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Meeting Abstracts

201-OR: Fasting and Postprandial Triglycerides in Early Pregnancy Correlate with Mean Glucose and Time-in-Range by CGM at 28 Weeks of Gestation

LINDA A. BARBOUR, BAILEY K. FOSDICK, EMILY Z. DUNN, STEPHANIE PIERCE, KRISTY P. ROLLOFF, ELIZABETH PHILLIPS, LAURA K. MOSS, JOCELYN PHIPERS, RODNEY K. EDWARDS, JACOB E. FRIEDMAN, TERI L. HERNANDEZ

Diabetes 2024;73(Supplement_1):201-OR

https://doi.org/10.2337/db24-201-OR

Published: 14 June 2024

View article titled, 201-OR: Fasting and Postprandial Triglycerides in Early Pregnancy Correlate with Mean Glucose and Time-in-Range by CGM at 28 Weeks of Gestation

Meeting Abstracts

1579-P: Altered Serum Ceramides as Part of Dyslipidemia in Adolescents with Metabolic Dysfunction–Associated Steatotic Liver Disease

KEVIN R. SHORT, JACOB E. FRIEDMAN, LIPING WANG, SCOTT A. SUMMERS

Diabetes 2024;73(Supplement_1):1579-P

https://doi.org/10.2337/db24-1579-P

Published: 14 June 2024

View article titled, 1579-P: Altered Serum Ceramides as Part of Dyslipidemia in Adolescents with Metabolic Dysfunction–Associated Steatotic Liver Disease

Journal Articles

A Maternal Western-Style Diet Impairs Skeletal Muscle Lipid Metabolism in Adolescent Japanese Macaques

Keenan T. Greyslak, Byron Hetrick, Bryan C. Bergman, Tyler A. Dean, Stephanie R. Wesolowski, Maureen Gannon, Simon Schenk, Elinor L. Sullivan, Kjersti M. Aagaard, Paul Kievit, Adam J. Chicco, Jacob E. Friedman, Carrie E. McCurdy

Diabetes 2023;72(12):1766–1780

https://doi.org/10.2337/db23-0289

Published: 19 September 2023

View article titled, A Maternal Western-Style Diet Impairs Skeletal Muscle Lipid Metabolism in Adolescent Japanese Macaques

Journal Articles

Metformin Disrupts Signaling and Metabolism in Fetal Hepatocytes

Karli S. Swenson, Dong Wang, Amanda K. Jones, Michael J. Nash, Rebecca O’Rourke, Diana L. Takahashi, Paul Kievit, Jon D. Hennebold, Kjersti M. Aagaard, Jacob E. Friedman, Kenneth L. Jones, Paul J. Rozance, Laura D. Brown, Stephanie R. Wesolowski

Diabetes 2023;72(9):1214–1227

https://doi.org/10.2337/db23-0089

Published: 22 June 2023

View article titled, Metformin Disrupts Signaling and Metabolism in Fetal Hepatocytes

Meeting Abstracts

48-OR: Maternal Triglycerides in Diet-Controlled GDM Correlate with Newborn Triglycerides and Infant Fat Mass at Four Months of Life

PAUL J. ROZANCE, LINDA (LYNN) A. BARBOUR, EMILY Z. DUNN, SARAH S. FARABI, NICOLE HIRSCH, KRISTY P. ROLLOFF, JACOB E. FRIEDMAN, TERI L. HERNANDEZ

Diabetes 2023;72(Supplement_1):48-OR

https://doi.org/10.2337/db23-48-OR

Published: 20 June 2023

View article titled, 48-OR: Maternal Triglycerides in Diet-Controlled GDM Correlate with Newborn Triglycerides and Infant Fat Mass at Four Months of Life

Meeting Abstracts

1173-P: Maternally Supplemented PQQ Targets Ceramide Metabolism in Offspring to Blunt Developmental Programming of NAFLD

ASHOK MANDALA, APRIL M. TEAGUE, RACHEL JANSSEN, NIKHIL PATIL, ADITYA D. JOSHI, JACOB E. FRIEDMAN, KAREN R. JONSCHER

Diabetes 2023;72(Supplement_1):1173-P

https://doi.org/10.2337/db23-1173-P

Published: 20 June 2023

View article titled, 1173-P: Maternally Supplemented PQQ Targets Ceramide Metabolism in Offspring to Blunt Developmental Programming of NAFLD

