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Meeting Abstracts

1532-P: Expression of Fibroblast Growth Factor-1 by Medial Hypothalamic Neurons Is Required for Normal Glucose and Energy Homeostasis

PIQUE CHOI, CAELEY BRYAN, GREGORY J. MORTON, MICHAEL W. SCHWARTZ, JARRAD M. SCARLETT

Diabetes 2024;73(Supplement_1):1532-P

https://doi.org/10.2337/db24-1532-P

Published: 14 June 2024

View article titled, 1532-P: Expression of Fibroblast Growth Factor-1 by Medial Hypothalamic Neurons Is Required for Normal Glucose and Energy Homeostasis

Meeting Abstracts

1531-P: Identification of a Novel Subset of Cold-Activated Hypothalamic Neurons That Stimulate Feeding

CHRISTINA A. WATTS, JENNIFER D. DEEM, INGRID K. REDFORD, CAELEY BRYAN, BAO ANH N. PHAN, VINCENT DAMIAN, JARRAD M. SCARLETT, MICHAEL W. SCHWARTZ, GREGORY J. MORTON

Diabetes 2024;73(Supplement_1):1531-P

https://doi.org/10.2337/db24-1531-P

Published: 14 June 2024

View article titled, 1531-P: Identification of a Novel Subset of Cold-Activated Hypothalamic Neurons That Stimulate Feeding

Meeting Abstracts

1523-P: Anorexia Induced by the Central Action of Fibroblast Growth Factor 1 (FGF1) Is Dependent on Activation of Parabrachial CGRP Neurons

JARRAD M. SCARLETT, CAELEY BRYAN, INGRID K. REDFORD, KIMBERLY M. ALONGE, GREGORY J. MORTON, MICHAEL W. SCHWARTZ

Diabetes 2024;73(Supplement_1):1523-P

https://doi.org/10.2337/db24-1523-P

Published: 14 June 2024

View article titled, 1523-P: Anorexia Induced by the Central Action of Fibroblast Growth Factor 1 (FGF1) Is Dependent on Activation of Parabrachial CGRP Neurons

Journal Articles

Identification of Hypothalamic Glucoregulatory Neurons That Sense and Respond to Changes in Glycemia

Jennifer D. Deem, David Tingley, Anne-Mette Bjerregaard, Anna Secher, Owen Chan, Chukwuemeka Uzo, Nicole E. Richardson, Elizabeth Giering, Tammy Doan, Bao A. Phan, Brandon Wu, Jarrad M. Scarlett, Gregory J. Morton, Michael W. Schwartz

Diabetes 2023;72(9):1207–1213

https://doi.org/10.2337/db23-0139

Published: 22 June 2023

View article titled, Identification of Hypothalamic Glucoregulatory Neurons That Sense and Respond to Changes in Glycemia

Meeting Abstracts

1527-P: Anorexia Induced by the Central Action of Fibroblast Growth Factor 1 (FGF1) Is Dependent on Reduced GABA Receptor Activation

JARRAD M. SCARLETT, KIMBERLY M. ALONGE, BAO ANH N. PHAN, GREGORY J. MORTON, MICHAEL W. SCHWARTZ

Diabetes 2023;72(Supplement_1):1527-P

https://doi.org/10.2337/db23-1527-P

Published: 20 June 2023

View article titled, 1527-P: Anorexia Induced by the Central Action of Fibroblast Growth Factor 1 (FGF1) Is Dependent on Reduced GABA Receptor Activation

Meeting Abstracts

157-OR: High-Fat–Diet Feeding Disrupts Thermal Responsiveness of AgRP Neurons

JENNIFER D. DEEM, TAMMY P. DOAN, BAO ANH N. PHAN, KAYOKO OGIMOTO, SHANNON J.W. HU, BRANDON WU, MICHAEL W. SCHWARTZ, GREGORY J. MORTON

Diabetes 2022;71(Supplement_1):157-OR

https://doi.org/10.2337/db22-157-OR

Published: 01 June 2022

View article titled, 157-OR: High-Fat–Diet Feeding Disrupts Thermal Responsiveness of AgRP Neurons

Meeting Abstracts

152-OR: Evidence Linking Loss of Hypothalamic Perineuronal Nets to Obesity Pathogenesis

