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Journal Articles

Functional and Metabolomic Consequences of K_ATP Channel Inactivation in Human Islets

Changhong Li, Amanda M. Ackermann, Kara E. Boodhansingh, Tricia R. Bhatti, Chengyang Liu, Jonathan Schug, Nicolai Doliba, Bing Han, Karen E. Cosgrove, Indraneel Banerjee, Franz M. Matschinsky, Itzhak Nissim, Klaus H. Kaestner, Ali Naji, N. Scott Adzick, Mark J. Dunne, Charles A. Stanley, Diva D. De León

Diabetes 2017;66(7):1901–1913

https://doi.org/10.2337/db17-0029

Published: 25 April 2017

View article titled, Functional and Metabolomic Consequences of KATP Channel Inactivation in Human Islets

Includes: Supplementary data

Journal Articles

Susceptibility of Glucokinase-MODY Mutants to Inactivation by Oxidative Stress in Pancreatic β-Cells

Kirsty S. Cullen, Franz M. Matschinsky, Loranne Agius, Catherine Arden

Diabetes 2011;60(12):3175–3185

https://doi.org/10.2337/db11-0423

Published: 13 November 2011

View article titled, Susceptibility of Glucokinase-MODY Mutants to Inactivation by Oxidative Stress in Pancreatic β-Cells

Includes: Supplementary data

Journal Articles

Extremes of Clinical and Enzymatic Phenotypes in Children With Hyperinsulinism Caused by Glucokinase Activating Mutations

Samir Sayed, David R. Langdon, Stella Odili, Pan Chen, Carol Buettger, Alisa B. Schiffman, Mariko Suchi, Rebecca Taub, Joseph Grimsby, Franz M. Matschinsky, Charles A. Stanley

Diabetes 2009;58(6):1419–1427

https://doi.org/10.2337/db08-1792

Published: 31 March 2009

View article titled, Extremes of Clinical and Enzymatic Phenotypes in Children With Hyperinsulinism Caused by Glucokinase Activating Mutations

Journal Articles

Cell Biology Assessment of Glucokinase Mutations V62M and G72R in Pancreatic β-Cells: Evidence for Cellular Instability of Catalytic Activity

Catherine Arden, Alison Trainer, Nuria de la Iglesia, Kathleen T. Scougall, Anna L. Gloyn, Alex J. Lange, James A.M. Shaw, Franz M. Matschinsky, Loranne Agius

Diabetes 2007;56(7):1773–1782

https://doi.org/10.2337/db06-1151

Published: 01 July 2007

View article titled, Cell Biology Assessment of Glucokinase Mutations V62M and G72R in Pancreatic β-Cells: <subtitle>Evidence for Cellular Instability of Catalytic Activity</subtitle>

Journal Articles

Foxa1-Deficient Mice Exhibit Impaired Insulin Secretion due to Uncoupled Oxidative Phosphorylation

Marko Z. Vatamaniuk, Rana K. Gupta, Kristen A. Lantz, Nicolai M. Doliba, Franz M. Matschinsky, Klaus H. Kaestner

Diabetes 2006;55(10):2730–2736

https://doi.org/10.2337/db05-0470

Published: 01 October 2006

View article titled, Foxa1-Deficient Mice Exhibit Impaired Insulin Secretion due to Uncoupled Oxidative Phosphorylation

Journal Articles

Retraction

Franz M. Matschinsky

Diabetes 2006;55(9):2664

https://doi.org/10.2337/db06-rt09

Published: 01 September 2006

View article titled, Retraction

Journal Articles

A Glucose Sensor Role for Glucokinase in Anterior Pituitary Cells

Dorothy Zelent, Maria L. Golson, Brigitte Koeberlein, Roel Quintens, Leentje van Lommel, Carol Buettger, Heather Weik-Collins, Rebecca Taub, Joseph Grimsby, Frans Schuit, Klaus H. Kaestner, Franz M. Matschinsky

Diabetes 2006;55(7):1923–1929

https://doi.org/10.2337/db06-0151

Published: 01 July 2006

View article titled, A Glucose Sensor Role for Glucokinase in Anterior Pituitary Cells

Journal Articles

From Clinicogenetic Studies of Maturity-Onset Diabetes of the Young to Unraveling Complex Mechanisms of Glucokinase Regulation

Jørn V. Sagen, Stella Odili, Lise Bjørkhaug, Dorothy Zelent, Carol Buettger, Jae Kwagh, Charles Stanley, Knut Dahl-Jørgensen, Carine de Beaufort, Graeme I. Bell, Yi Han, Joseph Grimsby, Rebecca Taub, Anders Molven, Oddmund Søvik, Pål R. Njølstad, Franz M. Matschinsky

