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Jack L Leahy
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Journal Articles

Physiologic and Pharmacologic Modulation of Glucose-Dependent Insulinotropic Polypeptide (GIP) Receptor Expression in β-Cells by Peroxisome Proliferator–Activated Receptor (PPAR)-γ Signaling: Possible Mechanism for the GIP Resistance in Type 2 Diabetes

Dhananjay Gupta, Mina Peshavaria, Navjot Monga, Thomas L. Jetton, Jack L. Leahy
Journal: Diabetes
Diabetes 2010;59(6):1445–1450
https://doi.org/10.2337/db09-1655
Published: 23 March 2010
View article titled, Physiologic and Pharmacologic Modulation of Glucose-Dependent Insulinotropic Polypeptide (GIP) Receptor Expression in β-Cells by Peroxisome Proliferator–Activated Receptor (PPAR)-γ Signaling: <subtitle>Possible Mechanism for the GIP Resistance in Type 2 Diabetes</subtitle>
Open the PDF for Physiologic and Pharmacologic Modulation of Glucose-Dependent Insulinotropic Polypeptide (GIP) Receptor Expression in β-Cells by Peroxisome Proliferator–Activated Receptor (PPAR)-γ Signaling: <subtitle>Possible Mechanism for the GIP Resistance in Type 2 Diabetes</subtitle> in another window
Includes: Supplementary data
Journal Articles

Mary, Mary, Quite Contrary, How Do Your β-Cells Fail?

Jack L. Leahy
Journal: Diabetes
Diabetes 2008;57(10):2563–2564
https://doi.org/10.2337/db08-0869
Published: 01 October 2008
View article titled, Mary, Mary, Quite Contrary, How Do Your β-Cells Fail?
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Journal Articles

Peroxisome Proliferator–Activated Receptor-γ Regulates Expression of PDX-1 and NKX6.1 in INS-1 Cells

Jacob A. Moibi, Dhananjay Gupta, Thomas L. Jetton, Mina Peshavaria, Ronak Desai, Jack L. Leahy
Journal: Diabetes
Diabetes 2007;56(1):88–95
https://doi.org/10.2337/db06-0948
Published: 01 January 2007
View article titled, Peroxisome Proliferator–Activated Receptor-γ Regulates Expression of PDX-1 and NKX6.1 in INS-1 Cells
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Journal Articles

Regulation of Pancreatic β-Cell Regeneration in the Normoglycemic 60% Partial-Pancreatectomy Mouse

Mina Peshavaria, Brooke L. Larmie, James Lausier, Basanthi Satish, Aida Habibovic, Violet Roskens, Kyla LaRock, Brian Everill, Jack L. Leahy, Thomas L. Jetton
Journal: Diabetes
Diabetes 2006;55(12):3289–3298
https://doi.org/10.2337/db06-0017
Published: 01 December 2006
View article titled, Regulation of Pancreatic β-Cell Regeneration in the Normoglycemic 60% Partial-Pancreatectomy Mouse
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Journal Articles

Mechanisms of Compensatory β-Cell Growth in Insulin-Resistant Rats : Roles of Akt Kinase

Thomas L. Jetton, James Lausier, Kyla LaRock, Winifred E. Trotman, Brooke Larmie, Aida Habibovic, Mina Peshavaria, Jack L. Leahy
Journal: Diabetes
Diabetes 2005;54(8):2294–2304
https://doi.org/10.2337/diabetes.54.8.2294
Published: 01 August 2005
View article titled, Mechanisms of Compensatory β-Cell Growth in Insulin-Resistant Rats : <subtitle>Roles of Akt Kinase</subtitle>
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Journal Articles

Parallel Reduction of Pancreas Insulin Content and Insulin Secretion in 48-h Tolbutamide-Infused Normoglycemic Rats

Y A Hosokawa, Jack L Leahy
Journal: Diabetes
Diabetes 1997;46(5):808–813
https://doi.org/10.2337/diab.46.5.808
Published: 01 May 1997
View article titled, Parallel Reduction of Pancreas Insulin Content and Insulin Secretion in 48-h Tolbutamide-Infused Normoglycemic Rats
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Journal Articles

Upregulated Hexokinase Activity in Isolated Islets from Diabetic 90% Pancreatectomized Rats

Hitoshi Hosokawa, Yuka Amino Hosokawa, Jack L Leahy
Journal: Diabetes
Diabetes 1995;44(11):1328–1333
https://doi.org/10.2337/diab.44.11.1328
Published: 01 November 1995
View article titled, Upregulated Hexokinase Activity in Isolated Islets from Diabetic 90% Pancreatectomized Rats
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Journal Articles

Increased Catalytic Activity of Glucokinase in Isolated Islets From Hyperinsulinemic Rats

Chuan Chen, Lisa Bumbalo, Jack L Leahy
Journal: Diabetes
Diabetes 1994;43(5):684–689
https://doi.org/10.2337/diab.43.5.684
Published: 01 May 1994
View article titled, Increased Catalytic Activity of Glucokinase in Isolated Islets From Hyperinsulinemic Rats
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Journal Articles

Diazoxide Causes Recovery of β-Cell Glucose Responsiveness in 90% Pancreatectomized Diabetic Rats

Jack L Leahy, Lisa M Bumbalo, Chuan Chen
Journal: Diabetes
Diabetes 1994;43(2):173–179
https://doi.org/10.2337/diab.43.2.173
Published: 01 February 1994
View article titled, Diazoxide Causes Recovery of β-Cell Glucose Responsiveness in 90% Pancreatectomized Diabetic Rats
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Journal Articles

Increased Proinsulin/Insulin Ratio in Pancreas Extracts of Hyperglycemic Rats

Jack L Leahy
Journal: Diabetes
Diabetes 1993;42(1):22–27
https://doi.org/10.2337/diab.42.1.22
Published: 01 January 1993
View article titled, Increased Proinsulin/Insulin Ratio in Pancreas Extracts of Hyperglycemic Rats
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Journal Articles

Relative Hypersecretion of Proinsulin in Rat Model of NIDDM

Jack L Leahy, Phillipe A Halban, Gordon C Weir
Journal: Diabetes
Diabetes 1991;40(8):985–989
https://doi.org/10.2337/diab.40.8.985
Published: 01 August 1991
View article titled, Relative Hypersecretion of Proinsulin in Rat Model of NIDDM
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