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Eleanor Wheeler
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Journal Articles

Genetically Predicted Glucose-Dependent Insulinotropic Polypeptide (GIP) Levels and Cardiovascular Disease Risk Are Driven by Distinct Causal Variants in the GIPR Region

Free
Nicholas Bowker, Robert Hansford, Stephen Burgess, Christopher N. Foley, Victoria P.W. Auyeung, A. Mesut Erzurumluoglu, Isobel D. Stewart, Eleanor Wheeler, Maik Pietzner, Fiona Gribble, Frank Reimann, Pallav Bhatnagar, Matthew P. Coghlan, Nicholas J. Wareham, Claudia Langenberg
Journal: Diabetes
Diabetes 2021;70(11):2706–2719
https://doi.org/10.2337/db21-0103
Published: 23 August 2021
View articletitled, Genetically Predicted Glucose-Dependent Insulinotropic Polypeptide (GIP) Levels and Cardiovascular Disease Risk Are Driven by Distinct Causal Variants in the GIPR Region
Open the PDF for Genetically Predicted Glucose-Dependent Insulinotropic Polypeptide (GIP) Levels and Cardiovascular Disease Risk Are Driven by Distinct Causal Variants in the GIPR Region in another window
Journal Articles

Genome-Wide Association Identifies Nine Common Variants Associated With Fasting Proinsulin Levels and Provides New Insights Into the Pathophysiology of Type 2 Diabetes

Open Access
Rona J. Strawbridge, Josée Dupuis, Inga Prokopenko, Adam Barker, Emma Ahlqvist, Denis Rybin, John R. Petrie, Mary E. Travers, Nabila Bouatia-Naji, Antigone S. Dimas, Alexandra Nica, Eleanor Wheeler, Han Chen, Benjamin F. Voight, Jalal Taneera, Stavroula Kanoni, John F. Peden, Fabiola Turrini, Stefan Gustafsson, Carina Zabena, Peter Almgren, David J.P. Barker, Daniel Barnes, Elaine M. Dennison, Johan G. Eriksson, Per Eriksson, Elodie Eury, Lasse Folkersen, Caroline S. Fox, Timothy M. Frayling, Anuj Goel, Harvest F. Gu, Momoko Horikoshi, Bo Isomaa, Anne U. Jackson, Karen A. Jameson, Eero Kajantie, Julie Kerr-Conte, Teemu Kuulasmaa, Johanna Kuusisto, Ruth J.F. Loos, Jian'an Luan, Konstantinos Makrilakis, Alisa K. Manning, María Teresa Martínez-Larrad, Narisu Narisu, Maria Nastase Mannila, John Öhrvik, Clive Osmond, Laura Pascoe, Felicity Payne, Avan A. Sayer, Bengt Sennblad, Angela Silveira, Alena Stančáková, Kathy Stirrups, Amy J. Swift, Ann-Christine Syvänen, Tiinamaija Tuomi, Ferdinand M. van 't Hooft, Mark Walker, Michael N. Weedon, Weijia Xie, Björn Zethelius, the DIAGRAM Consortium, the GIANT Consortium, the MuTHER Consortium, the CARDIoGRAM Consortium, the C4D Consortium, Halit Ongen, Anders Mälarstig, Jemma C. Hopewell, Danish Saleheen, John Chambers, Sarah Parish, John Danesh, Jaspal Kooner, Claes-Göran Östenson, Lars Lind, Cyrus C. Cooper, Manuel Serrano-Ríos, Ele Ferrannini, Tom J. Forsen, Robert Clarke, Maria Grazia Franzosi, Udo Seedorf, Hugh Watkins, Philippe Froguel, Paul Johnson, Panos Deloukas, Francis S. Collins, Markku Laakso, Emmanouil T. Dermitzakis, Michael Boehnke, Mark I. McCarthy, Nicholas J. Wareham, Leif Groop, François Pattou, Anna L. Gloyn, George V. Dedoussis, Valeriya Lyssenko, James B. Meigs, Inês Barroso, Richard M. Watanabe, Erik Ingelsson, Claudia Langenberg, Anders Hamsten, Jose C. Florez
Journal: Diabetes
Diabetes 2011;60(10):2624–2634
https://doi.org/10.2337/db11-0415
Published: 16 September 2011
View articletitled, Genome-Wide Association Identifies Nine Common Variants Associated With Fasting Proinsulin Levels and Provides New Insights Into the Pathophysiology of Type 2 Diabetes
Open the PDF for Genome-Wide Association Identifies Nine Common Variants Associated With Fasting Proinsulin Levels and Provides New Insights Into the Pathophysiology of Type 2 Diabetes in another window
Includes: Supplementary data
Journal Articles

