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Meeting Abstracts

2013-LB: Population-Scale Skeletal Muscle Single-Nucleus Multiomic Profiling Reveals Extensive Context-Specific Genetic Regulation

ARUSHI VARSHNEY, NANDINI MANICKAM, PETER ORCHARD, ADELAIDE TOVAR, ZHENHAO ZHANG, FAN FENG, TIMO A. LAKKA, MARKKU LAAKSO, SR., JAAKKO TUOMILEHTO, KAREN L. MOHLKE, JACOB KITZMAN, HEIKKI A. KOISTINEN, JIE LIU, MICHAEL BOEHNKE, FRANCIS S. COLLINS, LAURA SCOTT, STEPHEN C. PARKER

Diabetes 2024;73(Supplement_1):2013-LB

https://doi.org/10.2337/db24-2013-LB

Published: 14 June 2024

View article titled, 2013-LB: Population-Scale Skeletal Muscle Single-Nucleus Multiomic Profiling Reveals Extensive Context-Specific Genetic Regulation

Meeting Abstracts

2012-LB: Type 2 Diabetes GWAS Signal C2CD4A/B Insulin Resistance Mechanisms in Skeletal Muscle

IBIERE L. EPELLE, ARUSHI VARSHNEY, PETER ORCHARD, ZHENHAO ZHANG, FAN FENG, MARKKU LAAKSO, SR., JAAKKO TUOMILEHTO, TIMO A. LAKKA, KAREN L. MOHLKE, MICHAEL BOEHNKE, LAURA SCOTT, HEIKKI A. KOISTINEN, FRANCIS S. COLLINS, JIE LIU, STEPHEN C. PARKER

Diabetes 2024;73(Supplement_1):2012-LB

https://doi.org/10.2337/db24-2012-LB

Published: 14 June 2024

View article titled, 2012-LB: Type 2 Diabetes GWAS Signal <em>C2CD4A/B</em> Insulin Resistance Mechanisms in Skeletal Muscle

Meeting Abstracts

870-P: Long-Term Efficacy and Safety of Crisugabalin Besilate in Chinese patients with Diabetic Peripheral Neuropathic Pain

TINGTING ZHANG, XIAOHUI GUO, HONGMEI LI, JIANHUA MA, LI YUKUN, CHENGXIA JIANG, JIE LIU

Diabetes 2024;73(Supplement_1):870-P

https://doi.org/10.2337/db24-870-P

Published: 14 June 2024

View article titled, 870-P: Long-Term Efficacy and Safety of Crisugabalin Besilate in Chinese patients with Diabetic Peripheral Neuropathic Pain

Meeting Abstracts

1999-LB: GenomicKB—A Knowledge Graph for Human Genomic Data to Advance Understanding of Diabetes

FAN FENG, FEITONG TANG, YIJIA GAO, DONGYU ZHU, TIANJUN LI, SHUYUAN YANG, YUAN YAO, YUANHAO HUANG, DIANE C. SAUNDERS, STEPHEN C. PARKER, JP CARTAILLER, MARCELA BRISSOVA, JIE LIU

Diabetes 2024;73(Supplement_1):1999-LB

https://doi.org/10.2337/db24-1999-LB

Published: 14 June 2024

View article titled, 1999-LB: GenomicKB—A Knowledge Graph for Human Genomic Data to Advance Understanding of Diabetes

Journal Articles

Regulatory Role of NF-κB on HDAC2 and Tau Hyperphosphorylation in Diabetic Encephalopathy and the Therapeutic Potential of Luteolin

Qian Fu, Yilin Song, Zhaoke Ling, Jie Liu, Qingqing Kong, Xin Hao, Ting Xu, Qiang Zhang, Yi Liu

Diabetes 2024;73(9):1513–1526

https://doi.org/10.2337/db23-0969

Published: 13 June 2024

View article titled, Regulatory Role of NF-κB on HDAC2 and Tau Hyperphosphorylation in Diabetic Encephalopathy and the Therapeutic Potential of Luteolin

Meeting Abstracts

1683-P: High-Fat Diet Downregulates CREG1 in the Liver via DNA Methylation

YANMEI QI, JIE LIU, JOSHUA C. CHAO, SAUM A. RAHIMI, LEONARD Y. LEE, SHAOHUA LI

Diabetes 2023;72(Supplement_1):1683-P

https://doi.org/10.2337/db23-1683-P

Published: 20 June 2023

View article titled, 1683-P: High-Fat Diet Downregulates CREG1 in the Liver via DNA Methylation

