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Meeting Abstracts

721-P: Mechanisms of Relapse after Lifestyle Intervention–Induced Remission of Prediabetes

ARVID SANDFORTH, LEONTINE SANDFORTH, SARAH KATZENSTEIN, JOCHEN SEISSLER, NIKOLAOS PERAKAKIS, ROBERT WAGNER, JÜRGEN MACHANN, FRITZ SCHICK, ANDREAS PETER, HUBERT PREISSL, JULIA SZENDROEDI, MICHELE SOLIMENA, MATTHIAS BLÜHER, ANNETTE SCHÜRMANN, STEFAN KABISCH, ANDREAS F. PFEIFFER, STEFAN R. BORNSTEIN, MICHAEL RODEN, NORBERT STEFAN, ANDREAS FRITSCHE, ANDREAS L. BIRKENFELD, REINER JUMPERTZ VON SCHWARTZENBERG, PLIS WORKING GROUP
Journal: Diabetes
Diabetes 2024;73(Supplement_1):721-P
https://doi.org/10.2337/db24-721-P
Published: 14 June 2024
View article titled, 721-P: Mechanisms of Relapse after Lifestyle Intervention–Induced Remission of Prediabetes
Meeting Abstracts

71-OR: Rates of Remission and Metabolic Responses in Data-Driven High-Risk Prediabetes Clusters

SARAH KATZENSTEIN, ARVID SANDFORTH, VITORIA MINELLI FAIAO, LEONTINE SANDFORTH, FRITZ SCHICK, JÜRGEN MACHANN, ANDREAS PETER, JOCHEN SEISSLER, NIKOLAOS PERAKAKIS, ANNETTE SCHÜRMANN, ANDREAS F. PFEIFFER, STEFAN KABISCH, MATTHIAS BLÜHER, JULIA SZENDROEDI, MICHELE SOLIMENA, STEFAN R. BORNSTEIN, ANDREAS FRITSCHE, ROBERT WAGNER, MICHAEL RODEN, NORBERT STEFAN, REINER JUMPERTZ VON SCHWARTZENBERG, ANDREAS L. BIRKENFELD
Journal: Diabetes
Diabetes 2024;73(Supplement_1):71-OR
https://doi.org/10.2337/db24-71-OR
Published: 14 June 2024
View article titled, 71-OR: Rates of Remission and Metabolic Responses in Data-Driven High-Risk Prediabetes Clusters
Meeting Abstracts

72-OR: Mechanisms of Prediabetes Remission in People with Weight Gain after Lifestyle Intervention

ARVID SANDFORTH, ELSA VAZQUEZ ARREOLA, ROBERT L. HANSON, LEONTINE SANDFORTH, SARAH KATZENSTEIN, JOCHEN SEISSLER, NIKOLAOS PERAKAKIS, ROBERT WAGNER, JÜRGEN MACHANN, FRITZ SCHICK, ANDREAS PETER, HUBERT PREISSL, JULIA SZENDROEDI, MICHELE SOLIMENA, MATTHIAS BLÜHER, ANNETTE SCHÜRMANN, STEFAN KABISCH, ANDREAS F. PFEIFFER, STEFAN R. BORNSTEIN, MICHAEL RODEN, NORBERT STEFAN, ANDREAS FRITSCHE, ANDREAS L. BIRKENFELD, REINER JUMPERTZ VON SCHWARTZENBERG, PLIS WORKING GROUP
Journal: Diabetes
Diabetes 2024;73(Supplement_1):72-OR
https://doi.org/10.2337/db24-72-OR
Published: 14 June 2024
View article titled, 72-OR: Mechanisms of Prediabetes Remission in People with Weight Gain after Lifestyle Intervention
Meeting Abstracts

96-OR: Liver Fibrosis Scores in Novel Subclusters of Patients at Risk for Type 2 Diabetes

VITORIA MINELLI FAIAO, ARVID SANDFORTH, SARAH KATZENSTEIN, ANDREAS FRITSCHE, LOUISE FRITSCHE, JÜRGEN MACHANN, FRITZ SCHICK, HANS-ULRICH HÄRING, ROBERT WAGNER, ANDREAS PETER, ANDREAS L. BIRKENFELD, NORBERT STEFAN, REINER JUMPERTZ VON SCHWARTZENBERG
Journal: Diabetes
Diabetes 2023;72(Supplement_1):96-OR
https://doi.org/10.2337/db23-96-OR
Published: 20 June 2023
View article titled, 96-OR: Liver Fibrosis Scores in Novel Subclusters of Patients at Risk for Type 2 Diabetes
Journal Articles

