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Meeting Abstracts

1693-P: Irisin Levels, Glycometabolic Characteristics, and Muscle Performance in Type 2 Diabetes Patients with Sarcopenic or Nonsarcopenic Obesity

ERICA ROSSI, LUDOVICO DI GIOIA, NICOLA MARRANO, SEBASTIO PERRINI, LUIGI LAVIOLA, ANNALISA NATALICCHIO, FRANCESCO GIORGINO
Journal: Diabetes
Diabetes 2024;73(Supplement_1):1693-P
https://doi.org/10.2337/db24-1693-P
Published: 14 June 2024
View articletitled, 1693-P: Irisin Levels, Glycometabolic Characteristics, and Muscle Performance in Type 2 Diabetes Patients with Sarcopenic or Nonsarcopenic Obesity
Meeting Abstracts

783-P: Efficacy of GLP-1RA according to Type 2 Diabetes Phenotypes—A Monocentric Retrospective Study

IRENE CARUSO, FIORELLA GIORDANO, LUDOVICO DI GIOIA, IMMACOLATA I. MATICHECCHIA, ANGELO CIGNARELLI, GIAN PIO SORICE, SEBASTIO PERRINI, ANNALISA NATALICCHIO, LUIGI LAVIOLA, FRANCESCO GIORGINO
Journal: Diabetes
Diabetes 2024;73(Supplement_1):783-P
https://doi.org/10.2337/db24-783-P
Published: 14 June 2024
View articletitled, 783-P: Efficacy of GLP-1RA according to Type 2 Diabetes Phenotypes—A Monocentric Retrospective Study
Meeting Abstracts

438-P: Glucose-Dependent Insulinotropic Polypeptide Prevents Palmitate-Induced Apoptosis, but Not Autophagy and Stress Kinase Activation in Human Cardiac Progenitor Cells

ISABELLA CALDERONI, ROSSELLA DORIA, CRISTINA CACCIOPPOLI, CARMELA COLABUFO, VALENTINA ANNAMARIA GENCHI, GIUSEPPE PALMA, GIUSEPPE SANTARPINO, ALDO D. MILANO, TOMASO BOTTIO, ANNA LEONARDINI, ANNALISA NATALICCHIO, SEBASTIO PERRINI, ANGELO CIGNARELLI, FRANCESCO GIORGINO, LUIGI LAVIOLA
Journal: Diabetes
Diabetes 2024;73(Supplement_1):438-P
https://doi.org/10.2337/db24-438-P
Published: 14 June 2024
View articletitled, 438-P: Glucose-Dependent Insulinotropic Polypeptide Prevents Palmitate-Induced Apoptosis, but Not Autophagy and Stress Kinase Activation in Human Cardiac Progenitor Cells
Meeting Abstracts

307-OR: Defective G-CSF in the Secretome of Epicardial Adipose Cells Favors Apoptosis and Cellular Stress of Cardiac Progenitor Cells in Human Obesity

GIUSEPPE PALMA, CRISTINA CACCIOPPOLI, ROSSELLA DORIA, VALENTINA ANNAMARIA GENCHI, ISABELLA CALDERONI, TOMASO BOTTIO, GIUSEPPE SANTARPINO, ANGELO CIGNARELLI, ANNALISA NATALICCHIO, LUIGI LAVIOLA, ANGELA PEZZOLLA, ANGELA M. VALVERDE, ALDO D. MILANO, FRANCESCO GIORGINO, SEBASTIO PERRINI
Journal: Diabetes
Diabetes 2024;73(Supplement_1):307-OR
https://doi.org/10.2337/db24-307-OR
Published: 14 June 2024
View articletitled, 307-OR: Defective G-CSF in the Secretome of Epicardial Adipose Cells Favors Apoptosis and Cellular Stress of Cardiac Progenitor Cells in Human Obesity
Meeting Abstracts

1867-LB: A Real-World Study Assessing the Efficacy and Safety of Switching from Basal–Bolus Insulin Therapy to Once-Daily iGlarLixi in People with Type 2 Diabetes—Soli De-escalation

FRANCESCO GIORGINO, FELIPE LAUAND, SR., SORALY SERVERA, XUAN LI, ZOLTÁN TAYBANI, ALICE Y.Y. CHENG, VIVIAN FONSECA, AMAR TEBAIBIA, INAN ANAFOROGLU
Journal: Diabetes
Diabetes 2024;73(Supplement_1):1867-LB
https://doi.org/10.2337/db24-1867-LB
Published: 14 June 2024
View articletitled, 1867-LB: A Real-World Study Assessing the Efficacy and Safety of Switching from Basal–Bolus Insulin Therapy to Once-Daily iGlarLixi in People with Type 2 Diabetes—Soli De-escalation
Meeting Abstracts