Meeting Abstracts

291-OR: CREG1 Regulates Hepatic Insulin Sensitivity and Insulin Receptor Trafficking

YANMEI QI, JIE LIU, JOSHUA C. CHAO, SAUM A. RAHIMI, LEONARD Y. LEE, SHAOHUA LI

Diabetes 2023;72(Supplement_1):291-OR

https://doi.org/10.2337/db23-291-OR

Published: 20 June 2023

View article titled, 291-OR: CREG1 Regulates Hepatic Insulin Sensitivity and Insulin Receptor Trafficking

Meeting Abstracts

865-P: Long-Term Ertugliflozin Treatment and Incidence of Hypoglycemia: Analyses from VERTIS CV

SAMUEL DAGOGO-JACK, CHRISTOPHER P. CANNON, DAVID CHERNEY, FRANCESCO COSENTINO, DARREN K. MCGUIRE, JIE LIU, CHIH-CHIN LIU, ROBERT FREDERICH, JAMES P. MANCUSO, RICHARD E. PRATLEY

Diabetes 2022;71(Supplement_1):865-P

https://doi.org/10.2337/db22-865-P

Published: 01 June 2022

View article titled, 865-P: Long-Term Ertugliflozin Treatment and Incidence of Hypoglycemia: Analyses from VERTIS CV

Meeting Abstracts

791-P: Ertugliflozin in Older Patients with Type 2 Diabetes (T2D): An Analysis from VERTIS CV

RICHARD E. PRATLEY, SAMUEL DAGOGO-JACK, BERNARD CHARBONNEL, DAVID CHERNEY, FRANCESCO COSENTINO, DARREN K. MCGUIRE, MARGARET N. ESSEX, PHILIP L.S. JONES, JIE LIU, INGRID A. ADAMSONS, DAVID LAWRENCE, WEICHUNG J. SHIH, CHRISTOPHER P. CANNON

Diabetes 2021;70(Supplement_1):791-P

https://doi.org/10.2337/db21-791-P

Published: 01 June 2021

View article titled, 791-P: Ertugliflozin in Older Patients with Type 2 Diabetes (T2D): An Analysis from VERTIS CV

Meeting Abstracts

208-LB: Peripheral CB1 Inverse Agonism Improves Metabolism in DIO Mice Independent of Hepatic FGF21

JIE LIU

Diabetes 2021;70(Supplement_1):208-LB

https://doi.org/10.2337/db21-208-LB

Published: 01 June 2021

View article titled, 208-LB: Peripheral CB1 Inverse Agonism Improves Metabolism in DIO Mice Independent of Hepatic FGF21

Meeting Abstracts

783-P: Cardiorenal Outcomes with Ertugliflozin by Baseline (BL) Glucose-Lowering Agent (GLA): An Analysis from VERTIS CV

BERNARD CHARBONNEL, SAMUEL DAGOGO-JACK, CHRISTOPHER P. CANNON, DAVID CHERNEY, FRANCESCO COSENTINO, DARREN K. MCGUIRE, WEICHUNG J. SHIH, JIE LIU, ANNPEY PONG, IRA GANTZ, ROBERT FREDERICH, JAMES P. MANCUSO, RICHARD E. PRATLEY

Diabetes 2021;70(Supplement_1):783-P

https://doi.org/10.2337/db21-783-P

Published: 01 June 2021

View article titled, 783-P: Cardiorenal Outcomes with Ertugliflozin by Baseline (BL) Glucose-Lowering Agent (GLA): An Analysis from VERTIS CV

Meeting Abstracts

785-P: Ertugliflozin (ERTU) Delays Insulin Initiation and Reduces Insulin Dose Requirements in Patients with Type 2 Diabetes (T2D): An Analysis From VERTIS CV

SAMUEL DAGOGO-JACK, ROBERT FREDERICH, BERNARD CHARBONNEL, JIE LIU, CHRISTOPHER P. CANNON, HARRY SHI, DARREN K. MCGUIRE, DAVID CHERNEY, FRANCESCO COSENTINO, WEICHUNG J. SHIH, URSZULA MASIUKIEWICZ, IRA GANTZ, RICHARD E. PRATLEY

