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Meeting Abstracts

471-P: Anti-NFKB Inhibitor Beta Antibody Correlates with Cardiovascular Disease in Type 1 Diabetic Patients with Autoimmune Disease

KYOUNGMIN PARK, LINDA PHAM, QIAN LI, MARC GREGORY YU, JIALIN FU, SURYA VISHVA TEJA JANGOLLA, I-HSIEN WU, GEORGE L. KING

Diabetes 2024;73(Supplement_1):471-P

https://doi.org/10.2337/db24-471-P

Published: 14 June 2024

View article titled, 471-P: Anti-NFKB Inhibitor Beta Antibody Correlates with Cardiovascular Disease in Type 1 Diabetic Patients with Autoimmune Disease

Meeting Abstracts

320-OR: Pyruvate Kinase M2 (PKM2) Activation in the Podocyte Prevented Subset Differentiation of Glomerular Cells Induced by Diabetes

JIALIN FU, QIAN LI, KYOUNGMIN PARK, TAKANORI SHINJO, QIAN HUANG, I-HSIEN WU, GEORGE L. KING

Diabetes 2024;73(Supplement_1):320-OR

https://doi.org/10.2337/db24-320-OR

Published: 14 June 2024

View article titled, 320-OR: Pyruvate Kinase M2 (PKM2) Activation in the Podocyte Prevented Subset Differentiation of Glomerular Cells Induced by Diabetes

Meeting Abstracts

404-P: Single-Cell RNA Profiling Changes in Glomerular Cells in Diabetic Nephropathy (DN)

JIALIN FU, QIAN LI, KYOUNGMIN PARK, QIAN HUANG, I-HSIEN WU, GEORGE L. KING

Diabetes 2023;72(Supplement_1):404-P

https://doi.org/10.2337/db23-404-P

Published: 20 June 2023

View article titled, 404-P: Single-Cell RNA Profiling Changes in Glomerular Cells in Diabetic Nephropathy (DN)

Meeting Abstracts

40-OR: Insulin Stabilized Arterial Plaque by Regulating Vascular Smooth Muscle Cell Metabolism and Differentiation

QIAN LI, JIALIN FU, KYOUNGMIN PARK, I-HSIEN WU, GEORGE L. KING

Diabetes 2023;72(Supplement_1):40-OR

https://doi.org/10.2337/db23-40-OR

Published: 20 June 2023

View article titled, 40-OR: Insulin Stabilized Arterial Plaque by Regulating Vascular Smooth Muscle Cell Metabolism and Differentiation

Journal Articles

Dysregulation of CXCL1 Expression and Neutrophil Recruitment in Insulin Resistance and Diabetes-Related Periodontitis in Male Mice

Takanori Shinjo, Satoru Onizuka, Yumi Zaitsu, Atsushi Ishikado, Kyoungmin Park, Qian Li, Hisashi Yokomizo, Tatsuro Zeze, Kohei Sato, Ronald St-Louis, Jialin Fu, Wu I-Hsien, Koji Mizutani, Hatice Hasturk, Thomas E. Van Dyke, Fusanori Nishimura, George L. King

Diabetes 2023;72(7):986–998

https://doi.org/10.2337/db22-1014

Published: 14 April 2023

View article titled, Dysregulation of CXCL1 Expression and Neutrophil Recruitment in Insulin Resistance and Diabetes-Related Periodontitis in Male Mice

Meeting Abstracts

24-OR: Podocyte Targeted Pyruvate Kinase M2 (PKM2) Activation Normalized Glomerular VEGF Expression, Mitochondrial Function, Fuel Metabolism, and Diabetic Nephropathy

JIALIN FU, TAKANORI SHINJO, QIAN LI, KYOUNGMIN PARK, MARC GREGORY YU, HISASHI YOKOMIZO, QIAN HUANG, I-HSIEN WU, GEORGE L. KING

Diabetes 2022;71(Supplement_1):24-OR

https://doi.org/10.2337/db22-24-OR

Published: 01 June 2022

View article titled, 24-OR: Podocyte Targeted Pyruvate Kinase M2 (PKM2) Activation Normalized Glomerular VEGF Expression, Mitochondrial Function, Fuel Metabolism, and Diabetic Nephropathy

Meeting Abstracts

46-OR: Differential Effects of RBP3 and Anti-VEGF on Retinal Dysfunctions in Diabetic Retinopathy

