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Graham Hitman
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Journal Articles

Total Soluble and Endogenous Secretory Receptor for Advanced Glycation End Products as Predictive Biomarkers of Coronary Heart Disease Risk in Patients With Type 2 Diabetes: An Analysis From the CARDS Trial

Open Access
Helen M. Colhoun, D. John Betteridge, Paul Durrington, Graham Hitman, Andrew Neil, Shona Livingstone, Valentine Charlton-Menys, Weihang Bao, David A. DeMicco, Gregory M. Preston, Harshal Deshmukh, Kathryn Tan, John H. Fuller
Journal: Diabetes
Diabetes 2011;60(9):2379–2385
https://doi.org/10.2337/db11-0291
Published: 20 August 2011
View articletitled, Total Soluble and Endogenous Secretory Receptor for Advanced Glycation End Products as Predictive Biomarkers of Coronary Heart Disease Risk in Patients With Type 2 Diabetes: An Analysis From the CARDS Trial
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Journal Articles

Population-Specific Risk of Type 2 Diabetes Conferred by HNF4A P2 Promoter Variants: A Lesson for Replication Studies

Free
Inês Barroso, Jian’an Luan, Eleanor Wheeler, Pamela Whittaker, Jon Wasson, Eleftheria Zeggini, Michael N. Weedon, Sarah Hunt, Ranganath Venkatesh, Timothy M. Frayling, Marcos Delgado, Rosalind J. Neuman, Jinghua Zhao, Richard Sherva, Benjamin Glaser, Mark Walker, Graham Hitman, Mark I. McCarthy, Andrew T. Hattersley, M. Alan Permutt, Nicholas J. Wareham, Panagiotis Deloukas
Journal: Diabetes
Diabetes 2008;57(11):3161–3165
https://doi.org/10.2337/db08-0719
Published: 01 November 2008
View articletitled, Population-Specific Risk of Type 2 Diabetes Conferred by HNF4A P2 Promoter Variants: A Lesson for Replication Studies
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Includes: Supplementary data
Journal Articles

Evaluation of Common Variants in the Six Known Maturity-Onset Diabetes of the Young (MODY) Genes for Association With Type 2 Diabetes

Free
Wendy Winckler, Michael N. Weedon, Robert R. Graham, Steven A. McCarroll, Shaun Purcell, Peter Almgren, Tiinamaija Tuomi, Daniel Gaudet, Kristina Bengtsson Boström, Mark Walker, Graham Hitman, Andrew T. Hattersley, Mark I. McCarthy, Kristin G. Ardlie, Joel N. Hirschhorn, Mark J. Daly, Timothy M. Frayling, Leif Groop, David Altshuler
Journal: Diabetes
Diabetes 2007;56(3):685–693
https://doi.org/10.2337/db06-0202
Published: 01 March 2007
View articletitled, Evaluation of Common Variants in the Six Known Maturity-Onset Diabetes of the Young (MODY) Genes for Association With Type 2 Diabetes
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Includes: Supplementary data
Journal Articles

No Evidence of Association of ENPP1 Variants With Type 2 Diabetes or Obesity in a Study of 8,089 U.K. Caucasians

Free
Michael N. Weedon, Beverley Shields, Graham Hitman, Mark Walker, Mark I. McCarthy, Andrew T. Hattersley, Timothy M. Frayling
Journal: Diabetes
Diabetes 2006;55(11):3175–3179
https://doi.org/10.2337/db06-0410
Published: 01 November 2006
View articletitled, No Evidence of Association of ENPP1 Variants With Type 2 Diabetes or Obesity in a Study of 8,089 U.K. Caucasians
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Includes: Supplementary data
Journal Articles

Assessment of the Role of Common Genetic Variation in the Transient Neonatal Diabetes Mellitus (TNDM) Region in Type 2 Diabetes : A Comparative Genomic and Tagging Single Nucleotide Polymorphism Approach

