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Frans Schuit
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Journal Articles

GPCR Promiscuity Reshapes Islet Physiology

Frans Schuit, Jonathan E. Campbell
Journal: Diabetes
Diabetes 2023;72(9):1180–1183
https://doi.org/10.2337/dbi23-0014
Published: 21 August 2023
View article titled, GPCR Promiscuity Reshapes Islet Physiology
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Journal Articles

Loss of Furin in β-Cells Induces an mTORC1-ATF4 Anabolic Pathway That Leads to β-Cell Dysfunction

Bas Brouwers, Ilaria Coppola, Katlijn Vints, Bastian Dislich, Nathalie Jouvet, Leentje Van Lommel, Charlotte Segers, Natalia V. Gounko, Lieven Thorrez, Frans Schuit, Stefan F. Lichtenthaler, Jennifer L. Estall, Jeroen Declercq, Bruno Ramos-Molina, John W.M. Creemers
Journal: Diabetes
Diabetes 2021;70(2):492–503
https://doi.org/10.2337/db20-0474
Published: 04 December 2020
View article titled, Loss of <em>Furin</em> in β-Cells Induces an mTORC1-ATF4 Anabolic Pathway That Leads to β-Cell Dysfunction
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Journal Articles

Potential of Protein Phosphatase Inhibitor 1 As Biomarker of Pancreatic β-Cell Injury In Vitro and In Vivo

Lei Jiang, Benedicte Brackeva, Zhidong Ling, Gertjan Kramer, Johannes M. Aerts, Frans Schuit, Bart Keymeulen, Daniel Pipeleers, Frans Gorus, Geert A. Martens
Journal: Diabetes
Diabetes 2013;62(8):2683–2688
https://doi.org/10.2337/db12-1507
Published: 17 July 2013
View article titled, Potential of Protein Phosphatase Inhibitor 1 As Biomarker of Pancreatic β-Cell Injury In Vitro and In Vivo
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Includes: Supplementary data
Journal Articles

Response to Comment on: Schuit et al. β-Cell–Specific Gene Repression: A Mechanism to Protect Against Inappropriate or Maladjusted Insulin Secretion? Diabetes 2012;61:969–975

Frans Schuit
Journal: Diabetes
Diabetes 2012;61(10):e17
https://doi.org/10.2337/db12-0888
Published: 13 September 2012
View article titled, Response to Comment on: Schuit et al. β-Cell–Specific Gene Repression: A Mechanism to Protect Against Inappropriate or Maladjusted Insulin Secretion? Diabetes 2012;61:969–975
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Journal Articles

β-Cell–Specific Gene Repression: A Mechanism to Protect Against Inappropriate or Maladjusted Insulin Secretion?

Frans Schuit, Leentje Van Lommel, Mikaela Granvik, Lotte Goyvaerts, Geoffroy de Faudeur, Anica Schraenen, Katleen Lemaire
Journal: Diabetes
Diabetes 2012;61(5):969–975
https://doi.org/10.2337/db11-1564
Published: 13 April 2012
View article titled, β-Cell–Specific Gene Repression: A Mechanism to Protect Against Inappropriate or Maladjusted Insulin Secretion?
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Journal Articles

A Glucose Sensor Role for Glucokinase in Anterior Pituitary Cells

Dorothy Zelent, Maria L. Golson, Brigitte Koeberlein, Roel Quintens, Leentje van Lommel, Carol Buettger, Heather Weik-Collins, Rebecca Taub, Joseph Grimsby, Frans Schuit, Klaus H. Kaestner, Franz M. Matschinsky
Journal: Diabetes
Diabetes 2006;55(7):1923–1929
https://doi.org/10.2337/db06-0151
Published: 01 July 2006
View article titled, A Glucose Sensor Role for Glucokinase in Anterior Pituitary Cells
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Journal Articles

Essential Role of Chicken Ovalbumin Upstream Promoter-Transcription Factor II in Insulin Secretion and Insulin Sensitivity Revealed by Conditional Gene Knockout

Pascale Bardoux, Pili Zhang, Daisy Flamez, Anaïs Perilhou, Tiphaine Aguirre Lavin, Jean-François Tanti, Karine Hellemans, Emmanuel Gomas, Cécile Godard, Fabrizio Andreelli, Maria Antonietta Buccheri, Axel Kahn, Yannick Le Marchand-Brustel, Rémy Burcelin, Frans Schuit, Mireille Vasseur-Cognet
Journal: Diabetes
Diabetes 2005;54(5):1357–1363
https://doi.org/10.2337/diabetes.54.5.1357
Published: 01 May 2005
View article titled, Essential Role of Chicken Ovalbumin Upstream Promoter-Transcription Factor II in Insulin Secretion and Insulin Sensitivity Revealed by Conditional Gene Knockout
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Journal Articles

Double Incretin Receptor Knockout (DIRKO) Mice Reveal an Essential Role for the Enteroinsular Axis in Transducing the Glucoregulatory Actions of DPP-IV Inhibitors

