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Journal Articles

SKAP2, a Candidate Gene for Type 1 Diabetes, Regulates β-Cell Apoptosis and Glycemic Control in Newly Diagnosed Patients

Tina Fløyel, Kira Meyerovich, Michala C. Prause, Simranjeet Kaur, Caroline Frørup, Henrik B. Mortensen, Lotte B. Nielsen, Flemming Pociot, Alessandra K. Cardozo, Joachim Størling

Diabetes 2021;70(2):464–476

https://doi.org/10.2337/db20-0092

Published: 17 November 2020

View article titled, SKAP2, a Candidate Gene for Type 1 Diabetes, Regulates β-Cell Apoptosis and Glycemic Control in Newly Diagnosed Patients

Journal Articles

TYK2, a Candidate Gene for Type 1 Diabetes, Modulates Apoptosis and the Innate Immune Response in Human Pancreatic β-Cells

Laura Marroqui, Reinaldo Sousa Dos Santos, Tina Fløyel, Fabio A. Grieco, Izortze Santin, Anne Op de beeck, Lorella Marselli, Piero Marchetti, Flemming Pociot, Decio L. Eizirik

Diabetes 2015;64(11):3808–3817

https://doi.org/10.2337/db15-0362

Published: 03 August 2015

View article titled, TYK2, a Candidate Gene for Type 1 Diabetes, Modulates Apoptosis and the Innate Immune Response in Human Pancreatic β-Cells

Includes: Supplementary data

Journal Articles

Novel Association Between Immune-Mediated Susceptibility Loci and Persistent Autoantibody Positivity in Type 1 Diabetes

Caroline A. Brorsson, Suna Onengut, Wei-Min Chen, Janet Wenzlau, Liping Yu, Peter Baker, Alistair J.K. Williams, Polly J. Bingley, John C. Hutton, George S. Eisenbarth, Patrick Concannon, Stephen S. Rich, Flemming Pociot, for the Type 1 Diabetes Genetics Consortium

Diabetes 2015;64(8):3017–3027

https://doi.org/10.2337/db14-1730

Published: 31 March 2015

View article titled, Novel Association Between Immune-Mediated Susceptibility Loci and Persistent Autoantibody Positivity in Type 1 Diabetes

Includes: Supplementary data

Journal Articles

Evidence of Gene-Gene Interaction and Age-at-Diagnosis Effects in Type 1 Diabetes

Joanna M.M. Howson, Jason D. Cooper, Deborah J. Smyth, Neil M. Walker, Helen Stevens, Jin-Xiong She, George S. Eisenbarth, Marian Rewers, John A. Todd, Beena Akolkar, Patrick Concannon, Henry A. Erlich, Cécile Julier, Grant Morahan, Jørn Nerup, Concepcion Nierras, Flemming Pociot, Stephen S. Rich, and the Type 1 Diabetes Genetics Consortium

Diabetes 2012;61(11):3012–3017

https://doi.org/10.2337/db11-1694

Published: 16 October 2012

View article titled, Evidence of Gene-Gene Interaction and Age-at-Diagnosis Effects in Type 1 Diabetes

Includes: Supplementary data

Journal Articles

Identification of Novel Type 1 Diabetes Candidate Genes by Integrating Genome-Wide Association Data, Protein-Protein Interactions, and Human Pancreatic Islet Gene Expression

Regine Bergholdt, Caroline Brorsson, Albert Palleja, Lukas A. Berchtold, Tina Fløyel, Claus Heiner Bang-Berthelsen, Klaus Stensgaard Frederiksen, Lars Juhl Jensen, Joachim Størling, Flemming Pociot

Diabetes 2012;61(4):954–962

https://doi.org/10.2337/db11-1263

Published: 14 March 2012

View article titled, Identification of Novel Type 1 Diabetes Candidate Genes by Integrating Genome-Wide Association Data, Protein-Protein Interactions, and Human Pancreatic Islet Gene Expression

Includes: Supplementary data

Journal Articles

Tests for Genetic Interactions in Type 1 Diabetes: Linkage and Stratification Analyses of 4,422 Affected Sib-Pairs

Grant Morahan, Munish Mehta, Ian James, Wei-Min Chen, Beena Akolkar, Henry A. Erlich, Joan E. Hilner, Cécile Julier, Jørn Nerup, Concepcion Nierras, Flemming Pociot, John A. Todd, Stephen S. Rich, for the Type 1 Diabetes Genetics Consortium

Diabetes 2011;60(3):1030–1040

https://doi.org/10.2337/db10-1195

Published: 21 February 2011

View article titled, Tests for Genetic Interactions in Type 1 Diabetes: <subtitle>Linkage and Stratification Analyses of 4,422 Affected Sib-Pairs</subtitle>

Includes: Supplementary data

Journal Articles

Genetics of Type 1 Diabetes: What's Next?

