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Jaswinder K. Sethi
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Journal Articles

Adaptive Changes of the Insig1/SREBP1/SCD1 Set Point Help Adipose Tissue to Cope With Increased Storage Demands of Obesity

Stefania Carobbio, Rachel M. Hagen, Christopher J. Lelliott, Marc Slawik, Gema Medina-Gomez, Chong-Yew Tan, Audrey Sicard, Helen J. Atherton, Nuria Barbarroja, Mikael Bjursell, Mohammad Bohlooly-Y, Sam Virtue, Antoinette Tuthill, Etienne Lefai, Martine Laville, Tingting Wu, Robert V. Considine, Hubert Vidal, Dominique Langin, Matej Oresic, Francisco J. Tinahones, Jose Manuel Fernandez-Real, Julian L. Griffin, Jaswinder K. Sethi, Miguel López, Antonio Vidal-Puig
Journal: Diabetes
Diabetes 2013;62(11):3697–3708
https://doi.org/10.2337/db12-1748
Published: 18 October 2013
View articletitled, Adaptive Changes of the Insig1/SREBP1/SCD1 Set Point Help Adipose Tissue to Cope With Increased Storage Demands of Obesity
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Includes: Supplementary data
Journal Articles

A New Role for Lipocalin Prostaglandin D Synthase in the Regulation of Brown Adipose Tissue Substrate Utilization

Sam Virtue, Helena Feldmann, Mark Christian, Chong Yew Tan, Mojgan Masoodi, Martin Dale, Chris Lelliott, Keith Burling, Mark Campbell, Naomi Eguchi, Peter Voshol, Jaswinder K. Sethi, Malcolm Parker, Yoshihiro Urade, Julian L. Griffin, Barbara Cannon, Antonio Vidal-Puig
Journal: Diabetes
Diabetes 2012;61(12):3139–3147
https://doi.org/10.2337/db12-0015
Published: 15 November 2012
View articletitled, A New Role for Lipocalin Prostaglandin D Synthase in the Regulation of Brown Adipose Tissue Substrate Utilization
Open the PDF for A New Role for Lipocalin Prostaglandin D Synthase in the Regulation of Brown Adipose Tissue Substrate Utilization in another window
Includes: Supplementary data
Journal Articles

Increasing Circulating IGFBP1 Levels Improves Insulin Sensitivity, Promotes Nitric Oxide Production, Lowers Blood Pressure, and Protects Against Atherosclerosis

Adil Rajwani, Vivienne Ezzat, Jessica Smith, Nadira Y. Yuldasheva, Edward R. Duncan, Matthew Gage, Richard M. Cubbon, Matthew B. Kahn, Helen Imrie, Afroze Abbas, Hema Viswambharan, Amir Aziz, Piruthivi Sukumar, Antonio Vidal-Puig, Jaswinder K. Sethi, Shouhong Xuan, Ajay M. Shah, Peter J. Grant, Karen E. Porter, Mark T. Kearney, Stephen B. Wheatcroft
Journal: Diabetes
Diabetes 2012;61(4):915–924
https://doi.org/10.2337/db11-0963
Published: 14 March 2012
View articletitled, Increasing Circulating IGFBP1 Levels Improves Insulin Sensitivity, Promotes Nitric Oxide Production, Lowers Blood Pressure, and Protects Against Atherosclerosis
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Journal Articles

Differential Lipid Partitioning Between Adipocytes and Tissue Macrophages Modulates Macrophage Lipotoxicity and M2/M1 Polarization in Obese Mice

Xavier Prieur, Crystal Y.L. Mok, Vidya R. Velagapudi, Vanessa Núñez, Lucía Fuentes, David Montaner, Ko Ishikawa, Alberto Camacho, Nuria Barbarroja, Stephen O’Rahilly, Jaswinder K. Sethi, Joaquin Dopazo, Matej Orešič, Mercedes Ricote, Antonio Vidal-Puig
Journal: Diabetes
Diabetes 2011;60(3):797–809
https://doi.org/10.2337/db10-0705
Published: 21 February 2011
View articletitled, Differential Lipid Partitioning Between Adipocytes and Tissue Macrophages Modulates Macrophage Lipotoxicity and M2/M1 Polarization in Obese Mice
Open the PDF for Differential Lipid Partitioning Between Adipocytes and Tissue Macrophages Modulates Macrophage Lipotoxicity and M2/M1 Polarization in Obese Mice in another window
Includes: Supplementary data
Journal Articles

Activatin' Human Adipose Progenitors in Obesity

Jaswinder K. Sethi
Journal: Diabetes
Diabetes 2010;59(10):2354–2357
https://doi.org/10.2337/db10-0923
Published: 01 October 2010
View articletitled, Activatin' Human Adipose Progenitors in Obesity
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Journal Articles

