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Meeting Abstracts

1112-P: Soluble Suppression of Tumorigenicity 2 Is Directly Correlated with Body Fat, Metabolic Dysfunction, and Inflammation in Children and Adolescents

AMAL HASAN, SHIHAB P. KOCHUMON, IMAN D. ALBASIRI, FAHD ALMULLA, RASHEED AHMAD

Diabetes 2023;72(Supplement_1):1112-P

https://doi.org/10.2337/db23-1112-P

Published: 20 June 2023

View article titled, 1112-P: Soluble Suppression of Tumorigenicity 2 Is Directly Correlated with Body Fat, Metabolic Dysfunction, and Inflammation in Children and Adolescents

Meeting Abstracts

1603-P: Differential Effects of Cocoa Butter, Sunflower, Soybean, and Fish Oil Based Sucrose-Free HFDs on Hepatic Steatosis, Lipogenesis, Inflammation, and Insulin Resistance in Mice

RASHEED AHMAD, TEXY K. JACOB, SHIHAB P. KOCHUMON, REEBY S. THOMAS, STEVE SHENOUDA, NADEEM AKHTER, AJIT WILSON, FATEMAH BAHMAN, AMAL HASAN, FATEMA ALRASHED, HOSSEIN AREFANIAN, ASHRAF AL MADHOUN, FAHD ALMULLA, SARDAR T.A.K. SINDHU

Diabetes 2023;72(Supplement_1):1603-P

https://doi.org/10.2337/db23-1603-P

Published: 20 June 2023

View article titled, 1603-P: Differential Effects of Cocoa Butter, Sunflower, Soybean, and Fish Oil Based Sucrose-Free HFDs on Hepatic Steatosis, Lipogenesis, Inflammation, and Insulin Resistance in Mice

Meeting Abstracts

1491-P: ER Stress Drives the VEGF Expression in Monocytic Cells by Mechanisms Involving CHOP/ROS/HIF-1alpha/NRF2 and NF-kappaB/p38 MAPK Pathways

SARDAR A.K. SINDHU, NADEEM AKHTER, AJIT WILSON, HOSSEIN AREFANIAN, ASHRAF AL MADHOUN, REEBY S. THOMAS, SHIHAB P. KOCHUMON, FATEMA ALRASHED, FATEMAH BAHMAN, FAWAZ ALZAID, FAHD ALMULLA, RASHEED AHMAD

Diabetes 2023;72(Supplement_1):1491-P

https://doi.org/10.2337/db23-1491-P

Published: 20 June 2023

View article titled, 1491-P: ER Stress Drives the VEGF Expression in Monocytic Cells by Mechanisms Involving CHOP/ROS/HIF-1alpha/NRF2 and NF-kappaB/p38 MAPK Pathways

Meeting Abstracts

41-LB: Regular Physical Activity Plays a Crucial Role in Improving the Anti-inflammatory Status of Healthy Individuals by Modulating TLR2 Expression

FATEMAH BAHMAN, HALEMAH ALSAEED, SHAIMA ALBELOUSHI, FAHD ALMULLA, RASHEED AHMAD, FATEMA ALRASHED

Diabetes 2023;72(Supplement_1):41-LB

https://doi.org/10.2337/db23-41-LB

Published: 20 June 2023

View article titled, 41-LB: Regular Physical Activity Plays a Crucial Role in Improving the Anti-inflammatory Status of Healthy Individuals by Modulating TLR2 Expression

Meeting Abstracts

1480-P: Mitochondrial Haplogroup H Is Protective against Type 2 Diabetes in Arabs from Gulf Region

MOHAMMED H. DASHTI, NASER ALI, HUSSAIN ALSALEH, RASHEEBA NIZAM, FAHD ALMULLA, ALPHONSE T. THANGAVEL

Diabetes 2023;72(Supplement_1):1480-P

https://doi.org/10.2337/db23-1480-P

Published: 20 June 2023

View article titled, 1480-P: Mitochondrial Haplogroup H Is Protective against Type 2 Diabetes in Arabs from Gulf Region

Meeting Abstracts

173-LB: Circulating Calprotectin Is Increased in Children with T1D and Obesity—Implications for T1D Progression and Outcome

