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Etienne Lefai
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Journal Articles

Disruption of Mitochondria-Associated Endoplasmic Reticulum Membrane (MAM) Integrity Contributes to Muscle Insulin Resistance in Mice and Humans

Emily Tubbs, Stéphanie Chanon, Maud Robert, Nadia Bendridi, Gabriel Bidaux, Marie-Agnès Chauvin, Jingwei Ji-Cao, Christine Durand, Daphné Gauvrit-Ramette, Hubert Vidal, Etienne Lefai, Jennifer Rieusset
Journal: Diabetes
Diabetes 2018;67(4):636–650
https://doi.org/10.2337/db17-0316
Published: 11 January 2018
View articletitled, Disruption of Mitochondria-Associated Endoplasmic Reticulum Membrane (MAM) Integrity Contributes to Muscle Insulin Resistance in Mice and Humans
Open the PDF for Disruption of Mitochondria-Associated Endoplasmic Reticulum Membrane (MAM) Integrity Contributes to Muscle Insulin Resistance in Mice and Humans in another window
Includes: Supplementary data
Journal Articles

Adipose Tissue–Derived Stem Cells From Obese Subjects Contribute to Inflammation and Reduced Insulin Response in Adipocytes Through Differential Regulation of the Th1/Th17 Balance and Monocyte Activation

Assia Eljaafari, Maud Robert, Marwa Chehimi, Stephanie Chanon, Christine Durand, Guillaume Vial, Nadia Bendridi, Anne-Marie Madec, Emmanuel Disse, Martine Laville, Jennifer Rieusset, Etienne Lefai, Hubert Vidal, Luciano Pirola
Journal: Diabetes
Diabetes 2015;64(7):2477–2488
https://doi.org/10.2337/db15-0162
Published: 12 March 2015
View articletitled, Adipose Tissue–Derived Stem Cells From Obese Subjects Contribute to Inflammation and Reduced Insulin Response in Adipocytes Through Differential Regulation of the Th1/Th17 Balance and Monocyte Activation
Open the PDF for Adipose Tissue–Derived Stem Cells From Obese Subjects Contribute to Inflammation and Reduced Insulin Response in Adipocytes Through Differential Regulation of the Th1/Th17 Balance and Monocyte Activation in another window
Includes: Supplementary data
Journal Articles

Adaptive Changes of the Insig1/SREBP1/SCD1 Set Point Help Adipose Tissue to Cope With Increased Storage Demands of Obesity

Stefania Carobbio, Rachel M. Hagen, Christopher J. Lelliott, Marc Slawik, Gema Medina-Gomez, Chong-Yew Tan, Audrey Sicard, Helen J. Atherton, Nuria Barbarroja, Mikael Bjursell, Mohammad Bohlooly-Y, Sam Virtue, Antoinette Tuthill, Etienne Lefai, Martine Laville, Tingting Wu, Robert V. Considine, Hubert Vidal, Dominique Langin, Matej Oresic, Francisco J. Tinahones, Jose Manuel Fernandez-Real, Julian L. Griffin, Jaswinder K. Sethi, Miguel López, Antonio Vidal-Puig
Journal: Diabetes
Diabetes 2013;62(11):3697–3708
https://doi.org/10.2337/db12-1748
Published: 18 October 2013
View articletitled, Adaptive Changes of the Insig1/SREBP1/SCD1 Set Point Help Adipose Tissue to Cope With Increased Storage Demands of Obesity
Open the PDF for Adaptive Changes of the Insig1/SREBP1/SCD1 Set Point Help Adipose Tissue to Cope With Increased Storage Demands of Obesity in another window
Includes: Supplementary data
Journal Articles

FTO Is Increased in Muscle During Type 2 Diabetes, and Its Overexpression in Myotubes Alters Insulin Signaling, Enhances Lipogenesis and ROS Production, and Induces Mitochondrial Dysfunction

Amélie Bravard, Etienne Lefai, Emmanuelle Meugnier, Sandra Pesenti, Emmanuel Disse, Julien Vouillarmet, Nöel Peretti, Rémi Rabasa-Lhoret, Martine Laville, Hubert Vidal, Jennifer Rieusset
Journal: Diabetes
Diabetes 2011;60(1):258–268
https://doi.org/10.2337/db10-0281
Published: 13 October 2010
View articletitled, FTO Is Increased in Muscle During Type 2 Diabetes, and Its Overexpression in Myotubes Alters Insulin Signaling, Enhances Lipogenesis and ROS Production, and Induces Mitochondrial Dysfunction
Open the PDF for FTO Is Increased in Muscle During Type 2 Diabetes, and Its Overexpression in Myotubes Alters Insulin Signaling, Enhances Lipogenesis and ROS Production, and Induces Mitochondrial Dysfunction in another window
Includes: Supplementary data
Journal Articles

The microRNA Signature in Response to Insulin Reveals Its Implication in the Transcriptional Action of Insulin in Human Skeletal Muscle and the Role of a Sterol Regulatory Element–Binding Protein-1c/Myocyte Enhancer Factor 2C Pathway

Aurélie Granjon, Marie-Paule Gustin, Jennifer Rieusset, Etienne Lefai, Emmanuelle Meugnier, Isabelle Güller, Catherine Cerutti, Christian Paultre, Emmanuel Disse, Rémi Rabasa-Lhoret, Martine Laville, Hubert Vidal, Sophie Rome
Journal: Diabetes
Diabetes 2009;58(11):2555–2564
https://doi.org/10.2337/db09-0165
Published: 31 August 2009
View articletitled, The microRNA Signature in Response to Insulin Reveals Its Implication in the Transcriptional Action of Insulin in Human Skeletal Muscle and the Role of a Sterol Regulatory Element–Binding Protein-1c/Myocyte Enhancer Factor 2C Pathway
Open the PDF for The microRNA Signature in Response to Insulin Reveals Its Implication in the Transcriptional Action of Insulin in Human Skeletal Muscle and the Role of a Sterol Regulatory Element–Binding Protein-1c/Myocyte Enhancer Factor 2C Pathway in another window
Includes: Supplementary data
Journal Articles

Sterol Regulatory Element-Binding Protein-1 Mediates the Effect of Insulin on Hexokinase II Gene Expression in Human Muscle Cells

Yvan Gosmain, Etienne Lefai, Stephan Ryser, Marina Roques, Hubert Vidal
Journal: Diabetes
Diabetes 2004;53(2):321–329
https://doi.org/10.2337/diabetes.53.2.321
Published: 01 February 2004
View articletitled, Sterol Regulatory Element-Binding Protein-1 Mediates the Effect of Insulin on Hexokinase II Gene Expression in Human Muscle Cells
Open the PDF for Sterol Regulatory Element-Binding Protein-1 Mediates the Effect of Insulin on Hexokinase II Gene Expression in Human Muscle Cells in another window