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Hueng-Sik Choi
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Journal Articles

O-GlcNAcylation of Orphan Nuclear Receptor Estrogen-Related Receptor γ Promotes Hepatic Gluconeogenesis

Jagannath Misra, Don-Kyu Kim, Yoon Seok Jung, Han Byeol Kim, Yong-Hoon Kim, Eun-Kyung Yoo, Byung Gyu Kim, Sunghoon Kim, In-Kyu Lee, Robert A. Harris, Jeong-Sun Kim, Chul-Ho Lee, Jin Won Cho, Hueng-Sik Choi
Journal: Diabetes
Diabetes 2016;65(10):2835–2848
https://doi.org/10.2337/db15-1523
Published: 22 June 2016
View article titled, O-GlcNAcylation of Orphan Nuclear Receptor Estrogen-Related Receptor γ Promotes Hepatic Gluconeogenesis
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Includes: Supplementary data
Journal Articles

Insulin-Inducible SMILE Inhibits Hepatic Gluconeogenesis

Ji-Min Lee, Woo-Young Seo, Hye-Sook Han, Kyoung-Jin Oh, Yong-Soo Lee, Don-Kyu Kim, Seri Choi, Byeong Hun Choi, Robert A. Harris, Chul-Ho Lee, Seung-Hoi Koo, Hueng-Sik Choi
Journal: Diabetes
Diabetes 2016;65(1):62–73
https://doi.org/10.2337/db15-0249
Published: 04 September 2015
View article titled, Insulin-Inducible SMILE Inhibits Hepatic Gluconeogenesis
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Includes: Supplementary data
Journal Articles

B-Cell Translocation Gene 2 Regulates Hepatic Glucose Homeostasis via Induction of Orphan Nuclear Receptor Nur77 in Diabetic Mouse Model

Yong Deuk Kim, Sun-Gyun Kim, Seung-Lark Hwang, Hueng-Sik Choi, Jae-Hoon Bae, Dae-Kyu Song, Seung-Soon Im
Journal: Diabetes
Diabetes 2014;63(6):1870–1880
https://doi.org/10.2337/db13-1368
Published: 15 May 2014
View article titled, B-Cell Translocation Gene 2 Regulates Hepatic Glucose Homeostasis via Induction of Orphan Nuclear Receptor Nur77 in Diabetic Mouse Model
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Journal Articles

Inverse Agonist of Nuclear Receptor ERRγ Mediates Antidiabetic Effect Through Inhibition of Hepatic Gluconeogenesis

Don-Kyu Kim, Gil-Tae Gang, Dongryeol Ryu, Minseob Koh, Yo-Na Kim, Su Sung Kim, Jinyoung Park, Yong-Hoon Kim, Taebo Sim, In-Kyu Lee, Cheol Soo Choi, Seung Bum Park, Chul-Ho Lee, Seung-Hoi Koo, Hueng-Sik Choi
Journal: Diabetes
Diabetes 2013;62(9):3093–3102
https://doi.org/10.2337/db12-0946
Published: 15 August 2013
View article titled, Inverse Agonist of Nuclear Receptor ERRγ Mediates Antidiabetic Effect Through Inhibition of Hepatic Gluconeogenesis
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Includes: Supplementary data
Journal Articles

Disruption of the Cereblon Gene Enhances Hepatic AMPK Activity and Prevents High-Fat Diet–Induced Obesity and Insulin Resistance in Mice

Kwang Min Lee, Seung-Joo Yang, Yong Deuk Kim, Yoo Duk Choi, Jong Hee Nam, Cheol Soo Choi, Hueng-Sik Choi, Chul-Seung Park
Journal: Diabetes
Diabetes 2013;62(6):1855–1864
https://doi.org/10.2337/db12-1030
Published: 17 May 2013
View article titled, Disruption of the Cereblon Gene Enhances Hepatic AMPK Activity and Prevents High-Fat Diet–Induced Obesity and Insulin Resistance in Mice
Open the PDF for Disruption of the Cereblon Gene Enhances Hepatic AMPK Activity and Prevents High-Fat Diet–Induced Obesity and Insulin Resistance in Mice in another window
Includes: Supplementary data
Journal Articles

