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Journal Articles

Babies of South Asian and European Ancestry Show Similar Associations With Genetic Risk Score for Birth Weight Despite the Smaller Size of South Asian Newborns

Diabetes 2022;71(4):821–836

Published: 21 January 2022

View article titled, Babies of South Asian and European Ancestry Show Similar Associations With Genetic Risk Score for Birth Weight Despite the Smaller Size of South Asian Newborns

Journal Articles

Adiposity-Related Heterogeneity in Patterns of Type 2 Diabetes Susceptibility Observed in Genome-Wide Association Data

Nicholas J. Timpson, Cecilia M. Lindgren, Michael N. Weedon, Joshua Randall, Willem H. Ouwehand, David P. Strachan, N. William Rayner, Mark Walker, Graham A. Hitman, Alex S.F. Doney, Colin N.A. Palmer, Andrew D. Morris, Andrew T. Hattersley, Eleftheria Zeggini, Timothy M. Frayling, Mark I. McCarthy

Diabetes 2009;58(2):505–510

https://doi.org/10.2337/db08-0906

Published: 01 February 2009

View article titled, Adiposity-Related Heterogeneity in Patterns of Type 2 Diabetes Susceptibility Observed in Genome-Wide Association Data

Includes: Supplementary data

Journal Articles

Common Variation in the LMNA Gene (Encoding Lamin A/C) and Type 2 Diabetes: Association Analyses in 9,518 Subjects

Katharine R. Owen, Christopher J. Groves, Robert L. Hanson, William C. Knowler, Alan R. Shuldiner, Steven C. Elbein, Braxton D. Mitchell, Philippe Froguel, Maggie C.Y. Ng, Juliana C. Chan, Weiping Jia, Panos Deloukas, Graham A. Hitman, Mark Walker, Timothy M. Frayling, Andrew T. Hattersley, Eleftheria Zeggini, Mark I. McCarthy, for the International Type 2 Diabetes 1q Consortium

Diabetes 2007;56(3):879–883

https://doi.org/10.2337/db06-0930

Published: 01 March 2007

View article titled, Common Variation in the LMNA Gene (Encoding Lamin A/C) and Type 2 Diabetes: <subtitle>Association Analyses in 9,518 Subjects</subtitle>

Includes: Supplementary data

Journal Articles

Variation Within the Gene Encoding the Upstream Stimulatory Factor 1 Does Not Influence Susceptibility to Type 2 Diabetes in Samples From Populations With Replicated Evidence of Linkage to Chromosome 1q

Diabetes 2006;55(9):2541–2548

https://doi.org/10.2337/db06-0088

Published: 01 September 2006

View article titled, Variation Within the Gene Encoding the Upstream Stimulatory Factor 1 Does Not Influence Susceptibility to Type 2 Diabetes in Samples From Populations With Replicated Evidence of Linkage to Chromosome 1q

Includes: Supplementary data

Journal Articles

Association Analysis of 6,736 U.K. Subjects Provides Replication and Confirms TCF7L2 as a Type 2 Diabetes Susceptibility Gene With a Substantial Effect on Individual Risk

Christopher J. Groves, Eleftheria Zeggini, Jayne Minton, Timothy M. Frayling, Michael N. Weedon, Nigel W. Rayner, Graham A. Hitman, Mark Walker, Steven Wiltshire, Andrew T. Hattersley, Mark I. McCarthy

Diabetes 2006;55(9):2640–2644

https://doi.org/10.2337/db06-0355

Published: 01 September 2006

View article titled, Association Analysis of 6,736 U.K. Subjects Provides Replication and Confirms TCF7L2 as a Type 2 Diabetes Susceptibility Gene With a Substantial Effect on Individual Risk

Includes: Supplementary data

Journal Articles

Significant Linkage of BMI to Chromosome 10p in the U.K. Population and Evaluation of GAD2 as a Positional Candidate

Christopher J. Groves, Eleftheria Zeggini, Mark Walker, Graham A. Hitman, Jonathan C. Levy, Stephen O’Rahilly, Andrew T. Hattersley, Mark I. McCarthy, Steven Wiltshire

Diabetes 2006;55(6):1884–1889

https://doi.org/10.2337/db05-1674

Published: 01 June 2006

View article titled, Significant Linkage of BMI to Chromosome 10p in the U.K. Population and Evaluation of GAD2 as a Positional Candidate

Journal Articles

The Variable Number of Tandem Repeats Upstream of the Insulin Gene Is a Susceptibility Locus for Latent Autoimmune Diabetes in Adults

Minal Desai, Eleftheria Zeggini, Virginia A. Horton, Katharine R. Owen, Andrew T. Hattersley, Jonathan C. Levy, Graham A. Hitman, Mark Walker, Rury R. Holman, Mark I. McCarthy, Anne Clark

