, RONALD C. MA, ANDREA LUK
Journal: Diabetes
Diabetes 2024;74(Supplement_1):331-OR
https://doi.org/10.2337/db25-331-OR
Published: 20 June 2025
View articletitled, 331-OR: Modelling the Legacy Effect of Glycaemic Exposure on Long-Term Cardiovascular Disease in Newly Diagnosed Type 2 Diabetes
Meeting Abstracts

1397-P: Real-World Evidence on the Legacy Effect of Early vs. Late Glycaemic Reduction and All-Cause Mortality in Newly Diagnosed Type 2 Diabetes

Free
AIMIN YANG, XINGE ZHANG, MAI SHI, HONGJIANG WU, ERIC S.H. LAU, JIAZHOU YU, BAOQI FAN, YANTING HUANG, JULIANA N.M. LUI, ALICE P. KONG, ANDREA LUK, RONALD C. MA, JULIANA C. CHAN, ELAINE CHOW
Journal: Diabetes
Diabetes 2024;74(Supplement_1):1397-P
https://doi.org/10.2337/db25-1397-P
Published: 20 June 2025
View articletitled, 1397-P: Real-World Evidence on the Legacy Effect of Early vs. Late Glycaemic Reduction and All-Cause Mortality in Newly Diagnosed Type 2 Diabetes
Meeting Abstracts

1304-P: Trends in Use of Medications for Multifactorial Cardiovascular Risk Factor Intervention in Adults with Diabetes in Hong Kong, 2002–2019

Free
JIAZHOU YU, AIMIN YANG, HONGJIANG WU, ERIC S.H. LAU, MAI SHI, YINCONG XUE, XINGE ZHANG, BAOQI FAN, JULIANA N.M. LUI, ALICE P. KONG, RONALD C. MA, ANDREA LUK, JULIANA C. CHAN, ELAINE CHOW
Journal: Diabetes
Diabetes 2024;74(Supplement_1):1304-P
https://doi.org/10.2337/db25-1304-P
Published: 20 June 2025
View articletitled, 1304-P: Trends in Use of Medications for Multifactorial Cardiovascular Risk Factor Intervention in Adults with Diabetes in Hong Kong, 2002–2019
Meeting Abstracts

718-P: A High FODMAP Diet Reduces Glycemic Excursion without Increasing Gastrointestinal Symptoms in Individuals with Prediabetes Treated with Metformin—A Randomized Crossover Controlled-Feeding Trial

Free
NATURAL CHU, EMILY W.M. POON, JULIANA C. CHAN, ELAINE CHOW
Journal: Diabetes
Diabetes 2024;73(Supplement_1):718-P
https://doi.org/10.2337/db24-718-P
Published: 14 June 2024
View articletitled, 718-P: A High FODMAP Diet Reduces Glycemic Excursion without Increasing Gastrointestinal Symptoms in Individuals with Prediabetes Treated with Metformin—A Randomized Crossover Controlled-Feeding Trial
Meeting Abstracts

418-P: Rosuvastatin vs. Atorvastatin on Cardiorenal Outcomes in Chinese People with Diabetes With and Without Chronic Kidney Disease

Free
YANTING HUANG, AIMIN YANG, MAI SHI, HONGJIANG WU, TINGTING CHEN, CALVIN KE, JULIANA N.M. LUI, ALICE P. KONG, RONALD C. MA, ANDREA LUK, JULIANA C. CHAN, ELAINE CHOW
Journal: Diabetes
Diabetes 2024;73(Supplement_1):418-P
https://doi.org/10.2337/db24-418-P
Published: 14 June 2024
View articletitled, 418-P: Rosuvastatin vs. Atorvastatin on Cardiorenal Outcomes in Chinese People with Diabetes With and Without Chronic Kidney Disease
Meeting Abstracts

1887-LB: Effect of Dorzagliatin, a Dual-Acting Glucokinase Activator, on Insulin and Glucagon Secretion in Impaired and Normal Glucose Tolerance

