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Johannes D Veldhuis
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Journal Articles

Loss of Inverse Relationship Between Pulsatile Insulin and Glucagon Secretion in Patients With Type 2 Diabetes

Björn A. Menge, Lena Grüber, Signe M. Jørgensen, Carolyn F. Deacon, Wolfgang E. Schmidt, Johannes D. Veldhuis, Jens J. Holst, Juris J. Meier
Journal: Diabetes
Diabetes 2011;60(8):2160–2168
https://doi.org/10.2337/db11-0251
Published: 18 July 2011
View article titled, Loss of Inverse Relationship Between Pulsatile Insulin and Glucagon Secretion in Patients With Type 2 Diabetes
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Journal Articles

Human Islet Amyloid Polypeptide Oligomers Disrupt Cell Coupling, Induce Apoptosis, and Impair Insulin Secretion in Isolated Human Islets

Robert A. Ritzel, Juris J. Meier, Chia-Yu Lin, Johannes D. Veldhuis, Peter C. Butler
Journal: Diabetes
Diabetes 2007;56(1):65–71
https://doi.org/10.2337/db06-0734
Published: 01 January 2007
View article titled, Human Islet Amyloid Polypeptide Oligomers Disrupt Cell Coupling, Induce Apoptosis, and Impair Insulin Secretion in Isolated Human Islets
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Journal Articles

Mechanisms of Impaired Fasting Glucose and Glucose Intolerance Induced by a ∼50% Pancreatectomy

Aleksey V. Matveyenko, Johannes D. Veldhuis, Peter C. Butler
Journal: Diabetes
Diabetes 2006;55(8):2347–2356
https://doi.org/10.2337/db06-0345
Published: 01 August 2006
View article titled, Mechanisms of Impaired Fasting Glucose and Glucose Intolerance Induced by a ∼50% Pancreatectomy
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Journal Articles

Intrahepatic Transplanted Islets in Humans Secrete Insulin in a Coordinate Pulsatile Manner Directly Into the Liver

Juris J. Meier, Irene Hong-McAtee, Ryan Galasso, Johannes D. Veldhuis, Antoinette Moran, Bernhard J. Hering, Peter C. Butler
Journal: Diabetes
Diabetes 2006;55(8):2324–2332
https://doi.org/10.2337/db06-0069
Published: 01 August 2006
View article titled, Intrahepatic Transplanted Islets in Humans Secrete Insulin in a Coordinate Pulsatile Manner Directly Into the Liver
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Journal Articles

Postprandial Suppression of Glucagon Secretion Depends on Intact Pulsatile Insulin Secretion: Further Evidence for the Intraislet Insulin Hypothesis

Juris J. Meier, Lise L. Kjems, Johannes D. Veldhuis, Pierre Lefèbvre, Peter C. Butler
Journal: Diabetes
Diabetes 2006;55(4):1051–1056
https://doi.org/10.2337/diabetes.55.04.06.db05-1449
Published: 01 April 2006
View article titled, Postprandial Suppression of Glucagon Secretion Depends on Intact Pulsatile Insulin Secretion: <subtitle>Further Evidence for the Intraislet Insulin Hypothesis </subtitle>
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Journal Articles

Pulsatile Insulin Secretion Dictates Systemic Insulin Delivery by Regulating Hepatic Insulin Extraction In Humans

Juris J. Meier, Johannes D. Veldhuis, Peter C. Butler
Journal: Diabetes
Diabetes 2005;54(6):1649–1656
https://doi.org/10.2337/diabetes.54.6.1649
Published: 01 June 2005
View article titled, Pulsatile Insulin Secretion Dictates Systemic Insulin Delivery by Regulating Hepatic Insulin Extraction In Humans
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Journal Articles

Pulsatile Insulin Secretion: Detection, Regulation, and Role in Diabetes

Niels Pørksen, Malene Hollingdal, Claus Juhl, Peter Butler, Johannes D. Veldhuis, Ole Schmitz
Journal: Diabetes
Diabetes 2002;51(suppl_1):S245–S254
https://doi.org/10.2337/diabetes.51.2007.S245
Published: 01 February 2002
View article titled, Pulsatile Insulin Secretion: Detection, Regulation, and Role in Diabetes
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Journal Articles