Meeting Abstracts

602-P: A Higher Complex-Carbohydrate Diet Lowers Metabolically Unfavorable Markers Associated with Gestational Diabetes Mellitus

KAMERON SUGINO, TERI L. HERNANDEZ, LINDA A. BARBOUR, JACOB E. FRIEDMAN, DANIEL FRANK

Diabetes 2023;72(Supplement_1):602-P

https://doi.org/10.2337/db23-602-P

Published: 20 June 2023

View article titled, 602-P: A Higher Complex-Carbohydrate Diet Lowers Metabolically Unfavorable Markers Associated with Gestational Diabetes Mellitus

Journal Articles

miR-130b/301b Is a Negative Regulator of Beige Adipogenesis and Energy Metabolism In Vitro and In Vivo

Wenyi Luo, Youngsil Kim, Mary Ellen Jensen, Oana Herlea-Pana, Weidong Wang, Michael C. Rudolph, Jacob E. Friedman, Steven D. Chernausek, Shaoning Jiang

Diabetes 2022;71(11):2360–2371

https://doi.org/10.2337/db22-0205

Published: 24 August 2022

View article titled, miR-130b/301b Is a Negative Regulator of Beige Adipogenesis and Energy Metabolism In Vitro and In Vivo

Meeting Abstracts

320-OR: Maternal Overnutrition Confers Increased Spare Respiratory Capacity and Glucose-Stimulated Insulin Secretion in Nonhuman Primate Offspring Islets

DARIAN T. CARROLL, JOSEPH M. ELSAKR, VALERIE F. RICCIARDI, JENNIFER C. DUNN, SARAH R. LINDSLEY, TYLER DEAN, MELISSA KIRIGITI, DIANA L. TAKAHASHI, STEPHANIE R. WESOLOWSKI, CARRIE E. MCCURDY, PAUL KIEVIT, KJERSTI M. AAGAARD, JACOB E. FRIEDMAN, MAUREEN GANNON

Diabetes 2022;71(Supplement_1):320-OR

https://doi.org/10.2337/db22-320-OR

Published: 01 June 2022

View article titled, 320-OR: Maternal Overnutrition Confers Increased Spare Respiratory Capacity and Glucose-Stimulated Insulin Secretion in Nonhuman Primate Offspring Islets

Meeting Abstracts

107-OR: Randomization to a Higher–Complex Carbohydrate or Conventional Diet in GDM Results in Equivalent Glycemic Control by Continuous Glucose Monitoring

TERI L. HERNANDEZ, EMILY Z. DUNN, NICOLE HIRSCH, KRISTY P. ROLLOFF, JOHN P. CORBETT, SARAH S. FARABI, JACOB E. FRIEDMAN, LINDA (LYNN) A. BARBOUR

Diabetes 2022;71(Supplement_1):107-OR

https://doi.org/10.2337/db22-107-OR

Published: 01 June 2022

View article titled, 107-OR: Randomization to a Higher–Complex Carbohydrate or Conventional Diet in GDM Results in Equivalent Glycemic Control by Continuous Glucose Monitoring

Journal Articles

Placental Insulin/IGF-1 Signaling, PGC-1α, and Inflammatory Pathways Are Associated With Metabolic Outcomes at 4–6 Years of Age: The ECHO Healthy Start Cohort

Madeline Rose Keleher, Kathryn Erickson, Harry A. Smith, Katerina J. Kechris, Ivana V. Yang, Dana Dabelea, Jacob E. Friedman, Kristen E. Boyle, Thomas Jansson

Diabetes 2021;70(3):745–751

https://doi.org/10.2337/db20-0902

Published: 07 January 2021

View article titled, Placental Insulin/IGF-1 Signaling, PGC-1α, and Inflammatory Pathways Are Associated With Metabolic Outcomes at 4–6 Years of Age: The ECHO Healthy Start Cohort

Meeting Abstracts

97-OR: Randomization to a Higher–Complex Carbohydrate vs. Conventional Diet in GDM Improves Glucose Tolerance and Results in Similar Cord Blood Insulin and Newborn Adiposity

TERI L. HERNANDEZ, SARAH S. FARABI, JARON ARBET, NICOLE HIRSCH, EMILY Z. DUNN, KRISTY P. HEISS, JAYNE MARTIN CARLI, NANCY F. KREBS, THERESA L. POWELL, REGINA REYNOLDS, RACHAEL E. VAN PELT, JACOB E. FRIEDMAN, LINDA (LYNN) A. BARBOUR