QIN LI, SATORU ONIZUKA, KYOUNGMIN PARK, HYUNSEOK PARK, QIAN LI, WARD FICKWEILER, JIALIN FU, I-HSIEN WU, GEORGE L. KING

Diabetes 2022;71(Supplement_1):46-OR

https://doi.org/10.2337/db22-46-OR

Published: 01 June 2022

View article titled, 46-OR: Differential Effects of RBP3 and Anti-VEGF on Retinal Dysfunctions in Diabetic Retinopathy

Meeting Abstracts

1482-PUB: Insulin Receptors in Vascular Smooth Muscle Cells Regulate Plaque Stability by Its actions on Glycolysis and Oxidative Phosphorylation

QIAN LI, JIALIN FU, KYOUNGMIN PARK, QIN LI, GEORGE L. KING

Diabetes 2022;71(Supplement_1):1482-PUB

https://doi.org/10.2337/db22-1482-PUB

Published: 01 June 2022

View article titled, 1482-PUB: Insulin Receptors in Vascular Smooth Muscle Cells Regulate Plaque Stability by Its actions on Glycolysis and Oxidative Phosphorylation

Meeting Abstracts

55-OR: Targeted Deletion of Insulin Receptor in Vascular Smooth Muscle Cells Promoted Atherosclerosis and Unstable Plaque

QIAN LI, JIALIN FU, KYOUNGMIN PARK, I-HSIEN WU, GEORGE L. KING

Diabetes 2021;70(Supplement_1):55-OR

https://doi.org/10.2337/db21-55-OR

Published: 01 June 2021

View article titled, 55-OR: Targeted Deletion of Insulin Receptor in Vascular Smooth Muscle Cells Promoted Atherosclerosis and Unstable Plaque

Meeting Abstracts

54-OR: Nucleolin Autoantibody Accelerates Atherosclerosis in Type 1 Diabetes

KYOUNGMIN PARK, QIAN LI, HYUNSEOK PARK, JIALIN FU, STEPHAN KISSLER, ERNESTO MADDALONI, I-HSIEN WU, ANDREW H. LICHTMAN, GEORGE L. KING

Diabetes 2021;70(Supplement_1):54-OR

https://doi.org/10.2337/db21-54-OR

Published: 01 June 2021

View article titled, 54-OR: Nucleolin Autoantibody Accelerates Atherosclerosis in Type 1 Diabetes

Meeting Abstracts

183-OR: Pyruvate Kinase M2 (PKM2) Enzymatic Activity Is Necessary to Improve Podocyte Mitochondrial Function and Glomerular Fuel Metabolism and Diabetic Nephropathy

JIALIN FU, TAKANORI SHINJO, QIAN LI, RONALD ST-LOUIS, KYOUNGMIN PARK, HISASHI YOKOMIZO, MARC GREGORY YU, HETAL SHAH, I-HSIEN WU, GEORGE L. KING

Diabetes 2021;70(Supplement_1):183-OR

https://doi.org/10.2337/db21-183-OR

Published: 01 June 2021

View article titled, 183-OR: Pyruvate Kinase M2 (PKM2) Enzymatic Activity Is Necessary to Improve Podocyte Mitochondrial Function and Glomerular Fuel Metabolism and Diabetic Nephropathy

Meeting Abstracts

307-OR: Activation of Mitochondrial Activities by Pyruvate Kinase M2 (PKM2) in Podocytes Improved Glomerular Metabolism and Diabetic Nephropathy

JIALIN FU, TAKANORI SHINJO, RONALD ST-LOUIS, QIAN LI, KYOUNGMIN PARK, HISASHI YOKOMIZO, YUMI ZAITSU, MARC GREGORY YU, I-HSIEN WU, HETAL SHAH, GEORGE L. KING

Diabetes 2020;69(Supplement_1):307-OR

https://doi.org/10.2337/db20-307-OR

Published: 01 June 2020

View article titled, 307-OR: Activation of Mitochondrial Activities by Pyruvate Kinase M2 (PKM2) in Podocytes Improved Glomerular Metabolism and Diabetic Nephropathy

Meeting Abstracts

456-P: Targeted Deletion of Insulin Receptor in Vascular Smooth Muscle Cells Accelerated Thinning of Plaque Cap and Apoptosis and Atherosclerosis