Free
ZHENGLI BAI, KE WANG, TIFFANY TSE LING YAU, EMILY W. POON, ANDREA LUK, RONALD C. MA, ALICE P. KONG, ELAINE CHOW, LI CHEN, JULIANA C. CHAN
Journal: Diabetes
Diabetes 2024;73(Supplement_1):1887-LB
https://doi.org/10.2337/db24-1887-LB
Published: 14 June 2024
View articletitled, 1887-LB: Effect of Dorzagliatin, a Dual-Acting Glucokinase Activator, on Insulin and Glucagon Secretion in Impaired and Normal Glucose Tolerance
Meeting Abstracts

1477-P: Polygenic Risk Score (PRS) Derived from Common Variants of Monogenic Diabetes Genes (MDG) Predicts Young Onset Diabetes (YOD) and Cardiovascular(CV)-Kidney Complications

Free
CHUN KWAN O, BAOQI FAN, SANDRA T.F. TSOI, CLAUDIA H. TAM, RAYMOND WAN, ERIC S.H. LAU, MAI SHI, CADMON K.P. LIM, ELAINE CHOW, ALICE P. KONG, RONALD C. MA, ANDREA LUK, JULIANA C. CHAN
Journal: Diabetes
Diabetes 2024;73(Supplement_1):1477-P
https://doi.org/10.2337/db24-1477-P
Published: 14 June 2024
View articletitled, 1477-P: Polygenic Risk Score (PRS) Derived from Common Variants of Monogenic Diabetes Genes (MDG) Predicts Young Onset Diabetes (YOD) and Cardiovascular(CV)-Kidney Complications
Journal Articles

Comparison of β-Cell Function and Insulin Sensitivity Between Normal-Weight and Obese Chinese With Young-Onset Type 2 Diabetes

Free
Yingnan Fan, Elaine Chow, Cadmon K.P. Lim, Yong Hou, Sandra T.F. Tsoi, Baoqi Fan, Eric S.H. Lau, Alice P.S. Kong, Ronald C.W. Ma, Hongjiang Wu, Juliana C.N. Chan, Andrea O.Y. Luk
Journal: Diabetes
Diabetes 2024;73(6):953–963
https://doi.org/10.2337/db23-0966
Published: 20 March 2024
View articletitled, Comparison of β-Cell Function and Insulin Sensitivity Between Normal-Weight and Obese Chinese With Young-Onset Type 2 Diabetes
Open the PDF for Comparison of β-Cell Function and Insulin Sensitivity Between Normal-Weight and Obese Chinese With Young-Onset Type 2 Diabetes in another window
Meeting Abstracts

1829-PUB: Precision Medicine to Redefine Insulin Secretion and Monogenic Diabetes Randomised Controlled Trial (PRISM-RCT) in Chinese Patients with Young-Onset Diabetes—Study Design and Baseline Profile

Free
ANDREA LUK, YINGNAN FAN, BAOQI FAN, CADMON K.P. LIM, ERIC S.H. LAU, EMILY W.M. POON, SANDRA T.F. TSOI, RISA OZAKI, RONALD C. MA, ELAINE CHOW, ALICE P. KONG, JULIANA C. CHAN
Journal: Diabetes
Diabetes 2023;72(Supplement_1):1829-PUB
https://doi.org/10.2337/db23-1829-PUB
Published: 23 June 2023
View articletitled, 1829-PUB: Precision Medicine to Redefine Insulin Secretion and Monogenic Diabetes Randomised Controlled Trial (PRISM-RCT) in Chinese Patients with Young-Onset Diabetes—Study Design and Baseline Profile
Meeting Abstracts

978-P: Correlation between Continuous Glucose Monitoring Metrics, Oral Glucose Tolerance Test, and HbA1c in Individuals with Impaired Glucose Tolerance

Free
ELAINE CHOW, JIE HE, NATURAL CHU, EMILY W.M. POON, JULIANA C. CHAN
Journal: Diabetes
Diabetes 2023;72(Supplement_1):978-P
https://doi.org/10.2337/db23-978-P
Published: 20 June 2023
View articletitled, 978-P: Correlation between Continuous Glucose Monitoring Metrics, Oral Glucose Tolerance Test, and HbA1c in Individuals with Impaired Glucose Tolerance
Meeting Abstracts

