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Irene Cozar-Castellano
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Meeting Abstracts

1593-P: Insulin-Degrading Enzyme (IDE) Regulates Glucagon Signalling and Mitochondrial Respiration in Hepatocytes

CARLOS M. GONZÁLEZ-CASIMIRO, PATRICIA CÁMARA-TORRES, BEATRIZ MERINO, JAIME SANTO-DOMINGO, MIGUEL A. DE LA FUENTE, ANDRÉS ALONSO, IRENE COZAR-CASTELLANO, GERMAN PERDOMO
Journal: Diabetes
Diabetes 2023;72(Supplement_1):1593-P
https://doi.org/10.2337/db23-1593-P
Published: 20 June 2023
View article titled, 1593-P: Insulin-Degrading Enzyme (IDE) Regulates Glucagon Signalling and Mitochondrial Respiration in Hepatocytes
Meeting Abstracts

200-OR: Role of Insulin-Degrading Enzyme (IDE) in the Tubulin–Primary Cilium Axis to Regulate Glucagon Secretion

ELENA CASANUEVA-ALVAREZ, ALBA SANZ-GONZÁLEZ, BEATRIZ MERINO, GERMAN PERDOMO, IRENE COZAR-CASTELLANO
Journal: Diabetes
Diabetes 2023;72(Supplement_1):200-OR
https://doi.org/10.2337/db23-200-OR
Published: 20 June 2023
View article titled, 200-OR: Role of Insulin-Degrading Enzyme (IDE) in the Tubulin–Primary Cilium Axis to Regulate Glucagon Secretion
Journal Articles

Induction of Human β-Cell Proliferation and Engraftment Using a Single G1/S Regulatory Molecule, cdk6

Nathalie M. Fiaschi-Taesch, Fatimah Salim, Jeffrey Kleinberger, Ronnie Troxell, Irene Cozar-Castellano, Karen Selk, Edward Cherok, Karen K. Takane, Donald K. Scott, Andrew F. Stewart
Journal: Diabetes
Diabetes 2010;59(8):1926–1936
https://doi.org/10.2337/db09-1776
Published: 01 August 2010
View article titled, Induction of Human β-Cell Proliferation and Engraftment Using a Single G1/S Regulatory Molecule, cdk6
Open the PDF for Induction of Human β-Cell Proliferation and Engraftment Using a Single G1/S Regulatory Molecule, cdk6 in another window
Includes: Supplementary data
Journal Articles

Survey of the Human Pancreatic β-Cell G1/S Proteome Reveals a Potential Therapeutic Role for Cdk-6 and Cyclin D1 in Enhancing Human β-Cell Replication and Function In Vivo

Nathalie Fiaschi-Taesch, Todd A. Bigatel, Brian Sicari, Karen K. Takane, Fatima Salim, Silvia Velazquez-Garcia, George Harb, Karen Selk, Irene Cozar-Castellano, Andrew F. Stewart
Journal: Diabetes
Diabetes 2009;58(4):882–893
https://doi.org/10.2337/db08-0631
Published: 09 January 2009
View article titled, Survey of the Human Pancreatic β-Cell G1/S Proteome Reveals a Potential Therapeutic Role for Cdk-6 and Cyclin D<sub>1</sub> in Enhancing Human β-Cell Replication and Function In Vivo
Open the PDF for Survey of the Human Pancreatic β-Cell G1/S Proteome Reveals a Potential Therapeutic Role for Cdk-6 and Cyclin D<sub>1</sub> in Enhancing Human β-Cell Replication and Function In Vivo in another window
Includes: Supplementary data
Journal Articles

Lessons From the First Comprehensive Molecular Characterization of Cell Cycle Control in Rodent Insulinoma Cell Lines

Irene Cozar-Castellano, George Harb, Karen Selk, Karen Takane, Rupangi Vasavada, Brian Sicari, Brian Law, Pili Zhang, Donald K. Scott, Nathalie Fiaschi-Taesch, Andrew F. Stewart
Journal: Diabetes
Diabetes 2008;57(11):3056–3068
https://doi.org/10.2337/db08-0393
Published: 01 November 2008
View article titled, Lessons From the First Comprehensive Molecular Characterization of Cell Cycle Control in Rodent Insulinoma Cell Lines
Open the PDF for Lessons From the First Comprehensive Molecular Characterization of Cell Cycle Control in Rodent Insulinoma Cell Lines in another window
Includes: Supplementary data
Journal Articles