QIAN LI, JIALIN FU, KYOUNGMIN PARK, YUMI ZAITSU, RONALD ST-LOUIS, CHRISTIAN RASK-MADSEN, GEORGE L. KING

Diabetes 2020;69(Supplement_1):456-P

https://doi.org/10.2337/db20-456-P

Published: 01 June 2020

View article titled, 456-P: Targeted Deletion of Insulin Receptor in Vascular Smooth Muscle Cells Accelerated Thinning of Plaque Cap and Apoptosis and Atherosclerosis

Meeting Abstracts

436-P: Characterization of Autoimmunity in the Acceleration of Atherosclerosis in Type 1 Diabetes

KYOUNGMIN PARK, QIAN LI, HYUNSEOK PARK, RONALD ST-LOUIS, JIALIN FU, CHRISTIAN RASK-MADSEN, ERNESTO MADDALONI, HISASHI YOKOMIZO, STEPHAN KISSLER, ANDREW H. LICHTMAN, GEORGE L. KING

Diabetes 2020;69(Supplement_1):436-P

https://doi.org/10.2337/db20-436-P

Published: 01 June 2020

View article titled, 436-P: Characterization of Autoimmunity in the Acceleration of Atherosclerosis in Type 1 Diabetes

Meeting Abstracts

480-P: Reversal of Diabetic Nephropathy in T2D db/db Mouse Model by Systemic Pyruvate Kinase M2 (PKM2) Activation

RONALD ST-LOUIS, JIALIN FU, KYOUNGMIN PARK, TAKANORI SHINJO, JOHANNA LUDEKE, HISASHI YOKOMIZO, QIAN LI, EMILY WOLFSON, GEORGE L. KING

Diabetes 2020;69(Supplement_1):480-P

https://doi.org/10.2337/db20-480-P

Published: 01 June 2020

View article titled, 480-P: Reversal of Diabetic Nephropathy in T2D db/db Mouse Model by Systemic Pyruvate Kinase M2 (PKM2) Activation

Meeting Abstracts

231-OR: ADA Presidents' Select Abstract: Pyruvate Kinase M2 Overexpression in Podocytes Ameliorates Nephropathy in Diabetic Mice

TAKANORI SHINJO, RONALD ST-LOUIS, JIALIN FU, KYOUNGMIN PARK, QIAN LI, HISASHI YOKOMIZO, MARC GREGORY YU, HAIYAN WANG, AIMO KANNT, THORSTEN SADOWSKI, GEORGE L. KING

Diabetes 2019;68(Supplement_1):231-OR

https://doi.org/10.2337/db19-231-OR

Published: 01 June 2019

View article titled, 231-OR: ADA Presidents' Select Abstract: Pyruvate Kinase M2 Overexpression in Podocytes Ameliorates Nephropathy in Diabetic Mice

Meeting Abstracts

628-P: Insulin's Regulation of CXCL1 Expression Is Critical for Neutrophil Recruitments and the Development of Periodontitis and Poor Wound Healing in Diabetes

TAKANORI SHINJO, QIAN LI, ATSUSHI ISHIKADO, KYOUNGMIN PARK, RONALD ST-LOUIS, HISASHI YOKOMIZO, JIALIN FU, MARC GREGORY YU, HAIYAN WANG, HATICE HASTURK, THOMAS E. VAN DYKE, GEORGE L. KING

Diabetes 2019;68(Supplement_1):628-P

https://doi.org/10.2337/db19-628-P

Published: 01 June 2019

View article titled, 628-P: Insulin's Regulation of CXCL1 Expression Is Critical for Neutrophil Recruitments and the Development of Periodontitis and Poor Wound Healing in Diabetes

Meeting Abstracts

478-P: Accelerating Atherosclerosis by Autoimmune Process in Nonobese Diabetic Mice Made ApoE Deficient by CRISPR/Cas9 Gene Editing

KYOUNGMIN PARK, QIAN LI, HAIYAN WANG, RONALD ST-LOUIS, HISASHI YOKOMIZO, ERNESTO MADDALONI, TAKANORI SHINJO, JIALIN FU, I-HSIEN WU, STEPHAN KISSLER, GEORGE L. KING

Diabetes 2019;68(Supplement_1):478-P

https://doi.org/10.2337/db19-478-P

Published: 01 June 2019

View article titled, 478-P: Accelerating Atherosclerosis by Autoimmune Process in Nonobese Diabetic Mice Made ApoE Deficient by CRISPR/Cas9 Gene Editing

Meeting Abstracts

Endothelial/Nitric Oxide Regulation of Brown Adipose Tissue Activating Lipokine, 12, 13-diHOME and Its Antiatherogenic Actions