1317-P: The Use of NT-proBNP for Risk Stratification of Incident Cardiorenal Complications in Type 2 Diabetes—The Hong Kong Diabetes Biobank

Free
RONALD C.W. MA, CLAUDIA H. TAM, YONG HOU, QIAO JIN, ERIC S.H. LAU, RISA OZAKI, ALICE P. KONG, ELAINE CHOW, ANDREA LUK, CADMON K.P. LIM, JULIANA C. CHAN, THE HONG KONG DIABETES BIOBANK STUDY GROUP
Journal: Diabetes
Diabetes 2023;72(Supplement_1):1317-P
https://doi.org/10.2337/db23-1317-P
Published: 20 June 2023
View articletitled, 1317-P: The Use of NT-proBNP for Risk Stratification of Incident Cardiorenal Complications in Type 2 Diabetes—The Hong Kong Diabetes Biobank
Meeting Abstracts

1406-P: Trends in All-Cause and Cause-Specific Mortality in Older Adults With and Without Diabetes—A Territory-Wide Analysis in One Million Older Adults in Hong Kong

Free
AIMIN YANG, MAI SHI, ERIC S.H. LAU, ELAINE CHOW, JULIANA C. CHAN
Journal: Diabetes
Diabetes 2023;72(Supplement_1):1406-P
https://doi.org/10.2337/db23-1406-P
Published: 20 June 2023
View articletitled, 1406-P: Trends in All-Cause and Cause-Specific Mortality in Older Adults With and Without Diabetes—A Territory-Wide Analysis in One Million Older Adults in Hong Kong
Meeting Abstracts

686-P: Risk Associations between Patient Reported Depression, Cardiovascular-Renal Events, All-Cause Mortality, and Potential Single-Item Patient Health Questionnaire (PHQ) Screening for All-Cause Mortality in Asians—Six-Year Prospective Analysis of the Hong Kong Diabetes Register

Free
JULIANA N.M. LUI, ERIC S.H. LAU, YIU LAM YEUNG, KA LONG LEE, TSUN FUNG YUNG, ALICE P. KONG, ANDREA LUK, ELAINE CHOW, RONALD C. MA, HOI MING THERESA YEUNG, KIT MAN LOO, RISA OZAKI, JULIANA C. CHAN
Journal: Diabetes
Diabetes 2023;72(Supplement_1):686-P
https://doi.org/10.2337/db23-686-P
Published: 20 June 2023
View articletitled, 686-P: Risk Associations between Patient Reported Depression, Cardiovascular-Renal Events, All-Cause Mortality, and Potential Single-Item Patient Health Questionnaire (PHQ) Screening for All-Cause Mortality in Asians—Six-Year Prospective Analysis of the Hong Kong Diabetes Register
Meeting Abstracts

1473-P: A Data-Driven Cluster Analysis of Renal Complications in Patients with Type 2 Diabetes—From Phenotypic Observation to Genetic Discovery

Free
MAI SHI, CLAUDIA H. TAM, ERIC S.H. LAU, AIMIN YANG, HONGJIANG WU, BAOQI FAN, ALICE P. KONG, ANDREA LUK, ELAINE CHOW, JULIANA C. CHAN, RONALD C. MA
Journal: Diabetes
Diabetes 2023;72(Supplement_1):1473-P
https://doi.org/10.2337/db23-1473-P
Published: 20 June 2023
View articletitled, 1473-P: A Data-Driven Cluster Analysis of Renal Complications in Patients with Type 2 Diabetes—From Phenotypic Observation to Genetic Discovery
Meeting Abstracts

1251-P: Glycaemic Trajectory before Diabetes Diagnosis in People with Young-Onset and Usual-Onset Type 2 Diabetes—A Population-Based Retrospective Study in Hong Kong