Diabetes 2020;69(Supplement_1):97-OR

https://doi.org/10.2337/db20-97-OR

Published: 01 June 2020

View article titled, 97-OR: Randomization to a Higher–Complex Carbohydrate vs. Conventional Diet in GDM Improves Glucose Tolerance and Results in Similar Cord Blood Insulin and Newborn Adiposity

Meeting Abstracts

1855-P: Early Life Dysbiosis in Offspring of Obese Mice Promotes Hepatic Macrophage Dysfunction

KAREN R. JONSCHER, RACHEL JANSSEN, SUSAN KOVATS, RACHEL MCMAHAN, JACOB E. FRIEDMAN

Diabetes 2020;69(Supplement_1):1855-P

https://doi.org/10.2337/db20-1855-P

Published: 01 June 2020

View article titled, 1855-P: Early Life Dysbiosis in Offspring of Obese Mice Promotes Hepatic Macrophage Dysfunction

Journal Articles

Maternal Obesity and Western-Style Diet Impair Fetal and Juvenile Offspring Skeletal Muscle Insulin-Stimulated Glucose Transport in Nonhuman Primates

William Campodonico-Burnett, Byron Hetrick, Stephanie R. Wesolowski, Simon Schenk, Diana L. Takahashi, Tyler A. Dean, Elinor L. Sullivan, Paul Kievit, Maureen Gannon, Kjersti Aagaard, Jacob E. Friedman, Carrie E. McCurdy

Diabetes 2020;69(7):1389–1400

https://doi.org/10.2337/db19-1218

Published: 30 April 2020

View article titled, Maternal Obesity and Western-Style Diet Impair Fetal and Juvenile Offspring Skeletal Muscle Insulin-Stimulated Glucose Transport in Nonhuman Primates

Meeting Abstracts

352-OR: Maternal Triglycerides in Gestational Diabetes Are Strongly Associated with Increased Newborn Hepatic Fat Independent of Subcutaneous Fat

TERI L. HERNANDEZ, SARAH S. FARABI, NICOLE HIRSCH, EMILY Z. DUNN, ELIZABETH A. HAUGEN, DAVID BRUMBAUGH, MARK S. BROWN, JACOB E. FRIEDMAN, LINDA (LYNN) A. BARBOUR

Diabetes 2019;68(Supplement_1):352-OR

https://doi.org/10.2337/db19-352-OR

Published: 01 June 2019

View article titled, 352-OR: Maternal Triglycerides in Gestational Diabetes Are Strongly Associated with Increased Newborn Hepatic Fat Independent of Subcutaneous Fat

Meeting Abstracts

182-OR: Maternal Glucose and Insulin Are Associated with Lipid Metabolism and Adipogenesis Pathways in Human Umbilical Cord-Derived Mesenchymal Stem Cells: The Healthy Start Echo Cohort

MADELINE KELEHER, DANA DABELEA, JACOB E. FRIEDMAN, KRISTEN E. BOYLE

Diabetes 2019;68(Supplement_1):182-OR

https://doi.org/10.2337/db19-182-OR

Published: 01 June 2019

View article titled, 182-OR: Maternal Glucose and Insulin Are Associated with Lipid Metabolism and Adipogenesis Pathways in Human Umbilical Cord-Derived Mesenchymal Stem Cells: The Healthy Start Echo Cohort

Journal Articles

Developmental Programming of Obesity and Diabetes in Mouse, Monkey, and Man in 2018: Where Are We Headed?

Jacob E. Friedman

Diabetes 2018;67(11):2137–2151

https://doi.org/10.2337/dbi17-0011

Published: 11 October 2018

View article titled, Developmental Programming of Obesity and Diabetes in Mouse, Monkey, and Man in 2018: Where Are We Headed?

Meeting Abstracts

Maternal High-Fat Diet Persistently Alters Bone Marrow Immune Cell Proportions and Function in a Nonhuman Primate Model

MICHAEL J. NASH, TAYLOR K. SODERBORG, RACHEL C. JANSSEN, ERIC M. PIETRAS, JACOB E. FRIEDMAN

Diabetes 2018;67(Supplement_1):222-OR

https://doi.org/10.2337/db18-222-OR

Published: 01 July 2018

View article titled, Maternal High-Fat Diet Persistently Alters Bone Marrow Immune Cell Proportions and Function in a Nonhuman Primate Model

Journal Articles

Low Neonatal Plasma n-6/n-3 PUFA Ratios Regulate Offspring Adipogenic Potential and Condition Adult Obesity Resistance