KYOUNGMIN PARK, QIAN LI, MATT LYNES, HISASHI YOKOMIZO, TAKANORI SHINJO, RONALD ST-LOUIS, JIALIN FU, CHRISTIAN RASK-MADSEN, YU-HUA TSENG, GEORGE L. KING

Diabetes 2018;67(Supplement_1):286-OR

https://doi.org/10.2337/db18-286-OR

Published: 01 July 2018

View article titled, Endothelial/Nitric Oxide Regulation of Brown Adipose Tissue Activating Lipokine, 12, 13-diHOME and Its Antiatherogenic Actions

Meeting Abstracts

Loss of Insulin Actions on Arterial Smooth Muscle Cells May Enhance Unstable Atherosclerotic Plaque Formation

QIAN LI, JIALIN FU, KYOUNGMIN PARK, RASK-MADSEN CHRISTIAN, GEORGE L. KING

Diabetes 2018;67(Supplement_1):288-OR

https://doi.org/10.2337/db18-288-OR

Published: 01 July 2018

View article titled, Loss of Insulin Actions on Arterial Smooth Muscle Cells May Enhance Unstable Atherosclerotic Plaque Formation

NARROW

471-P: Anti-NFKB Inhibitor Beta Antibody Correlates with Cardiovascular Disease in Type 1 Diabetic Patients with Autoimmune Disease

320-OR: Pyruvate Kinase M2 (PKM2) Activation in the Podocyte Prevented Subset Differentiation of Glomerular Cells Induced by Diabetes

404-P: Single-Cell RNA Profiling Changes in Glomerular Cells in Diabetic Nephropathy (DN)

40-OR: Insulin Stabilized Arterial Plaque by Regulating Vascular Smooth Muscle Cell Metabolism and Differentiation

Dysregulation of CXCL1 Expression and Neutrophil Recruitment in Insulin Resistance and Diabetes-Related Periodontitis in Male Mice

24-OR: Podocyte Targeted Pyruvate Kinase M2 (PKM2) Activation Normalized Glomerular VEGF Expression, Mitochondrial Function, Fuel Metabolism, and Diabetic Nephropathy

46-OR: Differential Effects of RBP3 and Anti-VEGF on Retinal Dysfunctions in Diabetic Retinopathy

1482-PUB: Insulin Receptors in Vascular Smooth Muscle Cells Regulate Plaque Stability by Its actions on Glycolysis and Oxidative Phosphorylation

55-OR: Targeted Deletion of Insulin Receptor in Vascular Smooth Muscle Cells Promoted Atherosclerosis and Unstable Plaque

54-OR: Nucleolin Autoantibody Accelerates Atherosclerosis in Type 1 Diabetes

183-OR: Pyruvate Kinase M2 (PKM2) Enzymatic Activity Is Necessary to Improve Podocyte Mitochondrial Function and Glomerular Fuel Metabolism and Diabetic Nephropathy

307-OR: Activation of Mitochondrial Activities by Pyruvate Kinase M2 (PKM2) in Podocytes Improved Glomerular Metabolism and Diabetic Nephropathy

456-P: Targeted Deletion of Insulin Receptor in Vascular Smooth Muscle Cells Accelerated Thinning of Plaque Cap and Apoptosis and Atherosclerosis

436-P: Characterization of Autoimmunity in the Acceleration of Atherosclerosis in Type 1 Diabetes

480-P: Reversal of Diabetic Nephropathy in T2D db/db Mouse Model by Systemic Pyruvate Kinase M2 (PKM2) Activation

231-OR: ADA Presidents' Select Abstract: Pyruvate Kinase M2 Overexpression in Podocytes Ameliorates Nephropathy in Diabetic Mice

628-P: Insulin's Regulation of CXCL1 Expression Is Critical for Neutrophil Recruitments and the Development of Periodontitis and Poor Wound Healing in Diabetes

478-P: Accelerating Atherosclerosis by Autoimmune Process in Nonobese Diabetic Mice Made ApoE Deficient by CRISPR/Cas9 Gene Editing

Endothelial/Nitric Oxide Regulation of Brown Adipose Tissue Activating Lipokine, 12, 13-diHOME and Its Antiatherogenic Actions

Loss of Insulin Actions on Arterial Smooth Muscle Cells May Enhance Unstable Atherosclerotic Plaque Formation

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