Free
YINGNAN FAN, HONGJIANG WU, ERIC S.H. LAU, AIMIN YANG, ELAINE CHOW, ALICE P. KONG, RONALD C. MA, JULIANA C. CHAN, ANDREA LUK
Journal: Diabetes
Diabetes 2023;72(Supplement_1):1251-P
https://doi.org/10.2337/db23-1251-P
Published: 20 June 2023
View articletitled, 1251-P: Glycaemic Trajectory before Diabetes Diagnosis in People with Young-Onset and Usual-Onset Type 2 Diabetes—A Population-Based Retrospective Study in Hong Kong
Meeting Abstracts

126-OR: Metformin Discontinuation and Clinical Outcomes in Patients with Diabetes and Advanced Chronic Kidney Disease—A Prospective Cohort Study

Free
AIMIN YANG, MAI SHI, HONGJIANG WU, ERIC S.H. LAU, JOHNNY T.K. CHEUNG, XINGE ZHANG, BAOQI FAN, ALICE P. KONG, ANDREA LUK, RONALD C. MA, JULIANA C. CHAN, ELAINE CHOW
Journal: Diabetes
Diabetes 2023;72(Supplement_1):126-OR
https://doi.org/10.2337/db23-126-OR
Published: 20 June 2023
View articletitled, 126-OR: Metformin Discontinuation and Clinical Outcomes in Patients with Diabetes and Advanced Chronic Kidney Disease—A Prospective Cohort Study
Meeting Abstracts

1414-P: Stalling of Trends in Glycemic and Risk Factors Control in People with Type 2 Diabetes in Hong Kong in 2000–2019

Free
HONGJIANG WU, ERIC S.H. LAU, AIMIN YANG, XINGE ZHANG, BAOQI FAN, RONALD C. MA, ALICE P. KONG, ELAINE CHOW, JULIANA C. CHAN, ANDREA LUK
Journal: Diabetes
Diabetes 2023;72(Supplement_1):1414-P
https://doi.org/10.2337/db23-1414-P
Published: 20 June 2023
View articletitled, 1414-P: Stalling of Trends in Glycemic and Risk Factors Control in People with Type 2 Diabetes in Hong Kong in 2000–2019
Journal Articles

Dorzagliatin, a Dual-Acting Glucokinase Activator, Increases Insulin Secretion and Glucose Sensitivity in Glucokinase Maturity-Onset Diabetes of the Young and Recent-Onset Type 2 Diabetes

Free
Elaine Chow, Ke Wang, Cadmon K.P. Lim, Sandra T.F. Tsoi, Baoqi Fan, Emily Poon, Andrea O.Y. Luk, Ronald C.W. Ma, Ele Ferrannini, Andrea Mari, Li Chen, Juliana C.N. Chan
Journal: Diabetes
Diabetes 2023;72(2):299–308
https://doi.org/10.2337/db22-0708
Published: 28 October 2022
View articletitled, Dorzagliatin, a Dual-Acting Glucokinase Activator, Increases Insulin Secretion and Glucose Sensitivity in Glucokinase Maturity-Onset Diabetes of the Young and Recent-Onset Type 2 Diabetes
Open the PDF for Dorzagliatin, a Dual-Acting Glucokinase Activator, Increases Insulin Secretion and Glucose Sensitivity in Glucokinase Maturity-Onset Diabetes of the Young and Recent-Onset Type 2 Diabetes in another window
Meeting Abstracts

556-P: The Relationship between Short-Chain Fermentable Carbohydrates (FODMAPs) , Gut Microbiome, and Glucose Intolerance: An Exploratory Analysis

Free
NATURAL CHU, JIE HE, RONALD C. MA, ALICE P. KONG, JULIANA C. CHAN, ELAINE CHOW
Journal: Diabetes
Diabetes 2022;71(Supplement_1):556-P
https://doi.org/10.2337/db22-556-P
Published: 01 June 2022
View articletitled, 556-P: The Relationship between Short-Chain Fermentable Carbohydrates (FODMAPs) , Gut Microbiome, and Glucose Intolerance: An Exploratory Analysis