Diabetes 2006;55(6):1713–1722

https://doi.org/10.2337/db05-1513

Published: 01 June 2006

View article titled, From Clinicogenetic Studies of Maturity-Onset Diabetes of the Young to Unraveling Complex Mechanisms of Glucokinase Regulation

Journal Articles

The Network of Glucokinase-Expressing Cells in Glucose Homeostasis and the Potential of Glucokinase Activators for Diabetes Therapy

Franz M. Matschinsky, Mark A. Magnuson, Dorothy Zelent, Tom L. Jetton, Nicolai Doliba, Yi Han, Rebecca Taub, Joseph Grimsby

Diabetes 2006;55(1):1–12

https://doi.org/10.2337/diabetes.55.01.06.db05-0926

Published: 01 January 2006

View article titled, The Network of Glucokinase-Expressing Cells in Glucose Homeostasis and the Potential of Glucokinase Activators for Diabetes Therapy

Journal Articles

Retraction

Franz M. Matschinsky

Diabetes 2005;54(7):2266

https://doi.org/10.2337/diabetes.54.7.2266

Published: 01 July 2005

View article titled, Retraction

Journal Articles

Structural and Functional Abnormalities in the Islets Isolated From Type 2 Diabetic Subjects

Shaoping Deng, Marko Vatamaniuk, Xiaolun Huang, Nicolai Doliba, Moh-Moh Lian, Adam Frank, Ergun Velidedeoglu, Niraj M. Desai, Brigitte Koeberlein, Bryan Wolf, Clyde F. Barker, Ali Naji, Franz M. Matschinsky, James F. Markmann

Diabetes 2004;53(3):624–632

https://doi.org/10.2337/diabetes.53.3.624

Published: 01 March 2004

View article titled, Structural and Functional Abnormalities in the Islets Isolated From Type 2 Diabetic Subjects

Journal Articles

Rapamycin Has a Deleterious Effect on MIN-6 Cells and Rat and Human Islets

Ewan Bell, Xiaopei Cao, Jacob A. Moibi, Scott R. Greene, Robert Young, Matteo Trucco, Zhiyong Gao, Franz M. Matschinsky, Shaoping Deng, James F. Markman, Ali Naji, Bryan A. Wolf

Diabetes 2003;52(11):2731–2739

https://doi.org/10.2337/diabetes.52.11.2731

Published: 01 November 2003

View article titled, Rapamycin Has a Deleterious Effect on MIN-6 Cells and Rat and Human Islets

Journal Articles

Permanent Neonatal Diabetes Caused by Glucokinase Deficiency: Inborn Error of the Glucose-Insulin Signaling Pathway

Pål R. Njølstad, Jørn V. Sagen, Lise Bjørkhaug, Stella Odili, Naim Shehadeh, Doua Bakry, S. Umit Sarici, Faruk Alpay, Janne Molnes, Anders Molven, Oddmund Søvik, Franz M. Matschinsky

Diabetes 2003;52(11):2854–2860

https://doi.org/10.2337/diabetes.52.11.2854

Published: 01 November 2003

View article titled, Permanent Neonatal Diabetes Caused by Glucokinase Deficiency: <subtitle>Inborn Error of the Glucose-Insulin Signaling Pathway</subtitle>

Journal Articles

Insights Into the Biochemical and Genetic Basis of Glucokinase Activation From Naturally Occurring Hypoglycemia Mutations

Anna L. Gloyn, Kees Noordam, Michèl A.A.P. Willemsen, Sian Ellard, Wayne W.K. Lam, Ian W. Campbell, Paula Midgley, Chyio Shiota, Carol Buettger, Mark A. Magnuson, Franz M. Matschinsky, Andrew T. Hattersley

Diabetes 2003;52(9):2433–2440

https://doi.org/10.2337/diabetes.52.9.2433

Published: 01 September 2003

View article titled, Insights Into the Biochemical and Genetic Basis of Glucokinase Activation From Naturally Occurring Hypoglycemia Mutations

Journal Articles

Differential Effects of Glucose and Glyburide on Energetics and Na⁺ Levels of βHC9 Cells: Nuclear Magnetic Resonance Spectroscopy and Respirometry Studies

Nicolai M. Doliba, Marko Z. Vatamaniuk, Carol W. Buettger, Wei Qin, Heather W. Collins, Suzanne L. Wehrli, Richard D. Carr, Franz M. Matschinsky

Diabetes 2003;52(2):394–402

https://doi.org/10.2337/diabetes.52.2.394

Published: 01 February 2003

View article titled, Differential Effects of Glucose and Glyburide on Energetics and Na+ Levels of βHC9 Cells: <subtitle>Nuclear Magnetic Resonance Spectroscopy and Respirometry Studies </subtitle>

Journal Articles

Regulation of Pancreatic β-Cell Glucokinase: From Basics to Therapeutics

Franz M. Matschinsky

Diabetes 2002;51(suppl_3):S394–S404

https://doi.org/10.2337/diabetes.51.2007.S394

Published: 01 December 2002

View article titled, Regulation of Pancreatic β-Cell Glucokinase: <subtitle>From Basics to Therapeutics </subtitle>

