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J. Brent Richards
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Journal Articles

Connecting Genomics and Proteomics to Identify Protein Biomarkers for Adult and Youth-Onset Type 2 Diabetes: A Two-Sample Mendelian Randomization Study

Free
Faegheh Ghanbari, Nahid Yazdanpanah, Mojgan Yazdanpanah, J. Brent Richards, Despoina Manousaki
Journal: Diabetes
Diabetes 2022;71(6):1324–1337
https://doi.org/10.2337/db21-1046
Published: 02 March 2022
View articletitled, Connecting Genomics and Proteomics to Identify Protein Biomarkers for Adult and Youth-Onset Type 2 Diabetes: A Two-Sample Mendelian Randomization Study
Open the PDF for Connecting Genomics and Proteomics to Identify Protein Biomarkers for Adult and Youth-Onset Type 2 Diabetes: A Two-Sample Mendelian Randomization Study in another window
Journal Articles

Rare Genetic Variants of Large Effect Influence Risk of Type 1 Diabetes

Free
Vincenzo Forgetta, Despoina Manousaki, Roman Istomine, Stephanie Ross, Marie-Catherine Tessier, Luc Marchand, Min Li, Hui-Qi Qu, Jonathan P. Bradfield, Struan F.A. Grant, Hakon Hakonarson, the DCCT/EDIC Research Group, Andrew D. Paterson, Ciriaco Piccirillo, Constantin Polychronakos, J. Brent Richards
Journal: Diabetes
Diabetes 2020;69(4):784–795
https://doi.org/10.2337/db19-0831
Published: 31 January 2020
View articletitled, Rare Genetic Variants of Large Effect Influence Risk of Type 1 Diabetes
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Includes: Supplementary data
Journal Articles

Genetic Evidence for a Normal-Weight “Metabolically Obese” Phenotype Linking Insulin Resistance, Hypertension, Coronary Artery Disease, and Type 2 Diabetes

Free
Hanieh Yaghootkar, Robert A. Scott, Charles C. White, Weihua Zhang, Elizabeth Speliotes, Patricia B. Munroe, Georg B. Ehret, Joshua C. Bis, Caroline S. Fox, Mark Walker, Ingrid B. Borecki, Joshua W. Knowles, Laura Yerges-Armstrong, Claes Ohlsson, John R.B. Perry, John C. Chambers, Jaspal S. Kooner, Nora Franceschini, Claudia Langenberg, Marie-France Hivert, Zari Dastani, J. Brent Richards, Robert K. Semple, Timothy M. Frayling
Journal: Diabetes
Diabetes 2014;63(12):4369–4377
https://doi.org/10.2337/db14-0318
Published: 13 November 2014
View articletitled, Genetic Evidence for a Normal-Weight “Metabolically Obese” Phenotype Linking Insulin Resistance, Hypertension, Coronary Artery Disease, and Type 2 Diabetes
Open the PDF for Genetic Evidence for a Normal-Weight “Metabolically Obese” Phenotype Linking Insulin Resistance, Hypertension, Coronary Artery Disease, and Type 2 Diabetes in another window
Includes: Supplementary data
Journal Articles

Expression of Phosphofructokinase in Skeletal Muscle Is Influenced by Genetic Variation and Associated With Insulin Sensitivity

Open Access
Sarah Keildson, Joao Fadista, Claes Ladenvall, Åsa K. Hedman, Targ Elgzyri, Kerrin S. Small, Elin Grundberg, Alexandra C. Nica, Daniel Glass, J. Brent Richards, Amy Barrett, James Nisbet, Hou-Feng Zheng, Tina Rönn, Kristoffer Ström, Karl-Fredrik Eriksson, Inga Prokopenko, MAGIC Consortium, DIAGRAM Consortium, MuTHER Consortium, Timothy D. Spector, Emmanouil T. Dermitzakis, Panos Deloukas, Mark I. McCarthy, Johan Rung, Leif Groop, Paul W. Franks, Cecilia M. Lindgren, Ola Hansson
Journal: Diabetes
Diabetes 2014;63(3):1154–1165
https://doi.org/10.2337/db13-1301
Published: 13 February 2014
View articletitled, Expression of Phosphofructokinase in Skeletal Muscle Is Influenced by Genetic Variation and Associated With Insulin Sensitivity
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Includes: Supplementary data
Journal Articles

Mendelian Randomization Studies Do Not Support a Causal Role for Reduced Circulating Adiponectin Levels in Insulin Resistance and Type 2 Diabetes

Open Access
Hanieh Yaghootkar, Claudia Lamina, Robert A. Scott, Zari Dastani, Marie-France Hivert, Liling L. Warren, Alena Stancáková, Sarah G. Buxbaum, Leo-Pekka Lyytikäinen, Peter Henneman, Ying Wu, Chloe Y.Y. Cheung, James S. Pankow, Anne U. Jackson, Stefan Gustafsson, Jing Hua Zhao, Christie M. Ballantyne, Weijia Xie, Richard N. Bergman, Michael Boehnke, Fatiha el Bouazzaoui, Francis S. Collins, Sandra H. Dunn, Josee Dupuis, Nita G. Forouhi, Christopher Gillson, Andrew T. Hattersley, Jaeyoung Hong, Mika Kähönen, Johanna Kuusisto, Lyudmyla Kedenko, Florian Kronenberg, Alessandro Doria, Themistocles L. Assimes, Ele Ferrannini, Torben Hansen, Ke Hao, Hans Häring, Joshua W. Knowles, Cecilia M. Lindgren, John J. Nolan, Jussi Paananen, Oluf Pedersen, Thomas Quertermous, Ulf Smith, the GENESIS Consortium, the RISC Consortium, Terho Lehtimäki, Ching-Ti Liu, Ruth J.F. Loos, Mark I. McCarthy, Andrew D. Morris, Ramachandran S. Vasan, Tim D. Spector, Tanya M. Teslovich, Jaakko Tuomilehto, Ko Willems van Dijk, Jorma S. Viikari, Na Zhu, Claudia Langenberg, Erik Ingelsson, Robert K. Semple, Alan R. Sinaiko, Colin N.A. Palmer, Mark Walker, Karen S.L. Lam, Bernhard Paulweber, Karen L. Mohlke, Cornelia van Duijn, Olli T. Raitakari, Aurelian Bidulescu, Nick J. Wareham, Markku Laakso, Dawn M. Waterworth, Debbie A. Lawlor, James B. Meigs, J. Brent Richards, Timothy M. Frayling
Journal: Diabetes
Diabetes 2013;62(10):3589–3598
https://doi.org/10.2337/db13-0128
Published: 17 September 2013
View articletitled, Mendelian Randomization Studies Do Not Support a Causal Role for Reduced Circulating Adiponectin Levels in Insulin Resistance and Type 2 Diabetes
Open the PDF for Mendelian Randomization Studies Do Not Support a Causal Role for Reduced Circulating Adiponectin Levels in Insulin Resistance and Type 2 Diabetes in another window
Includes: Supplementary data