AMAL HASAN, SHIHAB P. KOCHUMON, IMAN D. ALBASIRI, SHAIMA ALBELOUSHI, EBAA S. ALOZAIRI, FAHD ALMULLA

Diabetes 2023;72(Supplement_1):173-LB

https://doi.org/10.2337/db23-173-LB

Published: 20 June 2023

View article titled, 173-LB: Circulating Calprotectin Is Increased in Children with T1D and Obesity—Implications for T1D Progression and Outcome

Meeting Abstracts

1690-P: Adipose Tissue Dectin-1 Upregulation in Hyperglycemic Obesity Involves TNF-α/NF-kB Mediated Signaling

ASHRAF AL MADHOUN, DANIA HADDAD, SHIHAB P. KOCHUMON, FATEMA ALRASHED, REEBY S. THOMAS, LAVINA P. MIRANDA, SARDAR T.A.K. SINDHU, RASHEED AHMAD, FAHD ALMULLA

Diabetes 2023;72(Supplement_1):1690-P

https://doi.org/10.2337/db23-1690-P

Published: 20 June 2023

View article titled, 1690-P: Adipose Tissue Dectin-1 Upregulation in Hyperglycemic Obesity Involves TNF-α/NF-kB Mediated Signaling

Meeting Abstracts

1763-P: Pretreatment with Verapamil Increases MIN6 Mouse ß-Cell Survival after Exposure to Cytotoxic Stressors

Diabetes 2023;72(Supplement_1):1763-P

https://doi.org/10.2337/db23-1763-P

Published: 20 June 2023

View article titled, 1763-P: Pretreatment with Verapamil Increases MIN6 Mouse ß-Cell Survival after Exposure to Cytotoxic Stressors

Meeting Abstracts

1762-P: Increased Glucose Sensing and Insulin Secretion Induced by Verapamil Is Associated with Enhanced Oxygen Consumption Rate in MIN6 ß-Cells

Diabetes 2023;72(Supplement_1):1762-P

https://doi.org/10.2337/db23-1762-P

Published: 20 June 2023

View article titled, 1762-P: Increased Glucose Sensing and Insulin Secretion Induced by Verapamil Is Associated with Enhanced Oxygen Consumption Rate in MIN6 ß-Cells

Meeting Abstracts

1761-P: Verapamil Increases ß-Cells Proliferation in MIN6 Cells and ß-Cell Mass in Zebrafish Model

Diabetes 2023;72(Supplement_1):1761-P

https://doi.org/10.2337/db23-1761-P

Published: 20 June 2023

View article titled, 1761-P: Verapamil Increases ß-Cells Proliferation in MIN6 Cells and ß-Cell Mass in Zebrafish Model

Meeting Abstracts

54-LB: Distinct Mechanisms Are Responsible for the Increase in Endogenous Glucose Production and Ketone Formation following Empagliflozin in T2DM Patients

SIHAM ABDELGANI, JOHN M. ADAMS, III, GIUSEPPE DANIELE, FAHD ALMULLA, RALPH A. DEFRONZO, MUHAMMAD ABDUL-GHANI, MOHAMED ABU-FARHA, STEFANO DEL PRATO

Diabetes 2022;71(Supplement_1):54-LB

https://doi.org/10.2337/db22-54-LB

Published: 01 June 2022

View article titled, 54-LB: Distinct Mechanisms Are Responsible for the Increase in Endogenous Glucose Production and Ketone Formation following Empagliflozin in T2DM Patients

Meeting Abstracts

1270-P: ICA1 Is Differentially Methylated and Expressed in Familial Type 1 Diabetes

MOHAMMED H. DASHTI, RASHEEBA NIZAM, PRASHANTHA HEBBAR, SINDHU JACOB, SUMI E. JOHN, ARSHAD M. CHANNANATH, SR., HESSA ALKANDARI, ALPHONSE T. THANGAVEL, FAHD ALMULLA

Diabetes 2022;71(Supplement_1):1270-P

https://doi.org/10.2337/db22-1270-P

Published: 01 June 2022

View article titled, 1270-P: ICA1 Is Differentially Methylated and Expressed in Familial Type 1 Diabetes

Meeting Abstracts

1434-P: ANGPTL8 Variant R59W Is Associated with Increased Circulatory TNF-alpha and IL7 LEVELS and Inflammation