777-P: Early Weight Loss and Late Metabolic Outcomes in Tirzepatide-Treated Participants with Type 2 Diabetes

ILDIKO LINGVAY, FRANCESCO GIORGINO, LUC VAN GAAL, MINZHI LIU, ÁNGEL RODRÍGUEZ, AMELIA TORCELLO-GOMEZ, JACEK I. KILJANSKI
Journal: Diabetes
Diabetes 2023;72(Supplement_1):777-P
https://doi.org/10.2337/db23-777-P
Published: 20 June 2023
View articletitled, 777-P: Early Weight Loss and Late Metabolic Outcomes in Tirzepatide-Treated Participants with Type 2 Diabetes
Meeting Abstracts

773-P: Consistent Glycemic Efficacy and Safety of Concomitant Use of iGlarLixi and Sodium–Glucose Cotransporter-2 Inhibitor Therapy for Type 2 Diabetes—A Patient-Level Pooled Analysis

FRANCESCO GIORGINO, CRISTIAN GUJA, MELANIE J. DAVIES, HASAN AYDIN, FELIPE LAUAND, ELISABETH SOUHAMI, LYDIE MELAS-MELT, VANITA R. ARODA, JULIO ROSENSTOCK
Journal: Diabetes
Diabetes 2023;72(Supplement_1):773-P
https://doi.org/10.2337/db23-773-P
Published: 20 June 2023
View articletitled, 773-P: Consistent Glycemic Efficacy and Safety of Concomitant Use of iGlarLixi and Sodium–Glucose Cotransporter-2 Inhibitor Therapy for Type 2 Diabetes—A Patient-Level Pooled Analysis
Meeting Abstracts

772-P: Tirzepatide vs. Basal Insulins in People with T2D and Different Baseline Glycemic Patterns—Post Hoc Analyses of the SURPASS-3 and -4 Trials

FRANCESCO GIORGINO, DENISE R. FRANCO, CLAUDIA NICOLAY, ANDREA HEMMINGWAY, ÁNGEL RODRÍGUEZ, RUSSELL WIESE
Journal: Diabetes
Diabetes 2023;72(Supplement_1):772-P
https://doi.org/10.2337/db23-772-P
Published: 20 June 2023
View articletitled, 772-P: Tirzepatide vs. Basal Insulins in People with T2D and Different Baseline Glycemic Patterns—Post Hoc Analyses of the SURPASS-3 and -4 Trials
Meeting Abstracts

38-OR: Insulin Prevents Palmitate-Induced Stress Kinase Activation, Autophagy, and Apoptosis in Human Cardiac Progenitor Cells

ISABELLA CALDERONI, ROSSELLA DORIA, CRISTINA CACCIOPPOLI, VALENTINA ANNAMARIA GENCHI, GIUSEPPE PALMA, GIUSEPPE SANTARPINO, ALDO D. MILANO, ANNA LEONARDINI, ANNALISA NATALICCHIO, SEBASTIO PERRINI, ANGELO CIGNARELLI, FRANCESCO GIORGINO, LUIGI LAVIOLA
Journal: Diabetes
Diabetes 2023;72(Supplement_1):38-OR
https://doi.org/10.2337/db23-38-OR
Published: 20 June 2023
View articletitled, 38-OR: Insulin Prevents Palmitate-Induced Stress Kinase Activation, Autophagy, and Apoptosis in Human Cardiac Progenitor Cells
Meeting Abstracts

246-OR: Dapagliflozin Counteracts the Proapoptotic Effects of the Secretome of Visceral Adipose Cells from Obese Subjects in Human Cardiac Progenitor Cells via the SGLT2 Cotransporter

GIUSEPPE PALMA, CRISTINA CACCIOPPOLI, ROSSELLA DORIA, VALENTINA ANNAMARIA GENCHI, ISABELLA CALDERONI, ANTONIO BRAUN, GIUSEPPE SANTARPINO, ALDO D. MILANO, ANGELO CIGNARELLI, ANNALISA NATALICCHIO, LUIGI LAVIOLA, ANGELA PEZZOLLA, FRANCESCO GIORGINO, SEBASTIO PERRINI
Journal: Diabetes
Diabetes 2023;72(Supplement_1):246-OR
https://doi.org/10.2337/db23-246-OR
Published: 20 June 2023
View articletitled, 246-OR: Dapagliflozin Counteracts the Proapoptotic Effects of the Secretome of Visceral Adipose Cells from Obese Subjects in Human Cardiac Progenitor Cells via the SGLT2 Cotransporter
Meeting Abstracts

