1-9 of 9
Esteban N. Gurzov
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

PTPN2 Regulates the Interferon Signaling and Endoplasmic Reticulum Stress Response in Pancreatic β-Cells in Autoimmune Diabetes

Bernat Elvira, Valerie Vandenbempt, Julia Bauzá-Martinez, Raphaël Crutzen, Javier Negueruela, Hazem Ibrahim, Matthew L. Winder, Manoja K. Brahma, Beata Vekeriotaite, Pieter-Jan Martens, Sumeet Pal Singh, Fernando Rossello, Pascale Lybaert, Timo Otonkoski, Conny Gysemans, Wei Wu, Esteban N. Gurzov
Journal: Diabetes
Diabetes 2022;71(4):653–668
https://doi.org/10.2337/db21-0443
Published: 19 January 2022
View article titled, PTPN2 Regulates the Interferon Signaling and Endoplasmic Reticulum Stress Response in Pancreatic β-Cells in Autoimmune Diabetes
Open the PDF for PTPN2 Regulates the Interferon Signaling and Endoplasmic Reticulum Stress Response in Pancreatic β-Cells in Autoimmune Diabetes in another window
Journal Articles

STAT3 Regulates Mitochondrial Gene Expression in Pancreatic β-Cells and Its Deficiency Induces Glucose Intolerance in Obesity

Anaïs Schaschkow, Lokman Pang, Valerie Vandenbempt, Bernat Elvira, Sara A. Litwak, Beata Vekeriotaite, Elisa Maillard, Marjorie Vermeersch, Flavia M.M. Paula, Michel Pinget, David Perez-Morga, Daniel J. Gough, Esteban N. Gurzov
Journal: Diabetes
Diabetes 2021;70(9):2026–2041
https://doi.org/10.2337/db20-1222
Published: 28 June 2021
View article titled, STAT3 Regulates Mitochondrial Gene Expression in Pancreatic β-Cells and Its Deficiency Induces Glucose Intolerance in Obesity
Open the PDF for STAT3 Regulates Mitochondrial Gene Expression in Pancreatic β-Cells and Its Deficiency Induces Glucose Intolerance in Obesity in another window
Journal Articles

JNK Activation of BIM Promotes Hepatic Oxidative Stress, Steatosis, and Insulin Resistance in Obesity

Sara A. Litwak, Lokman Pang, Sandra Galic, Mariana Igoillo-Esteve, William J. Stanley, Jean-Valery Turatsinze, Kim Loh, Helen E. Thomas, Arpeeta Sharma, Eric Trepo, Christophe Moreno, Daniel J. Gough, Decio L. Eizirik, Judy B. de Haan, Esteban N. Gurzov
Journal: Diabetes
Diabetes 2017;66(12):2973–2986
https://doi.org/10.2337/db17-0348
Published: 19 September 2017
View article titled, JNK Activation of BIM Promotes Hepatic Oxidative Stress, Steatosis, and Insulin Resistance in Obesity
Open the PDF for JNK Activation of BIM Promotes Hepatic Oxidative Stress, Steatosis, and Insulin Resistance in Obesity in another window
Includes: Supplementary data
Journal Articles

BIM Deficiency Protects NOD Mice From Diabetes by Diverting Thymocytes to Regulatory T Cells

Balasubramanian Krishnamurthy, Jonathan Chee, Gaurang Jhala, Prerak Trivedi, Tara Catterall, Claudia Selck, Esteban N. Gurzov, Thomas C. Brodnicki, Kate L. Graham, Jibran A. Wali, Yifan Zhan, Daniel Gray, Andreas Strasser, Janette Allison, Helen E. Thomas, Thomas W.H. Kay
Journal: Diabetes
Diabetes 2015;64(9):3229–3238
https://doi.org/10.2337/db14-1851
Published: 06 May 2015
View article titled, BIM Deficiency Protects NOD Mice From Diabetes by Diverting Thymocytes to Regulatory T Cells
Open the PDF for BIM Deficiency Protects NOD Mice From Diabetes by Diverting Thymocytes to Regulatory T Cells in another window
Includes: Supplementary data
Journal Articles

Inactivation of Protein Tyrosine Phosphatases Enhances Interferon Signaling in Pancreatic Islets

William J. Stanley, Sara A. Litwak, Hong Sheng Quah, Sih Min Tan, Thomas W.H. Kay, Tony Tiganis, Judy B. de Haan, Helen E. Thomas, Esteban N. Gurzov
Journal: Diabetes
Diabetes 2015;64(7):2489–2496
https://doi.org/10.2337/db14-1575
Published: 02 March 2015
View article titled, Inactivation of Protein Tyrosine Phosphatases Enhances Interferon Signaling in Pancreatic Islets
Open the PDF for Inactivation of Protein Tyrosine Phosphatases Enhances Interferon Signaling in Pancreatic Islets in another window
Includes: Supplementary data
Journal Articles