Diabetes 2006;55(6):1890–1894

https://doi.org/10.2337/db06-0089

Published: 01 June 2006

View article titled, The Variable Number of Tandem Repeats Upstream of the Insulin Gene Is a Susceptibility Locus for Latent Autoimmune Diabetes in Adults

Journal Articles

Association Studies of Insulin Receptor Substrate 1 Gene (IRS1) Variants in Type 2 Diabetes Samples Enriched for Family History and Early Age of Onset

Eleftheria Zeggini, James Parkinson, Stephanie Halford, Katharine R. Owen, Timothy M. Frayling, Mark Walker, Graham A. Hitman, Jonathan C. Levy, Mike J. Sampson, Edith J.M. Feskens, Andrew T. Hattersley, Mark I. McCarthy

Diabetes 2004;53(12):3319–3322

https://doi.org/10.2337/diabetes.53.12.3319

Published: 01 December 2004

View article titled, Association Studies of Insulin Receptor Substrate 1 Gene (IRS1) Variants in Type 2 Diabetes Samples Enriched for Family History and Early Age of Onset

Journal Articles

Polymorphic Variations in the Neurogenic Differentiation-1, Neurogenin-3, and Hepatocyte Nuclear Factor-1α Genes Contribute to Glucose Intolerance in a South Indian Population

Alan E. Jackson, Paul G. Cassell, Bernard V. North, Shanti Vijayaraghavan, Susan V. Gelding, Ambady Ramachandran, Chamukuttan Snehalatha, Graham A. Hitman

Diabetes 2004;53(8):2122–2125

https://doi.org/10.2337/diabetes.53.8.2122

Published: 01 August 2004

View article titled, Polymorphic Variations in the Neurogenic Differentiation-1, Neurogenin-3, and Hepatocyte Nuclear Factor-1α Genes Contribute to Glucose Intolerance in a South Indian Population

Journal Articles

Evidence From a Large U.K. Family Collection That Genes Influencing Age of Onset of Type 2 Diabetes Map to Chromosome 12p and to the MODY3/NIDDM2 Locus on 12q24

Steven Wiltshire, Timothy M. Frayling, Christopher J. Groves, Jonathan C. Levy, Graham A. Hitman, Mike Sampson, Mark Walker, Stephan Menzel, Andrew T. Hattersley, Lon R. Cardon, Mark I. McCarthy

Diabetes 2004;53(3):855–860

https://doi.org/10.2337/diabetes.53.3.855

Published: 01 March 2004

View article titled, Evidence From a Large U.K. Family Collection That Genes Influencing Age of Onset of Type 2 Diabetes Map to Chromosome 12p and to the MODY3/NIDDM2 Locus on 12q24

Journal Articles

Young-Onset Type 2 Diabetes Families Are the Major Contributors to Genetic Loci in the Diabetes UK Warren 2 Genome Scan and Identify Putative Novel Loci on Chromosomes 8q21, 21q22, and 22q11

Timothy M. Frayling, Steven Wiltshire, Graham A. Hitman, Mark Walker, Jonathan C. Levy, Mike Sampson, Christopher J. Groves, Stephan Menzel, Mark I. McCarthy, Andrew T. Hattersley

Diabetes 2003;52(7):1857–1863

https://doi.org/10.2337/diabetes.52.7.1857

Published: 01 July 2003

View article titled, Young-Onset Type 2 Diabetes Families Are the Major Contributors to Genetic Loci in the Diabetes UK Warren 2 Genome Scan and Identify Putative Novel Loci on Chromosomes 8q21, 21q22, and 22q11

Journal Articles

Fetal Programming of Perivenous Glucose Uptake Reveals a Regulatory Mechanism Governing Hepatic Glucose Output During Refeeding

Helena C. Murphy, Gemma Regan, Irina G. Bogdarina, Adrian J.L. Clark, Richard A. Iles, Robert D. Cohen, Graham A. Hitman, Colin L. Berry, Zoe Coade, Clive J. Petry, Shamus P. Burns

Diabetes 2003;52(6):1326–1332

https://doi.org/10.2337/diabetes.52.6.1326

Published: 01 June 2003

View article titled, Fetal Programming of Perivenous Glucose Uptake Reveals a Regulatory Mechanism Governing Hepatic Glucose Output During Refeeding

Journal Articles

Association and Haplotype Analysis of the Insulin-Degrading Enzyme (IDE) Gene, a Strong Positional and Biological Candidate for Type 2 Diabetes Susceptibility

Christopher J. Groves, Steven Wiltshire, Damian Smedley, Katherine R. Owen, Timothy M. Frayling, Mark Walker, Graham A. Hitman, Jonathan C. Levy, Stephen O’Rahilly, Stephan Menzel, Andrew T. Hattersley, Mark I. McCarthy