1661-P: The Myokine Irisin Is Endocytosed and Signals through an αV Integrin-Independent Mechanism in Pancreatic ß-Cells

NICOLA MARRANO, ANNA BORRELLI, GIUSEPPINA BIONDI, MARTINA RELLA, ANGELO CIGNARELLI, SEBASTIO PERRINI, LUIGI LAVIOLA, FRANCESCO GIORGINO, ANNALISA NATALICCHIO
Journal: Diabetes
Diabetes 2023;72(Supplement_1):1661-P
https://doi.org/10.2337/db23-1661-P
Published: 20 June 2023
View articletitled, 1661-P: The Myokine Irisin Is Endocytosed and Signals through an αV Integrin-Independent Mechanism in Pancreatic ß-Cells
Meeting Abstracts

981-P: Transition from Standard Time to Daylight Saving Time and Vice Versa—Effects on FGM Metrics in Patients with Autoimmune Diabetes

LUDOVICO DI GIOIA, SERGIO DI MOLFETTA, FIORELLA GIORDANO, MARIANGELA CAPORUSSO, GIAN PIO SORICE, ANGELO CIGNARELLI, ANNALISA NATALICCHIO, LUIGI LAVIOLA, FRANCESCO GIORGINO
Journal: Diabetes
Diabetes 2023;72(Supplement_1):981-P
https://doi.org/10.2337/db23-981-P
Published: 20 June 2023
View articletitled, 981-P: Transition from Standard Time to Daylight Saving Time and Vice Versa—Effects on FGM Metrics in Patients with Autoimmune Diabetes
Journal Articles

The p66Shc Protein Mediates Insulin Resistance and Secretory Dysfunction in Pancreatic β-Cells Under Lipotoxic Conditions

Giuseppina Biondi, Nicola Marrano, Lucia Dipaola, Anna Borrelli, Martina Rella, Rossella D’Oria, Valentina A. Genchi, Cristina Caccioppoli, Immacolata Porreca, Angelo Cignarelli, Sebastio Perrini, Piero Marchetti, Leonardo Vincenti, Luigi Laviola, Francesco Giorgino, Annalisa Natalicchio
Journal: Diabetes
Diabetes 2022;71(8):1763–1771
https://doi.org/10.2337/db21-1066
Published: 21 August 2022
View articletitled, The p66Shc Protein Mediates Insulin Resistance and Secretory Dysfunction in Pancreatic β-Cells Under Lipotoxic Conditions
Open the PDF for The p66Shc Protein Mediates Insulin Resistance and Secretory Dysfunction in Pancreatic β-Cells Under Lipotoxic Conditions in another window
Meeting Abstracts

729-P: Relationship between Body Weight Change and Glycemic Control with Tirzepatide Treatment in People with Type 2 Diabetes

SUE PEDERSEN, GUILLERMO E. UMPIERREZ, FRANCESCO GIORGINO, ÁNGEL RODRÍGUEZ, VIVIAN THIEU, HELENE SAPIN, LAURA FERNANDEZ LANDO, CHRISANTHI A. KARANIKAS, JACEK I. KILJANSKI
Journal: Diabetes
Diabetes 2022;71(Supplement_1):729-P
https://doi.org/10.2337/db22-729-P
Published: 01 June 2022
View articletitled, 729-P: Relationship between Body Weight Change and Glycemic Control with Tirzepatide Treatment in People with Type 2 Diabetes
Meeting Abstracts

885-P: Real-World Evidence on Health Care Costs Related to Self-Monitoring of Blood Glucose (SMBG) Compared with Continuous Glucose Monitoring (CGM) in Nonintensively Treated Type 2 Diabetes Mellitus (T2DM)

DAVID KERR, IAN DUNCAN, FRANCESCO GIORGINO, ENRICO REPETTO, CHRISTOPHER PERKINS, RANA MAROUN, MEREDITH RIVERS, ALEXANDER WU
Journal: Diabetes
Diabetes 2022;71(Supplement_1):885-P
https://doi.org/10.2337/db22-885-P
Published: 01 June 2022
View articletitled, 885-P: Real-World Evidence on Health Care Costs Related to Self-Monitoring of Blood Glucose (SMBG) Compared with Continuous Glucose Monitoring (CGM) in Nonintensively Treated Type 2 Diabetes Mellitus (T2DM)
Meeting Abstracts

