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Journal Articles

Peripheral Insulin Regulates a Broad Network of Gene Expression in Hypothalamus, Hippocampus, and Nucleus Accumbens

Weikang Cai, Xuemei Zhang, Thiago M. Batista, Rubén García-Martín, Samir Softic, Guoxiao Wang, Alfred K. Ramirez, Masahiro Konishi, Brian T. O’Neill, Jong Hun Kim, Jason K. Kim, C. Ronald Kahn

Diabetes 2021;70(8):1857–1873

DOI: https://doi.org/10.2337/db20-1119

Published: 24 May 2021

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Journal Articles

Muscle-Specific Insulin Receptor Overexpression Protects Mice From Diet-Induced Glucose Intolerance but Leads to Postreceptor Insulin Resistance

Guoxiao Wang, Yingying Yu, Weikang Cai, Thiago M. Batista, Sujin Suk, Hye Lim Noh, Michael Hirshman, Pasquale Nigro, Mengyao Ella Li, Samir Softic, Laurie Goodyear, Jason K. Kim, C. Ronald Kahn

Diabetes 2020;69(11):2294–2309

DOI: https://doi.org/10.2337/db20-0439

Published: 31 August 2020

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Meeting Abstracts

1727-P: Mice Deficient in Myeloid Cell-Derived Interleukin-1a Are Protected from Diet-Induced Obesity and Insulin Resistance

SUJIN SUK, RANDALL H. FRIEDLINE, HYE LIM NOH, XIAODI HU, DUY A. TRAN, LAUREN A. TAUER, ALLISON M. KIM, LAUREN H. KIM, JASON K. KIM

Diabetes 2020;69(Supplement_1):1727-P

DOI: https://doi.org/10.2337/db20-1727-P

Published: 01 June 2020

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Meeting Abstracts

1726-P: Male Mice Lacking Estrogen Receptor Beta Develop Obesity but Are Protected from Diet-Induced Insulin Resistance in Skeletal Muscle

RANDALL H. FRIEDLINE, HYE LIM NOH, SUJIN SUK, CEREN GORAL, KAREN A. DUNPHY, AMY L. ROBERTS, DUY A. TRAN, LAUREN A. TAUER, XIAODI HU, LAUREN H. KIM, ALLISON M. KIM, D. JOSEPH JERRY, JASON K. KIM

Diabetes 2020;69(Supplement_1):1726-P

DOI: https://doi.org/10.2337/db20-1726-P

Published: 01 June 2020

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Meeting Abstracts

1991-P: Mammary Tumors Increase Diet-Induced Obesity and Insulin Resistance in Female MMTV-PyMT Mice

HYE LIM NOH, HEE JOON KANG, JOSE MERCADO-MATOS, RANDALL H. FRIEDLINE, SUJIN SUK, XIAODI HU, DUY A. TRAN, LAUREN A. TAUER, MIN-JI KO, JUNGEUN CHOI, THAVANVOTEY LUONG, YURAN TSUCHIDA, LESLIE M. SHAW, JASON K. KIM

Diabetes 2019;68(Supplement_1):1991-P

DOI: https://doi.org/10.2337/db19-1991-P

Published: 01 June 2019

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Meeting Abstracts

1992-P: Early and Chronic Exposure to Penicillin Increases Obesity and Insulin Resistance in High-Fat Diet-Fed Mice

HYE LIM NOH, SUJIN SUK, RANDALL H. FRIEDLINE, XIAODI HU, DUY A. TRAN, LAUREN A. TAUER, JUNGEUN CHOI, MIN-JI KO, BRANDON KIM, TANUJ SURAPANENI, MARTIN J. BLASER, JASON K. KIM

Diabetes 2019;68(Supplement_1):1992-P

DOI: https://doi.org/10.2337/db19-1992-P

Published: 01 June 2019

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Meeting Abstracts

1805-P: Insulin Regulates a Broad Network of Gene Expression in the Brain to Regulated Brain Metabolism and Neurotransmission

WEIKANG CAI, THIAGO M. BATISTA, RUBEN GARCIA MARTIN, ALFRED RAMIREZ, MASAHIRO KONISHI, O'NEILL BRIAN T., JASON K. KIM, C. RONALD KAHN

Diabetes 2019;68(Supplement_1):1805-P

DOI: https://doi.org/10.2337/db19-1805-P

Published: 01 June 2019

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Journal Articles

Loss of Nuclear and Membrane Estrogen Receptor-α Differentially Impairs Insulin Secretion and Action in Male and Female Mice

Camille Allard, Jamie J. Morford, Beibei Xu, Benjamin Salwen, Weiwei Xu, Lucie Desmoulins, Andrea Zsombok, Jason K. Kim, Ellis R. Levin, Franck Mauvais-Jarvis