11β-Hydroxysteroid Dehydrogenase Type 1 Regulates Glucocorticoid-Induced Insulin Resistance in Skeletal Muscle

Stuart A. Morgan, Mark Sherlock, Laura L. Gathercole, Gareth G. Lavery, Carol Lenaghan, Iwona J. Bujalska, David Laber, Alice Yu, Gemma Convey, Rachel Mayers, Krisztina Hegyi, Jaswinder K. Sethi, Paul M. Stewart, David M. Smith, Jeremy W. Tomlinson
Journal: Diabetes
Diabetes 2009;58(11):2506–2515
https://doi.org/10.2337/db09-0525
Published: 12 August 2009
View articletitled, 11β-Hydroxysteroid Dehydrogenase Type 1 Regulates Glucocorticoid-Induced Insulin Resistance in Skeletal Muscle
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Journal Articles

Dact1, a Nutritionally Regulated Preadipocyte Gene, Controls Adipogenesis by Coordinating the Wnt/β-Catenin Signaling Network

Claire Lagathu, Constantinos Christodoulides, Sam Virtue, William P. Cawthorn, Chiara Franzin, Wendy A. Kimber, Edoardo Dalla Nora, Mark Campbell, Gema Medina-Gomez, Benjamin N.R. Cheyette, Antonio J. Vidal-Puig, Jaswinder K. Sethi
Journal: Diabetes
Diabetes 2009;58(3):609–619
https://doi.org/10.2337/db08-1180
Published: 01 March 2009
View articletitled, Dact1, a Nutritionally Regulated Preadipocyte Gene, Controls Adipogenesis by Coordinating the Wnt/β-Catenin Signaling Network
Open the PDF for Dact1, a Nutritionally Regulated Preadipocyte Gene, Controls Adipogenesis by Coordinating the Wnt/β-Catenin Signaling Network in another window
Includes: Supplementary data
Journal Articles

Pharmacological Inhibition of Glucosylceramide Synthase Enhances Insulin Sensitivity

Johannes M. Aerts, Roelof Ottenhoff, Andrew S. Powlson, Aldo Grefhorst, Marco van Eijk, Peter F. Dubbelhuis, Jan Aten, Folkert Kuipers, Mireille J. Serlie, Tom Wennekes, Jaswinder K. Sethi, Stephen O'Rahilly, Hermen S. Overkleeft
Journal: Diabetes
Diabetes 2007;56(5):1341–1349
https://doi.org/10.2337/db06-1619
Published: 01 May 2007
View articletitled, Pharmacological Inhibition of Glucosylceramide Synthase Enhances Insulin Sensitivity
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Includes: Supplementary data
Journal Articles

IGF-Binding Protein-2 Protects Against the Development of Obesity and Insulin Resistance

Stephen B. Wheatcroft, Mark T. Kearney, Ajay M. Shah, Vivienne A. Ezzat, John R. Miell, Michael Modo, Stephen C.R. Williams, Will P. Cawthorn, Gema Medina-Gomez, Antonio Vidal-Puig, Jaswinder K. Sethi, Paul A. Crossey
Journal: Diabetes
Diabetes 2007;56(2):285–294
https://doi.org/10.2337/db06-0436
Published: 01 February 2007
View articletitled, IGF-Binding Protein-2 Protects Against the Development of Obesity and Insulin Resistance
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Journal Articles

The Link Between Nutritional Status and Insulin Sensitivity Is Dependent on the Adipocyte-Specific Peroxisome Proliferator–Activated Receptor-γ2 Isoform

Gema Medina-Gomez, Sam Virtue, Christopher Lelliott, Romina Boiani, Mark Campbell, Constantinos Christodoulides, Christophe Perrin, Mercedes Jimenez-Linan, Margaret Blount, John Dixon, Dirk Zahn, Rosemary R. Thresher, Sam Aparicio, Mark Carlton, William H. Colledge, Mikko I. Kettunen, Tuulikki Seppänen-Laakso, Jaswinder K. Sethi, Stephen O’Rahilly, Kevin Brindle, Saverio Cinti, Matej Orešič, Remy Burcelin, Antonio Vidal-Puig
Journal: Diabetes
Diabetes 2005;54(6):1706–1716
https://doi.org/10.2337/diabetes.54.6.1706
Published: 01 June 2005
View articletitled, The Link Between Nutritional Status and Insulin Sensitivity Is Dependent on the Adipocyte-Specific Peroxisome Proliferator–Activated Receptor-γ2 Isoform
Open the PDF for The Link Between Nutritional Status and Insulin Sensitivity Is Dependent on the Adipocyte-Specific Peroxisome Proliferator–Activated Receptor-γ2 Isoform in another window
Includes: Supplementary data