Diabetes 2021;70(Supplement_1):785-P

https://doi.org/10.2337/db21-785-P

Published: 01 June 2021

View article titled, 785-P: Ertugliflozin (ERTU) Delays Insulin Initiation and Reduces Insulin Dose Requirements in Patients with Type 2 Diabetes (T2D): An Analysis From VERTIS CV

Meeting Abstracts

786-P: Glycemic Efficacy and Safety of Ertugliflozin (ERTU) in Patients with Type 2 Diabetes (T2D) and Chronic Kidney Disease Stage 3 (CKD 3): An Analysis from VERTIS CV

SAMUEL DAGOGO-JACK, RICHARD E. PRATLEY, DAVID CHERNEY, BERNARD CHARBONNEL, DARREN K. MCGUIRE, FRANCESCO COSENTINO, WEICHUNG J. SHIH, JIE LIU, ROBERT FREDERICH, JAMES P. MANCUSO, ANNASWAMY RAJI, IRA GANTZ

Diabetes 2021;70(Supplement_1):786-P

https://doi.org/10.2337/db21-786-P

Published: 01 June 2021

View article titled, 786-P: Glycemic Efficacy and Safety of Ertugliflozin (ERTU) in Patients with Type 2 Diabetes (T2D) and Chronic Kidney Disease Stage 3 (CKD 3): An Analysis from VERTIS CV

Meeting Abstracts

1210-P: Pooled Analysis of the Safety and Efficacy of Ertugliflozin in the Elderly

RICHARD E. PRATLEY, SAMUEL DAGOGO-JACK, BERNARD CHARBONNEL, SHRITA M. PATEL, MARY A. HICKMAN, JIE LIU, LISA TARASENKO, MISOO C. ELLISON, IRA GANTZ, STEVEN G. TERRA

Diabetes 2019;68(Supplement_1):1210-P

https://doi.org/10.2337/db19-1210-P

Published: 01 June 2019

View article titled, 1210-P: Pooled Analysis of the Safety and Efficacy of Ertugliflozin in the Elderly

Meeting Abstracts

1197-P: Two-Year Effects of Ertugliflozin on Renal Function

DAVID CHERNEY, HIDDO L. HEERSPINK, ROBERT FREDERICH, MARIO MALDONADO, ANNPEY PONG, ZHI JIN XU, JIE LIU, JAMES P. MANCUSO, IRA GANTZ, STEVEN G. TERRA

Diabetes 2019;68(Supplement_1):1197-P

https://doi.org/10.2337/db19-1197-P

Published: 01 June 2019

View article titled, 1197-P: Two-Year Effects of Ertugliflozin on Renal Function

Meeting Abstracts

2353-PUB: Efficacy and Safety of Ertugliflozin in Hispanic/Latino Patients (Pts) with Type 2 Diabetes Mellitus (T2DM)

JIE LIU, LISA TARASENKO, MISOO C. ELLISON, ANNPEY PONG, SUSAN HUYCK, JAMES P. MANCUSO, STEVEN G. TERRA, IRA GANTZ

Diabetes 2019;68(Supplement_1):2353-PUB

https://doi.org/10.2337/db19-2353-PUB

Published: 01 June 2019

View article titled, 2353-PUB: Efficacy and Safety of Ertugliflozin in Hispanic/Latino Patients (Pts) with Type 2 Diabetes Mellitus (T2DM)

Journal Articles

Erratum. SRY-Box Containing Gene 4 Promotes Liver Steatosis by Upregulation of SREBP-1c. Diabetes 2018;67: 2227–2238

Yang Jiao, Jiejie Zhao, Zhijian Zhang, Min Li, Xi Yu, Yanying Yang, Jie Liu, Shengjie Liao, Duanzhuo Li, Yuxing Wang, Die Zhang, Yulu Chen, Guojun Shi, Bin Liu, Yan Lu, Xiaoying Li

Diabetes 2019;68(1):235

https://doi.org/10.2337/db19-er01b

Published: 07 November 2018

View article titled, Erratum. SRY-Box Containing Gene 4 Promotes Liver Steatosis by Upregulation of SREBP-1c. Diabetes 2018;67: 2227–2238

Journal Articles

SRY-Box Containing Gene 4 Promotes Liver Steatosis by Upregulation of SREBP-1c

Yang Jiao, Jiejie Zhao, Zhijian Zhang, Min Li, Xi Yu, Yanying Yang, Jie Liu, Shengjie Liao, Duanzhuo Li, Yuxing Wang, Die Zhang, Yulu Chen, Guojun Shi, Bin Liu, Yan Lu, Xiaoying Li