KIMBERLY M. ALONGE, MAURICIO D. DORFMAN, JARRAD M. SCARLETT, SUSAN J. MELHORN, YUANCHAO YE, SHANNON J.W. HU, KENDRA L. FRANCIS, AARUN HENDRICKSON, KATHERINE CUI, GREGORY J. MORTON, ELLEN SCHUR, JOSHUA THALER, MICHAEL W. SCHWARTZ

Diabetes 2022;71(Supplement_1):152-OR

https://doi.org/10.2337/db22-152-OR

Published: 01 June 2022

View article titled, 152-OR: Evidence Linking Loss of Hypothalamic Perineuronal Nets to Obesity Pathogenesis

Meeting Abstracts

209-LB: Evidence Thathypothalamic Glucoregulatory Neurons Sense and Respond to Changes of Glycemia in Conscious, Free-Living Mice

JENNIFER D. DEEM, DAVID TINGLEY, ANNE-METTE BJERREGAARD, CHELSEA L. FABER, TAMMY P. DOAN, BAO ANH N. PHAN, ZAINAB NASIR, BRANDON WU, MATTHEW K. HWANG, ASMIT KUMAR, JARRAD M. SCARLETT, GREGORY J. MORTON, MICHAEL W. SCHWARTZ

Diabetes 2022;71(Supplement_1):209-LB

https://doi.org/10.2337/db22-209-LB

Published: 01 June 2022

View article titled, 209-LB: Evidence Thathypothalamic Glucoregulatory Neurons Sense and Respond to Changes of Glycemia in Conscious, Free-Living Mice

Journal Articles

Erratum. The Hypothalamic Arcuate Nucleus–Median Eminence Is a Target for Sustained Diabetes Remission Induced by Fibroblast Growth Factor 1. Diabetes 2019;68: 1054–1061

Jenny M. Brown, Jarrad M. Scarlett, Miles E. Matsen, Hong T. Nguyen, Anna Secher, Rasmus Jorgensen, Gregory J. Morton, Michael W. Schwartz

Diabetes 2021;70(3):817

https://doi.org/10.2337/db21-er03a

Published: 18 December 2020

View article titled, Erratum. The Hypothalamic Arcuate Nucleus–Median Eminence Is a Target for Sustained Diabetes Remission Induced by Fibroblast Growth Factor 1. Diabetes 2019;68: 1054–1061

Meeting Abstracts

209-OR: Evidence that Agrp Neuron Activation Drives Cold-Induced Hyperphagia

JENNIFER D. DEEM, CHELSEA L. FABER, CHRISTIAN PEDERSEN, BAO ANH N. PHAN, KAYOKO OGIMOTO, SARAH A. LARSEN, MEGAN A. TRAN, VINCENT DAMIAN, KARL KAIYALA, JARRAD SCARLETT, MICHAEL R. BRUCHAS, MICHAEL W. SCHWARTZ, GREGORY J. MORTON

Diabetes 2020;69(Supplement_1):209-OR

https://doi.org/10.2337/db20-209-OR

Published: 01 June 2020

View article titled, 209-OR: Evidence that Agrp Neuron Activation Drives Cold-Induced Hyperphagia

Meeting Abstracts

1771-P: Hypothalamic Perineuronal Net Assembly Is Required for Sustained Diabetes Remission Induced by FGF1

KIMBERLY M. ALONGE, ZAMAN MIRZADEH, JARRAD SCARLETT, ARIC LOGSDON, JENNY M. BROWN, ELAINE CABRALES, CHRISTINA K. CHAN, KARL KAIYALA, MARIE A. BENTSEN, WILLIAM A. BANKS, MIKLOS GUTTMAN, THOMAS N. WIGHT, GREGORY J. MORTON, MICHAEL W. SCHWARTZ

Diabetes 2020;69(Supplement_1):1771-P

https://doi.org/10.2337/db20-1771-P

Published: 01 June 2020

View article titled, 1771-P: Hypothalamic Perineuronal Net Assembly Is Required for Sustained Diabetes Remission Induced by FGF1

Meeting Abstracts

214-OR: Role of Hypothalamic MAPK/ERK Signaling in Diabetes Remission Induced by the Central Action of Fibroblast Growth Factor 1 (FGF1)

JENNY M. BROWN, BAO ANH N. PHAN, HUZAIFA WASANWALA, MILES E. MATSEN, ANNA SECHER, GREGORY J. MORTON, MICHAEL W. SCHWARTZ, JARRAD SCARLETT