Flemming Pociot, Beena Akolkar, Patrick Concannon, Henry A. Erlich, Cécile Julier, Grant Morahan, Concepcion R. Nierras, John A. Todd, Stephen S. Rich, Jørn Nerup

Diabetes 2010;59(7):1561–1571

https://doi.org/10.2337/db10-0076

Published: 01 July 2010

View article titled, Genetics of Type 1 Diabetes: What's Next?

Journal Articles

Genome-Wide Scan for Linkage to Type 1 Diabetes in 2,496 Multiplex Families From the Type 1 Diabetes Genetics Consortium

Patrick Concannon, Wei-Min Chen, Cécile Julier, Grant Morahan, Beena Akolkar, Henry A. Erlich, Joan E. Hilner, Jørn Nerup, Concepcion Nierras, Flemming Pociot, John A. Todd, Stephen S. Rich, the Type 1 Diabetes Genetics Consortium

Diabetes 2009;58(4):1018–1022

https://doi.org/10.2337/db08-1551

Published: 09 January 2009

View article titled, Genome-Wide Scan for Linkage to Type 1 Diabetes in 2,496 Multiplex Families From the Type 1 Diabetes Genetics Consortium

Includes: Supplementary data

Journal Articles

A Human Type 1 Diabetes Susceptibility Locus Maps to Chromosome 21q22.3

Patrick Concannon, Suna Onengut-Gumuscu, John A. Todd, Deborah J. Smyth, Flemming Pociot, Regine Bergholdt, Beena Akolkar, Henry A. Erlich, Joan E. Hilner, Cécile Julier, Grant Morahan, Jørn Nerup, Concepcion R. Nierras, Wei-Min Chen, Stephen S. Rich, the Type 1 Diabetes Genetics Consortium

Diabetes 2008;57(10):2858–2861

https://doi.org/10.2337/db08-0753

Published: 01 October 2008

View article titled, A Human Type 1 Diabetes Susceptibility Locus Maps to Chromosome 21q22.3

Journal Articles

PTPN22 R620W Functional Variant in Type 1 Diabetes and Autoimmunity Related Traits

Claude Chelala, Sabine Duchatelet, Marie-Line Joffret, Regine Bergholdt, Danièle Dubois-Laforgue, Pegah Ghandil, Flemming Pociot, Sophie Caillat-Zucman, José Timsit, Cécile Julier

Diabetes 2007;56(2):522–526

https://doi.org/10.2337/db06-0942

Published: 01 February 2007

View article titled, PTPN22 R620W Functional Variant in Type 1 Diabetes and Autoimmunity Related Traits

Includes: Supplementary data

Journal Articles

Type 1 Diabetes: Evidence for Susceptibility Loci from Four Genome-Wide Linkage Scans in 1,435 Multiplex Families

Patrick Concannon, Henry A. Erlich, Cecile Julier, Grant Morahan, Jørn Nerup, Flemming Pociot, John A. Todd, Stephen S. Rich, the Type 1 Diabetes Genetics Consortium

Diabetes 2005;54(10):2995–3001

https://doi.org/10.2337/diabetes.54.10.2995

Published: 01 October 2005

View article titled, Type 1 Diabetes: <subtitle>Evidence for Susceptibility Loci from Four Genome-Wide Linkage Scans in 1,435 Multiplex Families</subtitle>

Includes: Supplementary data

Journal Articles

OAS1 Splice Site Polymorphism Controlling Antiviral Enzyme Activity Influences Susceptibility to Type 1 Diabetes

L. Leigh Field, Vagn Bonnevie-Nielsen, Flemming Pociot, Shao Lu, Thomas B. Nielsen, Henning Beck-Nielsen

Diabetes 2005;54(5):1588–1591

https://doi.org/10.2337/diabetes.54.5.1588

Published: 01 May 2005

View article titled, OAS1 Splice Site Polymorphism Controlling Antiviral Enzyme Activity Influences Susceptibility to Type 1 Diabetes

Journal Articles

Linkage and Association Between a CD4 Gene Polymorphism and IDDM in Danish IDDM Patients

Ole Peter Kristiansen, Mahdi Zamani, Jesper Johannesen, Thomas Mandrup-Poulsen, Jean-Jacques Cassiman, Jørn Nerup, Flemming Pociot, The Danish IDDM Epidemiology and Genetics Group, and The Danish Study Group of Diabetes in Childhood

