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Journal Articles

Genetic Variations in GCKR and PNPLA3 Regulate Metabolic Balance Across the Liver

Available to Purchase
Yunyun Ma, Shiqi Zuo, Therlinder Lo, David Phan, Tyler Finley, Adrienne Mackay, Enrique Trigo, Jaana A. Hartiala, Hooman Allayee, Anny H. Xiang, Thomas A. Buchanan, Richard M. Watanabe
Journal: Diabetes
Diabetes 2025;74(7):1300–1309
https://doi.org/10.2337/db24-0923
Published: 24 April 2025
View articletitled, Genetic Variations in GCKR and PNPLA3 Regulate Metabolic Balance Across the Liver
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Journal Articles

Comprehensive Clinical and Genetic Analyses of Circulating Bile Acids and Their Associations With Diabetes and Its Indices

Available to Purchase
Ibrahim Choucair, Deepthi P. Mallela, James R. Hilser, Jaana A. Hartiala, Ina Nemet, Valentin Gogonea, Lin Li, Aldons J. Lusis, Michael A. Fischbach, W.H. Wilson Tang, Hooman Allayee, Stanley L. Hazen
Journal: Diabetes
Diabetes 2024;73(8):1215–1228
https://doi.org/10.2337/db23-0676
Published: 03 May 2024
View articletitled, Comprehensive Clinical and Genetic Analyses of Circulating Bile Acids and Their Associations With Diabetes and Its Indices
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Journal Articles

Improved Performance of Dynamic Measures of Insulin Response Over Surrogate Indices to Identify Genetic Contributors of Type 2 Diabetes: The GUARDIAN Consortium

Free
Nicholette D. Palmer, Lynne E. Wagenknecht, Carl D. Langefeld, Nan Wang, Thomas A. Buchanan, Anny H. Xiang, Hooman Allayee, Richard N. Bergman, Leslie J. Raffel, Yii-Der Ida Chen, Talin Haritunians, Tasha Fingerlin, Mark O. Goodarzi, Kent D. Taylor, Jerome I. Rotter, Richard M. Watanabe, Donald W. Bowden
Journal: Diabetes
Diabetes 2016;65(7):2072–2080
https://doi.org/10.2337/db15-1543
Published: 03 May 2016
View articletitled, Improved Performance of Dynamic Measures of Insulin Response Over Surrogate Indices to Identify Genetic Contributors of Type 2 Diabetes: The GUARDIAN Consortium
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Includes: Supplementary data
Journal Articles

Subcutaneous Adipose Tissue Macrophage Infiltration Is Associated With Hepatic and Visceral Fat Deposition, Hyperinsulinemia, and Stimulation of NF-κB Stress Pathway

Open Access
Kim-Anne Lê, Swapna Mahurkar, Tanya L. Alderete, Rebecca E. Hasson, Tanja C. Adam, Joon Sung Kim, Elizabeth Beale, Chen Xie, Andrew S. Greenberg, Hooman Allayee, Michael I. Goran
Journal: Diabetes
Diabetes 2011;60(11):2802–2809
https://doi.org/10.2337/db10-1263
Published: 17 October 2011
View articletitled, Subcutaneous Adipose Tissue Macrophage Infiltration Is Associated With Hepatic and Visceral Fat Deposition, Hyperinsulinemia, and Stimulation of NF-κB Stress Pathway
Open the PDF for Subcutaneous Adipose Tissue Macrophage Infiltration Is Associated With Hepatic and Visceral Fat Deposition, Hyperinsulinemia, and Stimulation of NF-κB Stress Pathway in another window
Journal Articles

Effects of PNPLA3 on Liver Fat and Metabolic Profile in Hispanic Children and Adolescents

Open Access
Michael I. Goran, Ryan Walker, Kim-Anne Le, Swapna Mahurkar, Susanna Vikman, Jaimie N. Davis, Donna Spruijt-Metz, Marc J. Weigensberg, Hooman Allayee
Journal: Diabetes
Diabetes 2010;59(12):3127–3130
https://doi.org/10.2337/db10-0554
Published: 17 September 2010
View articletitled, Effects of PNPLA3 on Liver Fat and Metabolic Profile in Hispanic Children and Adolescents
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Journal Articles

Additive Effects of Genetic Variation in GCK and G6PC2 on Insulin Secretion and Fasting Glucose

Open Access
Xia Li, Yu-Hsiang Shu, Anny H. Xiang, Enrique Trigo, Johanna Kuusisto, Jaana Hartiala, Amy J. Swift, Miwa Kawakubo, Heather M. Stringham, Lori L. Bonnycastle, Jean M. Lawrence, Markku Laakso, Hooman Allayee, Thomas A. Buchanan, Richard M. Watanabe
Journal: Diabetes
Diabetes 2009;58(12):2946–2953
https://doi.org/10.2337/db09-0228
Published: 09 September 2009
View articletitled, Additive Effects of Genetic Variation in GCK and G6PC2 on Insulin Secretion and Fasting Glucose
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Journal Articles

Evidence of Interaction Between PPARG2 and HNF4A Contributing to Variation in Insulin Sensitivity in Mexican Americans

Free
Mary Helen Black, Tasha E. Fingerlin, Hooman Allayee, Weiming Zhang, Anny H. Xiang, Enrique Trigo, Jaana Hartiala, Allison B. Lehtinen, Steven M. Haffner, Richard N. Bergman, Richard C. McEachin, Siri L. Kjos, Jean M. Lawrence, Thomas A. Buchanan, Richard M. Watanabe
Journal: Diabetes
Diabetes 2008;57(4):1048–1056
https://doi.org/10.2337/db07-0848
Published: 01 April 2008
View articletitled, Evidence of Interaction Between PPARG2 and HNF4A Contributing to Variation in Insulin Sensitivity in Mexican Americans
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Includes: Supplementary data
Journal Articles

Transcription Factor 7-Like 2 (TCF7L2) Is Associated With Gestational Diabetes Mellitus and Interacts With Adiposity to Alter Insulin Secretion in Mexican Americans

Free
Richard M. Watanabe, Hooman Allayee, Anny H. Xiang, Enrique Trigo, Jaana Hartiala, Jean M. Lawrence, Thomas A. Buchanan
Journal: Diabetes
Diabetes 2007;56(5):1481–1485
https://doi.org/10.2337/db06-1682
Published: 01 May 2007
View articletitled, Transcription Factor 7-Like 2 (TCF7L2) Is Associated With Gestational Diabetes Mellitus and Interacts With Adiposity to Alter Insulin Secretion in Mexican Americans
Open the PDF for Transcription Factor 7-Like 2 (TCF7L2) Is Associated With Gestational Diabetes Mellitus and Interacts With Adiposity to Alter Insulin Secretion in Mexican Americans in another window
Includes: Supplementary data