Diabetes 2020;69(Supplement_1):214-OR

https://doi.org/10.2337/db20-214-OR

Published: 01 June 2020

View article titled, 214-OR: Role of Hypothalamic MAPK/ERK Signaling in Diabetes Remission Induced by the Central Action of Fibroblast Growth Factor 1 (FGF1)

Meeting Abstracts

101-OR: Identification of Warm Sensitive Neurons in the Hypothalamic Preoptic Area as Powerful Regulators of Glucose Homeostasis

JENNIFER D. DEEM, KAYOKO OGIMOTO, JARRELL NELSON, BAO ANH N. PHAN, KEVIN R. VELASCO, VINCENT DAMIAN, ZACHARY KNIGHT, MICHAEL W. SCHWARTZ, GREGORY J. MORTON

Diabetes 2019;68(Supplement_1):101-OR

https://doi.org/10.2337/db19-101-OR

Published: 01 June 2019

View article titled, 101-OR: Identification of Warm Sensitive Neurons in the Hypothalamic Preoptic Area as Powerful Regulators of Glucose Homeostasis

Meeting Abstracts

98-OR: Cold-Induced Hyperphagia Requires AgRP Neuron Activation

JENNIFER D. DEEM, KAYOKO OGIMOTO, JARRELL NELSON, BAO ANH N. PHAN, KEVIN R. VELASCO, VINCENT DAMIAN, MICHAEL W. SCHWARTZ, GREGORY J. MORTON

Diabetes 2019;68(Supplement_1):98-OR

https://doi.org/10.2337/db19-98-OR

Published: 01 June 2019

View article titled, 98-OR: Cold-Induced Hyperphagia Requires AgRP Neuron Activation

Meeting Abstracts

1824-P: Leptin Receptor Neurons in the Hypothalamic Ventromedial Nucleus Play a Physiological Role in Regulating Glucose Tolerance

CHELSEA L. FABER, TRISTA J. HARVEY, KEVIN R. VELASCO, VINCENT DAMIAN, MICHAEL W. SCHWARTZ, GREGORY J. MORTON

Diabetes 2019;68(Supplement_1):1824-P

https://doi.org/10.2337/db19-1824-P

Published: 01 June 2019

View article titled, 1824-P: Leptin Receptor Neurons in the Hypothalamic Ventromedial Nucleus Play a Physiological Role in Regulating Glucose Tolerance

Journal Articles

The Hypothalamic Arcuate Nucleus–Median Eminence Is a Target for Sustained Diabetes Remission Induced by Fibroblast Growth Factor 1

Jenny M. Brown, Jarrad M. Scarlett, Miles E. Matsen, Hong T. Nguyen, Anna Secher, Rasmus Jorgensen, Gregory J. Morton, Michael W. Schwartz

Diabetes 2019;68(5):1054–1061

https://doi.org/10.2337/db19-0025

Published: 22 February 2019

View article titled, The Hypothalamic Arcuate Nucleus–Median Eminence Is a Target for Sustained Diabetes Remission Induced by Fibroblast Growth Factor 1

Journal Articles

Peripheral Mechanisms Mediating the Sustained Antidiabetic Action of FGF1 in the Brain

Jarrad M. Scarlett, Kenjiro Muta, Jenny M. Brown, Jennifer M. Rojas, Miles E. Matsen, Nikhil K. Acharya, Anna Secher, Camilla Ingvorsen, Rasmus Jorgensen, Thomas Høeg-Jensen, Darko Stefanovski, Richard N. Bergman, Francesca Piccinini, Karl J. Kaiyala, Masakazu Shiota, Gregory J. Morton, Michael W. Schwartz

Diabetes 2019;68(3):654–664

https://doi.org/10.2337/db18-0498

Published: 06 December 2018

View article titled, Peripheral Mechanisms Mediating the Sustained Antidiabetic Action of FGF1 in the Brain

Includes: Supplementary data

Journal Articles

Distinct Neuronal Projections From the Hypothalamic Ventromedial Nucleus Mediate Glycemic and Behavioral Effects

Chelsea L. Faber, Miles E. Matsen, Kevin R. Velasco, Vincent Damian, Bao Anh Phan, Daniel Adam, Anthony Therattil, Michael W. Schwartz, Gregory J. Morton

Diabetes 2018;67(12):2518–2529

https://doi.org/10.2337/db18-0380

Published: 26 September 2018

View article titled, Distinct Neuronal Projections From the Hypothalamic Ventromedial Nucleus Mediate Glycemic and Behavioral Effects