Diabetes 2019;68(3):490–501

DOI: https://doi.org/10.2337/db18-0293

Published: 10 October 2018

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Includes: Supplementary data

Meeting Abstracts

IMG-1 Reduces Blood Glucose Levels in Type 1 Diabetic Animal Models

JONATHAN B. POLLETT, HYE LIM NOH, JASON K. KIM, NGOC THAI

Diabetes 2018;67(Supplement_1):1215-P

DOI: https://doi.org/10.2337/db18-1215-P

Published: 01 July 2018

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Meeting Abstracts

IMG-1 Lowers Insulin Resistance by Decreasing Hepatic Glucose Production in a DIO Mouse Clamp Test

JONATHAN B. POLLETT, HYE LIM NOH, JASON K. KIM, NGOC THAI

Diabetes 2018;67(Supplement_1):1214-P

DOI: https://doi.org/10.2337/db18-1214-P

Published: 01 July 2018

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Meeting Abstracts

Insulin Acutely Regulates Gene Expression in Brain–A New Potential Major Level of Control of Metabolism and Neurotransmission

WEIKANG CAI, ALFRED RAMIREZ, JONATHAN DREYFUSS, THIAGO M. BATISTA, RUBEN GARCIA MARTIN, HUI PAN, MENGYAO E. LI, BRIAN T. O'NEILL, JASON K. KIM, C. RONALD KAHN

Diabetes 2018;67(Supplement_1):1792-P

DOI: https://doi.org/10.2337/db18-1792-P

Published: 01 July 2018

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Meeting Abstracts

Dissection of Insulin-Dependent Pathways in Skeletal Muscle under Physiological and Diabetic Conditions

THIAGO M. BATISTA, RUBEN GARCIA MARTIN, WEIKANG CAI, SUJIN SUK, HYE LIM NOH, JASON K. KIM, C. RONALD KAHN

Diabetes 2018;67(Supplement_1):1785-P

DOI: https://doi.org/10.2337/db18-1785-P

Published: 01 July 2018

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Meeting Abstracts

Early Life Exposure to Antibiotic Alters Energy Balance during Chronic High-Fat Feeding in Adult Male and Female Mice

HYE LIM NOH, SUJIN SUK, RANDALL H. FRIEDLINE, KUNIKAZU INASHIMA, DUY A. TRAN, ALLISON M. KIM, SOOYOUNG KIM, SANGEUN JEONG, CECILIA UONG, BERK A. OZKAN, VISHAL KASINA, KATHERINE P. KNOWLES, GUILLERMO PEREZ-PEREZ, KI WON LEE, MARTIN J. BLASER, JASON K. KIM

Diabetes 2018;67(Supplement_1):1999-P

DOI: https://doi.org/10.2337/db18-1999-P

Published: 01 July 2018

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Meeting Abstracts

DNA Repair Enzyme Ogg1 Regulates Hepatic Insulin Resistance in High-Fat Diet-Fed Obese Mice

LARYSA YUZEFOVYCH, MICHELE SCHULER, HYE LIM NOH, SUJIN SUK, JASON K. KIM, LYUDMILA RACHEK

Diabetes 2018;67(Supplement_1):235-LB

DOI: https://doi.org/10.2337/db18-235-LB

Published: 01 July 2018

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Meeting Abstracts

Grp78 Is Critical for Beta-Cell Maturation and Survival

ROHIT B. SHARMA, XIAOYING ZHENG, BRIAN GABLASKI, JASON K. KIM, AMY S. LEE, LAURA C. ALONSO

Diabetes 2018;67(Supplement_1):85-OR

DOI: https://doi.org/10.2337/db18-85-OR

Published: 01 July 2018

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Journal Articles

Dietary Betaine Supplementation Increases Fgf21 Levels to Improve Glucose Homeostasis and Reduce Hepatic Lipid Accumulation in Mice

Asma Ejaz, Laura Martinez-Guino, Allison B. Goldfine, Francesc Ribas-Aulinas, Valeria De Nigris, Sílvia Ribó, Alba Gonzalez-Franquesa, Pablo M. Garcia-Roves, Elizabeth Li, Jonathan M. Dreyfuss, Walt Gall, Jason K. Kim, Teodoro Bottiglieri, Francesc Villarroya, Robert E. Gerszten, Mary-Elizabeth Patti, Carles Lerin

Diabetes 2016;65(4):902–912

DOI: https://doi.org/10.2337/db15-1094

Published: 08 February 2016

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Includes: Supplementary data

Journal Articles

Forced Hepatic Overexpression of CEACAM1 Curtails Diet-Induced Insulin Resistance

Qusai Y. Al-Share, Anthony M. DeAngelis, Sumona Ghosh Lester, Thomas A. Bowman, Sadeesh K. Ramakrishnan, Simon L. Abdallah, Lucia Russo, Payal R. Patel, Meenakshi K. Kaw, Christian K. Raphael, Andrea Jung Kim, Garrett Heinrich, Abraham D. Lee, Jason K. Kim, Rohit N. Kulkarni, William M. Philbrick, Sonia M. Najjar

