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Ira D Goldfine
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Journal Articles

A New Road for Treating the Vascular Complications of Diabetes: So Let's Step on the Gas

Open Access
Joseph L. Evans, Ira D. Goldfine
Journal: Diabetes
Diabetes 2016;65(2):346–348
https://doi.org/10.2337/dbi15-0029
Published: 13 January 2016
View articletitled, A New Road for Treating the Vascular Complications of Diabetes: So Let's Step on the Gas
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Journal Articles

Aging and Insulin Resistance: Just Say iNOS

Open Access
Joseph L. Evans, Ira D. Goldfine
Journal: Diabetes
Diabetes 2013;62(2):346–348
https://doi.org/10.2337/db12-1239
Published: 17 January 2013
View articletitled, Aging and Insulin Resistance: Just Say iNOS
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Journal Articles

Comment on: Marquez et al. Low-Frequency Variants in HMGA1 Are Not Associated With Type 2 Diabetes Risk. Diabetes 2012;61:524–530

Open Access
Antonio Brunetti, Eusebio Chiefari, Clive R. Pullinger, Sinan Tanyolac, Daniela Foti, Vincent Durlach, Ira D. Goldfine
Journal: Diabetes
Diabetes 2012;61(5):e3
https://doi.org/10.2337/db12-0051
Published: 13 April 2012
View articletitled, Comment on: Marquez et al. Low-Frequency Variants in HMGA1 Are Not Associated With Type 2 Diabetes Risk. Diabetes 2012;61:524–530
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Journal Articles

A Fully Human, Allosteric Monoclonal Antibody That Activates the Insulin Receptor and Improves Glycemic Control

Open Access
Vinay Bhaskar, Ira D. Goldfine, Daniel H. Bedinger, Angela Lau, Hua F. Kuan, Lisa M. Gross, Masahisa Handa, Betty A. Maddux, Susan R. Watson, Shirley Zhu, Ajay J. Narasimha, Raphael Levy, Lynn Webster, Sujeewa D. Wijesuriya, Naichi Liu, Xiaorong Wu, David Chemla-Vogel, Catarina Tran, Steve R. Lee, Steve Wong, Diane Wilcock, Mark L. White, John A. Corbin
Journal: Diabetes
Diabetes 2012;61(5):1263–1271
https://doi.org/10.2337/db11-1578
Published: 13 April 2012
View articletitled, A Fully Human, Allosteric Monoclonal Antibody That Activates the Insulin Receptor and Improves Glycemic Control
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Journal Articles

Increased Hepatic Levels of the Insulin Receptor Inhibitor, PC-1/NPP1, Induce Insulin Resistance and Glucose Intolerance

Free
Hengjiang Dong, Betty A. Maddux, Jennifer Altomonte, Marcia Meseck, Domenico Accili, Robert Terkeltaub, Kristen Johnson, Jack F. Youngren, Ira D. Goldfine
Journal: Diabetes
Diabetes 2005;54(2):367–372
https://doi.org/10.2337/diabetes.54.2.367
Published: 01 February 2005
View articletitled, Increased Hepatic Levels of the Insulin Receptor Inhibitor, PC-1/NPP1, Induce Insulin Resistance and Glucose Intolerance
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Journal Articles

Are Oxidative Stress−Activated Signaling Pathways Mediators of Insulin Resistance and β-Cell Dysfunction?

Free
Joseph L. Evans, Ira D. Goldfine, Betty A. Maddux, Gerold M. Grodsky
Journal: Diabetes
Diabetes 2003;52(1):1–8
https://doi.org/10.2337/diabetes.52.1.1
Published: 01 January 2003
View articletitled, Are Oxidative Stress−Activated Signaling Pathways Mediators of Insulin Resistance and β-Cell Dysfunction?
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Journal Articles

Small Molecule Insulin Receptor Activators Potentiate Insulin Action in Insulin-Resistant Cells