ANWAR MOHAMMAD, MOHAMED ABU-FARHA, DHANYA MADHU, PREETHI T. CHERIAN, IRINA AL KHAIRI, PRASHANTHA HEBBAR, SINA A. KAVALAKATT, HOSSEIN AREFANIAN, NADA ALAM-ELDIN, ALPHONSE T. THANGAVEL, FAHD ALMULLA, JEHAD ABUBAKER

Diabetes 2022;71(Supplement_1):1434-P

https://doi.org/10.2337/db22-1434-P

Published: 01 June 2022

View article titled, 1434-P: ANGPTL8 Variant R59W Is Associated with Increased Circulatory TNF-alpha and IL7 LEVELS and Inflammation

Meeting Abstracts

1279-P: Caveolin 1 rs1997623 Is Associated with Metabolic Syndrome in Arab Adult Individuals from Kuwait

ASHRAF AL MADHOUN, PRASHANTHA HEBBAR, RASHEEBA NIZAM, DANIA HADDAD, MOHAMMED H. DASHTI, MOHAMED ABU-FARHA, RASHEED AHMAD, ALPHONSE T. THANGAVEL, FAHD ALMULLA

Diabetes 2022;71(Supplement_1):1279-P

https://doi.org/10.2337/db22-1279-P

Published: 01 June 2022

View article titled, 1279-P: Caveolin 1 rs1997623 Is Associated with Metabolic Syndrome in Arab Adult Individuals from Kuwait

Meeting Abstracts

1278-P: The Tale of Caveolin 1 rs1997623 Variant in Obesity and Metabolic Syndrome

ASHRAF AL MADHOUN, DANIA HADDAD, SHIHAB P. KOCHUMON, RASHEEBA NIZAM, SINDHU JACOB, SARDAR T. SINDHU, RASHEED AHMAD, FAHD ALMULLA

Diabetes 2022;71(Supplement_1):1278-P

https://doi.org/10.2337/db22-1278-P

Published: 01 June 2022

View article titled, 1278-P: The Tale of Caveolin 1 rs1997623 Variant in Obesity and Metabolic Syndrome

Meeting Abstracts

211-OR: Plasma Insulin Is Required for the Increase in Plasma ANGPTL8 Concentration following Glucose Ingestion

MOHAMED ABU-FARHA, JEHAD ABUBAKER, IRINA AL KHAIRI, PREETHI T. CHERIAN, CHRISTINA AGYIN, IV, SIHAM ABDELGANI, EBAA S. ALOZAIRI, JOHN M. ADAMS, II, FAHD ALMULLA, RALPH A. DEFRONZO, MUHAMMAD ABDUL-GHANI

Diabetes 2022;71(Supplement_1):211-OR

https://doi.org/10.2337/db22-211-OR

Published: 01 June 2022

View article titled, 211-OR: Plasma Insulin Is Required for the Increase in Plasma ANGPTL8 Concentration following Glucose Ingestion

Meeting Abstracts

478-P: GALNT2 Variant Associates with Increased ANGPTL3 Circulation Level and Obesity

ALPHONSE T. THANGAVEL, MOHAMED ABU-FARHA, PRASHANTHA HEBBAR, MOHAMMAD G. QADDOUMI, FAHD ALMULLA, JEHAD ABUBAKER

Diabetes 2022;71(Supplement_1):478-P

https://doi.org/10.2337/db22-478-P

Published: 01 June 2022

View article titled, 478-P: GALNT2 Variant Associates with Increased ANGPTL3 Circulation Level and Obesity

Meeting Abstracts

1288-P: Increased Adipose Tissue Expression of IL-23 and Its Association with Inflammation in Individuals with High LDL Cholesterol

RASHEED AHMAD, SHIHAB P. KOCHUMON, AMAL HASAN, SARDAR T. SINDHU, HOSSEIN AREFANIAN, FATEMA ALRASHED, FAHD ALMULLA

Diabetes 2022;71(Supplement_1):1288-P

https://doi.org/10.2337/db22-1288-P

Published: 01 June 2022

View article titled, 1288-P: Increased Adipose Tissue Expression of IL-23 and Its Association with Inflammation in Individuals with High LDL Cholesterol