Diabetes 1998;47(2):281–283

https://doi.org/10.2337/diab.47.2.281

Published: 01 February 1998

View article titled, Linkage and Association Between a CD4 Gene Polymorphism and IDDM in Danish IDDM Patients

Journal Articles

Polymorphisms in the Interleukin-1 Gene Cluster Do Not Contribute to the Genetic Susceptibility of Diabetic Nephropathy in Caucasian Patients With IDDM

Lise Tarnow, Flemming Pociot, Pernille M Hansen, Peter Rossing, Flemming S Nielsen, Birgitte V Hansen, Hans-Henrik Parving

Diabetes 1997;46(6):1075–1076

https://doi.org/10.2337/diab.46.6.1075

Published: 01 June 1997

View article titled, Polymorphisms in the Interleukin-1 Gene Cluster Do Not Contribute to the Genetic Susceptibility of Diabetic Nephropathy in Caucasian Patients With IDDM

Journal Articles

Strain-Dependent Differences in Sensitivity of Rat β-Cells to Interleukin 1β In Vitro and In Vivo

Jesper I Reimers, Herik U Anderson, Dídac Mauricio, Flemming Pociot, Allan Karlsen, Jacob S Peterson, Thomas Mandrup-Poulsen, Jørn Nerup

Diabetes 1996;45(6):771–778

https://doi.org/10.2337/diab.45.6.771

Published: 01 June 1996

View article titled, Strain-Dependent Differences in Sensitivity of Rat β-Cells to Interleukin 1β In Vitro and In Vivo

Journal Articles

Monokine Antagonism Is Reduced in Patients With IDDM

Thomas Mandrup-Poulsen, Flemming Pociot, Jens Mølvig, Leland Shapiro, Povl Nilsson, Torkil Emdal, Michael Røder, Lisa L Kjems, Charles A Dinarello, Jørn Nerup

Diabetes 1994;43(10):1242–1247

https://doi.org/10.2337/diab.43.10.1242

Published: 01 October 1994

View article titled, Monokine Antagonism Is Reduced in Patients With IDDM

Journal Articles

Major Histocompatibility Complex–Encoded Antigen Processing Gene Polymorphism in IDDM

Peter M Van Endert, Roland S Liblau, Salil D Patel, Lars Fugger, Theresa Lopez, Flemming Pociot, Jørn Nerup, Hugh O McDevitt

Diabetes 1994;43(1):110–117

https://doi.org/10.2337/diab.43.1.110

Published: 01 January 1994

View article titled, Major Histocompatibility Complex–Encoded Antigen Processing Gene Polymorphism in IDDM

NARROW

SKAP2, a Candidate Gene for Type 1 Diabetes, Regulates β-Cell Apoptosis and Glycemic Control in Newly Diagnosed Patients

TYK2, a Candidate Gene for Type 1 Diabetes, Modulates Apoptosis and the Innate Immune Response in Human Pancreatic β-Cells

Novel Association Between Immune-Mediated Susceptibility Loci and Persistent Autoantibody Positivity in Type 1 Diabetes

Evidence of Gene-Gene Interaction and Age-at-Diagnosis Effects in Type 1 Diabetes

Identification of Novel Type 1 Diabetes Candidate Genes by Integrating Genome-Wide Association Data, Protein-Protein Interactions, and Human Pancreatic Islet Gene Expression

Tests for Genetic Interactions in Type 1 Diabetes: Linkage and Stratification Analyses of 4,422 Affected Sib-Pairs

Genetics of Type 1 Diabetes: What's Next?

Genome-Wide Scan for Linkage to Type 1 Diabetes in 2,496 Multiplex Families From the Type 1 Diabetes Genetics Consortium

A Human Type 1 Diabetes Susceptibility Locus Maps to Chromosome 21q22.3

PTPN22 R620W Functional Variant in Type 1 Diabetes and Autoimmunity Related Traits

Type 1 Diabetes: Evidence for Susceptibility Loci from Four Genome-Wide Linkage Scans in 1,435 Multiplex Families

OAS1 Splice Site Polymorphism Controlling Antiviral Enzyme Activity Influences Susceptibility to Type 1 Diabetes

Linkage and Association Between a CD4 Gene Polymorphism and IDDM in Danish IDDM Patients

Polymorphisms in the Interleukin-1 Gene Cluster Do Not Contribute to the Genetic Susceptibility of Diabetic Nephropathy in Caucasian Patients With IDDM

Strain-Dependent Differences in Sensitivity of Rat β-Cells to Interleukin 1β In Vitro and In Vivo

Monokine Antagonism Is Reduced in Patients With IDDM

Major Histocompatibility Complex–Encoded Antigen Processing Gene Polymorphism in IDDM

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