Diabetes 2003;52(5):1300–1305

https://doi.org/10.2337/diabetes.52.5.1300

Published: 01 May 2003

View article titled, Association and Haplotype Analysis of the Insulin-Degrading Enzyme (IDE) Gene, a Strong Positional and Biological Candidate for Type 2 Diabetes Susceptibility

Includes: Supplementary data

Journal Articles

Vitamin D Receptor (VDR) mRNA and VDR Protein Levels in Relation to Vitamin D Status, Insulin Secretory Capacity, and VDR Genotype in Bangladeshi Asians

Babatunji-William Ogunkolade, Barbara J. Boucher, Jean M. Prahl, Stephen A. Bustin, Jacky M. Burrin, Kate Noonan, Bernard V. North, Nassima Mannan, Michael F. McDermott, Hector F. DeLuca, Graham A. Hitman

Diabetes 2002;51(7):2294–2300

https://doi.org/10.2337/diabetes.51.7.2294

Published: 01 July 2002

View article titled, Vitamin D Receptor (VDR) mRNA and VDR Protein Levels in Relation to Vitamin D Status, Insulin Secretory Capacity, and VDR Genotype in Bangladeshi Asians

Journal Articles

Haplotype Combinations of Calpain 10 Gene Polymorphisms Associate With Increased Risk of Impaired Glucose Tolerance and Type 2 Diabetes in South Indians

Paul G. Cassell, Alan E. Jackson, Bernard V. North, Julie C. Evans, Denise Syndercombe-Court, Chris Phillips, Ambady Ramachandran, Chamukuttan Snehalatha, Susan V. Gelding, Shanti Vijayaravaghan, David Curtis, Graham A. Hitman

Diabetes 2002;51(5):1622–1628

https://doi.org/10.2337/diabetes.51.5.1622

Published: 01 May 2002

View article titled, Haplotype Combinations of Calpain 10 Gene Polymorphisms Associate With Increased Risk of Impaired Glucose Tolerance and Type 2 Diabetes in South Indians

Includes: Supplementary data

NARROW

Babies of South Asian and European Ancestry Show Similar Associations With Genetic Risk Score for Birth Weight Despite the Smaller Size of South Asian Newborns

Adiposity-Related Heterogeneity in Patterns of Type 2 Diabetes Susceptibility Observed in Genome-Wide Association Data

Common Variation in the LMNA Gene (Encoding Lamin A/C) and Type 2 Diabetes: Association Analyses in 9,518 Subjects

Variation Within the Gene Encoding the Upstream Stimulatory Factor 1 Does Not Influence Susceptibility to Type 2 Diabetes in Samples From Populations With Replicated Evidence of Linkage to Chromosome 1q

Association Analysis of 6,736 U.K. Subjects Provides Replication and Confirms TCF7L2 as a Type 2 Diabetes Susceptibility Gene With a Substantial Effect on Individual Risk

Significant Linkage of BMI to Chromosome 10p in the U.K. Population and Evaluation of GAD2 as a Positional Candidate

The Variable Number of Tandem Repeats Upstream of the Insulin Gene Is a Susceptibility Locus for Latent Autoimmune Diabetes in Adults

Association Studies of Insulin Receptor Substrate 1 Gene (IRS1) Variants in Type 2 Diabetes Samples Enriched for Family History and Early Age of Onset

Polymorphic Variations in the Neurogenic Differentiation-1, Neurogenin-3, and Hepatocyte Nuclear Factor-1α Genes Contribute to Glucose Intolerance in a South Indian Population

Evidence From a Large U.K. Family Collection That Genes Influencing Age of Onset of Type 2 Diabetes Map to Chromosome 12p and to the MODY3/NIDDM2 Locus on 12q24

Young-Onset Type 2 Diabetes Families Are the Major Contributors to Genetic Loci in the Diabetes UK Warren 2 Genome Scan and Identify Putative Novel Loci on Chromosomes 8q21, 21q22, and 22q11

Fetal Programming of Perivenous Glucose Uptake Reveals a Regulatory Mechanism Governing Hepatic Glucose Output During Refeeding

Association and Haplotype Analysis of the Insulin-Degrading Enzyme (IDE) Gene, a Strong Positional and Biological Candidate for Type 2 Diabetes Susceptibility

Vitamin D Receptor (VDR) mRNA and VDR Protein Levels in Relation to Vitamin D Status, Insulin Secretory Capacity, and VDR Genotype in Bangladeshi Asians

Haplotype Combinations of Calpain 10 Gene Polymorphisms Associate With Increased Risk of Impaired Glucose Tolerance and Type 2 Diabetes in South Indians

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