Death Protein 5 and p53-Upregulated Modulator of Apoptosis Mediate the Endoplasmic Reticulum Stress–Mitochondrial Dialog Triggering Lipotoxic Rodent and Human β-Cell Apoptosis

Daniel A. Cunha, Mariana Igoillo-Esteve, Esteban N. Gurzov, Carla M. Germano, Najib Naamane, Ihsane Marhfour, Makiko Fukaya, Jean-Marie Vanderwinden, Conny Gysemans, Chantal Mathieu, Lorella Marselli, Piero Marchetti, Heather P. Harding, David Ron, Décio L. Eizirik, Miriam Cnop
Journal: Diabetes
Diabetes 2012;61(11):2763–2775
https://doi.org/10.2337/db12-0123
Published: 16 October 2012
View article titled, Death Protein 5 and p53-Upregulated Modulator of Apoptosis Mediate the Endoplasmic Reticulum Stress–Mitochondrial Dialog Triggering Lipotoxic Rodent and Human β-Cell Apoptosis
Open the PDF for Death Protein 5 and p53-Upregulated Modulator of Apoptosis Mediate the Endoplasmic Reticulum Stress–Mitochondrial Dialog Triggering Lipotoxic Rodent and Human β-Cell Apoptosis in another window
Includes: Supplementary data
Journal Articles

PTPN2, a Candidate Gene for Type 1 Diabetes, Modulates Pancreatic β-Cell Apoptosis via Regulation of the BH3-Only Protein Bim

Izortze Santin, Fabrice Moore, Maikel L. Colli, Esteban N. Gurzov, Lorella Marselli, Piero Marchetti, Decio L. Eizirik
Journal: Diabetes
Diabetes 2011;60(12):3279–3288
https://doi.org/10.2337/db11-0758
Published: 13 November 2011
View article titled, <em>PTPN2</em>, a Candidate Gene for Type 1 Diabetes, Modulates Pancreatic β-Cell Apoptosis via Regulation of the BH3-Only Protein Bim
Open the PDF for <em>PTPN2</em>, a Candidate Gene for Type 1 Diabetes, Modulates Pancreatic β-Cell Apoptosis via Regulation of the BH3-Only Protein Bim in another window
Includes: Supplementary data
Journal Articles

Peripheral and Islet Interleukin-17 Pathway Activation Characterizes Human Autoimmune Diabetes and Promotes Cytokine-Mediated β-Cell Death

Sefina Arif, Fabrice Moore, Katherine Marks, Thomas Bouckenooghe, Colin M. Dayan, Raquel Planas, Marta Vives-Pi, Jake Powrie, Timothy Tree, Piero Marchetti, Guo Cai Huang, Esteban N. Gurzov, Ricardo Pujol-Borrell, Decio L. Eizirik, Mark Peakman
Journal: Diabetes
Diabetes 2011;60(8):2112–2119
https://doi.org/10.2337/db10-1643
Published: 18 July 2011
View article titled, Peripheral and Islet Interleukin-17 Pathway Activation Characterizes Human Autoimmune Diabetes and Promotes Cytokine-Mediated β-Cell Death
Open the PDF for Peripheral and Islet Interleukin-17 Pathway Activation Characterizes Human Autoimmune Diabetes and Promotes Cytokine-Mediated β-Cell Death in another window
Includes: Supplementary data
Journal Articles

Glucagon-Like Peptide-1 Agonists Protect Pancreatic β-Cells From Lipotoxic Endoplasmic Reticulum Stress Through Upregulation of BiP and JunB

Daniel A. Cunha, Laurence Ladrière, Fernanda Ortis, Mariana Igoillo-Esteve, Esteban N. Gurzov, Roberto Lupi, Piero Marchetti, Décio L. Eizirik, Miriam Cnop
Journal: Diabetes
Diabetes 2009;58(12):2851–2862
https://doi.org/10.2337/db09-0685
Published: 31 August 2009
View article titled, Glucagon-Like Peptide-1 Agonists Protect Pancreatic β-Cells From Lipotoxic Endoplasmic Reticulum Stress Through Upregulation of BiP and JunB
Open the PDF for Glucagon-Like Peptide-1 Agonists Protect Pancreatic β-Cells From Lipotoxic Endoplasmic Reticulum Stress Through Upregulation of BiP and JunB in another window
Includes: Supplementary data