Lower Hepatic Fat Is Associated With Improved Insulin Secretion in a High-Risk Prediabetes Subphenotype During Lifestyle Intervention

Robert Wagner, Martin Heni, Konstantinos Kantartzis, Arvid Sandforth, Jürgen Machann, Fritz Schick, Andreas Peter, Louise Fritsche, Julia Szendrödi, Andreas F.H. Pfeiffer, Annette Schürmann, Matthias Blüher, Hans Hauner, Jochen Seissler, Stefan Bornstein, Michael Roden, Norbert Stefan, Andreas L. Birkenfeld, Morris F. White, Hans-Ulrich Häring, Andreas Fritsche
Journal: Diabetes
Diabetes 2023;72(3):362–366
https://doi.org/10.2337/db22-0441
Published: 16 December 2022
View article titled, Lower Hepatic Fat Is Associated With Improved Insulin Secretion in a High-Risk Prediabetes Subphenotype During Lifestyle Intervention
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Journal Articles

Different Effects of Lifestyle Intervention in High- and Low-Risk Prediabetes: Results of the Randomized Controlled Prediabetes Lifestyle Intervention Study (PLIS)

Andreas Fritsche, Robert Wagner, Martin Heni, Kostantinos Kantartzis, Jürgen Machann, Fritz Schick, Rainer Lehmann, Andreas Peter, Corinna Dannecker, Louise Fritsche, Vera Valenta, Renate Schick, Peter Paul Nawroth, Stefan Kopf, Andreas F.H. Pfeiffer, Stefan Kabisch, Ulrike Dambeck, Michael Stumvoll, Matthias Blüher, Andreas L. Birkenfeld, Peter Schwarz, Hans Hauner, Julia Clavel, Jochen Seißler, Andreas Lechner, Karsten Müssig, Katharina Weber, Michael Laxy, Stefan Bornstein, Annette Schürmann, Michael Roden, Martin Hrabe de Angelis, Norbert Stefan, Hans-Ulrich Häring
Journal: Diabetes
Diabetes 2021;70(12):2785–2795
https://doi.org/10.2337/db21-0526
Published: 16 September 2021
View article titled, Different Effects of Lifestyle Intervention in High- and Low-Risk Prediabetes: Results of the Randomized Controlled Prediabetes Lifestyle Intervention Study (PLIS)
Open the PDF for Different Effects of Lifestyle Intervention in High- and Low-Risk Prediabetes: Results of the Randomized Controlled Prediabetes Lifestyle Intervention Study (PLIS) in another window
Meeting Abstracts

1856-P: Hepatic Insulin Clearance Is Not Driven by Liver Fat but by Systemic Inflammation: A Mendelian Randomization Study

APOSTOLIA LAMPRINOU, JÜRGEN MACHANN, FRITZ SCHICK, SABINE S. ECKSTEIN, CHIARA DALLA MAN, ROBERTO VISENTIN, NORBERT STEFAN, ANDREAS L. BIRKENFELD, ANDREAS PETER, HANS-ULRICH HAERING, ANDREAS FRITSCHE, MARTIN HENI, ROBERT WAGNER
Journal: Diabetes
Diabetes 2020;69(Supplement_1):1856-P
https://doi.org/10.2337/db20-1856-P
Published: 01 June 2020
View article titled, 1856-P: Hepatic Insulin Clearance Is Not Driven by Liver Fat but by Systemic Inflammation: A Mendelian Randomization Study
Meeting Abstracts

102-OR: Detection of Diabetes from Whole-Body Magnetic Resonance Imaging Using Deep Learning

ROBERT WAGNER, BENEDIKT DIETZ, JÜRGEN MACHANN, PATRICK SCHWAB, JULIA K. DIENES, STEFFEN REICHERT, ANDREAS L. BIRKENFELD, HANS-ULRICH HAERING, FRITZ SCHICK, NORBERT STEFAN, MARTIN HENI, HUBERT PREISSL, BERNHARD SCHÖLKOPF, STEFAN BAUER, ANDREAS FRITSCHE
Journal: Diabetes
Diabetes 2020;69(Supplement_1):102-OR
https://doi.org/10.2337/db20-102-OR
Published: 01 June 2020
View article titled, 102-OR: Detection of Diabetes from Whole-Body Magnetic Resonance Imaging Using Deep Learning
Meeting Abstracts