Free
Anna L. Gloyn, Deborah J.G. Mackay, Michael N. Weedon, Mark I. McCarthy, Mark Walker, Graham Hitman, Bridget A. Knight, Katharine R. Owen, Andrew T. Hattersley, Timothy M. Frayling
Journal: Diabetes
Diabetes 2006;55(8):2272–2276
https://doi.org/10.2337/db06-0216
Published: 01 August 2006
View articletitled, Assessment of the Role of Common Genetic Variation in the Transient Neonatal Diabetes Mellitus (TNDM) Region in Type 2 Diabetes : A Comparative Genomic and Tagging Single Nucleotide Polymorphism Approach
Open the PDF for Assessment of the Role of Common Genetic Variation in the Transient Neonatal Diabetes Mellitus (TNDM) Region in Type 2 Diabetes : A Comparative Genomic and Tagging Single Nucleotide Polymorphism Approach in another window
Includes: Supplementary data
Journal Articles

A Large-Scale Association Analysis of Common Variation of the HNF1α Gene With Type 2 Diabetes in the U.K. Caucasian Population

Free
Michael N. Weedon, Katharine R. Owen, Beverley Shields, Graham Hitman, Mark Walker, Mark I. McCarthy, Andrew T. Hattersley, Timothy M. Frayling
Journal: Diabetes
Diabetes 2005;54(8):2487–2491
https://doi.org/10.2337/diabetes.54.8.2487
Published: 01 August 2005
View articletitled, A Large-Scale Association Analysis of Common Variation of the HNF1α Gene With Type 2 Diabetes in the U.K. Caucasian Population
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Includes: Supplementary data
Journal Articles

Common Variants of the Hepatocyte Nuclear Factor-4α P2 Promoter Are Associated With Type 2 Diabetes in the U.K. Population

Free
Michael N. Weedon, Katharine R. Owen, Beverley Shields, Graham Hitman, Mark Walker, Mark I. McCarthy, Latisha D. Love-Gregory, M. Alan Permutt, Andrew T. Hattersley, Timothy M. Frayling
Journal: Diabetes
Diabetes 2004;53(11):3002–3006
https://doi.org/10.2337/diabetes.53.11.3002
Published: 01 November 2004
View articletitled, Common Variants of the Hepatocyte Nuclear Factor-4α P2 Promoter Are Associated With Type 2 Diabetes in the U.K. Population
Open the PDF for Common Variants of the Hepatocyte Nuclear Factor-4α P2 Promoter Are Associated With Type 2 Diabetes in the U.K. Population in another window
Includes: Supplementary data
Journal Articles

Large-Scale Association Studies of Variants in Genes Encoding the Pancreatic β-Cell KATP Channel Subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) Confirm That the KCNJ11 E23K Variant Is Associated With Type 2 Diabetes

Free
Anna L. Gloyn, Michael N. Weedon, Katharine R. Owen, Martina J. Turner, Bridget A. Knight, Graham Hitman, Mark Walker, Jonathan C. Levy, Mike Sampson, Stephanie Halford, Mark I. McCarthy, Andrew T. Hattersley, Timothy M. Frayling
Journal: Diabetes
Diabetes 2003;52(2):568–572
https://doi.org/10.2337/diabetes.52.2.568
Published: 01 February 2003
View articletitled, Large-Scale Association Studies of Variants in Genes Encoding the Pancreatic β-Cell KATP Channel Subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) Confirm That the KCNJ11 E23K Variant Is Associated With Type 2 Diabetes
Open the PDF for Large-Scale Association Studies of Variants in Genes Encoding the Pancreatic β-Cell KATP Channel Subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) Confirm That the KCNJ11 E23K Variant Is Associated With Type 2 Diabetes in another window
Journal Articles

Chromosome 4q Locus Associated With Insulin Resistance in Pima Indians: Studies in Three European NIDDM Populations

Free
Phillippa Humphreys, Mark McCarthy, Jaakko Tuomilehto, Eva Tuomilehto-Wolf, Irene Stratton, Ruth Morgan, Alan Rees, David Owens, Jari Stengård, Aulikki Nissinen, Graham Hitman, Robert C Turner, Stephen O'Rahilly
Journal: Diabetes
Diabetes 1994;43(6):800–804
https://doi.org/10.2337/diab.43.6.800
Published: 01 June 1994
View articletitled, Chromosome 4q Locus Associated With Insulin Resistance in Pima Indians: Studies in Three European NIDDM Populations
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