Free
Ming Li, Jack F. Youngren, Vara Prasad Manchem, Michael Kozlowski, Bei B. Zhang, Betty A. Maddux, Ira D. Goldfine
Journal: Diabetes
Diabetes 2001;50(10):2323–2328
https://doi.org/10.2337/diabetes.50.10.2323
Published: 01 October 2001
View articletitled, Small Molecule Insulin Receptor Activators Potentiate Insulin Action in Insulin-Resistant Cells
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Journal Articles

A Novel Small Molecule That Directly Sensitizes the Insulin Receptor In Vitro and In Vivo

Free
Vara Prasad Manchem, Ira D. Goldfine, Ronald A. Kohanski, Cristina P. Cristobal, Robert T. Lum, Steven R. Schow, Songyuan Shi, Wayne R. Spevak, Edgardo Laborde, Deborah K. Toavs, Hugo O. Villar, Michael M. Wick, Michael R. Kozlowski
Journal: Diabetes
Diabetes 2001;50(4):824–830
https://doi.org/10.2337/diabetes.50.4.824
Published: 01 April 2001
View articletitled, A Novel Small Molecule That Directly Sensitizes the Insulin Receptor In Vitro and In Vivo
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Journal Articles

Protection Against Oxidative Stress—Induced Insulin Resistance in Rat L6 Muscle Cells by Micromolar Concentrations of α-Lipoic Acid

Free
Betty A. Maddux, Wendy See, John C. Lawrence, Jr., Amy L. Goldfine, Ira D. Goldfine, Joseph L. Evans
Journal: Diabetes
Diabetes 2001;50(2):404–410
https://doi.org/10.2337/diabetes.50.2.404
Published: 01 February 2001
View articletitled, Protection Against Oxidative Stress—Induced Insulin Resistance in Rat L6 Muscle Cells by Micromolar Concentrations of α-Lipoic Acid
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Journal Articles

Skeletal Muscle Content of Membrane Glycoprotein PC-1 in Obesity: Relationship to Muscle Glucose Transport

Free
Jack F Youngren, Betty A Maddux, Shlomo Sasson, Paolo Sbraccia, Edward B Tapscott, Melvin S Swanson, G Lynis Dohm, Ira D Goldfine
Journal: Diabetes
Diabetes 1996;45(10):1324–1328
https://doi.org/10.2337/diab.45.10.1324
Published: 01 October 1996
View articletitled, Skeletal Muscle Content of Membrane Glycoprotein PC-1 in Obesity: Relationship to Muscle Glucose Transport
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Journal Articles

Evidence That Two Naturally Occurring Human Insulin Receptor α-Subunit Variants Are Immunologically Distinct

Free
Giorgio Sesti, Maria Adelaide Marini, Antonio Montemurro, Luigi Condorelli, Patrizia Borboni, Hans-Ulrich Haring, Axel Ullrich, Ira D Goldfine, Roberto De Pirro, Renato Lauro
Journal: Diabetes
Diabetes 1992;41(1):6–11
https://doi.org/10.2337/diab.41.1.6
Published: 01 January 1992
View articletitled, Evidence That Two Naturally Occurring Human Insulin Receptor α-Subunit Variants Are Immunologically Distinct
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Journal Articles

Production of Inhibitor of Insulin-Receptor Tyrosine Kinase in Fibroblasts From Patient With Insulin Resistance and NIDDM

Free
Paolo Sbraccia, Patricia A Goodman, Betty A Maddux, K Y Wong, Y-D I Chen, Gerald M Reaven, Ira D Goldfine
Journal: Diabetes
Diabetes 1991;40(2):295–299
https://doi.org/10.2337/diab.40.2.295
Published: 01 February 1991
View articletitled, Production of Inhibitor of Insulin-Receptor Tyrosine Kinase in Fibroblasts From Patient With Insulin Resistance and NIDDM
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Journal Articles

