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Meeting Abstracts

2092-LB: Receptor-Mediated G12 Signaling Strongly Promotes Insulin Secretion from Pancreatic Beta Cells

SRINIVAS PITTALA, DHANUSH HASPULA, LIU LIU, YINGHONG CUI, JÜRGEN WESS

Diabetes 2024;73(Supplement_1):2092-LB

https://doi.org/10.2337/db24-2092-LB

Published: 14 June 2024

View article titled, 2092-LB: Receptor-Mediated G12 Signaling Strongly Promotes Insulin Secretion from Pancreatic Beta Cells

Meeting Abstracts

2055-LB: Temporal Resolution of Single-Cell Transcriptomics and Epigenomics of Murine Pancreatic Islet in Diet-Induced Obesity

SIMRAN SINGH, KRUSHNA PAVAN MUSALE, LUIZ F. BARELLA, AJITA SHREE, HAMIM ZAFAR, JÜRGEN WESS, SAI PRASAD PYDI

Diabetes 2024;73(Supplement_1):2055-LB

https://doi.org/10.2337/db24-2055-LB

Published: 14 June 2024

View article titled, 2055-LB: Temporal Resolution of Single-Cell Transcriptomics and Epigenomics of Murine Pancreatic Islet in Diet-Induced Obesity

Journal Articles

An Intraislet Paracrine Signaling Pathway That Enables Glucagon to Stimulate Pancreatic β-Cells

Alejandro Caicedo, Mark O. Huising, Jürgen Wess

Diabetes 2023;72(12):1748–1750

https://doi.org/10.2337/dbi23-0023

Published: 20 November 2023

View article titled, An Intraislet Paracrine Signaling Pathway That Enables Glucagon to Stimulate Pancreatic β-Cells

Journal Articles

Adipocyte G Protein–Coupled Receptors as Potential Targets for Novel Antidiabetic Drugs

Liu Liu, Jürgen Wess

Diabetes 2023;72(7):825–834

https://doi.org/10.2337/db23-0095

Published: 20 June 2023

View article titled, Adipocyte G Protein–Coupled Receptors as Potential Targets for Novel Antidiabetic Drugs

Meeting Abstracts

32-OR: Receptor-Mediated Gq Signaling in Adipocytes as a Critical Modulator of Systemic Glucose and Lipid Homeostasis

TAKEFUMI KIMURA, SAI PRASAD PYDI, LEI WANG, YINGHONG CUI, OKSANA GAVRILOVA, JÜRGEN WESS

Diabetes 2021;70(Supplement_1):32-OR

https://doi.org/10.2337/db21-32-OR

Published: 01 June 2021

View article titled, 32-OR: Receptor-Mediated Gq Signaling in Adipocytes as a Critical Modulator of Systemic Glucose and Lipid Homeostasis

Meeting Abstracts

1694-P: Beta-Arrestin 1 Suppresses Myogenic Reprogramming of Brown Fat to Maintain Euglycemia

SAI PRASAD PYDI, SHANU JAIN, LUIZ F. BARELLA, JAROSLAWNA MEISTER, LEI WANG, YINGHONG CUI, OKSANA GAVRILOVA, JÜRGEN WESS

Diabetes 2020;69(Supplement_1):1694-P

https://doi.org/10.2337/db20-1694-P

Published: 01 June 2020

View article titled, 1694-P: Beta-Arrestin 1 Suppresses Myogenic Reprogramming of Brown Fat to Maintain Euglycemia

Meeting Abstracts

2129-P: Glucagon Secretion from Pancreatic Islets Is Regulated by Beta-Arrestin-1

DIPTADIP DATTAROY, LUIZ F. BARELLA, SAI PRASAD PYDI, YINGHONG CUI, KLAUS H. KAESTNER, JÜRGEN WESS

Diabetes 2020;69(Supplement_1):2129-P

https://doi.org/10.2337/db20-2129-P

Published: 01 June 2020

View article titled, 2129-P: Glucagon Secretion from Pancreatic Islets Is Regulated by Beta-Arrestin-1