Metformin Inhibits Growth Hormone–Mediated Hepatic PDK4 Gene Expression Through Induction of Orphan Nuclear Receptor Small Heterodimer Partner

Yong Deuk Kim, Yong-Hoon Kim, Surendar Tadi, Ji Hoon Yu, Yong-Hyeon Yim, Nam Ho Jeoung, Minho Shong, Lothar Hennighausen, Robert A. Harris, In-Kyu Lee, Chul-Ho Lee, Hueng-Sik Choi
Journal: Diabetes
Diabetes 2012;61(10):2484–2494
https://doi.org/10.2337/db11-1665
Published: 13 September 2012
View article titled, Metformin Inhibits Growth Hormone–Mediated Hepatic <em>PDK4</em> Gene Expression Through Induction of Orphan Nuclear Receptor Small Heterodimer Partner
Open the PDF for Metformin Inhibits Growth Hormone–Mediated Hepatic <em>PDK4</em> Gene Expression Through Induction of Orphan Nuclear Receptor Small Heterodimer Partner in another window
Includes: Supplementary data
Journal Articles

Pharmacological Stimulation of NADH Oxidation Ameliorates Obesity and Related Phenotypes in Mice

Jung Hwan Hwang, Dong Wook Kim, Eun Jin Jo, Yong Kyung Kim, Young Suk Jo, Ji Hoon Park, Sang Ku Yoo, Myung Kyu Park, Tae Hwan Kwak, Young Lim Kho, Jin Han, Hueng-Sik Choi, Sang-Hee Lee, Jin Man Kim, InKyu Lee, Taeyoon Kyung, Cholsoon Jang, Jongkyeong Chung, Gi Ryang Kweon, Minho Shong
Journal: Diabetes
Diabetes 2009;58(4):965–974
https://doi.org/10.2337/db08-1183
Published: 09 January 2009
View article titled, Pharmacological Stimulation of NADH Oxidation Ameliorates Obesity and Related Phenotypes in Mice
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Includes: Supplementary data
Journal Articles

Metformin Inhibits Hepatic Gluconeogenesis Through AMP-Activated Protein Kinase–Dependent Regulation of the Orphan Nuclear Receptor SHP

Yong Deuk Kim, Keun-Gyu Park, Yong-Soo Lee, Yun-Yong Park, Don-Kyu Kim, Balachandar Nedumaran, Won Gu Jang, Won-Jea Cho, Joohun Ha, In-Kyu Lee, Chul-Ho Lee, Hueng-Sik Choi
Journal: Diabetes
Diabetes 2008;57(2):306–314
https://doi.org/10.2337/db07-0381
Published: 01 February 2008
View article titled, Metformin Inhibits Hepatic Gluconeogenesis Through AMP-Activated Protein Kinase–Dependent Regulation of the Orphan Nuclear Receptor SHP
Open the PDF for Metformin Inhibits Hepatic Gluconeogenesis Through AMP-Activated Protein Kinase–Dependent Regulation of the Orphan Nuclear Receptor SHP in another window
Includes: Supplementary data
Journal Articles

Glucotoxicity in the INS-1 Rat Insulinoma Cell Line Is Mediated by the Orphan Nuclear Receptor Small Heterodimer Partner

Keun-Gyu Park, Kyeong-Min Lee, Hye-Young Seo, Ji-Ho Suh, Hye-Soon Kim, Li Wang, Kyu-Chang Won, Hyoung-Woo Lee, Joong-Yeol Park, Ki-Up Lee, Jung-Guk Kim, Bo-Wan Kim, Hueng-Sik Choi, In-Kyu Lee
Journal: Diabetes
Diabetes 2007;56(2):431–437
https://doi.org/10.2337/db06-0753
Published: 01 February 2007
View article titled, Glucotoxicity in the INS-1 Rat Insulinoma Cell Line Is Mediated by the Orphan Nuclear Receptor Small Heterodimer Partner
Open the PDF for Glucotoxicity in the INS-1 Rat Insulinoma Cell Line Is Mediated by the Orphan Nuclear Receptor Small Heterodimer Partner in another window
Includes: Supplementary data