Journal Articles

Glutaminolysis and Insulin Secretion: From Bedside to Bench and Back

Andrea Kelly, Changhong Li, Zhiyong Gao, Charles A. Stanley, Franz M. Matschinsky

Diabetes 2002;51(suppl_3):S421–S426

https://doi.org/10.2337/diabetes.51.2007.S421

Published: 01 December 2002

View article titled, Glutaminolysis and Insulin Secretion: <subtitle>From Bedside to Bench and Back </subtitle>

Journal Articles

Foxa2 Controls Pdx1 Gene Expression in Pancreatic β-Cells In Vivo

Catherine S. Lee, Newman J. Sund, Marko Z. Vatamaniuk, Franz M. Matschinsky, Doris A. Stoffers, Klaus H. Kaestner

Diabetes 2002;51(8):2546–2551

https://doi.org/10.2337/diabetes.51.8.2546

Published: 01 August 2002

View article titled, Foxa2 Controls Pdx1 Gene Expression in Pancreatic β-Cells In Vivo

Journal Articles

The Second Activating Glucokinase Mutation (A456V): Implications for Glucose Homeostasis and Diabetes Therapy

Henrik B.T. Christesen, Bendt B. Jacobsen, Stella Odili, Carol Buettger, Antonio Cuesta-Munoz, Torben Hansen, Klaus Brusgaard, Ornella Massa, Mark A. Magnuson, Chiyo Shiota, Franz M. Matschinsky, Fabrizio Barbetti

Diabetes 2002;51(4):1240–1246

https://doi.org/10.2337/diabetes.51.4.1240

Published: 01 April 2002

View article titled, The Second Activating Glucokinase Mutation (A456V): <subtitle>Implications for Glucose Homeostasis and Diabetes Therapy </subtitle>

Journal Articles

Wortmannin Inhibits Insulin Secretion in Pancreatic Islets and β-TC3 Cells Independent of Its Inhibition of Phosphatidylinositol 3-Kinase

Zhi-yong Gao, Robert J Konrad, Heather Collins, Franz M Matschinsky, Paul L Rothenberg, Bryan A Wolf

Diabetes 1996;45(7):854–862

https://doi.org/10.2337/diab.45.7.854

Published: 01 July 1996

View article titled, Wortmannin Inhibits Insulin Secretion in Pancreatic Islets and β-TC3 Cells Independent of Its Inhibition of Phosphatidylinositol 3-Kinase

NARROW

Functional and Metabolomic Consequences of K_ATP Channel Inactivation in Human Islets

Susceptibility of Glucokinase-MODY Mutants to Inactivation by Oxidative Stress in Pancreatic β-Cells

Extremes of Clinical and Enzymatic Phenotypes in Children With Hyperinsulinism Caused by Glucokinase Activating Mutations

Cell Biology Assessment of Glucokinase Mutations V62M and G72R in Pancreatic β-Cells: Evidence for Cellular Instability of Catalytic Activity

Foxa1-Deficient Mice Exhibit Impaired Insulin Secretion due to Uncoupled Oxidative Phosphorylation

Retraction

A Glucose Sensor Role for Glucokinase in Anterior Pituitary Cells

From Clinicogenetic Studies of Maturity-Onset Diabetes of the Young to Unraveling Complex Mechanisms of Glucokinase Regulation

The Network of Glucokinase-Expressing Cells in Glucose Homeostasis and the Potential of Glucokinase Activators for Diabetes Therapy

Retraction

Structural and Functional Abnormalities in the Islets Isolated From Type 2 Diabetic Subjects

Rapamycin Has a Deleterious Effect on MIN-6 Cells and Rat and Human Islets

Permanent Neonatal Diabetes Caused by Glucokinase Deficiency: Inborn Error of the Glucose-Insulin Signaling Pathway

Insights Into the Biochemical and Genetic Basis of Glucokinase Activation From Naturally Occurring Hypoglycemia Mutations

Differential Effects of Glucose and Glyburide on Energetics and Na⁺ Levels of βHC9 Cells: Nuclear Magnetic Resonance Spectroscopy and Respirometry Studies

Regulation of Pancreatic β-Cell Glucokinase: From Basics to Therapeutics

Glutaminolysis and Insulin Secretion: From Bedside to Bench and Back

Foxa2 Controls Pdx1 Gene Expression in Pancreatic β-Cells In Vivo

The Second Activating Glucokinase Mutation (A456V): Implications for Glucose Homeostasis and Diabetes Therapy

Wortmannin Inhibits Insulin Secretion in Pancreatic Islets and β-TC3 Cells Independent of Its Inhibition of Phosphatidylinositol 3-Kinase

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