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Iseki Takamoto
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Journal Articles

Overexpression of UBE2E2 in Mouse Pancreatic β-Cells Leads to Glucose Intolerance via Reduction of β-Cell Mass

Yoshitaka Sakurai, Naoto Kubota, Iseki Takamoto, Nobuhiro Wada, Masakazu Aihara, Takanori Hayashi, Tetsuya Kubota, Yuta Hiraike, Takayoshi Sasako, Harumi Nakao, Atsu Aiba, Yoko Chikaoka, Takeshi Kawamura, Takashi Kadowaki, Toshimasa Yamauchi
Journal: Diabetes
Diabetes 2024;73(3):474–489
https://doi.org/10.2337/db23-0150
Published: 08 December 2023
View article titled, Overexpression of UBE2E2 in Mouse Pancreatic β-Cells Leads to Glucose Intolerance via Reduction of β-Cell Mass
Open the PDF for Overexpression of UBE2E2 in Mouse Pancreatic β-Cells Leads to Glucose Intolerance via Reduction of β-Cell Mass in another window
Journal Articles

Lack of Brain Insulin Receptor Substrate-1 Causes Growth Retardation, With Decreased Expression of Growth Hormone–Releasing Hormone in the Hypothalamus

Takanori Hayashi, Tetsuya Kubota, Inoue Mariko, Iseki Takamoto, Masakazu Aihara, Yoshitaka Sakurai, Nobuhiro Wada, Takashi Miki, Toshimasa Yamauchi, Naoto Kubota, Takashi Kadowaki
Journal: Diabetes
Diabetes 2021;70(8):1640–1653
https://doi.org/10.2337/db20-0482
Published: 12 May 2021
View article titled, Lack of Brain Insulin Receptor Substrate-1 Causes Growth Retardation, With Decreased Expression of Growth Hormone–Releasing Hormone in the Hypothalamus
Open the PDF for Lack of Brain Insulin Receptor Substrate-1 Causes Growth Retardation, With Decreased Expression of Growth Hormone–Releasing Hormone in the Hypothalamus in another window
Meeting Abstracts

Impairment of M2a-Subtype Macrophage Activation by Il-4-Irs2 Pathway in Obesity

TETSUYA KUBOTA, MARIKO INOUE, NAOTO KUBOTA, ISEKI TAKAMOTO, KOHJIRO UEKI, TOSHIMASA YAMAUCHI, TAKASHI KADOWAKI
Journal: Diabetes
Diabetes 2018;67(Supplement_1):2012-P
https://doi.org/10.2337/db18-2012-P
Published: 01 July 2018
View article titled, Impairment of M2a-Subtype Macrophage Activation by Il-4-Irs2 Pathway in Obesity
Meeting Abstracts

Tofogliflozin Suppresses the Progression of Atherosclerosis and Reduces Inflammation in Macrophages of STZ-Diabetic ApoE KO Mice due to Improvement of Glucose Tolerance

MASAHIKO IWAMOTO, NAOTO KUBOTA, TETSUYA KUBOTA, YOSHITAKA SAKURAI, NOBUHIRO WADA, ISEKI TAKAMOTO, SEIJI SHIODA, TAKASHI KADOWAKI
Journal: Diabetes
Diabetes 2018;67(Supplement_1):486-P
https://doi.org/10.2337/db18-486-P
Published: 01 July 2018
View article titled, Tofogliflozin Suppresses the Progression of Atherosclerosis and Reduces Inflammation in Macrophages of STZ-Diabetic ApoE KO Mice due to Improvement of Glucose Tolerance
Journal Articles

Dual Regulation of Gluconeogenesis by Insulin and Glucose in the Proximal Tubules of the Kidney

Motohiro Sasaki, Takayoshi Sasako, Naoto Kubota, Yoshitaka Sakurai, Iseki Takamoto, Tetsuya Kubota, Reiko Inagi, George Seki, Moritaka Goto, Kohjiro Ueki, Masaomi Nangaku, Takahito Jomori, Takashi Kadowaki
Journal: Diabetes
Diabetes 2017;66(9):2339–2350
https://doi.org/10.2337/db16-1602
Published: 17 June 2017
View article titled, Dual Regulation of Gluconeogenesis by Insulin and Glucose in the Proximal Tubules of the Kidney
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Includes: Supplementary data
Journal Articles

Insulin Receptor Substrate-2 (Irs2) in Endothelial Cells Plays a Crucial Role in Insulin Secretion

Shinji Hashimoto, Naoto Kubota, Hiroyuki Sato, Motohiro Sasaki, Iseki Takamoto, Tetsuya Kubota, Keizo Nakaya, Mitsuhiko Noda, Kohjiro Ueki, Takashi Kadowaki
Journal: Diabetes
Diabetes 2015;64(3):876–886
https://doi.org/10.2337/db14-0432
Published: 01 October 2014
View article titled, Insulin Receptor Substrate-2 (Irs2) in Endothelial Cells Plays a Crucial Role in Insulin Secretion
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Journal Articles

Pioglitazone Reduces Islet Triglyceride Content and Restores Impaired Glucose-Stimulated Insulin Secretion in Heterozygous Peroxisome Proliferator–Activated Receptor-γ–Deficient Mice on a High-Fat Diet

Junji Matsui, Yasuo Terauchi, Naoto Kubota, Iseki Takamoto, Kazuhiro Eto, Tokuyuki Yamashita, Kajuro Komeda, Toshimasa Yamauchi, Junji Kamon, Shunbun Kita, Mitsuhiko Noda, Takashi Kadowaki
Journal: Diabetes
Diabetes 2004;53(11):2844–2854
https://doi.org/10.2337/diabetes.53.11.2844
Published: 01 November 2004
View article titled, Pioglitazone Reduces Islet Triglyceride Content and Restores Impaired Glucose-Stimulated Insulin Secretion in Heterozygous Peroxisome Proliferator–Activated Receptor-γ–Deficient Mice on a High-Fat Diet
Open the PDF for Pioglitazone Reduces Islet Triglyceride Content and Restores Impaired Glucose-Stimulated Insulin Secretion in Heterozygous Peroxisome Proliferator–Activated Receptor-γ–Deficient Mice on a High-Fat Diet in another window