Meeting Abstracts

An Action in the Hypothalamic Arcuate Nucleus Is Sufficient to Explain the Sustained Remission of Diabetes Induced by Central Administration of Fibroblast Growth Factor-1 (FGF-1)

JENNY M. BROWN, JARRAD SCARLETT, MILES E. MATSEN, ANNA SECHER, RASMUS JORGENSEN, GREGORY J. MORTON, MICHAEL W. SCHWARTZ

Diabetes 2018;67(Supplement_1):372-OR

https://doi.org/10.2337/db18-372-OR

Published: 01 July 2018

View article titled, An Action in the Hypothalamic Arcuate Nucleus Is Sufficient to Explain the Sustained Remission of Diabetes Induced by Central Administration of Fibroblast Growth Factor-1 (FGF-1)

Meeting Abstracts

Sustained Diabetes Remission Induced by the Central Action of Fibroblast Growth Factor-1 (FGF-1) Requires Activation of Integrin Receptor aνß3

JARRAD SCARLETT, JENNY M. BROWN, BAO ANH N. PHAN, EDDIE L. KHAV, MILES E. MATSEN, NIKHIL K. ACHARYA, HONG T. NGUYEN, ANNA SECHER, RASMUS JORGENSEN, GREGORY J. MORTON, MICHAEL W. SCHWARTZ

Diabetes 2018;67(Supplement_1):373-OR

https://doi.org/10.2337/db18-373-OR

Published: 01 July 2018

View article titled, Sustained Diabetes Remission Induced by the Central Action of Fibroblast Growth Factor-1 (FGF-1) Requires Activation of Integrin Receptor aνß3

NARROW

1532-P: Expression of Fibroblast Growth Factor-1 by Medial Hypothalamic Neurons Is Required for Normal Glucose and Energy Homeostasis

1531-P: Identification of a Novel Subset of Cold-Activated Hypothalamic Neurons That Stimulate Feeding

1523-P: Anorexia Induced by the Central Action of Fibroblast Growth Factor 1 (FGF1) Is Dependent on Activation of Parabrachial CGRP Neurons

Identification of Hypothalamic Glucoregulatory Neurons That Sense and Respond to Changes in Glycemia

1527-P: Anorexia Induced by the Central Action of Fibroblast Growth Factor 1 (FGF1) Is Dependent on Reduced GABA Receptor Activation

157-OR: High-Fat–Diet Feeding Disrupts Thermal Responsiveness of AgRP Neurons

152-OR: Evidence Linking Loss of Hypothalamic Perineuronal Nets to Obesity Pathogenesis

209-LB: Evidence Thathypothalamic Glucoregulatory Neurons Sense and Respond to Changes of Glycemia in Conscious, Free-Living Mice

Erratum. The Hypothalamic Arcuate Nucleus–Median Eminence Is a Target for Sustained Diabetes Remission Induced by Fibroblast Growth Factor 1. Diabetes 2019;68: 1054–1061

209-OR: Evidence that Agrp Neuron Activation Drives Cold-Induced Hyperphagia

1771-P: Hypothalamic Perineuronal Net Assembly Is Required for Sustained Diabetes Remission Induced by FGF1

214-OR: Role of Hypothalamic MAPK/ERK Signaling in Diabetes Remission Induced by the Central Action of Fibroblast Growth Factor 1 (FGF1)

101-OR: Identification of Warm Sensitive Neurons in the Hypothalamic Preoptic Area as Powerful Regulators of Glucose Homeostasis

98-OR: Cold-Induced Hyperphagia Requires AgRP Neuron Activation

1824-P: Leptin Receptor Neurons in the Hypothalamic Ventromedial Nucleus Play a Physiological Role in Regulating Glucose Tolerance

The Hypothalamic Arcuate Nucleus–Median Eminence Is a Target for Sustained Diabetes Remission Induced by Fibroblast Growth Factor 1

Peripheral Mechanisms Mediating the Sustained Antidiabetic Action of FGF1 in the Brain

Distinct Neuronal Projections From the Hypothalamic Ventromedial Nucleus Mediate Glycemic and Behavioral Effects

An Action in the Hypothalamic Arcuate Nucleus Is Sufficient to Explain the Sustained Remission of Diabetes Induced by Central Administration of Fibroblast Growth Factor-1 (FGF-1)

Sustained Diabetes Remission Induced by the Central Action of Fibroblast Growth Factor-1 (FGF-1) Requires Activation of Integrin Receptor aνß3

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