Diabetes 2015;64(8):2780–2790

DOI: https://doi.org/10.2337/db14-1772

Published: 13 May 2015

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Includes: Supplementary data

Journal Articles

RAGE Regulates the Metabolic and Inflammatory Response to High-Fat Feeding in Mice

Fei Song, Carmen Hurtado del Pozo, Rosa Rosario, Yu Shan Zou, Radha Ananthakrishnan, Xiaoyuan Xu, Payal R. Patel, Vivian M. Benoit, Shi Fang Yan, Huilin Li, Richard A. Friedman, Jason K. Kim, Ravichandran Ramasamy, Anthony W. Ferrante, Jr., Ann Marie Schmidt

Diabetes 2014;63(6):1948–1965

DOI: https://doi.org/10.2337/db13-1636

Published: 15 May 2014

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Includes: Supplementary data

Journal Articles

Response to Comment on: Kumar et al. Fat Cell–Specific Ablation of Rictor in Mice Impairs Insulin-Regulated Fat Cell and Whole-Body Glucose and Lipid Metabolism. Diabetes 2010;59:1397–1406

Anil Kumar, Susanna R. Keller, Jason K. Kim, Mark A. Magnuson, Thurl E. Harris

Diabetes 2011;60(4):e15

DOI: https://doi.org/10.2337/db11-0135

Published: 22 March 2011

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Journal Articles

Links Between Insulin Resistance, Adenosine A_2B Receptors, and Inflammatory Markers in Mice and Humans

Robert A. Figler, Guoquan Wang, Susseela Srinivasan, Dae Young Jung, Zhiyou Zhang, James S. Pankow, Katya Ravid, Bertil Fredholm, Catherine C. Hedrick, Stephen S. Rich, Jason K. Kim, Kathryn F. LaNoue, Joel Linden

Diabetes 2011;60(2):669–679

DOI: https://doi.org/10.2337/db10-1070

Published: 21 January 2011

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Includes: Supplementary data

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NARROW

Peripheral Insulin Regulates a Broad Network of Gene Expression in Hypothalamus, Hippocampus, and Nucleus Accumbens

Muscle-Specific Insulin Receptor Overexpression Protects Mice From Diet-Induced Glucose Intolerance but Leads to Postreceptor Insulin Resistance

1727-P: Mice Deficient in Myeloid Cell-Derived Interleukin-1a Are Protected from Diet-Induced Obesity and Insulin Resistance

1726-P: Male Mice Lacking Estrogen Receptor Beta Develop Obesity but Are Protected from Diet-Induced Insulin Resistance in Skeletal Muscle

1991-P: Mammary Tumors Increase Diet-Induced Obesity and Insulin Resistance in Female MMTV-PyMT Mice

1992-P: Early and Chronic Exposure to Penicillin Increases Obesity and Insulin Resistance in High-Fat Diet-Fed Mice

1805-P: Insulin Regulates a Broad Network of Gene Expression in the Brain to Regulated Brain Metabolism and Neurotransmission

Loss of Nuclear and Membrane Estrogen Receptor-α Differentially Impairs Insulin Secretion and Action in Male and Female Mice

IMG-1 Reduces Blood Glucose Levels in Type 1 Diabetic Animal Models

IMG-1 Lowers Insulin Resistance by Decreasing Hepatic Glucose Production in a DIO Mouse Clamp Test

Insulin Acutely Regulates Gene Expression in Brain–A New Potential Major Level of Control of Metabolism and Neurotransmission

Dissection of Insulin-Dependent Pathways in Skeletal Muscle under Physiological and Diabetic Conditions

Early Life Exposure to Antibiotic Alters Energy Balance during Chronic High-Fat Feeding in Adult Male and Female Mice

DNA Repair Enzyme Ogg1 Regulates Hepatic Insulin Resistance in High-Fat Diet-Fed Obese Mice

Grp78 Is Critical for Beta-Cell Maturation and Survival

Dietary Betaine Supplementation Increases Fgf21 Levels to Improve Glucose Homeostasis and Reduce Hepatic Lipid Accumulation in Mice

Forced Hepatic Overexpression of CEACAM1 Curtails Diet-Induced Insulin Resistance

RAGE Regulates the Metabolic and Inflammatory Response to High-Fat Feeding in Mice

Response to Comment on: Kumar et al. Fat Cell–Specific Ablation of Rictor in Mice Impairs Insulin-Regulated Fat Cell and Whole-Body Glucose and Lipid Metabolism. Diabetes 2010;59:1397–1406

Links Between Insulin Resistance, Adenosine A_2B Receptors, and Inflammatory Markers in Mice and Humans

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