Diabetes 2018;67(11):2227–2238

https://doi.org/10.2337/db18-0184

Published: 04 September 2018

View article titled, SRY-Box Containing Gene 4 Promotes Liver Steatosis by Upregulation of SREBP-1c

Includes: Supplementary data

Meeting Abstracts

A Pooled Analysis of the Efficacy and Safety of Ertugliflozin as Add-On Therapy to Metformin

ROBERTO A. CALLE, JIE LIU, SUSAN HUYCK, LARRY WU, ANNPEY PONG, JAMES P. MANCUSO, STEVEN TERRA, BRETT LAURING

Diabetes 2018;67(Supplement_1):1140-P

https://doi.org/10.2337/db18-1140-P

Published: 01 July 2018

View article titled, A Pooled Analysis of the Efficacy and Safety of Ertugliflozin as Add-On Therapy to Metformin

Meeting Abstracts

Efficacy and Safety of Ertugliflozin across Racial Groups in Patients with Type 2 Diabetes Mellitus (T2DM)

JIE LIU, LISA TARASENKO, ANNPEY PONG, SUSAN HUYCK, LARRY WU, JAMES P. MANCUSO, STEVEN TERRA, BRETT LAURING

Diabetes 2018;67(Supplement_1):1132-P

https://doi.org/10.2337/db18-1132-P

Published: 01 July 2018

View article titled, Efficacy and Safety of Ertugliflozin across Racial Groups in Patients with Type 2 Diabetes Mellitus (T2DM)

NARROW

2013-LB: Population-Scale Skeletal Muscle Single-Nucleus Multiomic Profiling Reveals Extensive Context-Specific Genetic Regulation

2012-LB: Type 2 Diabetes GWAS Signal C2CD4A/B Insulin Resistance Mechanisms in Skeletal Muscle

870-P: Long-Term Efficacy and Safety of Crisugabalin Besilate in Chinese patients with Diabetic Peripheral Neuropathic Pain

1999-LB: GenomicKB—A Knowledge Graph for Human Genomic Data to Advance Understanding of Diabetes

Regulatory Role of NF-κB on HDAC2 and Tau Hyperphosphorylation in Diabetic Encephalopathy and the Therapeutic Potential of Luteolin

1683-P: High-Fat Diet Downregulates CREG1 in the Liver via DNA Methylation

291-OR: CREG1 Regulates Hepatic Insulin Sensitivity and Insulin Receptor Trafficking

865-P: Long-Term Ertugliflozin Treatment and Incidence of Hypoglycemia: Analyses from VERTIS CV

791-P: Ertugliflozin in Older Patients with Type 2 Diabetes (T2D): An Analysis from VERTIS CV

208-LB: Peripheral CB1 Inverse Agonism Improves Metabolism in DIO Mice Independent of Hepatic FGF21

783-P: Cardiorenal Outcomes with Ertugliflozin by Baseline (BL) Glucose-Lowering Agent (GLA): An Analysis from VERTIS CV

785-P: Ertugliflozin (ERTU) Delays Insulin Initiation and Reduces Insulin Dose Requirements in Patients with Type 2 Diabetes (T2D): An Analysis From VERTIS CV

786-P: Glycemic Efficacy and Safety of Ertugliflozin (ERTU) in Patients with Type 2 Diabetes (T2D) and Chronic Kidney Disease Stage 3 (CKD 3): An Analysis from VERTIS CV

1210-P: Pooled Analysis of the Safety and Efficacy of Ertugliflozin in the Elderly

1197-P: Two-Year Effects of Ertugliflozin on Renal Function

2353-PUB: Efficacy and Safety of Ertugliflozin in Hispanic/Latino Patients (Pts) with Type 2 Diabetes Mellitus (T2DM)

Erratum. SRY-Box Containing Gene 4 Promotes Liver Steatosis by Upregulation of SREBP-1c. Diabetes 2018;67: 2227–2238

SRY-Box Containing Gene 4 Promotes Liver Steatosis by Upregulation of SREBP-1c

A Pooled Analysis of the Efficacy and Safety of Ertugliflozin as Add-On Therapy to Metformin

Efficacy and Safety of Ertugliflozin across Racial Groups in Patients with Type 2 Diabetes Mellitus (T2DM)

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