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Folkert Kuipers
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Journal Articles

Hyperinsulinemia Is Highly Associated With Markers of Hepatocytic Senescence in Two Independent Cohorts

Free
Abraham S. Meijnikman, Casper C. van Olden, Ömrüm Aydin, Hilde Herrema, Dorota Kaminska, Dimitra Lappa, Ville Männistö, Valentina Tremaroli, Louise E. Olofsson, Maurits de Brauw, Arnold van de Laar, Joanne Verheij, Victor E.A. Gerdes, Thue W. Schwartz, Jens Nielsen, Fredrik Bäckhed, Päivi Pajukanta, Jussi Pihlajamäki, Tamar Tchkonia, James L. Kirkland, Folkert Kuipers, Max Nieuwdorp, Albert K. Groen
Journal: Diabetes
Diabetes 2022;71(9):1929–1936
https://doi.org/10.2337/db21-1076
Published: 17 June 2022
View articletitled, Hyperinsulinemia Is Highly Associated With Markers of Hepatocytic Senescence in Two Independent Cohorts
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Journal Articles

Farnesoid X Receptor Deficiency Improves Glucose Homeostasis in Mouse Models of Obesity

Open Access
Janne Prawitt, Mouaadh Abdelkarim, Johanna H.M. Stroeve, Iuliana Popescu, Helene Duez, Vidya R. Velagapudi, Julie Dumont, Emmanuel Bouchaert, Theo H. van Dijk, Anthony Lucas, Emilie Dorchies, Mehdi Daoudi, Sophie Lestavel, Frank J. Gonzalez, Matej Oresic, Bertrand Cariou, Folkert Kuipers, Sandrine Caron, Bart Staels
Journal: Diabetes
Diabetes 2011;60(7):1861–1871
https://doi.org/10.2337/db11-0030
Published: 20 June 2011
View articletitled, Farnesoid X Receptor Deficiency Improves Glucose Homeostasis in Mouse Models of Obesity
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Includes: Supplementary data
Journal Articles

Pharmacological Inhibition of Glucosylceramide Synthase Enhances Insulin Sensitivity

Free
Johannes M. Aerts, Roelof Ottenhoff, Andrew S. Powlson, Aldo Grefhorst, Marco van Eijk, Peter F. Dubbelhuis, Jan Aten, Folkert Kuipers, Mireille J. Serlie, Tom Wennekes, Jaswinder K. Sethi, Stephen O'Rahilly, Hermen S. Overkleeft
Journal: Diabetes
Diabetes 2007;56(5):1341–1349
https://doi.org/10.2337/db06-1619
Published: 01 May 2007
View articletitled, Pharmacological Inhibition of Glucosylceramide Synthase Enhances Insulin Sensitivity
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Includes: Supplementary data
Journal Articles

Peroxisome Proliferator–Activated Receptor α Improves Pancreatic Adaptation to Insulin Resistance in Obese Mice and Reduces Lipotoxicity in Human Islets

Free
Fanny Lalloyer, Brigitte Vandewalle, Frédéric Percevault, Gérard Torpier, Julie Kerr-Conte, Maaike Oosterveer, Réjane Paumelle, Jean-Charles Fruchart, Folkert Kuipers, François Pattou, Catherine Fiévet, Bart Staels
Journal: Diabetes
Diabetes 2006;55(6):1605–1613
https://doi.org/10.2337/db06-0016
Published: 01 June 2006
View articletitled, Peroxisome Proliferator–Activated Receptor α Improves Pancreatic Adaptation to Insulin Resistance in Obese Mice and Reduces Lipotoxicity in Human Islets
Open the PDF for Peroxisome Proliferator–Activated Receptor α Improves Pancreatic Adaptation to Insulin Resistance in Obese Mice and Reduces Lipotoxicity in Human Islets in another window
Includes: Supplementary data
Journal Articles

Glucose Regulates the Expression of the Farnesoid X Receptor in Liver

Free
Daniel Duran-Sandoval, Gisèle Mautino, Geneviève Martin, Fréderic Percevault, Olivier Barbier, Jean-Charles Fruchart, Folkert Kuipers, Bart Staels
Journal: Diabetes
Diabetes 2004;53(4):890–898
https://doi.org/10.2337/diabetes.53.4.890
Published: 01 April 2004
View articletitled, Glucose Regulates the Expression of the Farnesoid X Receptor in Liver
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Journal Articles

Hepatic VLDL Production in ob/ob Mice Is Not Stimulated by Massive De Novo Lipogenesis but Is Less Sensitive to the Suppressive Effects of Insulin

Free
Coen H. Wiegman, Robert H.J. Bandsma, Margriet Ouwens, Fjodor H. van der Sluijs, Rick Havinga, Theo Boer, Dirk-Jan Reijngoud, Johannes A. Romijn, Folkert Kuipers
Journal: Diabetes
Diabetes 2003;52(5):1081–1089
https://doi.org/10.2337/diabetes.52.5.1081
Published: 01 May 2003
View articletitled, Hepatic VLDL Production in ob/ob Mice Is Not Stimulated by Massive De Novo Lipogenesis but Is Less Sensitive to the Suppressive Effects of Insulin
Open the PDF for Hepatic VLDL Production in ob/ob Mice Is Not Stimulated by Massive De Novo Lipogenesis but Is Less Sensitive to the Suppressive Effects of Insulin in another window
Journal Articles

Acute Inhibition of Glucose-6-Phosphate Translocator Activity Leads to Increased De Novo Lipogenesis and Development of Hepatic Steatosis Without Affecting VLDL Production in Rats

Free
Robert H.J. Bandsma, Coen H. Wiegman, Andreas W. Herling, Hans-Joerg Burger, Anke ter Harmsel, Alfred J. Meijer, Johannes A. Romijn, Dirk-Jan Reijngoud, Folkert Kuipers
Journal: Diabetes
Diabetes 2001;50(11):2591–2597
https://doi.org/10.2337/diabetes.50.11.2591
Published: 01 November 2001
View articletitled, Acute Inhibition of Glucose-6-Phosphate Translocator Activity Leads to Increased De Novo Lipogenesis and Development of Hepatic Steatosis Without Affecting VLDL Production in Rats
Open the PDF for Acute Inhibition of Glucose-6-Phosphate Translocator Activity Leads to Increased De Novo Lipogenesis and Development of Hepatic Steatosis Without Affecting VLDL Production in Rats in another window