Tanya Hansotia, Laurie L. Baggio, Dominique Delmeire, Simon A. Hinke, Yuichiro Yamada, Katsushi Tsukiyama, Yutaka Seino, Jens J. Holst, Frans Schuit, D.J. Drucker
Journal: Diabetes
Diabetes 2004;53(5):1326–1335
https://doi.org/10.2337/diabetes.53.5.1326
Published: 01 May 2004
View article titled, Double Incretin Receptor Knockout (DIRKO) Mice Reveal an Essential Role for the Enteroinsular Axis in Transducing the Glucoregulatory Actions of DPP-IV Inhibitors
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Journal Articles

Variations in IB1/JIP1 Expression Regulate Susceptibility of β-Cells to Cytokine-Induced Apoptosis Irrespective of C-Jun NH2-Terminal Kinase Signaling

Zhidong Ling, Mark Van de Casteele, Jing Dong, Harry Heimberg, Jacques-Antoine Haefliger, Gérard Waeber, Frans Schuit, Daniel Pipeleers
Journal: Diabetes
Diabetes 2003;52(10):2497–2502
https://doi.org/10.2337/diabetes.52.10.2497
Published: 01 October 2003
View article titled, Variations in IB1/JIP1 Expression Regulate Susceptibility of β-Cells to Cytokine-Induced Apoptosis Irrespective of C-Jun NH<sub>2</sub>-Terminal Kinase Signaling
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Journal Articles

Glucose-Regulated Gene Expression Maintaining the Glucose-Responsive State of β-Cells

Frans Schuit, Daisy Flamez, Anick De Vos, Daniel Pipeleers
Journal: Diabetes
Diabetes 2002;51(suppl_3):S326–S332
https://doi.org/10.2337/diabetes.51.2007.S326
Published: 01 December 2002
View article titled, Glucose-Regulated Gene Expression Maintaining the Glucose-Responsive State of β-Cells
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Journal Articles

Assessment of the Role of Interstitial Glucagon in the Acute Glucose Secretory Responsiveness of In Situ Pancreatic β-Cells

Karen Moens, Veerle Berger, Jung-Mo Ahn, Chris Van Schravendijk, Victor J. Hruby, Daniel Pipeleers, Frans Schuit
Journal: Diabetes
Diabetes 2002;51(3):669–675
https://doi.org/10.2337/diabetes.51.3.669
Published: 01 March 2002
View article titled, Assessment of the Role of Interstitial Glucagon in the Acute Glucose Secretory Responsiveness of In Situ Pancreatic β-Cells
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Journal Articles

Dual Glucagon Recognition by Pancreatic β-Cells via Glucagon and Glucagon-Like Peptide 1 Receptors

Karen Moens, Daisy Flamez, Chris Van Schravendijk, Zhidong Ling, Daniel Pipeleers, Frans Schuit
Journal: Diabetes
Diabetes 1998;47(1):66–72
https://doi.org/10.2337/diab.47.1.66
Published: 01 January 1998
View article titled, Dual Glucagon Recognition by Pancreatic β-Cells via Glucagon and Glucagon-Like Peptide 1 Receptors
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Journal Articles

TNFa Microsatellite Polymorphism Modulates the Risk of IDDM in Caucasians With the High-Risk Genotype HLA DQA1*0501-DQB1*0201/DQA1*0301-DQB1*0302

Payman Hanifi Moghaddam, Aeilko H Zwinderman, Peter de Knijff, Bart O Roep, Ron F Schipper, Bart Van der Auwera, Albert Naipal, Frans Gorus, Frans Schuit, Marius J Giphart, Belgian Diabetes Registry
Journal: Diabetes
Diabetes 1997;46(9):1514–1515
https://doi.org/10.2337/diab.46.9.1514
Published: 01 September 1997
View article titled, TNFa Microsatellite Polymorphism Modulates the Risk of IDDM in Caucasians With the High-Risk Genotype HLA DQA1*0501-DQB1*0201/DQA1*0301-DQB1*0302
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Journal Articles

Expression and Functional Activity of Glucagon, Glucagon-Like Peptide I, and Glucose-Dependent Insulinotropic Peptide Receptors in Rat Pancreatic Islet Cells

Karen Moens, Harry Heimberg, Daisy Flamez, Peter Huypens, Erik Quartier, Zhidong Ling, Daniel Pipeleers, Sandrine Gremlich, Bernard Thorens, Frans Schuit
Journal: Diabetes
Diabetes 1996;45(2):257–261
https://doi.org/10.2337/diab.45.2.257
Published: 01 February 1996
View article titled, Expression and Functional Activity of Glucagon, Glucagon-Like Peptide I, and Glucose-Dependent Insulinotropic Peptide Receptors in Rat Pancreatic Islet Cells
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Journal Articles

DRB1*0403 Protects Against IDDM in Caucasians With the High-Risk Heterozygous DQA1*0301-DQB1*0302/DQA1*0501-DQB1*0201 Genotype

Bart Van der Auwera, Christine Van Waeyenberge, Frans Schuit, Harry Heimberg, Christina Vandewalle, Frans Gorus, Jocelyne Flament, Belgian Diabetes Registry
Journal: Diabetes
Diabetes 1995;44(5):527–530
https://doi.org/10.2337/diab.44.5.527
Published: 01 May 1995
View article titled, DRB1*0403 Protects Against IDDM in Caucasians With the High-Risk Heterozygous DQA1*0301-DQB1*0302/DQA1*0501-DQB1*0201 Genotype
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