Michael C. Rudolph, Matthew R. Jackman, David M. Presby, Julie A. Houck, Patricia G. Webb, Ginger C. Johnson, Taylor K. Soderborg, Becky A. de la Houssaye, Ivana V. Yang, Jacob E. Friedman, Paul S. MacLean

Diabetes 2018;67(4):651–661

https://doi.org/10.2337/db17-0890

Published: 14 November 2017

View article titled, Low Neonatal Plasma n-6/n-3 PUFA Ratios Regulate Offspring Adipogenic Potential and Condition Adult Obesity Resistance

Includes: Supplementary data

Journal Articles

Mesenchymal Stem Cells From Infants Born to Obese Mothers Exhibit Greater Potential for Adipogenesis: The Healthy Start BabyBUMP Project

Kristen E. Boyle, Zachary W. Patinkin, Allison L.B. Shapiro, Peter R. Baker, II, Dana Dabelea, Jacob E. Friedman

Diabetes 2016;65(3):647–659

https://doi.org/10.2337/db15-0849

Published: 02 December 2015

View article titled, Mesenchymal Stem Cells From Infants Born to Obese Mothers Exhibit Greater Potential for Adipogenesis: The Healthy Start BabyBUMP Project

Includes: Supplementary data

NARROW

201-OR: Fasting and Postprandial Triglycerides in Early Pregnancy Correlate with Mean Glucose and Time-in-Range by CGM at 28 Weeks of Gestation

1579-P: Altered Serum Ceramides as Part of Dyslipidemia in Adolescents with Metabolic Dysfunction–Associated Steatotic Liver Disease

A Maternal Western-Style Diet Impairs Skeletal Muscle Lipid Metabolism in Adolescent Japanese Macaques

Metformin Disrupts Signaling and Metabolism in Fetal Hepatocytes

48-OR: Maternal Triglycerides in Diet-Controlled GDM Correlate with Newborn Triglycerides and Infant Fat Mass at Four Months of Life

1173-P: Maternally Supplemented PQQ Targets Ceramide Metabolism in Offspring to Blunt Developmental Programming of NAFLD

602-P: A Higher Complex-Carbohydrate Diet Lowers Metabolically Unfavorable Markers Associated with Gestational Diabetes Mellitus

miR-130b/301b Is a Negative Regulator of Beige Adipogenesis and Energy Metabolism In Vitro and In Vivo

320-OR: Maternal Overnutrition Confers Increased Spare Respiratory Capacity and Glucose-Stimulated Insulin Secretion in Nonhuman Primate Offspring Islets

107-OR: Randomization to a Higher–Complex Carbohydrate or Conventional Diet in GDM Results in Equivalent Glycemic Control by Continuous Glucose Monitoring

Placental Insulin/IGF-1 Signaling, PGC-1α, and Inflammatory Pathways Are Associated With Metabolic Outcomes at 4–6 Years of Age: The ECHO Healthy Start Cohort

97-OR: Randomization to a Higher–Complex Carbohydrate vs. Conventional Diet in GDM Improves Glucose Tolerance and Results in Similar Cord Blood Insulin and Newborn Adiposity

1855-P: Early Life Dysbiosis in Offspring of Obese Mice Promotes Hepatic Macrophage Dysfunction

Maternal Obesity and Western-Style Diet Impair Fetal and Juvenile Offspring Skeletal Muscle Insulin-Stimulated Glucose Transport in Nonhuman Primates

352-OR: Maternal Triglycerides in Gestational Diabetes Are Strongly Associated with Increased Newborn Hepatic Fat Independent of Subcutaneous Fat

182-OR: Maternal Glucose and Insulin Are Associated with Lipid Metabolism and Adipogenesis Pathways in Human Umbilical Cord-Derived Mesenchymal Stem Cells: The Healthy Start Echo Cohort

Developmental Programming of Obesity and Diabetes in Mouse, Monkey, and Man in 2018: Where Are We Headed?

Maternal High-Fat Diet Persistently Alters Bone Marrow Immune Cell Proportions and Function in a Nonhuman Primate Model

Low Neonatal Plasma n-6/n-3 PUFA Ratios Regulate Offspring Adipogenic Potential and Condition Adult Obesity Resistance

Mesenchymal Stem Cells From Infants Born to Obese Mothers Exhibit Greater Potential for Adipogenesis: The Healthy Start BabyBUMP Project

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