Meeting Abstracts

75-OR: IL-6R (Trans Signaling) Is a Major Modulator of Reverse Cholesterol Transport in Lipid-Laden Macrophages

FATEMA ALRASHED, FATEMAH ALZAQQAH, ASHRAF AL MADHOUN, RAWAN ALQABANDI, SARDAR T. SINDHU, FAHD ALMULLA, RASHEED AHMAD

Diabetes 2022;71(Supplement_1):75-OR

https://doi.org/10.2337/db22-75-OR

Published: 01 June 2022

View article titled, 75-OR: IL-6R (Trans Signaling) Is a Major Modulator of Reverse Cholesterol Transport in Lipid-Laden Macrophages

Meeting Abstracts

1139-P: CD36/FABP4/PPAR-d Axis-Induced Inflammation Is Dependent on ACSL1 under the Influence of Acute High-Fat Feeding

FATEMA ALRASHED, ASHRAF AL MADHOUN, SARDAR T. SINDHU, AMNAH AL-SAYYAR, FAHD ALMULLA, RASHEED AHMAD

Diabetes 2021;70(Supplement_1):1139-P

https://doi.org/10.2337/db21-1139-P

Published: 01 June 2021

View article titled, 1139-P: CD36/FABP4/PPAR-d Axis-Induced Inflammation Is Dependent on ACSL1 under the Influence of Acute High-Fat Feeding

NARROW

1112-P: Soluble Suppression of Tumorigenicity 2 Is Directly Correlated with Body Fat, Metabolic Dysfunction, and Inflammation in Children and Adolescents

1603-P: Differential Effects of Cocoa Butter, Sunflower, Soybean, and Fish Oil Based Sucrose-Free HFDs on Hepatic Steatosis, Lipogenesis, Inflammation, and Insulin Resistance in Mice

1491-P: ER Stress Drives the VEGF Expression in Monocytic Cells by Mechanisms Involving CHOP/ROS/HIF-1alpha/NRF2 and NF-kappaB/p38 MAPK Pathways

41-LB: Regular Physical Activity Plays a Crucial Role in Improving the Anti-inflammatory Status of Healthy Individuals by Modulating TLR2 Expression

1480-P: Mitochondrial Haplogroup H Is Protective against Type 2 Diabetes in Arabs from Gulf Region

173-LB: Circulating Calprotectin Is Increased in Children with T1D and Obesity—Implications for T1D Progression and Outcome

1690-P: Adipose Tissue Dectin-1 Upregulation in Hyperglycemic Obesity Involves TNF-α/NF-kB Mediated Signaling

1763-P: Pretreatment with Verapamil Increases MIN6 Mouse ß-Cell Survival after Exposure to Cytotoxic Stressors

1762-P: Increased Glucose Sensing and Insulin Secretion Induced by Verapamil Is Associated with Enhanced Oxygen Consumption Rate in MIN6 ß-Cells

1761-P: Verapamil Increases ß-Cells Proliferation in MIN6 Cells and ß-Cell Mass in Zebrafish Model

54-LB: Distinct Mechanisms Are Responsible for the Increase in Endogenous Glucose Production and Ketone Formation following Empagliflozin in T2DM Patients

1270-P: ICA1 Is Differentially Methylated and Expressed in Familial Type 1 Diabetes

1434-P: ANGPTL8 Variant R59W Is Associated with Increased Circulatory TNF-alpha and IL7 LEVELS and Inflammation

1279-P: Caveolin 1 rs1997623 Is Associated with Metabolic Syndrome in Arab Adult Individuals from Kuwait

1278-P: The Tale of Caveolin 1 rs1997623 Variant in Obesity and Metabolic Syndrome

211-OR: Plasma Insulin Is Required for the Increase in Plasma ANGPTL8 Concentration following Glucose Ingestion

478-P: GALNT2 Variant Associates with Increased ANGPTL3 Circulation Level and Obesity

1288-P: Increased Adipose Tissue Expression of IL-23 and Its Association with Inflammation in Individuals with High LDL Cholesterol

75-OR: IL-6R (Trans Signaling) Is a Major Modulator of Reverse Cholesterol Transport in Lipid-Laden Macrophages

1139-P: CD36/FABP4/PPAR-d Axis-Induced Inflammation Is Dependent on ACSL1 under the Influence of Acute High-Fat Feeding

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