Meeting Abstracts

1971-P: Activation of Adipocyte Gq Signaling Causes Improved Whole-Body Glucose Homeostasis

TAKEFUMI KIMURA, SAI PRASAD PYDI, LEI WANG, YINGHONG CUI, OKSANA GAVRILOVA, JÜRGEN WESS

Diabetes 2020;69(Supplement_1):1971-P

https://doi.org/10.2337/db20-1971-P

Published: 01 June 2020

View article titled, 1971-P: Activation of Adipocyte Gq Signaling Causes Improved Whole-Body Glucose Homeostasis

Meeting Abstracts

38-OR: Beta-Arrestin-1 Regulates Pancreatic Beta-Cell Function and Plays a Key Role in Maintaining Whole Body Glucose Homeostasis

LUIZ F. BARELLA, MARIO ROSSI, SAI PRASAD PYDI, SHANU JAIN, LU ZHU, WEI CHEN, JÜRGEN WESS

Diabetes 2019;68(Supplement_1):38-OR

https://doi.org/10.2337/db19-38-OR

Published: 01 June 2019

View article titled, 38-OR: Beta-Arrestin-1 Regulates Pancreatic Beta-Cell Function and Plays a Key Role in Maintaining Whole Body Glucose Homeostasis

Meeting Abstracts

1781-P: Adipocyte GI Signaling Regulates Whole-Body Glucose Homeostasis and Insulin Sensitivity

LEI WANG, SAI PRASAD PYDI, LU ZHU, SHANU JAIN, YINGHONG CUI, OKSANA GAVRILOVA, JÜRGEN WESS

Diabetes 2019;68(Supplement_1):1781-P

https://doi.org/10.2337/db19-1781-P

Published: 01 June 2019

View article titled, 1781-P: Adipocyte GI Signaling Regulates Whole-Body Glucose Homeostasis and Insulin Sensitivity

Meeting Abstracts

1797-P: ß-arrestin-1 in AgRP Neurons Plays Crucial Role in Maintaining Whole Body Glucose Homeostasis

SAI PRASAD PYDI, ZHENZHONG CUI, LUIZ F. BARELLA, YINGHONG CUI, WEI CHEN, OKSANA GAVRILOVA, JÜRGEN WESS

Diabetes 2019;68(Supplement_1):1797-P

https://doi.org/10.2337/db19-1797-P

Published: 01 June 2019

View article titled, 1797-P: ß-arrestin-1 in AgRP Neurons Plays Crucial Role in Maintaining Whole Body Glucose Homeostasis

Journal Articles

Skeletal Muscle–Specific Activation of G_q Signaling Maintains Glucose Homeostasis

Derek B.J. Bone, Jaroslawna Meister, Jonas R. Knudsen, Diptadip Dattaroy, Amanda Cohen, Regina Lee, Huiyan Lu, Daniel Metzger, Thomas E. Jensen, Jürgen Wess

Diabetes 2019;68(6):1341–1352

https://doi.org/10.2337/db18-0796

Published: 01 April 2019

View article titled, Skeletal Muscle–Specific Activation of G<sub>q</sub> Signaling Maintains Glucose Homeostasis

Includes: Supplementary data

Meeting Abstracts

A Positive Allosteric Modulator Enhances the Ability of Beta Cell M3 Muscarinic Receptors to Simulate Insulin Secretion In Vitro and In Vivo

LU ZHU, JÜRGEN WESS

Diabetes 2018;67(Supplement_1):1767-P

https://doi.org/10.2337/db18-1767-P

Published: 01 July 2018

View article titled, A Positive Allosteric Modulator Enhances the Ability of Beta Cell M3 Muscarinic Receptors to Simulate Insulin Secretion In Vitro and In Vivo