Effects of Fasting on Physiologically Pulsatile Insulin Release in Healthy Humans

Claus Juhl, Thorbjørn Grøfte, Peter C. Butler, Johannes D. Veldhuis, Ole Schmitz, Niels Pørksen
Journal: Diabetes
Diabetes 2002;51(suppl_1):S255–S257
https://doi.org/10.2337/diabetes.51.2007.S255
Published: 01 February 2002
View article titled, Effects of Fasting on Physiologically Pulsatile Insulin Release in Healthy Humans
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Journal Articles

Decrease in β-Cell Mass Leads to Impaired Pulsatile Insulin Secretion, Reduced Postprandial Hepatic Insulin Clearance, and Relative Hyperglucagonemia in the Minipig

Lise L. Kjems, Barbara M. Kirby, Elizabeth M. Welsh, Johannes D. Veldhuis, Marty Straume, Susan S. McIntyre, Dongchang Yang, Pierre Lefèbvre, Peter C. Butler
Journal: Diabetes
Diabetes 2001;50(9):2001–2012
https://doi.org/10.2337/diabetes.50.9.2001
Published: 01 September 2001
View article titled, Decrease in β-Cell Mass Leads to Impaired Pulsatile Insulin Secretion, Reduced Postprandial Hepatic Insulin Clearance, and Relative Hyperglucagonemia in the Minipig
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Journal Articles

Acute and Short-Term Administration of a Sulfonylurea (Gliclazide) Increases Pulsatile Insulin Secretion in Type 2 Diabetes

Claus B. Juhl, Niels Pørksen, Steven M. Pincus, Åge P. Hansen, Johannes D. Veldhuis, Ole Schmitz
Journal: Diabetes
Diabetes 2001;50(8):1778–1784
https://doi.org/10.2337/diabetes.50.8.1778
Published: 01 August 2001
View article titled, Acute and Short-Term Administration of a Sulfonylurea (Gliclazide) Increases Pulsatile Insulin Secretion in Type 2 Diabetes
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Journal Articles

Glucagon-Like Peptide 1 Increases Mass But Not Frequency or Orderliness of Pulsatile Insulin Secretion

Niels Pørksen, Thorbjørn Grøfte, Birgit Nyholm, Jens Juul Holst, Steven M Pincus, Johannes D Veldhuis, Ole Schmitz, Peter C Butler
Journal: Diabetes
Diabetes 1998;47(1):45–49
https://doi.org/10.2337/diab.47.1.45
Published: 01 January 1998
View article titled, Glucagon-Like Peptide 1 Increases Mass But Not Frequency or Orderliness of Pulsatile Insulin Secretion
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Journal Articles

Mechanisms of Sulfonylurea's Stimulation of Insulin Secretion In Vivo: Selective Amplification of Insulin Secretory Burst Mass

Niels K Pørksen, Stephen R Munn, Jeffery L Steers, Ole Schmitz, Johannes D Veldhuis, Peter C Butler
Journal: Diabetes
Diabetes 1996;45(12):1792–1797
https://doi.org/10.2337/diab.45.12.1792
Published: 01 December 1996
View article titled, Mechanisms of Sulfonylurea's Stimulation of Insulin Secretion In Vivo: Selective Amplification of Insulin Secretory Burst Mass
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Journal Articles

Effects of Glucose Ingestion Versus Infusion on Pulsatile Insulin Secretion: The Incretin Effect Is Achieved by Amplification of Insulin Secretory Burst Mass

Niels Pørksen, Stephen Munn, Jeffery Steers, Johannes D Veldhuis, Peter C Butler
Journal: Diabetes
Diabetes 1996;45(10):1317–1323
https://doi.org/10.2337/diab.45.10.1317
Published: 01 October 1996
View article titled, Effects of Glucose Ingestion Versus Infusion on Pulsatile Insulin Secretion: The Incretin Effect Is Achieved by Amplification of Insulin Secretory Burst Mass
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