1834-P: Pancreatic Fat Associates with Impaired Insulin Secretion in Genetically Predisposed Individuals

BENJAMIN JAGHUTRIZ, MARTIN HENI, JÜRGEN MACHANN, FRITZ SCHICK, SUSANNE ULLRICH, HANS-ULRICH HAERING, ANDREAS FRITSCHE, ROBERT WAGNER
Journal: Diabetes
Diabetes 2019;68(Supplement_1):1834-P
https://doi.org/10.2337/db19-1834-P
Published: 01 June 2019
View article titled, 1834-P: Pancreatic Fat Associates with Impaired Insulin Secretion in Genetically Predisposed Individuals
Journal Articles

Nonsuppressed Glucagon After Glucose Challenge as a Potential Predictor for Glucose Tolerance

Róbert Wagner, Liisa H. Hakaste, Emma Ahlqvist, Martin Heni, Jürgen Machann, Fritz Schick, Emmanuel Van Obberghen, Norbert Stefan, Baptist Gallwitz, Tiinamaija Tuomi, Hans-Ulrich Häring, Leif Groop, Andreas Fritsche
Journal: Diabetes
Diabetes 2017;66(5):1373–1379
https://doi.org/10.2337/db16-0354
Published: 16 December 2016
View article titled, Nonsuppressed Glucagon After Glucose Challenge as a Potential Predictor for Glucose Tolerance
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Includes: Supplementary data
Journal Articles

TGF-β Contributes to Impaired Exercise Response by Suppression of Mitochondrial Key Regulators in Skeletal Muscle

Anja Böhm, Christoph Hoffmann, Martin Irmler, Patrick Schneeweiss, Günter Schnauder, Corinna Sailer, Vera Schmid, Jens Hudemann, Jürgen Machann, Fritz Schick, Johannes Beckers, Martin Hrabě de Angelis, Harald Staiger, Andreas Fritsche, Norbert Stefan, Andreas M. Nieß, Hans-Ulrich Häring, Cora Weigert
Journal: Diabetes
Diabetes 2016;65(10):2849–2861
https://doi.org/10.2337/db15-1723
Published: 29 June 2016
View article titled, TGF-β Contributes to Impaired Exercise Response by Suppression of Mitochondrial Key Regulators in Skeletal Muscle
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Includes: Supplementary data
Journal Articles

Monounsaturated Fatty Acids Prevent the Aversive Effects of Obesity on Locomotion, Brain Activity, and Sleep Behavior

Tina Sartorius, Caroline Ketterer, Stephanie Kullmann, Michelle Balzer, Carola Rotermund, Sonja Binder, Manfred Hallschmid, Jürgen Machann, Fritz Schick, Veronika Somoza, Hubert Preissl, Andreas Fritsche, Hans-Ulrich Häring, Anita M. Hennige
Journal: Diabetes
Diabetes 2012;61(7):1669–1679
https://doi.org/10.2337/db11-1521
Published: 15 June 2012
View article titled, Monounsaturated Fatty Acids Prevent the Aversive Effects of Obesity on Locomotion, Brain Activity, and Sleep Behavior
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Includes: Supplementary data
Journal Articles

Relationships of Circulating Sex Hormone–Binding Globulin With Metabolic Traits in Humans

Andreas Peter, Konstantinos Kantartzis, Jürgen Machann, Fritz Schick, Harald Staiger, Fausto Machicao, Erwin Schleicher, Andreas Fritsche, Hans-Ulrich Häring, Norbert Stefan
Journal: Diabetes
Diabetes 2010;59(12):3167–3173
https://doi.org/10.2337/db10-0179
Published: 14 September 2010
View article titled, Relationships of Circulating Sex Hormone–Binding Globulin With Metabolic Traits in Humans
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Journal Articles

Gene Variants of TCF7L2 Influence Weight Loss and Body Composition During Lifestyle Intervention in a Population at Risk for Type 2 Diabetes