833-P: Impact of Hypoglycemia on Insulin Titration and Fasting Plasma Glucose in Basal Insulin–Treated Type 2 Diabetes: A Subanalysis of the SoliMix Trial

FRANCESCO GIORGINO, JULIO ROSENSTOCK, ROBERT RITZEL, OGUZHAN DEYNELI, AGUSTINA ALVAREZ, ELISABETH SOUHAMI, LYDIE MELAS-MELT, RORY J. MCCRIMMON
Journal: Diabetes
Diabetes 2022;71(Supplement_1):833-P
https://doi.org/10.2337/db22-833-P
Published: 01 June 2022
View articletitled, 833-P: Impact of Hypoglycemia on Insulin Titration and Fasting Plasma Glucose in Basal Insulin–Treated Type 2 Diabetes: A Subanalysis of the SoliMix Trial
Meeting Abstracts

726-P: The Real-World Observational Prospective Study of Health Outcomes with Dulaglutide and Liraglutide in Type 2 Diabetes Patients (TROPHIES) : Final 24-Month Clinical Characteristics and Treatment Pattern Analyses

BRUNO GUERCI, FRANCESCO GIORGINO, KRISTINA BOYE, MARTIN FUECHTENBUSCH, ELKE HEITMANN, JEREMIE LEBREC, ANNE DIB, MARCO ORSINI FEDERICI, MARIA YU, LUIS-EMILIO GARCIA-PEREZ
Journal: Diabetes
Diabetes 2022;71(Supplement_1):726-P
https://doi.org/10.2337/db22-726-P
Published: 01 June 2022
View articletitled, 726-P: The Real-World Observational Prospective Study of Health Outcomes with Dulaglutide and Liraglutide in Type 2 Diabetes Patients (TROPHIES) : Final 24-Month Clinical Characteristics and Treatment Pattern Analyses
Meeting Abstracts

441-P: Oleate Prevents Palmitate-Induced Abnormalities in Insulin Signaling in Human Cardiac Progenitor Cells by Inhibiting p38 MAPK and c-Jun Phosphorylation

ROSSELLA DORIA, ISABELLA CALDERONI, CRISTINA CACCIOPPOLI, VALENTINA ANNAMARIA GENCHI, GIUSEPPE SANTARPINO, ANNA LEONARDINI, ANNALISA NATALICCHIO, SEBASTIO PERRINI, ANGELO CIGNARELLI, FRANCESCO GIORGINO, LUIGI LAVIOLA
Journal: Diabetes
Diabetes 2022;71(Supplement_1):441-P
https://doi.org/10.2337/db22-441-P
Published: 01 June 2022
View articletitled, 441-P: Oleate Prevents Palmitate-Induced Abnormalities in Insulin Signaling in Human Cardiac Progenitor Cells by Inhibiting p38 MAPK and c-Jun Phosphorylation
Meeting Abstracts

1061-P: Need for Insulin Therapy in Gestational Diabetes Mellitus: A Predictive Model Assessment

MARIANGELA CAPORUSSO, LUDOVICO DI GIOIA, GIAN PIO SORICE, ANGELO CIGNARELLI, ANNALISA NATALICCHIO, FRANCESCO GIORGINO, LUIGI LAVIOLA
Journal: Diabetes
Diabetes 2022;71(Supplement_1):1061-P
https://doi.org/10.2337/db22-1061-P
Published: 01 June 2022
View articletitled, 1061-P: Need for Insulin Therapy in Gestational Diabetes Mellitus: A Predictive Model Assessment
Meeting Abstracts

1375-P: Effects of Irisin Administration on Pancreatic Islets of Diabetic Mice

NICOLA MARRANO, GIUSEPPINA BIONDI, ANNA BORRELLI, LUCA ROBERTO, ANGELO CIGNARELLI, SEBASTIO PERRINI, LUIGI LAVIOLA, FRANCESCO GIORGINO, ANNALISA NATALICCHIO
Journal: Diabetes
Diabetes 2022;71(Supplement_1):1375-P
https://doi.org/10.2337/db22-1375-P
Published: 01 June 2022
View articletitled, 1375-P: Effects of Irisin Administration on Pancreatic Islets of Diabetic Mice