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Guoqiang Gu
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Journal Articles

Metabolic stress levels influence the ability of the myelin transcription factors to regulate β-cell identity and survival

Xin Tong, Mahircan Yagan, Ruiying Hu, Simone Nevills, Teri D. Stevenson, Roland W. Stein, Appakalai N. Balamurugan, Guoqiang Gu
Journal: Diabetes
Diabetes db230528
https://doi.org/10.2337/db23-0528
Published: 26 July 2024
View article titled, Metabolic stress levels influence the ability of the myelin transcription factors to regulate β-cell identity and survival
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Meeting Abstracts

1731-P: Determining the Mechanistic Relationship between Maternal Diet and Postnatal Beta-Cell Function

SIMONE NEVILLS, GUOQIANG GU
Journal: Diabetes
Diabetes 2023;72(Supplement_1):1731-P
https://doi.org/10.2337/db23-1731-P
Published: 20 June 2023
View article titled, 1731-P: Determining the Mechanistic Relationship between Maternal Diet and Postnatal Beta-Cell Function
Journal Articles

Mitofusins Mfn1 and Mfn2 Are Required to Preserve Glucose- but Not Incretin-Stimulated β-Cell Connectivity and Insulin Secretion

Eleni Georgiadou, Charanya Muralidharan, Michelle Martinez, Pauline Chabosseau, Elina Akalestou, Alejandra Tomas, Fiona Yong Su Wern, Theodoros Stylianides, Asger Wretlind, Cristina Legido-Quigley, Ben Jones, Livia Lopez-Noriega, Yanwen Xu, Guoqiang Gu, Nour Alsabeeh, Céline Cruciani-Guglielmacci, Christophe Magnan, Mark Ibberson, Isabelle Leclerc, Yusuf Ali, Scott A. Soleimanpour, Amelia K. Linnemann, Tristan A. Rodriguez, Guy A. Rutter
Journal: Diabetes
Diabetes 2022;71(7):1472–1489
https://doi.org/10.2337/db21-0800
Published: 26 April 2022
View article titled, Mitofusins <em>Mfn1</em> and <em>Mfn2</em> Are Required to Preserve Glucose- but Not Incretin-Stimulated β-Cell Connectivity and Insulin Secretion
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Journal Articles

Glucose Regulates Microtubule Disassembly and the Dose of Insulin Secretion via Tau Phosphorylation

Kung-Hsien Ho, Xiaodun Yang, Anna B. Osipovich, Over Cabrera, Mansuo L. Hayashi, Mark A. Magnuson, Guoqiang Gu, Irina Kaverina
Journal: Diabetes
Diabetes 2020;69(9):1936–1947
https://doi.org/10.2337/db19-1186
Published: 15 June 2020
View article titled, Glucose Regulates Microtubule Disassembly and the Dose of Insulin Secretion via Tau Phosphorylation
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Journal Articles

Coregulator Sin3a Promotes Postnatal Murine β-Cell Fitness by Regulating Genes in Ca2+ Homeostasis, Cell Survival, Vesicle Biosynthesis, Glucose Metabolism, and Stress Response

Xiaodun Yang, Sarah M. Graff, Cody N. Heiser, Kung-Hsien Ho, Bob Chen, Alan J. Simmons, Austin N. Southard-Smith, Gregory David, David A. Jacobson, Irina Kaverina, Christopher V.E. Wright, Ken S. Lau, Guoqiang Gu
Journal: Diabetes
Diabetes 2020;69(6):1219–1231
https://doi.org/10.2337/db19-0721
Published: 03 April 2020
View article titled, Coregulator Sin3a Promotes Postnatal Murine β-Cell Fitness by Regulating Genes in Ca<sup>2+</sup> Homeostasis, Cell Survival, Vesicle Biosynthesis, Glucose Metabolism, and Stress Response
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Meeting Abstracts

2181-P: Glucose-Induced Hyperphosphorylation of Microtubule-Associated Protein Tau Potentiates Islet Beta-Cell Insulin Secretion by Destabilizing the Microtubule Network

KUNG-HSIEN HO, GUOQIANG GU, IRINA KAVERINA
Journal: Diabetes
Diabetes 2019;68(Supplement_1):2181-P
https://doi.org/10.2337/db19-2181-P
Published: 01 June 2019
View article titled, 2181-P: Glucose-Induced Hyperphosphorylation of Microtubule-Associated Protein Tau Potentiates Islet Beta-Cell Insulin Secretion by Destabilizing the Microtubule Network
Meeting Abstracts

1772-P: Insulin Granule Biogenesis at the Golgi Requires a Metabolically-Regulated, Non-centrosomal Subpopulation of Microtubules

KATHRYN TROGDEN, CHRISTOPHER V. WRIGHT, GUOQIANG GU, IRINA KAVERINA
Journal: Diabetes
Diabetes 2019;68(Supplement_1):1772-P
https://doi.org/10.2337/db19-1772-P
Published: 01 June 2019
View article titled, 1772-P: Insulin Granule Biogenesis at the Golgi Requires a Metabolically-Regulated, Non-centrosomal Subpopulation of Microtubules
Journal Articles

Gαo Represses Insulin Secretion by Reducing Vesicular Docking in Pancreatic β-Cells

Aizhen Zhao, Mica Ohara-Imaizumi, Marcella Brissova, Richard K.P. Benninger, Yanwen Xu, Yuhan Hao, Joel Abramowitz, Guylain Boulay, Alvin C. Powers, David Piston, Meisheng Jiang, Shinya Nagamatsu, Lutz Birnbaumer, Guoqiang Gu
Journal: Diabetes
Diabetes 2010;59(10):2522–2529
https://doi.org/10.2337/db09-1719
Published: 09 July 2010
View article titled, Gαo Represses Insulin Secretion by Reducing Vesicular Docking in Pancreatic β-Cells
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Includes: Supplementary data