Archaeology of NIDDM: Excavation of the “Thrifty” Genotype

Free
Michael Wendorf, Ira D Goldfine
Journal: Diabetes
Diabetes 1991;40(2):161–165
https://doi.org/10.2337/diab.40.2.161
Published: 01 February 1991
View articletitled, Archaeology of NIDDM: Excavation of the “Thrifty” Genotype
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Journal Articles

Mechanisms of Insulin-Induced Insulin-Receptor Downregulation: Decrease of Receptor Biosynthesis and mRNA Levels

Free
Yoshinori Okabayashi, Betty A Maddux, Alexander R McDonald, Craig D Logsdon, John A Williams, Ira D Goldfine
Journal: Diabetes
Diabetes 1989;38(2):182–187
https://doi.org/10.2337/diab.38.2.182
Published: 01 February 1989
View articletitled, Mechanisms of Insulin-Induced Insulin-Receptor Downregulation: Decrease of Receptor Biosynthesis and mRNA Levels
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Journal Articles

Sequence and Analysis of Promoter Region of Human Insulin-Receptor Gene

Free
Paul W Mamula, Kwok-Ying Wong, Betty A Maddux, Alexander R McDonald, Ira D Goldfine
Journal: Diabetes
Diabetes 1988;37(9):1241–1246
https://doi.org/10.2337/diab.37.9.1241
Published: 01 September 1988
View articletitled, Sequence and Analysis of Promoter Region of Human Insulin-Receptor Gene
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Journal Articles

Insulin and Other Stimulants Have Nonparallel Translational Effects on Protein Synthesis

Free
Yoshinori Okabayashi, Joachim Moessner, Craig D Logsdon, Ira D Goldfine, John A Williams
Journal: Diabetes
Diabetes 1987;36(9):1054–1060
https://doi.org/10.2337/diab.36.9.1054
Published: 01 September 1987
View articletitled, Insulin and Other Stimulants Have Nonparallel Translational Effects on Protein Synthesis
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Journal Articles

Regulation of Insulin-Receptor mRNA Levels by Glucocorticoids

Free
Alex R McDonald, Betty A Maddux, Y Okabayashi, K Y Wong, D M Hawley, Craig D Logsdon, Ira D Goldfine
Journal: Diabetes
Diabetes 1987;36(6):779–781
https://doi.org/10.2337/diab.36.6.779
Published: 01 June 1987
View articletitled, Regulation of Insulin-Receptor mRNA Levels by Glucocorticoids
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Journal Articles

Biosynthesis and Processing of the Human Insulin Receptor

Free
John Forsayeth, Betty Maddux, Ira D Goldfine
Journal: Diabetes
Diabetes 1986;35(7):837–846
https://doi.org/10.2337/diab.35.7.837
Published: 01 July 1986
View articletitled, Biosynthesis and Processing of the Human Insulin Receptor
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Journal Articles

Evidence That Cholecystokinin Interacts with Specific Receptors and Regulates Insulin Release in Isolated Rat Islets of Langerhans

Free
Eugen J Verspohl, Hermann P T Ammon, John A Williams, Ira D Goldfine
Journal: Diabetes
Diabetes 1986;35(1):38–43
https://doi.org/10.2337/diab.35.1.38
Published: 01 January 1986
View articletitled, Evidence That Cholecystokinin Interacts with Specific Receptors and Regulates Insulin Release in Isolated Rat Islets of Langerhans
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Journal Articles

Tissue-specific Antibodies Against the Fibroblast Insulin Receptor in a Patient with Lupus Nephritis and Hypoglycemia

Free
Roberto De Pirro, Patrizia Borboni, Renato Lauro, Antonella Festa, Ivano Testa, Carlo De Martinis, Betty A Maddux, Ira D Goldfine
Journal: Diabetes
Diabetes 1985;34(11):1088–1091
https://doi.org/10.2337/diab.34.11.1088
Published: 01 November 1985
View articletitled, Tissue-specific Antibodies Against the Fibroblast Insulin Receptor in a Patient with Lupus Nephritis and Hypoglycemia
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