Tissue-Specific Deletion of the Retinoblastoma Protein in the Pancreatic β-Cell Has Limited Effects on β-Cell Replication, Mass, and Function

Rupangi C. Vasavada, Irene Cozar-Castellano, Darinka Sipula, Andrew F. Stewart
Journal: Diabetes
Diabetes 2007;56(1):57–64
https://doi.org/10.2337/db06-0517
Published: 01 January 2007
View article titled, Tissue-Specific Deletion of the Retinoblastoma Protein in the Pancreatic β-Cell Has Limited Effects on β-Cell Replication, Mass, and Function
Open the PDF for Tissue-Specific Deletion of the Retinoblastoma Protein in the Pancreatic β-Cell Has Limited Effects on β-Cell Replication, Mass, and Function in another window
Includes: Supplementary data
Journal Articles

The Cell Cycle Inhibitory Protein p21cip Is Not Essential for Maintaining β-Cell Cycle Arrest or β-Cell Function In Vivo

Irene Cozar-Castellano, Marcia Haught, Andrew F. Stewart
Journal: Diabetes
Diabetes 2006;55(12):3271–3278
https://doi.org/10.2337/db06-0627
Published: 01 December 2006
View article titled, The Cell Cycle Inhibitory Protein p21<sup>cip</sup> Is Not Essential for Maintaining β-Cell Cycle Arrest or β-Cell Function In Vivo
Open the PDF for The Cell Cycle Inhibitory Protein p21<sup>cip</sup> Is Not Essential for Maintaining β-Cell Cycle Arrest or β-Cell Function In Vivo in another window
Journal Articles

Evaluation of β-Cell Replication in Mice Transgenic for Hepatocyte Growth Factor and Placental Lactogen: Comprehensive Characterization of the G1/S Regulatory Proteins Reveals Unique Involvement of p21cip

Irene Cozar-Castellano, Matthew Weinstock, Marcia Haught, Silvia Velázquez-Garcia, Darinka Sipula, Andrew F. Stewart
Journal: Diabetes
Diabetes 2006;55(1):70–77
https://doi.org/10.2337/diabetes.55.01.06.db05-0632
Published: 01 January 2006
View article titled, Evaluation of β-Cell Replication in Mice Transgenic for Hepatocyte Growth Factor and Placental Lactogen: <subtitle>Comprehensive Characterization of the G<sub>1</sub>/S Regulatory Proteins Reveals Unique Involvement of p21<sup>cip</sup></subtitle>
Open the PDF for Evaluation of β-Cell Replication in Mice Transgenic for Hepatocyte Growth Factor and Placental Lactogen: <subtitle>Comprehensive Characterization of the G<sub>1</sub>/S Regulatory Proteins Reveals Unique Involvement of p21<sup>cip</sup></subtitle> in another window
Includes: Supplementary data
Journal Articles

Induction of β-Cell Proliferation and Retinoblastoma Protein Phosphorylation in Rat and Human Islets Using Adenovirus-Mediated Transfer of Cyclin-Dependent Kinase-4 and Cyclin D1

Irene Cozar-Castellano, Karen K. Takane, Rita Bottino, A.N. Balamurugan, Andrew F. Stewart
Journal: Diabetes
Diabetes 2004;53(1):149–159
https://doi.org/10.2337/diabetes.53.1.149
Published: 01 January 2004
View article titled, Induction of β-Cell Proliferation and Retinoblastoma Protein Phosphorylation in Rat and Human Islets Using Adenovirus-Mediated Transfer of Cyclin-Dependent Kinase-4 and Cyclin D<sub>1</sub>
Open the PDF for Induction of β-Cell Proliferation and Retinoblastoma Protein Phosphorylation in Rat and Human Islets Using Adenovirus-Mediated Transfer of Cyclin-Dependent Kinase-4 and Cyclin D<sub>1</sub> in another window