Axel Haupt, Claus Thamer, Martin Heni, Caroline Ketterer, Jürgen Machann, Fritz Schick, Fausto Machicao, Norbert Stefan, Claus D. Claussen, Hans-Ulrich Häring, Andreas Fritsche, Harald Staiger
Journal: Diabetes
Diabetes 2010;59(3):747–750
https://doi.org/10.2337/db09-1050
Published: 22 December 2009
View article titled, Gene Variants of <em>TCF7L2</em> Influence Weight Loss and Body Composition During Lifestyle Intervention in a Population at Risk for Type 2 Diabetes
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Includes: Supplementary data
Journal Articles

Dissociation Between Fatty Liver and Insulin Resistance in Humans Carrying a Variant of the Patatin-Like Phospholipase 3 Gene

Konstantinos Kantartzis, Andreas Peter, Fausto Machicao, Jürgen Machann, Silvia Wagner, Ingmar Königsrainer, Alfred Königsrainer, Fritz Schick, Andreas Fritsche, Hans-Ulrich Häring, Norbert Stefan
Journal: Diabetes
Diabetes 2009;58(11):2616–2623
https://doi.org/10.2337/db09-0279
Published: 03 August 2009
View article titled, Dissociation Between Fatty Liver and Insulin Resistance in Humans Carrying a Variant of the Patatin-Like Phospholipase 3 Gene
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Journal Articles

Individual Stearoyl-CoA Desaturase 1 Expression Modulates Endoplasmic Reticulum Stress and Inflammation in Human Myotubes and Is Associated With Skeletal Muscle Lipid Storage and Insulin Sensitivity In Vivo

Andreas Peter, Cora Weigert, Harald Staiger, Fausto Machicao, Fritz Schick, Jürgen Machann, Norbert Stefan, Claus Thamer, Hans-Ulrich Häring, Erwin Schleicher
Journal: Diabetes
Diabetes 2009;58(8):1757–1765
https://doi.org/10.2337/db09-0188
Published: 28 May 2009
View article titled, Individual Stearoyl-CoA Desaturase 1 Expression Modulates Endoplasmic Reticulum Stress and Inflammation in Human Myotubes and Is Associated With Skeletal Muscle Lipid Storage and Insulin Sensitivity In Vivo
Open the PDF for Individual Stearoyl-CoA Desaturase 1 Expression Modulates Endoplasmic Reticulum Stress and Inflammation in Human Myotubes and Is Associated With Skeletal Muscle Lipid Storage and Insulin Sensitivity In Vivo in another window
Journal Articles

Muscle-Derived Angiopoietin-Like Protein 4 Is Induced by Fatty Acids via Peroxisome Proliferator–Activated Receptor (PPAR)-δ and Is of Metabolic Relevance in Humans

Harald Staiger, Carina Haas, Jürgen Machann, Roman Werner, Melanie Weisser, Fritz Schick, Fausto Machicao, Norbert Stefan, Andreas Fritsche, Hans-Ulrich Häring
Journal: Diabetes
Diabetes 2009;58(3):579–589
https://doi.org/10.2337/db07-1438
Published: 01 March 2009
View article titled, Muscle-Derived Angiopoietin-Like Protein 4 Is Induced by Fatty Acids via Peroxisome Proliferator–Activated Receptor (PPAR)-δ and Is of Metabolic Relevance in Humans
Open the PDF for Muscle-Derived Angiopoietin-Like Protein 4 Is Induced by Fatty Acids via Peroxisome Proliferator–Activated Receptor (PPAR)-δ and Is of Metabolic Relevance in Humans in another window
Includes: Supplementary data
Journal Articles

Effects of Intravenous and Dietary Lipid Challenge on Intramyocellular Lipid Content and the Relation With Insulin Sensitivity in Humans

Oliver P. Bachmann, Dominik B. Dahl, Klaus Brechtel, Jürgen Machann, Michael Haap, Thomas Maier, Mattias Loviscach, Michael Stumvoll, Claus D. Claussen, Fritz Schick, Hans U. Häring, Stephan Jacob
Journal: Diabetes
Diabetes 2001;50(11):2579–2584
https://doi.org/10.2337/diabetes.50.11.2579
Published: 01 November 2001
View article titled, Effects of Intravenous and Dietary Lipid Challenge on Intramyocellular Lipid Content and the Relation With Insulin Sensitivity in Humans
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