Common Variants at 10 Genomic Loci Influence Hemoglobin A1C Levels via Glycemic and Nonglycemic Pathways

Open Access
Nicole Soranzo, Serena Sanna, Eleanor Wheeler, Christian Gieger, Dörte Radke, Josée Dupuis, Nabila Bouatia-Naji, Claudia Langenberg, Inga Prokopenko, Elliot Stolerman, Manjinder S. Sandhu, Matthew M. Heeney, Joseph M. Devaney, Muredach P. Reilly, Sally L. Ricketts
Journal: Diabetes
Diabetes 2010;59(12):3229–3239
https://doi.org/10.2337/db10-0502
Published: 21 September 2010
View articletitled, Common Variants at 10 Genomic Loci Influence Hemoglobin A1C Levels via Glycemic and Nonglycemic Pathways
Open the PDF for Common Variants at 10 Genomic Loci Influence Hemoglobin A1C Levels via Glycemic and Nonglycemic Pathways in another window
Includes: Supplementary data
Journal Articles

Detailed Investigation of the Role of Common and Low-Frequency WFS1 Variants in Type 2 Diabetes Risk

Open Access
Katherine A. Fawcett, Eleanor Wheeler, Andrew P. Morris, Sally L. Ricketts, Göran Hallmans, Olov Rolandsson, Allan Daly, Jon Wasson, Alan Permutt, Andrew T. Hattersley, Benjamin Glaser, Paul W. Franks, Mark I. McCarthy, Nicholas J. Wareham, Manjinder S. Sandhu, Inês Barroso
Journal: Diabetes
Diabetes 2010;59(3):741–746
https://doi.org/10.2337/db09-0920
Published: 12 December 2009
View articletitled, Detailed Investigation of the Role of Common and Low-Frequency WFS1 Variants in Type 2 Diabetes Risk
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Includes: Supplementary data
Journal Articles

Population-Specific Risk of Type 2 Diabetes Conferred by HNF4A P2 Promoter Variants: A Lesson for Replication Studies

Free
Inês Barroso, Jian’an Luan, Eleanor Wheeler, Pamela Whittaker, Jon Wasson, Eleftheria Zeggini, Michael N. Weedon, Sarah Hunt, Ranganath Venkatesh, Timothy M. Frayling, Marcos Delgado, Rosalind J. Neuman, Jinghua Zhao, Richard Sherva, Benjamin Glaser, Mark Walker, Graham Hitman, Mark I. McCarthy, Andrew T. Hattersley, M. Alan Permutt, Nicholas J. Wareham, Panagiotis Deloukas
Journal: Diabetes
Diabetes 2008;57(11):3161–3165
https://doi.org/10.2337/db08-0719
Published: 01 November 2008
View articletitled, Population-Specific Risk of Type 2 Diabetes Conferred by HNF4A P2 Promoter Variants: A Lesson for Replication Studies
Open the PDF for Population-Specific Risk of Type 2 Diabetes Conferred by HNF4A P2 Promoter Variants: A Lesson for Replication Studies in another window
Includes: Supplementary data
Journal Articles

Evaluating the Role of LPIN1 Variation in Insulin Resistance, Body Weight, and Human Lipodystrophy in U.K. Populations

Free
Katherine A. Fawcett, Neil Grimsey, Ruth J.F. Loos, Eleanor Wheeler, Allan Daly, Maria Soos, Robert Semple, Holly Syddall, Cyrus Cooper, Symeon Siniossoglou, Stephen O'Rahilly, Nicholas J. Wareham, Inês Barroso
Journal: Diabetes
Diabetes 2008;57(9):2527–2533
https://doi.org/10.2337/db08-0422
Published: 01 September 2008
View articletitled, Evaluating the Role of LPIN1 Variation in Insulin Resistance, Body Weight, and Human Lipodystrophy in U.K. Populations
Open the PDF for Evaluating the Role of LPIN1 Variation in Insulin Resistance, Body Weight, and Human Lipodystrophy in U.K. Populations in another window
Includes: Supplementary data