Meeting Abstracts

Polymorphic Role of P2Y₆ Receptor in Insulin Sensitive Organs—Adipose Tissue and Skeletal Muscle

SHANU JAIN, JÜRGEN WESS, KENNETH A. JACOBSON

Diabetes 2018;67(Supplement_1):1769-P

https://doi.org/10.2337/db18-1769-P

Published: 01 July 2018

View article titled, Polymorphic Role of P2Y<sub>6</sub> Receptor in Insulin Sensitive Organs—Adipose Tissue and Skeletal Muscle

Meeting Abstracts

Adipocyte-Selective Deletion of ß-Arrestin-1 in Mice Causes Adiposity, Impaired Glucose Tolerance, and Reduced Insulin Sensitivity

SAI PRASAD PYDI, JÜRGEN WESS

Diabetes 2018;67(Supplement_1):2034-P

https://doi.org/10.2337/db18-2034-P

Published: 01 July 2018

View article titled, Adipocyte-Selective Deletion of ß-Arrestin-1 in Mice Causes Adiposity, Impaired Glucose Tolerance, and Reduced Insulin Sensitivity

Journal Articles

Hepatic Muscarinic Acetylcholine Receptors Are Not Critically Involved in Maintaining Glucose Homeostasis in Mice

Jian H. Li, Dinesh Gautam, Sung-Jun Han, Jean-Marc Guettier, Yinghong Cui, Huiyan Lu, Chuxia Deng, James O'Hare, William Jou, Oksana Gavrilova, Christoph Buettner, Jürgen Wess

Diabetes 2009;58(12):2776–2787

https://doi.org/10.2337/db09-0522

Published: 14 September 2009

View article titled, Hepatic Muscarinic Acetylcholine Receptors Are Not Critically Involved in Maintaining Glucose Homeostasis in Mice

Includes: Supplementary data

NARROW

2092-LB: Receptor-Mediated G12 Signaling Strongly Promotes Insulin Secretion from Pancreatic Beta Cells

2055-LB: Temporal Resolution of Single-Cell Transcriptomics and Epigenomics of Murine Pancreatic Islet in Diet-Induced Obesity

An Intraislet Paracrine Signaling Pathway That Enables Glucagon to Stimulate Pancreatic β-Cells

Adipocyte G Protein–Coupled Receptors as Potential Targets for Novel Antidiabetic Drugs

32-OR: Receptor-Mediated Gq Signaling in Adipocytes as a Critical Modulator of Systemic Glucose and Lipid Homeostasis

1694-P: Beta-Arrestin 1 Suppresses Myogenic Reprogramming of Brown Fat to Maintain Euglycemia

2129-P: Glucagon Secretion from Pancreatic Islets Is Regulated by Beta-Arrestin-1

1971-P: Activation of Adipocyte Gq Signaling Causes Improved Whole-Body Glucose Homeostasis

38-OR: Beta-Arrestin-1 Regulates Pancreatic Beta-Cell Function and Plays a Key Role in Maintaining Whole Body Glucose Homeostasis

1781-P: Adipocyte GI Signaling Regulates Whole-Body Glucose Homeostasis and Insulin Sensitivity

1797-P: ß-arrestin-1 in AgRP Neurons Plays Crucial Role in Maintaining Whole Body Glucose Homeostasis

Skeletal Muscle–Specific Activation of G_q Signaling Maintains Glucose Homeostasis

A Positive Allosteric Modulator Enhances the Ability of Beta Cell M3 Muscarinic Receptors to Simulate Insulin Secretion In Vitro and In Vivo

Polymorphic Role of P2Y₆ Receptor in Insulin Sensitive Organs—Adipose Tissue and Skeletal Muscle

Adipocyte-Selective Deletion of ß-Arrestin-1 in Mice Causes Adiposity, Impaired Glucose Tolerance, and Reduced Insulin Sensitivity

Hepatic Muscarinic Acetylcholine Receptors Are Not Critically Involved in Maintaining Glucose Homeostasis in Mice

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